Natural Health Research Discovery

Each Topic is an Index of Curated Biomedical Research Abstracts

Pharmacological Actions (501)

ALLA B C D E F G H I J L M N O P Q R S T U V W X Z Β
Pharmacological Action NameCumulative Knowledgesort iconAbstractsPDF
Glyoxalase 1 inhibitor11
Ionophores11
Histamine up-regulation11
Hydroxyheptadecatrienoate (HHT) Inhibitor11
IGF-1R expression down-regulation11
Enkephalinase inhibitor11
Eryptotic11
Interleukin-1 beta upregulation11
Tyrosinase Inhibition11
Vitamin D Receptor (VDR) Modulator11
PI3K/Akt/signaling suppression11
Muscle Relaxants: Central11
IRAK-MAPK Modulator11
p300/NF-κB down-regulation11
Alpha-hemolysin inhibitor11
PKM2 downregulation11
Prostaglandin H Synthase-1 (PGHS-1) Inhibits11
Maspin (Protease Inhibitor) Up-Regulation11
Sulfonation11
Cyclin-dependent kinase inhibitor: P16INK411
Glucose transporter-5 (GLUT5) expression down-regulation11
Herbicides11
Dopamine Agonists11
Prostaglandin H Synthase-2 (PGHS-2) Up-Regulation11
Mast Cell Activation Inhibitor11
Molecular Probes11
Contraceptive Agents11
Transient Receptor Potential Melastatin 2 Inhibition11
Leukotriene D4 antagonist11
17beta-hydroxysteroid dehydrogenase inhibitor11
Oxidants11
Arginase 1 (Arg1) up-regulation11
Zinc-dependent metalloproteinase inhibitor11
Superoxide Scavenger11
Antilipolytic11
Hematologic Agents11
Hypomethylating11
E-cadherin down-regulation11
5-HTergic11
Oxytocics11
Phosphodiesterase Inhibitors11
Beta-Defensin-2 Up-Regulation11
β-secretase Inhibitor11
PPAR-Gamma Up-Regulation11
Calcium/calmodulin dependent protein kinase II inhibitor11
Matrix Metalloproteinase-8 Inhibitor11
Neovasculogenesis11
Cryoprotective Agents11
Lactate Dehydrogenase A Inhibitor11
Emmenagogue11
5-Hydroxyeicosatetraenoic acid (5-HETE) Inhibitor11
Astringents11
Akt-SREBP-1 activater11
Phospholipase D Inhibitors11
Cancerous inhibitor of protein phosphatase 2A inhibitor11
Anti-cancer11
S-phase kinase associated protein 2 inhibition11
mTOR/S6K pathway Activator11
Antibiotics: Antifungal11
Human Polymorphonuclear Leukocyte Degranulation Inhibitor11
Dipeptidyl-Peptidase IV Inhibitors11
Endocannabinoid Modulator11
Insect Repellents11
Breast cancer resistance protein (BCRP) down-regulation11
Carbonyl Reductase 1Inhibitor11
Matrix metalloproteinase-14 (MMP-14) inhibitor11
Chondroprotective11
Cyclin-Dependent Kinase 4 Down-Regulation11
Antifibrinolytic Agents11
Hemolytic Agents11
Hypoxia-inducible factor-1 (HIF-1) inhibitor11
Disinfectants11
Fatty Acid Synthesis Inhibitors11
P16 Activation11
Psychedelic11
Matrix metalloproteinase-17 (MMP-17) inhibitor11
Serine Proteinase Inhibitors11
Neuroimmunomodulation11
Cytotoxins11
Insecticides21
Fertility Agents21
Abortifacient Agents21
Adrenergic Agents21
Peroxisome Proliferators21
Angiogenesis Modulating Agents21
Serotonin Agonists21
Cicatrizing21
Stomachic21
Cyclin-Dependent Kinase Inhibitor: P1622
Death receptor up-regulation21
Antinitrosation21
Environmental Pollutants21
Uncoupling Agents21
C-Jun N-Terminal Kinases (JNK) Modulator22
Remyelination21
Myorelaxant21
Coccidiostats21
GSH-Px Up-Regulation21
Leukotriene C4 Downregulation22
1-Glutamine Uptake Inhibitor22
Ovogenic21
Phase I Detoxification Enzyme Inhibitor21
Central Nervous System Agents21
Myosin heavy chain alpha (MHCalpha) reducer21
Histamine Agents21
Gene Protective21
Akt-dependent HO-1 expression up-regulation21
Calcium Desensitizer21
Nootropic Agents21
JAM3 gene down-regulation21
