Thymoquinone

Name	AC	CK
Oxidative Stress	25	50
Inflammation	15	25
Breast Cancer	12	16
Cancers: All	14	15
Ischemia	7	14
Lipid Peroxidation	7	13
Chemotherapy-Induced Toxicity: Cisplatin	6	12
Colon Cancer	6	9
Pancreatic Cancer	5	9
Kidney Damage	5	8
Lead Poisoning	4	8
Liver Cancer	5	8
Neurodegenerative Diseases	7	8
Glioblastoma	3	7
Lipopolysaccharide-Induced Toxicity	4	7
Parkinson's Disease	5	7
Rheumatoid Arthritis	4	7
Alcohol Toxicity	3	6
Asthma	4	6
Chemically-Induced Liver Damage	3	6
Chemotherapy-Induced Toxicity: Cyclophosphamide	3	6
Diabetes Mellitus: Type 2	4	6
Gastric Cancer	4	6
Liver Injury: Ischemia/reperfusion	3	6
Myocardial Ischemia	3	6
Cervical Cancer	4	5
Colorectal Cancer	4	5
Glioblastoma Multiforme	1	5
Hydrogen Peroxide Induced Toxicity	1	5
Mycobacterium tuberculosis	1	5
Osteoarthritis	1	5
Prostate Cancer	4	5
Sepsis	3	5
Alzheimer's Disease	3	4
Atherosclerosis	2	4
Cardiovascular Diseases	3	4
Chemotherapy and Radiation Toxicity	2	4
Chemotherapy-Induced Toxicity: Gentamicin	2	4
DNA damage	2	4
Diabetic Complications	3	4
Diabetic Nephropathy	2	4
Drug Toxicity: Methotrexate	2	4
Hypercholesterolemia	2	4
Hypertension	2	4
Insulin Resistance	2	4
Kidney Damage: Chemically-Induced	2	4
Breast Cancer: Triple Negative	3	3
Cancer Metastasis	2	3
Gastric Ulcer	2	3
Kidney Diseases	2	3
Multiple Myeloma	2	3
Pain	2	3
Psoriasis	2	3
Traumatic Brain Injury	2	3
Acrylamide-induced toxicity	1	2
Acute lymphoblastic leukemia (ALL)	2	2
Alcohol Addiction	1	2
Alcoholism	1	2
Allergic Rhinitis	1	2
Antibiotic Toxicity	1	2
Arthritis	1	2
Avian Influenza	1	2
Benzo[a]pyrene-induced Toxicity	1	2
Bisphenol Toxicity	1	2
Bisphenol-A Toxicity	1	2
Brain Cancer	2	2
Brain Damage	1	2
Brain Inflammation	2	2
Brain: Oxidative Stress	1	2
Breast Cancer: Chemically-Induced	1	2
Breast Cancer: Prevention	1	2
Cadmium Poisoning	1	2
Cancers: Drug Resistant	2	2
Cancers: Radiation-Induced	1	2
Cardiac Arrhythmias	1	2
Cataract: Radiation-Induced	1	2
Cerebral Ischemia	1	2
Chemotherapy-Induced Toxicity: Doxorubicin	1	2
Chemotherapy-Induced Toxicity: Kidney	1	2
Cholestasis	1	2
Diabetes Mellitus: Type 2: Prevention	1	2
Diabetes: Cognitive Dysfunction	1	2
Diabetes: Kidney Function	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Neuropathies	1	2
Diabetic Neuropathy	1	2
Diesel Exhaust Particle Toxicity	1	2
Drug-Induced Toxicity: Methotrexate	1	2
Endotoxemia	1	2
Epilepsy	1	2
Epilepsy: Drug-Induced	1	2
Escherichia coli Infections	2	2
Esophageal Cancer	1	2
Facial Nerve Diseases	1	2
Facial Paralysis	1	2
Fibrosis: Liver	1	2
Gastric Ulcers	1	2
Gram-Negative Bacterial Infections	2	2
Gram-Positive Bacterial Infections	2	2
HIV Drug-Induced Toxicity	1	2
Heavy Metal Toxicity	1	2
High Cholesterol	1	2
High Fructose Diet	1	2
High Homocysteine	1	2
Hyperbilirubinemia: Hereditary	1	2
Hyperglycemia	1	2
Hyperlipidemia	1	2
Infertility: Male	1	2
Influenza A	1	2
Intestinal Ischemia	1	2
Kidney Damage: Drug-Induced	1	2
Kidney Fibrosis	1	2
Leukemia	2	2
Liver Damage: Aflatoxin-Induced	1	2
Lung Cancer	2	2
Metabolic Diseases	1	2
Morphine Tolerance/Dependence	1	2
Myocardial Infarction	1	2
Myocardial Necrosis	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Obesity	1	2
Oral Cancer	2	2
Osteoporosis	1	2
Osteosarcoma	2	2
Otitis	1	2
Ovarian Cancer	2	2
Pancreatic Cancer: Metastatic	1	2
Pancreatitis	1	2
Periodontitis	1	2
Polycystic Ovary Syndrome	1	2
Prostatic Hyperplasia: Benign	1	2
Pulmonary Fibrosis	1	2
Radiotherapy	1	2
Seizures	1	2
Sodium nitrate toxicity	1	2
Sperm Quality: Low	1	2
Spinal Cord Injuries	1	2
Staphylococcus aureus infection	2	2
Statin-Induced Pathologies	1	2
Triglycerides: Elevated	1	2
Wound Healing	1	2
Acute Myeloid Leukemia	1	1
Advanced Glycation End products (AGE)	1	1
Allergies	1	1
Autoimmune Diseases	1	1
Bacillus subtilis infections	1	1
Bacterial Infections	1	1
Bladder Cancer	1	1
Brain Ischemia	1	1
Cancers: Multi-Drug Resistant	1	1
Candida Albicans	1	1
Candida Glabrata	1	1
Carcinoma: Non-Small-Cell Lung	1	1
Central Nervous System Diseases	1	1
Clostridium Infections	1	1
Denture Stomatitis	1	1
Diabetes	1	1
Diabetes: Reproductive	1	1
Diarrhea: Bacterial	1	1
Dyslipidemias	1	1
Encephalomyelitis	1	1
Glial Cell Tumors	1	1
Head and Neck Cancer	1	1
Hodgkin Lymphoma	1	1
Leukemia: Acute promyelocytic leukemia	1	1
Lewy Body Parkinson Disease	1	1
Liver Damage	1	1
Liver Diseases	1	1
Lower Respiratory Infections	1	1
Lymphoma	1	1
Medulloblastoma	1	1
Memory Disorders	1	1
Nephrolithiasis	1	1
Neuroblastoma	1	1
Opiate Addiction/Withdrawal	1	1
Opioid Tolerance/Dependence	1	1
Pseudomonas aeruginosa	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Thrombosis	1	1

