Natural Health Research Discovery

Each Topic is an Index of Curated Biomedical Research Abstracts

Pharmacological Actions (501)

ALLA B C D E F G H I J L M N O P Q R S T U V W X Z Β
Pharmacological Action NameCumulative Knowledgesort iconAbstractsPDF
Antioxidants215288856Downloadable Document
Anti-Inflammatory Agents208598334Downloadable Document
Neuroprotective Agents104044396Downloadable Document
Apoptotic69865304Downloadable Document
Antiproliferative68015032Downloadable Document
Tumor Necrosis Factor (TNF) Alpha Inhibitor67362815Downloadable Document
Cardioprotective53771675Downloadable Document
Chemopreventive53741717Downloadable Document
Hypoglycemic Agents53661338Downloadable Document
Hypolipidemic53581221Downloadable Document
Hepatoprotective50982264Downloadable Document
Interleukin-6 Downregulation50291994Downloadable Document
Antidepressive Agents4882874Downloadable Document
Antihypertensive Agents4527683Downloadable Document
Immunomodulatory40481475Downloadable Document
NF-kappaB Inhibitor35362098Downloadable Document
Analgesics3498646Downloadable Document
Gastrointestinal Agents3145843
Anticholesteremic Agents3078530Downloadable Document
Interleukin-1 beta downregulation30411567Downloadable Document
Anti-Anxiety Agents2913487
Anti-Apoptotic29051672Downloadable Document
Anti-Bacterial Agents28941251Downloadable Document
Renoprotective24041075Downloadable Document
Chemotherapeutic23281086
Chemoprotective Agents2322906
Malondialdehyde Down-regulation2065678Downloadable Document
Anti-metastatic19721481Downloadable Document
Antiviral Agents19571034Downloadable Document
Anticarcinogenic Agents1890889Downloadable Document
Antineoplastic Agents18471170Downloadable Document
Cell cycle arrest16781348Downloadable Document
Radioprotective1668521Downloadable Document
Cyclooxygenase 2 Inhibitors1589926Downloadable Document
Nrf2 activation1584916
Superoxide Dismutase Up-regulation1403551Downloadable Document
Antimicrobial1209582Downloadable Document
Insulin Sensitizers1185244Downloadable Document
Chemosensitizer1124854Downloadable Document
MicroRNA modulator1023618
Osteoprotective971351
Gastroprotective955388Downloadable Document
Anti-Fibrotic924463Downloadable Document
Matrix metalloproteinase-9 (MMP-9) inhibitor786505Downloadable Document
Prophylactic Agents780182
Matrix metalloproteinase-2 (MMP-2) inhibitor727442Downloadable Document
Enzyme Inhibitors692347Downloadable Document
Anticonvulsants678189Downloadable Document
Cytoprotective659326
Antinoceceptive647197Downloadable Document
Detoxifier644202Downloadable Document
Immunostimulatory633192Downloadable Document
Vasodilator Agents626169Downloadable Document
Heme oxygenase-1 up-regulation624373
Tumor Suppressor Protein p53 Upregulation585431Downloadable Document
Interleukin-8 downregulation581231Downloadable Document
Bcl-2 protein down-regulation553407Downloadable Document
Anti-Ulcer Agents523184Downloadable Document
Autophagy Up-regulation518349Downloadable Document
Nitric Oxide Inhibitor498258Downloadable Document
Antifungal Agents494306Downloadable Document
Angiogenesis Inhibitors488296
Genoprotective477177Downloadable Document
Anxiolytic47566Downloadable Document
Hypotensive46763Downloadable Document
Brain-derived neurotrophic factor modulator458166
Photoprotective446198
Anti-Allergic Agents442150Downloadable Document
Antidiarrheals43987
Vascular Endothelial Growth Factor Inhibitors435247
Regenerative408172
Pancreato Protective Agents358194
Interleukin-4 downregulation355128Downloadable Document
Anti-atherogenic348120