Histamine Agonists21
Immunomodulatory: CD8+ Up-regulation21
Incretin Modulator21
Enzyme Inhibitors: Maltase Inhibition21
Follicle-stimulating hormone receptor (FSHR) up-regulation21
Adenosine Monophosphate (AMP)-Activated Protein Kinase (AMPK) Down-Regulation21
Arginine Vasopressin (AVP) up-regulation.21
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor22
RANTES (CCL5) Inhibitor22
Thromboxane B2 Inhibitor22
Noradrenergic21
Human androgen receptor (AR) antagonist22
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)22
Food Preservatives22
Antiparkinson Agents21
Anesthetics21
Progestagenic21
Receptor-Related Orphan Receptor (ROR)-Alpha1 Inhibitor21
Antidiuretic Agents21
Neutrophil Activation: Down-Regulation21
Glycine Agents21
Lymphagogue21
Tumor Necrosis Factor (TNF) Alpha Upregulation21
P-glycoprotein Inhibitors22
Progesterone receptor (PR) up-regulation21
Redox Balancer21
Hydroperoxidase Inhibitor21
Endothelin-1 Inhibitor21
ER beta receptor up-regulation21
Vascular Endothelial Growth Factor C Inhibitor21
Adjuvants: Immunologic21
Bronchoconstrictor Agents21
Muscarinic Agonists21
Opioid Endogenous Up-regulation21
Interleukin-15 downregulation32
Quinone Reductase-Inducer32
Glucose transporter-2 (GLUT2) expression down-regulation32
Estradiol 3-glucuronide enhancer33
Adrenergic beta-Agonists32
Matrix metalloproteinase-8 (MMP-8) inhibitor32
Chemokine (C-C motif) Ligand 2 (CCL2) Down-Regulation32
Cholinergic Agents32
Survival protein down-regulation32
Cholinergic Antagonists32
Forkhead Transcription Factor Family O (FOXO) Modulator32
Atrial Natriuretic Factor Modulation32
Histamine down-regulation32
Steroidogenesis32
Cyclin-Dependent Kinase Inhibitor33
NF-kappa-B-inducing kinase (NIK) modulator32
TRAIL sensitizer32
Anticholinergic42
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Upregulation42
Erythropoietic43
Adrenergic alpha-Agonists43
Phase I Detoxification Enzyme Inducer42
Angiotensin II Type 1 Receptor Blockers42
SGLT1 inducer42
Antithrombotic42
Matrix Metalloproteinase-7 (MMP-7) Inhibitor41
Monoamine Oxidase Inhibitors42
Contraceptive Agents: Male42
Thrombolytic42
Anti-Inflammatory Agents: Non-Steroidal42
Vascular Endothelial Growth Factor A Enhancer42
Ghrelin Up-regulation42
Immunomodulatory: Regulatory T Cell Up-Regulation42
Schistosomicides42
Intracellular adhesion molecule-1 (ICAM-1)43
Mitochondrial Superoxide Dismutase Upregulation43
HIV Fusion Inhibitors54
Antacids51
Spermicidal Activity51
Insulin-Like Growth Factor Enhancer/Upregulation53
Extracellular Signal-Regulated Kinases Modulator54
AMP-activated protein kinase modulation64
Trypsin Inhibitors64
Monoaminergic63
5-Lipoxygenase Inhibitor65
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation72
Antigiardial agents74
Vascular smooth muscle cell (VSMC) inhibitor75
Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK72
Excitatory Amino Acid Agonists74
Insecticidal84
Insulin-mimetic96
Redox Modulator95
Gastric Inhibitory Polypeptide Up-Regulation101
Immune Enhancing Properties101
Insulin Antagonists101
Immunostimulatory: IgA Production Up-Regulation101
Antilipemic Agents101
Isoprostane Down-Regulation101
Immunomodulatory: CD23+ Mature Macrophage Down-Regulation101
Drug sparing101
Respiratory System Agents101
Glutathione peroxidase 1 (GPx1) inhibitors101
Hormones101
Neurotransmitter Uptake Inhibitors101
Interleukin-23 Downregulation101
Diacylglyceride acyltransferase 1 (DGAT1) Inhibition101
