Abstract Title:

From Seeds of Apium graveolens Linn. to a Cerebral Ischemia Medicine: The Long Journey of 3-n-Butylphthalide.

Abstract Source:

J Med Chem. 2020 Jul 16. Epub 2020 Jul 16. PMID: 32672958

Abstract Author(s):

José Marco-Contelles, Yihua Zhang

Article Affiliation:

José Marco-Contelles


3-n-Butylphthalide (NBP) as well as its derivatives and analogues (NBPs), in racemic or enantiomerically pure forms, possess potent and diverse pharmacological properties, and have shown a great potential therapeutic interest for many human conditions, especially for cerebral ischemia. This Perspective outlines the synthesis and therapeutic applications of NBPs.

Study Type : In Vitro Study

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