Name	AC	CK
Antioxidants	65	118
Anti-Inflammatory Agents	55	91
Apoptotic	39	59
Antiproliferative	31	42
Neuroprotective Agents	24	42
Renoprotective	21	38
NF-kappaB Inhibitor	21	35
Hepatoprotective	18	32
Tumor Necrosis Factor (TNF) Alpha Inhibitor	14	27
Chemoprotective Agents	13	24
Interleukin-6 Downregulation	12	24
Anti-Apoptotic	10	19
Anti-metastatic	16	19
Chemotherapeutic	13	18
Cell cycle arrest	10	17
Cardioprotective	9	16
Nitric Oxide Inhibitor	7	16
Anticarcinogenic Agents	10	15
Malondialdehyde Down-regulation	7	14
Chemopreventive	9	13
Cyclooxygenase 2 Inhibitors	7	13
Superoxide Dismutase Up-regulation	6	12
Bcl-2 protein down-regulation	6	11
Gastroprotective	6	11
Immunomodulatory	8	11
Tumor Suppressor Protein p53 Upregulation	6	11
Vascular Endothelial Growth Factor Inhibitors	7	11
Anti-Bacterial Agents	5	10
Antineoplastic Agents	6	10
Interleukin-1 beta downregulation	5	9
Radioprotective	4	8
Chemosensitizer	3	7
Hypoglycemic Agents	4	7
P21 Activation	3	7
Anti-Ulcer Agents	3	6
Hypolipidemic	3	6
Telomerase Inhibitor	2	6
Angiogenesis Inhibitors	3	5
Antimicrobial	5	5
Histone deacetylase inhibitor	1	5
Antihypertensive Agents	2	4
Cytoprotective	2	4
Radiosensitizer	3	4
Antinoceceptive	2	3
Antiviral Agents	2	3
Genoprotective	2	3
Interleukin-2 Downregulation	2	3
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	3
Nrf2 activation	2	3
Pancreato Protective Agents	2	3
STAT3 Inhibitor	2	3
5-Lipoxygenase Inhibitor	1	2
Anti-Asthmatic Agents	1	2
Anti-Fibrotic	1	2
Anticonvulsants	1	2
Antifungal Agents	2	2
Antimutagenic Agents	1	2
Catalase Up-Regulation	1	2
Chemotherapeuticm	1	2
Cytotoxic	2	2
Fertility Agents: Male	1	2
GABA Modulators	1	2
Gastrointestinal Agents	2	2
Heme oxygenase-1 up-regulation	1	2
Interferon-gamma (IFN-gamma) inducer	1	2
Interleukin-1 alpha downregulation	1	2
Interleukin-10 downregulation	1	2
MicroRNA modulator	1	2
Neurogenesis	1	2
Prostaglandin PGE2 downregulation	1	2
Vascular Endothelial Growth Factor A Inhibitor	1	2
Vasodilator Agents	1	2
Wnt/β-catenin signaling pathway modulation	1	2
Analgesics	1	1
Anti-Angiogenic	1	1
Anticoagulants	1	1
Antiparasitic Agents	1	1
Autophagy Inhibitors	1	1
Autophagy Up-regulation	1	1
Enzyme Activators	1	1
Interleukin-8 downregulation	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
P38 Mitogen-Activated Protein Kinase Modulator	1	1
Phase II Detoxification Enzyme Inducer	1	1