Immunomodulatory: Immunoglobulin G up-regulation101
Interleukin 1 receptor antagonist (IL-1Ra) up-regulation101
Oxytocin inducer101
Peptide YY (PYY) Down-regulation101
STAT3 Activation108
NOX2 inhibitor101
Interleukin-3 upregulation101
Intracellular adhesion molecule down-regulation101
Fatty Acid Oxidation101
Alkylating Agents101
Phosphorylase Kinase Inhibitors101
Interleukin-13 Up-Regulation101
PER2 Protein Expression Up-regulation101
Mitogen-activated protein kinase inhibitors112
Insulinotrophic117
Interleukin-1 receptor antagonist112
Mitogen-activated protein kinase kinase 4 (MEK4)112
Dopamine Agents122
Insulin Receptor Modulator122
Carminative122
Vasopressin Inhibitor122
VEGFR3 inhibition123
Mucolytic122
Immunomodulatory: T-Cell down-regulation122
Anti-edemic122
Leukotriene B4 downregulation134
Matrix Metalloproteinase-12 (MMP-12) Inhibitor137
Topoisomerase I inhibitor1311
Anti-collagenase132
Cell Differentiation Inducer1411
Teratogens143
Paraptosis1414
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor144
Hepatocyte growth factor (HGF) inhibitor154
Antipsychotic Agents152
Antioxidant Effects154
Antitubercular Agents155
Protease Inhibitors156
Survivin Down-Regulation1513
P38 Mitogen-Activated Protein Kinase Modulator1611
Peptide YY (PYY) Up-Regulation164
Anticoagulants1815
Topoisomerase II Inhibitor1917
Neurominidase Inhibitor2019Downloadable Document
Hypnotics and Sedatives206
Adenosine deaminase inhibitor207
Cholecystokinin Releaser202
Fibroblast growth factor 21 upregulation2111
Chymotrypsin Inhibitor212
Viral Hemagglutinin Inhibitor2216Downloadable Document
Leptin Down-Regulation238
Natriuretic Agents234
Interleukin-22 Downregulation2410
Detoxifier: Radionuclide Removal255
Androgen Antagonists255
Glucose Uptake Optimization269
Adiponectin Down-Regulation278
Bax/Bcl2 Ratio: Decrease2918
Enzyme Activators2918
Protein Kinase Inhibitors2919Downloadable Document
Interleukin-8 upregulation303
HIV Protease Inhibitors3119Downloadable Document
Antiurolithiatic319
Carcinogens312
Transforming growth factor beta (TGF-β) upregulation3214
Interleukin-6 upregulation3211
Caspase-8 activation3222
Cholecystokinin (CCK) Up-regulation345
Uterotonic3411Downloadable Document
Spermatogenic3412
5-Lipoxygenase Inhibitor3521
Antimycobacterial3519Downloadable Document
Glucagon Like Peptide 1 (GLP-1) Down-Regulation356
Ghrelin Down-Regulation366
Insulin Down-Regulation387
SIRT1 Activator3923
Iron Chelating Agents4015
Bax/Bcl2 ratio: Increase4032
Interferon Inducers4110
Chelating Agents4121
Appetite Depressants429
Laxative426
Tumor Necrosis Factor (TNF) Alpha Enhancer4413
Histamine Antagonists4517Downloadable Document
Histamine Antagonists4517Downloadable Document
Enzyme Inhibitors: Pancreatic Lipase4619
Reverse Transcriptase Inhibitors4729Downloadable Document
Interleukin-12 upregulation4813
Quorum Sensing Inhibition4949
Anti-Retroviral Agents4918
Lipolytic4918Downloadable Document
Lipoxygenase Inhibitors5027Downloadable Document
Osteogenic5212
STAT3 Inhibitor5331
Cholagogues and Choleretics5412Downloadable Document
Thermogenic579
Heme oxygenase-1 inducer5739
Interferon Gamma Reducer5824
Estrogen Receptor Modulators5834Downloadable Document
Proteasome Inhibitors5940Downloadable Document
Fertility Agents: Male6014
Interferon-gamma (IFN-gamma) inducer6018
Antiprotozoal Agents6132
Anti-pyretic6224
Vascular Endothelial Growth Factor Regulator6229Downloadable Document
Malonaldehyde (MDA) Down-Regulation6215