Anti-Angiogenic347234Downloadable Document
Glutathione Upregulation29996Downloadable Document
Radiosensitizer291182Downloadable Document
Alpha-glucosidase inhibitor274201Downloadable Document
Catalase Up-Regulation264112
Nitric Oxide Enhancer26176Downloadable Document
Telomere Protective23129
Adiponectin upregulation21739
Neurogenesis215109
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor214142
Antiparasitic Agents208121Downloadable Document
Wnt/β-catenin signaling pathway modulation208149
Vasoprotective20752
Uricosuric Agents20544
Transforming growth factor beta (TGF-β) inhibitor203106
Cardiovascular Agents20132Downloadable Document
Platelet Aggregation Inhibitors20045Downloadable Document
Anti-Glycation Agents197100
Immunomodulatory: Th17 downregulation17781
Alpha-amylase inhibitor175110
Acetylcholinesterase Inhibitor17095Downloadable Document
Anti-Adipogenic16485Downloadable Document
Antimutagenic Agents16499Downloadable Document
Anti-Tumor15476Downloadable Document
Matrix Metalloproteinase-13 (MMP-13) Inhibitor14566
Anti-Platelet13747Downloadable Document
Caspase-3 Activation13790Downloadable Document
Anti-HIV Agents13384Downloadable Document
Glucagon Like peptide 1 (GLP-1) Up-regulation12935Downloadable Document
Heat Shock Protein Inducer12648Downloadable Document
Interleukin-2 Downregulation12351
Vascular Cell Adhesion Molecule-1 Inhibitor12334Downloadable Document
Insulin-releasing12249Downloadable Document
Interleukin-5 downregulation12049
Leishmanicidal11879Downloadable Document
Cardiotonic Agents10610
Cyclin D1 Down-Regulation10679
Interleukin-10 upregulation10524
Interleukin-1 alpha downregulation10242Downloadable Document
Matrix metalloproteinase-1 (MMP-1) inhibitor9959
Angiotensin-Converting Enzyme Inhibitors9954Downloadable Document
Phase II Detoxification Enzyme Inducer9552Downloadable Document
interleukin-13 down-regulation9047
Fertility Agents: Female9018
Angiogenesis Inducing Agents8845
Insulin-Like Growth Factor Inhibition/Downregulation8618Downloadable Document
Anti-Cachexic Agents7926
Cytotoxic7660
Anti-thrombotic7632Downloadable Document
Galactogogue738
NF-E2-Related Factor-2 (Nrf2) Modulator6939
Xanthine oxidase inhibitor6934Downloadable Document
Anti-Proliferative6755Downloadable Document
Cyclooxygenase 1 Inhibitor6548Downloadable Document
Appetite Suppresant6414
Fertility Agents: Male6014
Interferon Gamma Reducer5824
Thermogenic579
STAT3 Inhibitor5331
Osteogenic5212
Quorum Sensing Inhibition4949
Interleukin-12 upregulation4813
Reverse Transcriptase Inhibitors4729Downloadable Document
Enzyme Inhibitors: Pancreatic Lipase4619
Histamine Antagonists4517Downloadable Document
Histamine Antagonists4517Downloadable Document
Laxative426
Chelating Agents4121
Bax/Bcl2 ratio: Increase4032
SIRT1 Activator3923
Glucagon Like Peptide 1 (GLP-1) Down-Regulation356
Antimycobacterial3519Downloadable Document
Cholecystokinin (CCK) Up-regulation345
Interleukin-6 upregulation3211
Antiurolithiatic319
Carcinogens312
Enzyme Activators2918
Bax/Bcl2 Ratio: Decrease2918
Androgen Antagonists255
Detoxifier: Radionuclide Removal255
Natriuretic Agents234
Viral Hemagglutinin Inhibitor2216Downloadable Document
Chymotrypsin Inhibitor212
Hypnotics and Sedatives206
Adenosine deaminase inhibitor207
Neurominidase Inhibitor2019Downloadable Document
Cholecystokinin Releaser202
Anticoagulants1815
Peptide YY (PYY) Up-Regulation164
Antioxidant Effects154
Hepatocyte growth factor (HGF) inhibitor154
Survivin Down-Regulation1513
Antipsychotic Agents152
Protease Inhibitors156
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor144