[+]

Nigella sativa and thymoquinone: A natural blessing for periodontal therapy.Dec 10, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Biomed Pharmacother. 2018 Jun 29 ;106:390-402. Epub 2018 Jun 29. PMID: 29966985

Article Published Date : Jun 28, 2018

Study Type : Review

Additional Links

Substances : Thymoquinone

Diseases : Cancers: All

Pharmacological Actions : Anti-metastatic, Apoptotic, Chemopreventive, MicroRNA modulator, NF-kappaB Inhibitor

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The reviewed reports confirmed the strong anti-cancer efficacy of thymoquinone.Nov 30, 2019

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Pubmed Data : Biochem Pharmacol. 2012 Feb 15 ;83(4):443-51. Epub 2011 Oct 10. PMID: 22005518

Article Published Date : Feb 15, 2012

Study Type : Review

Additional Links

Substances : Thymoquinone

Diseases : Asthma, Diabetes, Encephalomyelitis, Inflammation

Pharmacological Actions : Antioxidants

[+]

Thymoquinone administration into leukemia-bearing mice induced leukemia regression.Mar 20, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2017 Mar 21. Epub 2017 Mar 21. PMID: 28415607

Article Published Date : Mar 20, 2017

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Leukemia

Pharmacological Actions : Antiproliferative

Additional Keywords : Disease Regression, Hypomethylation

[+]

Thymoquinone and cisplatin appear to be an active therapeutic combination in lung cancer.Jun 30, 2010

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Pubmed Data : J Food Biochem. 2020 Mar 24:e13216. Epub 2020 Mar 24. PMID: 32212163

Article Published Date : Mar 23, 2020

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Allergies, IgE-Mediated Hypersensitivity

Pharmacological Actions : Anti-Allergic Agents, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation.Mar 31, 2019

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Pubmed Data : J Food Biochem. 2019 Apr ;43(4):e12793. Epub 2019 Jan 29. PMID: 31353586

Article Published Date : Mar 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Kidney Cancer

Pharmacological Actions : Antiproliferative

[+]