Appetite Suppresant6414
Cyclooxygenase 1 Inhibitor6548Downloadable Document
Aphrodisiac6722Downloadable Document
Anti-Proliferative6755Downloadable Document
Xanthine oxidase inhibitor6934Downloadable Document
NF-E2-Related Factor-2 (Nrf2) Modulator6939
Caspase-9 Activation7046
Neurorestorative7121Downloadable Document
Galactogogue738
Cyclooxygenase Inhibitors7442Downloadable Document
Anti-thrombotic7632Downloadable Document
Cytotoxic7660
Bronchodilator Agents7815Downloadable Document
Anti-Cachexic Agents7926
Immunosuppressive Agents8043Downloadable Document
Neuroplasticity enhancement8323
Insulin-Like Growth Factor Inhibition/Downregulation8618Downloadable Document
Epidermal growth factor receptor (EGFR) inhibitor8760Downloadable Document
Angiogenesis Inducing Agents8845
Fertility Agents: Female9018
interleukin-13 down-regulation9047
DNA Repair Up-regulation9327
Phase II Detoxification Enzyme Inducer9552Downloadable Document
Telomerase Inhibitor9562Downloadable Document
Histone deacetylase inhibitor9869Downloadable Document
Calcium Channel Blockers9829Downloadable Document
Angiotensin-Converting Enzyme Inhibitors9954Downloadable Document
Matrix metalloproteinase-1 (MMP-1) inhibitor9959
Interleukin-1 alpha downregulation10242Downloadable Document
Interleukin-10 upregulation10524
Cardiotonic Agents10610
Cyclin D1 Down-Regulation10679
Interleukin-4 upregulation11342
Leishmanicidal11879Downloadable Document
Interleukin-5 downregulation12049
Insulin-releasing12249Downloadable Document
Interleukin-2 Downregulation12351
Vascular Cell Adhesion Molecule-1 Inhibitor12334Downloadable Document
Heat Shock Protein Inducer12648Downloadable Document
Glucagon Like peptide 1 (GLP-1) Up-regulation12935Downloadable Document
Interleukin-18 down-regulation13261
Anti-HIV Agents13384Downloadable Document
Caspase-3 Activation13790Downloadable Document
Anti-Platelet13747Downloadable Document
Telomerase Upregulation13734Downloadable Document
Interleukin-12 downregulation13953
Antispasmodic14037Downloadable Document
Matrix Metalloproteinase-13 (MMP-13) Inhibitor14566
Anti-Tumor15476Downloadable Document
P21 Activation160119
Anti-Adipogenic16485Downloadable Document
Antimutagenic Agents16499Downloadable Document
Matrix metalloproteinase-3 (MMP-3) inhibitor16968
Acetylcholinesterase Inhibitor17095Downloadable Document
Autophagy Inhibitors175115
Alpha-amylase inhibitor175110
Immunomodulatory: Th17 downregulation17781
Vascular Endothelial Growth Factor A Inhibitor17997Downloadable Document
Neuritogenic18589Downloadable Document
Interleukin-17 downregulation19385
Prostaglandin PGE2 downregulation19388Downloadable Document
Anti-Glycation Agents197100
Platelet Aggregation Inhibitors20045Downloadable Document
Cardiovascular Agents20132Downloadable Document
Postaglandin PGE2 downregulation202110
Transforming growth factor beta (TGF-β) inhibitor203106
Uricosuric Agents20544
Vasoprotective20752
Wnt/β-catenin signaling pathway modulation208149
Antiparasitic Agents208121Downloadable Document
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor214142
Neurogenesis215109
Adiponectin upregulation21739
Telomere Protective23129
Nitric Oxide Enhancer26176Downloadable Document
Catalase Up-Regulation264112
Dermatologic Agents27232Downloadable Document
Alpha-glucosidase inhibitor274201Downloadable Document
Anti-Asthmatic Agents28671
Radiosensitizer291182Downloadable Document
Glutathione Upregulation29996Downloadable Document
