n/a
Abstract Title:

Curcumin mouthwashes versus chlorhexidine in controlling plaque and gingivitis: a systematic review and meta-analysis.

Abstract Source:

Int J Dent Hyg. 2021 May 20. Epub 2021 May 20. PMID: 34013606

Abstract Author(s):

Sadeq A Al-Maweri, Mohammed Nasser Alhajj, Esraa A Deshisha, Ameera K Alshafei, Azza I Ahmed, Nada O Almudayfi, Sara A Alshammari, Alla Alsharif, Saba Kassim

Article Affiliation:

Sadeq A Al-Maweri

Abstract:

OBJECTIVES: The purpose of the present systematic review and meta-analysis was to assess the available evidence regarding the efficacy of curcumin mouthwashes on plaque and gingivitis.

METHODS: A comprehensive online search of multiple databases (PubMed, Scopus, Web of Science, and Google Scholar) was performed to identify all relevant studies published up to August 2020, using the following keywords: curcumin, turmeric, gingivitis, periodontal health, and plaque control. All clinical trials that compared the efficacy of curcumin mouthwash with chlorhexidine in controlling dental plaque and gingivitis were included. Data were analyzed using Review Manager (RevMan) 5.3 software. The risk of bias was evaluated by two independent reviewers using Cochrane assessment tool.

RESULTS: Six randomized clinical trials (comprising 320 subjects) fulfilled the eligibility criteria. Five studies showed high risk of bias and only one study showed low risk of bias. The pooled data of the six included studies revealed comparable efficacy of curcumin and chlorhexidine in reducing dental plaque (I= 91%; standardized mean difference (SMD): 0.27, 95% CI: -0.53, 1.07, P= 0. 51) and gingival inflammation (I= 40%; SMD: -0.13, 95% CI: -0.35, 0.09, P= 0.24), with no statistically significant differences between the two groups.

CONCLUSION: The results suggest that curcumin mouthwashes have promising anti-plaque and anti-gingivitis properties. Further clinical trials with adequate sample sizes and standardized methodologies are required to discern the efficacy of curcumin mouthwash in reducing plaque and gingivitis.

Study Type : Review

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.