Teratogens143
Anti-collagenase132
Leukotriene B4 downregulation134
Insulin Receptor Modulator122
Vasopressin Inhibitor122
Dopamine Agents122
Carminative122
Anti-edemic122
VEGFR3 inhibition123
Mucolytic122
Immunomodulatory: T-Cell down-regulation122
Interleukin-1 receptor antagonist112
Mitogen-activated protein kinase inhibitors112
Mitogen-activated protein kinase kinase 4 (MEK4)112
Insulinotrophic117
Glutathione peroxidase 1 (GPx1) inhibitors101
Insulin Antagonists101
Interleukin-13 Up-Regulation101
Interleukin 1 receptor antagonist (IL-1Ra) up-regulation101
Immune Enhancing Properties101
Immunostimulatory: IgA Production Up-Regulation101
Antilipemic Agents101
Intracellular adhesion molecule down-regulation101
Respiratory System Agents101
Drug sparing101
Interleukin-23 Downregulation101
Immunomodulatory: CD23+ Mature Macrophage Down-Regulation101
Alkylating Agents101
STAT3 Activation108
Peptide YY (PYY) Down-regulation101
Interleukin-3 upregulation101
Hormones101
Fatty Acid Oxidation101
Gastric Inhibitory Polypeptide Up-Regulation101
Immunomodulatory: Immunoglobulin G up-regulation101
Diacylglyceride acyltransferase 1 (DGAT1) Inhibition101
PER2 Protein Expression Up-regulation101
Isoprostane Down-Regulation101
Neurotransmitter Uptake Inhibitors101
NOX2 inhibitor101
Oxytocin inducer101
Insulin-mimetic96
Insecticidal84
Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK72
Excitatory Amino Acid Agonists74
Vascular smooth muscle cell (VSMC) inhibitor75
Monoaminergic63
5-Lipoxygenase Inhibitor65
Antacids51
Insulin-Like Growth Factor Enhancer/Upregulation53
Spermicidal Activity51
HIV Fusion Inhibitors54
Extracellular Signal-Regulated Kinases Modulator54
Matrix Metalloproteinase-7 (MMP-7) Inhibitor41
Erythropoietic43
Antithrombotic42
Thrombolytic42
Phase I Detoxification Enzyme Inducer42
Monoamine Oxidase Inhibitors42
SGLT1 inducer42
Anticholinergic42
Ghrelin Up-regulation42
Intracellular adhesion molecule-1 (ICAM-1)43
Vascular Endothelial Growth Factor A Enhancer42
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Upregulation42
Mitochondrial Superoxide Dismutase Upregulation43
Schistosomicides42
Angiotensin II Type 1 Receptor Blockers42
Contraceptive Agents: Male42
Adrenergic beta-Agonists32
Cholinergic Agents32
Matrix metalloproteinase-8 (MMP-8) inhibitor32
Estradiol 3-glucuronide enhancer33
Atrial Natriuretic Factor Modulation32
Quinone Reductase-Inducer32
Chemokine (C-C motif) Ligand 2 (CCL2) Down-Regulation32
Cholinergic Antagonists32
Interleukin-15 downregulation32
Histamine down-regulation32
TRAIL sensitizer32
Survival protein down-regulation32
Cyclin-Dependent Kinase Inhibitor33
Forkhead Transcription Factor Family O (FOXO) Modulator32
Glucose transporter-2 (GLUT2) expression down-regulation32
Steroidogenesis32
Fertility Agents21
JAM3 gene down-regulation21
Hydroperoxidase Inhibitor21
Myosin heavy chain alpha (MHCalpha) reducer21
Neutrophil Activation: Down-Regulation21
P-glycoprotein Inhibitors22
Abortifacient Agents21
Serotonin Agonists21
Antinitrosation21
Gene Protective21
Opioid Endogenous Up-regulation21
Phase I Detoxification Enzyme Inhibitor21
Bronchoconstrictor Agents21
Akt-dependent HO-1 expression up-regulation21
Remyelination21
Thromboxane B2 Inhibitor22
Uncoupling Agents21
Environmental Pollutants21
Glycine Agents21
Progestagenic21
C-Jun N-Terminal Kinases (JNK) Modulator22
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor22
Anesthetics21
Follicle-stimulating hormone receptor (FSHR) up-regulation21
Incretin Modulator21
1-Glutamine Uptake Inhibitor22