Interleukin-10 downregulation335128Downloadable Document
Anti-Angiogenic347234Downloadable Document
Anti-atherogenic348120
Interleukin-4 downregulation355128Downloadable Document
Pancreato Protective Agents358194
Regenerative408172
Vascular Endothelial Growth Factor Inhibitors435247
Antidiarrheals43987
Anti-Allergic Agents442150Downloadable Document
Photoprotective446198
Brain-derived neurotrophic factor modulator458166
Hypotensive46763Downloadable Document
Anxiolytic47566Downloadable Document
Genoprotective477177Downloadable Document
Angiogenesis Inhibitors488296
Antifungal Agents494306Downloadable Document
Nitric Oxide Inhibitor498258Downloadable Document
Autophagy Up-regulation518349Downloadable Document
Anti-Ulcer Agents523184Downloadable Document
Bcl-2 protein down-regulation553407Downloadable Document
Interleukin-8 downregulation581231Downloadable Document
Tumor Suppressor Protein p53 Upregulation585431Downloadable Document
Heme oxygenase-1 up-regulation624373
Vasodilator Agents626169Downloadable Document
Immunostimulatory633192Downloadable Document
Detoxifier644202Downloadable Document
Antinoceceptive647197Downloadable Document
Cytoprotective659326
Anticonvulsants678189Downloadable Document
Enzyme Inhibitors692347Downloadable Document
Matrix metalloproteinase-2 (MMP-2) inhibitor727442Downloadable Document
Prophylactic Agents780182
Matrix metalloproteinase-9 (MMP-9) inhibitor786505Downloadable Document
Anti-Fibrotic924463Downloadable Document
Gastroprotective955388Downloadable Document
Osteoprotective971351
MicroRNA modulator1023618
Chemosensitizer1124854Downloadable Document
Insulin Sensitizers1185244Downloadable Document
Antimicrobial1209582Downloadable Document
Superoxide Dismutase Up-regulation1403551Downloadable Document
Nrf2 activation1584916
Cyclooxygenase 2 Inhibitors1589926Downloadable Document
Radioprotective1668521Downloadable Document
Cell cycle arrest16781348Downloadable Document
Antineoplastic Agents18471170Downloadable Document
Anticarcinogenic Agents1890889Downloadable Document
Antiviral Agents19571034Downloadable Document
Anti-metastatic19721481Downloadable Document
Malondialdehyde Down-regulation2065678Downloadable Document
Chemoprotective Agents2322906
Chemotherapeutic23281086
Renoprotective24041075Downloadable Document
Anti-Bacterial Agents28941251Downloadable Document
Anti-Apoptotic29051672Downloadable Document
Anti-Anxiety Agents2913487
Interleukin-1 beta downregulation30411567Downloadable Document
Anticholesteremic Agents3078530Downloadable Document
Gastrointestinal Agents3145843
Analgesics3498646Downloadable Document
NF-kappaB Inhibitor35362098Downloadable Document
Immunomodulatory40481475Downloadable Document
Antihypertensive Agents4527683Downloadable Document
Antidepressive Agents4882874Downloadable Document
Interleukin-6 Downregulation50291994Downloadable Document
Hepatoprotective50982264Downloadable Document
Hypolipidemic53581221Downloadable Document
Hypoglycemic Agents53661338Downloadable Document
Chemopreventive53741717Downloadable Document
Cardioprotective53771675Downloadable Document
Tumor Necrosis Factor (TNF) Alpha Inhibitor67362815Downloadable Document
Antiproliferative68015032Downloadable Document
Apoptotic69865304Downloadable Document
Neuroprotective Agents104044396Downloadable Document
Anti-Inflammatory Agents208598334Downloadable Document
Antioxidants215288856Downloadable Document

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