Abstract Title:

Bisphenol A and adverse pregnancy outcomes: a systematic review of the literature.

Abstract Source:

J Matern Fetal Neonatal Med. 2017 Aug 14:1-15. Epub 2017 Aug 14. PMID: 28805116

Abstract Author(s):

Vasilios Pergialiotis, Paraskevi Kotrogianni, Evangelos Christopoulos-Timogiannakis, Diamanto Koutaki, Georgios Daskalakis, Nikolaos Papantoniou

Article Affiliation:

Vasilios Pergialiotis


PURPOSE: Bisphenol A is a chemical compound related to adverse maternal and neonatal outcomes. The purpose of the present systematic review is to summarize current knowledge in the field.

MATERIALS AND METHODS: We systematically searched the Medline (1966-2017), Scopus (2004-2017), Clinicaltrials.gov (2008-2017), Cochrane Central Register of Controlled Trials CENTRAL (1999-2017) databases.

RESULTS: Thirty-five studies were included in the present systematic review. According to our findings BPA has a direct negative impact on maternal, fetal and neonatal outcomes, including birthweight, rates of preterm birth, developmental defects and recurrent miscarriage. Data in the field of preeclampsia and gestational diabetes mellitus remain inconclusive because current research is very limited.

CONCLUSION: BPA exposure during pregnancy can result in significant antenatal pathology; hence, occupational exposure should be at least discouraged during this period. However, cross-sectional studies in the field that would assess the levels of exposure at timely intervals are still lacking, therefore the actual impact of BPA remains unclear.

Study Type : Review

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Sayer Ji
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