Progesterone receptor (PR) up-regulation21
Calcium Desensitizer21
Death receptor up-regulation21
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)22
Ovogenic21
Adenosine Monophosphate (AMP)-Activated Protein Kinase (AMPK) Down-Regulation21
Cicatrizing21
Cyclin-Dependent Kinase Inhibitor: P1622
Enzyme Inhibitors: Maltase Inhibition21
Leukotriene C4 Downregulation22
Muscarinic Agonists21
Immunomodulatory: CD8+ Up-regulation21
Nootropic Agents21
RANTES (CCL5) Inhibitor22
Angiogenesis Modulating Agents21
Coccidiostats21
Vascular Endothelial Growth Factor C Inhibitor21
Antiparkinson Agents21
GSH-Px Up-Regulation21
Histamine Agents21
Human androgen receptor (AR) antagonist22
Noradrenergic21
Adjuvants: Immunologic21
Receptor-Related Orphan Receptor (ROR)-Alpha1 Inhibitor21
Tumor Necrosis Factor (TNF) Alpha Upregulation21
Antidiuretic Agents21
ER beta receptor up-regulation21
Lymphagogue21
Histamine Agonists21
Myorelaxant21
Insecticides21
Arginine Vasopressin (AVP) up-regulation.21
Adrenergic Agents21
Redox Balancer21
Central Nervous System Agents21
Stomachic21
Endothelin-1 Inhibitor21
Peroxisome Proliferators21
Hematologic Agents11
Molecular Probes11
Hypoxia-inducible factor-1 (HIF-1) inhibitor11
Astringents11
Psychedelic11
Breast cancer resistance protein (BCRP) down-regulation11
Sulfonation11
Cryoprotective Agents11
Tyrosinase Inhibition11
Disinfectants11
Zinc-dependent metalloproteinase inhibitor11
Enkephalinase inhibitor11
Lactate Dehydrogenase A Inhibitor11
Maspin (Protease Inhibitor) Up-Regulation11
Hydroxyheptadecatrienoate (HHT) Inhibitor11
IGF-1R expression down-regulation11
P16 Activation11
PPAR-Gamma Up-Regulation11
Anti-cancer11
β-secretase Inhibitor11
Mast Cell Activation Inhibitor11
Hemolytic Agents11
Matrix Metalloproteinase-8 Inhibitor11
Neovasculogenesis11
p300/NF-κB down-regulation11
Superoxide Scavenger11
Chondroprotective11
Cyclin-Dependent Kinase 4 Down-Regulation11
Cytotoxins11
Dopamine Agonists11
Histamine up-regulation11
mTOR/S6K pathway Activator11
Phosphodiesterase Inhibitors11
Akt-SREBP-1 activater11
Antilipolytic11
Glyoxalase 1 inhibitor11
Neuroimmunomodulation11
Interleukin-1 beta upregulation11
Phospholipase D Inhibitors11
17beta-hydroxysteroid dehydrogenase inhibitor11
Calcium/calmodulin dependent protein kinase II inhibitor11
Transient Receptor Potential Melastatin 2 Inhibition11
E-cadherin down-regulation11
Ionophores11
Matrix metalloproteinase-14 (MMP-14) inhibitor11
Herbicides11
Hypomethylating11
Insect Repellents11
Oxidants11
5-HTergic11
Prostaglandin H Synthase-1 (PGHS-1) Inhibits11
Cancerous inhibitor of protein phosphatase 2A inhibitor11
S-phase kinase associated protein 2 inhibition11
Cyclin-dependent kinase inhibitor: P16INK411
Vitamin D Receptor (VDR) Modulator11
Emmenagogue11
IRAK-MAPK Modulator11
Leukotriene D4 antagonist11
Matrix metalloproteinase-17 (MMP-17) inhibitor11
Muscle Relaxants: Central11
Oxytocics11
PI3K/Akt/signaling suppression11
Arginase 1 (Arg1) up-regulation11
5-Hydroxyeicosatetraenoic acid (5-HETE) Inhibitor11
Prostaglandin H Synthase-2 (PGHS-2) Up-Regulation11
Beta-Defensin-2 Up-Regulation11
Carbonyl Reductase 1Inhibitor11
Contraceptive Agents11
Antibiotics: Antifungal11
Endocannabinoid Modulator11
Fatty Acid Synthesis Inhibitors11
Glucose transporter-5 (GLUT5) expression down-regulation11
Human Polymorphonuclear Leukocyte Degranulation Inhibitor11
PKM2 downregulation11
Alpha-hemolysin inhibitor11
Serine Proteinase Inhibitors11
Dipeptidyl-Peptidase IV Inhibitors11
Antifibrinolytic Agents11
Eryptotic11

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