Thymoquinone augments cyclophosphamide-mediated inhibition of cell proliferation in breast cancer cells.Apr 28, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asian Pac J Cancer Prev. 2019 Apr 29 ;20(4):1153-1160. Epub 2019 Apr 29. PMID: 31030489

Article Published Date : Apr 28, 2019

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Natural Substance/Drug Synergy

[+]

Click here to read the entire abstract

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Pubmed Data : J Neuroimmunol. 2018 Jul 15 ;320:87-97. Epub 2018 May 4. PMID: 29759145

Article Published Date : Jul 14, 2018

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Alzheimer's Disease, Brain Inflammation , Neurodegenerative Diseases, Parkinson's Disease

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

[+]

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells.Aug 03, 2020

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Pubmed Data : Oncotarget. 2020 Aug 4 ;11(31):2959-2972. Epub 2020 Aug 4. PMID: 32821342

Thymoquinone inhibits biofilm formation and virulence properties of periodontal bacteria. Jun 30, 2020

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Pubmed Data : Arch Oral Biol. 2020 Jul ;115:104744. Epub 2020 May 7. PMID: 32416351

Article Published Date : Jun 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Periodontitis, Porphyromonas gingivalis

Pharmacological Actions : Anti-Bacterial Agents

[+]

Thymoquinone inhibits bone metastasis of breast cancer cells.Dec 31, 2017

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Pubmed Data : Anticancer Agents Med Chem. 2019 Jan 24. Epub 2019 Jan 24. PMID: 30678630

Article Published Date : Jan 23, 2019

Study Type : In Vitro Study

Additional Links

Substances : Nigella sativa (aka Black Seed), Thymoquinone

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Thymoquinone is a potent inducer of apoptosis in primary effusion lymphoma cells via release of ROS.Apr 14, 2011

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Pubmed Data : Free Radic Biol Med. 2011 Apr 15 ;50(8):978-87. Epub 2011 Jan 4. PMID: 21215312

Article Published Date : Apr 14, 2011

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Lymphoma

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

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Pubmed Data : J Biosci. 2017 Dec ;42(4):547-554. PMID: 29229873

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Pubmed Data : Curr Pharm Biotechnol. 2018 Nov 13. Epub 2018 Nov 13. PMID: 30421672

Article Published Date : Nov 12, 2018

Study Type : Review

Additional Links

Substances : Thymoquinone

Diseases : Asthma, Cancers: All, Colitis, Diabetes Mellitus: Type 2

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Thymoquinone suppresses growth and invasion and induces apoptosis of glial tumor cells.Jul 22, 2016

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Pubmed Data : Biomed Pharmacother. 2016 Jul 23 ;83:635-640. Epub 2016 Jul 23. PMID: 27459120

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2018 Aug 3 ;8(1):11674. Epub 2018 Aug 3. PMID: 30076320

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Pubmed Data : Mutat Res. 2011 Jan 10 ;706(1-2):28-35. Epub 2010 Oct 30. PMID: 21040738

Article Published Date : Jan 09, 2011

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

Thymoquinone was also found to suppress metastasis through activation of JNK and p38.Apr 04, 2016

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Pubmed Data : Environ Toxicol. 2016 Apr 5. Epub 2016 Apr 5. PMID: 27060453

Article Published Date : Apr 04, 2016

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Colon Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, NF-kappaB Inhibitor

[+]

Click here to read the entire abstract

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Pubmed Data : Int J Nanomedicine. 2020 ;15:8059-8074. Epub 2020 Oct 20. PMID: 33116518

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Malignant Melanoma

Pharmacological Actions : Antineoplastic Agents, Apoptotic

[+]

Thymoquinone-loaded polymeric films and hydrogels for bacterial disinfection and wound healing. Sep 27, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomedicines. 2020 Sep 28 ;8(10). Epub 2020 Sep 28. PMID: 32998437

Article Published Date : Sep 27, 2020

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Wound Healing

Pharmacological Actions : Anti-Bacterial Agents

[+]

Thyomquinone may be a potential agent for ovarian cancer.Dec 31, 2015

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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2016 ;62(6):97-101. Epub 2016 May 30. PMID: 27262811

