Abstract Title:

Spontaneous remission of a squamous cell carcinoma of the floor of the mouth.

Abstract Source:

J Craniomaxillofac Surg. 2014 Oct ;42(7):1536-9. Epub 2014 May 9. PMID: 24958155

Abstract Author(s):

Alexandre de Andrade Sousa, Rafael Lopes Rena, Guilherme Souza Silva, João Marcos Arantes Soares, José Maria Porcaro-Salles, Laiz Nunes, Ricardo Alves Mesquita, Bruno Correia Jham

Article Affiliation:

Alexandre de Andrade Sousa


Spontaneous remission is a rare, but well recognized event in oncology. Certain tumours, such as melanomas, hypernephromas and neuroblastomas, are known for showing spontaneous regression. Similarly, spontaneous regression of oral lymphomas, as well as oropharyngeal and recurrent tongue carcinomas, has been reported. Here, we present a novel case of a patient with a primary squamous cell carcinoma on the floor of the mouth whose tumour regressed spontaneously in three months, without any treatment. We also review of the literature on the spontaneous remission of oral cancer and discuss possible mechanisms for this phenomenon.

Study Type : Human: Case Report

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