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Abstract Title:

Effects of Moro orange juice (Citrus sinensis (l.) Osbeck) on some metabolic and morphological parameters in obese and diabetic rats.

Abstract Source:

J Sci Food Agric. 2020 Aug 6. Epub 2020 Aug 6. PMID: 32767388

Abstract Author(s):

Maísa Lamounier Magalhães, Raimundo Vicente de Sousa, José Rafael Miranda, Isaac Filipe Moreira Konig, Flademir Wouters, Fernanda Rezende Souza, Sergio Domingos Simão, Allan da Silva Lunguinho, David Lee Nelson, Maria das Graças Cardoso

Article Affiliation:

Maísa Lamounier Magalhães

Abstract:

BACKGROUND: Nutritional intervention with the use of phytochemicals is an important method for the treatment and prevention of a metabolic syndrome. The objective of this study was to chemically characterize Moro orange juice. The influence of juice intake on metabolic parameters of rats that were obese, diabetic or both by means of body mass management after the activation of anthocyanins during refrigerated storage was also assessed.

RESULTS: Juice intake reversed most of the metabolic abnormalities exhibited by obese rats, including reduction of body mass and improvement of the biochemical profile. The loss of body mass by diabetic animals and obese and diabetic animals was not attributed to juice intake, but to type I diabetes mellitus. In these animals, no improvement was observed in the biochemical profile, liver enzymes and glycemia, so this treatment model was deemed unfeasible.

CONCLUSION: The beneficial effects cannot be explained only by the anthocyanin C3G present in the juice, but rather, by the synergism between all the components. Studies in humans are needed to determine whether the ingestion of this orange can be recommended as an effective strategy to prevent or ameliorate complications of obesity.© 2020 Society of Chemical Industry.

Study Type : Animal Study

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