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Ovarian Cancer

Pharmacological Actions : Apoptotic

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View the Evidence: 434 Abstracts with Thymoquinone Research

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Nigella sativa and thymoquinone: A natural blessing for periodontal therapy.Dec 10, 2020

Nigella sativa essential oil and its bioactive compounds as resistance modifiers against Staphylococcus aureus.Jan 22, 2019

Nigella sativa or thymoquinone could represent an effective strategy against Alzheimer's disease.Dec 31, 2017

Nigella sativa: reduces the risk of various maladies.Jul 31, 2010

Potential protective roles of phytochemicals on glutamate-induced neurotoxicity.Aug 31, 2020

Protective effects of thymoquinon on pulmonary disorders in experimental studies.Sep 30, 2018

Regressions of breast carcinoma syngraft following treatment with piperine in combination with thymoquinone.Jul 02, 2017

Review on molecular and therapeutic potential of thymoquinone in cancer.Dec 31, 2009

Targeting inflammatory mediators: An anticancer mechanism of thymoquinone action.Oct 10, 2019

The combination of temozolomide and thymoquinone may emerge as a promising strategy for the successful treatment of glioblastoma multiforme.Jun 30, 2018

The effects of thymoquinone on viability, and anti-apoptotic factors in prostate cancer cells.Jul 31, 2019

The efficacy of N. sativa to postpone progression in chronic liver diseases should be considered as preventive medicine in patients with hepatic disorders.Nov 30, 2014

The evidence presented in this paper appears to be supporting the hypothesis that Nigella sativa can enhance learning and memory.Dec 31, 2015

The findings of this study suggest that thymoquinone may prevent neurotoxicity and arsenic trioxide-induced apoptosis and cytotoxicity.Sep 18, 2018

The fungicidal effects of thymoquinone could induce oxidative stress in candida glabrata.Dec 31, 2016

The present review article highlights the anticancer perspectives of thymoquinone in human by various pathways.Jun 28, 2018

The reviewed reports confirmed the strong anti-cancer efficacy of thymoquinone.Nov 30, 2019

These findings confirm that thymoquinone has the potential to be used to combat L. monocytogenes infection.Dec 31, 2018

These findings propose that thymoquinone may regulate self-renewal and immunomodulatory potential of mesenchymal stem cells.May 31, 2018

These findings suggest that thymoquinone is a potential therapeutic agent against prostate cancer.Oct 01, 2017

These findings suggest Thymoquinone as a potential small molecular inhibitor of cancer growth and metastasis.Aug 13, 2015

These results provide support for the beneficial use of TQ as a therapeutic and chemopreventive agent against liver cancer.Jun 30, 2015

These results suggest the potential of thymoquinone lipospheres in the management of psoriasis.Jun 21, 2017

This delivers an outline of thymoquinone role in cancer inhibition and prevention of cancer.Apr 14, 2020

This is the first detailed report on anti-MRSA activity of thymoquinone.Feb 29, 2016

This points to potential antioxidative qualities of thymoquinone.Aug 31, 2007

This review concentrated on four properties of thymoquinone: hepatoprotective, anti-inflammatory, antioxidant and anti-cancer effects.Nov 30, 2014

This review describes protective role and related mechanism of thymoquinone against liver injuries.Feb 19, 2018

This review provides summery of scientific research regarding the gastrointestinal effect of N. sativa and its main constituent, thymoquinone.Dec 31, 2015

This review suggests that the neuroprotective effects of thymoquinone are associated with the antioxidant and anti-inflammatory activities.Mar 31, 2018

This review summarizes the in vitro and in vivo possible mechanisms of thymoquinone anticancer effect.Dec 31, 2014

This review summarizes the potential roles of thymoquinone in the prevention and treatment of liver cancer.Dec 31, 2018

This review the prevention of and protection of renal injury by thymoquinone.Aug 31, 2009

This study demonstrates a potential role for thymoquinone in ameliorating asthma.May 26, 2016

THQ has minimal effect on normal blood coagulation and can effectively reverse sepsis-mediated and cancer-mediated thrombosis.Dec 31, 2015

Thymoquinone (from the plant Nigella Sativa) has been studied since the 60s for its antioxidant, anti-inflammatory and anticancer effects. Feb 15, 2012

Thymoquinone administration into leukemia-bearing mice induced leukemia regression.Mar 20, 2017

Thymoquinone and cisplatin appear to be an active therapeutic combination in lung cancer.Jun 30, 2010

Thymoquinone and cisplatin had comparable antitumoric effects on SK-OV-3 cells.Jul 06, 2017

Thymoquinone and cisplatin, alone or in combination can inhibit cell viability and induce apoptosis in oral squamous cell carcinoma cells.Oct 12, 2017

Thymoquinone and difluoromethylornithine (DFMO) synergistically induce apoptosis of human acute T lymphoblastic leukemiaDec 31, 2019

Thymoquinone and genistein can be good options as potential phytochemotherapeutics against thyroid cancer cells.Dec 31, 2017

Thymoquinone and its improved bioavailability product may be an effective antiproliferative agent for treatment of liver cancer.Dec 31, 2017

Thymoquinone and miR-34a have synergistic effects against breast cancer cell migration and invasion.Mar 27, 2017

Thymoquinone and paclitaxel combined act in synergy against triple negative breast cancer cells.Oct 25, 2015

Thymoquinone attenuates IgE-mediated allergic response.Mar 23, 2020

Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation.Mar 31, 2019

Thymoquinone augments cyclophosphamide-mediated inhibition of cell proliferation in breast cancer cells.Apr 28, 2019

Thymoquinone bears outstanding potential against hepatocellular carcinoma.Apr 15, 2019

Thymoquinone can also regulate IRF-3, one of the inflammatory transcription factors, providing a novel insight into its anti-inflammatory activities.May 02, 2018

Thymoquinone can improve the therapeutic efficacy and safety profile of the main course cancer therapies.Dec 31, 2016

Thymoquinone challenges UHRF1 to commit auto-ubiquitination: a key event for apoptosis induction in cancer cells.Jun 18, 2018

Thymoquinone could induce apoptosis in MCF-7 cells through up-regulation of P53 expression.Dec 31, 2015

Thymoquinone enhances paclitaxel anti-breast cancer activity.Jan 19, 2020

Thymoquinone exhibits anticancer activity via numerous mechanisms of actionJul 31, 2017

Thymoquinone exhibits anticancer activity via numerous mechanisms of action.Apr 17, 2017

Thymoquinone has a role in treating opioid withdrawal syndrome.Nov 30, 2014

Thymoquinone has an anti-inflammatory effect on pancreatic ductal adenocarcinoma.Jul 31, 2009

Thymoquinone has potential for the development of novel therapies against pancreatic cancer.Apr 30, 2010

Thymoquinone has pro-apoptotic and anti-metastatic effects on stomach cancer cell line.Feb 05, 2019

Thymoquinone increased the effectiveness of the chemotherapeutic reagent topotecan by inhibiting proliferation and lowering toxicity.Feb 04, 2016

Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines.Jul 14, 2018

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells.Aug 03, 2020

Thymoquinone induces apoptosis in B16-F10 melanoma cells.Mar 02, 2018

Thymoquinone induces apoptosis in bladder cancer cells.Jul 01, 2018

Thymoquinone induces apoptosis in oral cancer cells through p38β inhibition.Dec 31, 2012

Thymoquinone induces apoptosis of human renal carcinoma Caki-1 cells.Mar 08, 2020

Thymoquinone induces both extrinsic and intrinsic pathways of apoptosis in medulloblastoma cells.Apr 14, 2016

Thymoquinone induces mitochondria-mediated apoptosis in acute lymphoblastic leukaemia in vitro.Dec 31, 2012

Thymoquinone inhibited epithelial-mesenchymal transition in bladder cancer cells via modulation of mTOR signalling.Dec 29, 2015

Thymoquinone inhibits angiotensin II-induced proliferation and migration of vascular smooth muscle cells.Apr 10, 2016

Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells.Dec 31, 2012

View the Evidence:
434 Abstracts with Thymoquinone Research

Thymoquinone induces apoptosis of human renal carcinoma Caki-1 cells.Mar 08, 2020