Sesame Seeds

Name	AC	CK
Oxidative Stress	30	91
Hypertension	9	67
Inflammation	12	36
Diabetes: Cardiovascular Illness	3	30
Lipid Peroxidation	14	25
Diabetes Mellitus: Type 2	3	21
Cardiovascular Diseases	2	20
Osteoarthritis: Knee	2	20
Atherosclerosis	3	14
Cholesterol: LDL/HDL ratio	2	12
Endothelial Dysfunction	2	12
Rheumatoid Arthritis	2	12
Triglycerides: Elevated	2	12
Dyslipidemias	2	11
A1C	1	10
Athletic Performance	1	10
Blood Viscosity: Elevated	1	10
C-Reactive Protein	1	10
Chronic Fatigue Syndrome	1	10
Chronic Pain	1	10
Diabetes: Glycation/A1C	1	10
Fatigue	1	10
Gingivitis	1	10
Hyperviscosity Syndrome	1	10
Infant Problems	1	10
Kidney Failure	1	10
Muscle Damage: Exercise-Induced	1	10
Osteoarthritis	1	10
Periodontal Diseases	1	10
Prehypertension	1	10
Sleep Disorders	1	10
Lipopolysaccharide-Induced Toxicity	5	9
Chemically-Induced Liver Damage	3	6
Chemotherapy and Radiation Toxicity	3	6
Hyperlipidemia	2	6
Kidney Damage	3	6
Liver Damage	3	6
Arthritis	2	4
Cerebral Ischemia	2	4
Cognitive Decline/Dysfunction	2	4
Colon Cancer	3	4
DNA damage	3	4
Diabetes: Cognitive Dysfunction	2	4
Endotoxemia	2	4
Huntington Disease	2	4
Inflammatory Bowel Diseases	2	4
Memory Disorders	2	4
Sepsis	2	4
Brain: Oxidative Stress	2	3
Chemotherapy-Induced Toxicity: Doxorubicin	2	3
Liver Cancer	3	3
Radiation Induced Illness	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Aluminum Toxicity	1	2
Antibiotic Toxicity	1	2
Arteriosclerosis	1	2
Blood Pressure: High	1	2
Blood-Brain-Barrier Disorders	1	2
Brain Damage	1	2
Brain Inflammation	1	2
Breast Cancer: Conventional Treatment	1	2
Candida Albicans	2	2
Candida Infection	1	2
Cataract	1	2
Colitis	1	2
Depression	1	2
Diabetic Neuropathies	1	2
Enterocolitis: Necrotiziing	1	2
Epilepsy	1	2
Gastric Ulcer	1	2
HDL: Low	1	2
High Fat Diet	1	2
High Fructose Diet	1	2
Hypercholesterolemia	1	2
Intima Media Thickening	1	2
Kidney Damage: Antibiotic-Induced	1	2
Kidney Damage: Chemically-Induced	1	2
Lung Cancer	2	2
Lung Infection	1	2
Lung Injury: Acute	1	2
Memory Impairment: Hormone Deficiency Induced	1	2
Menopausal Syndrome	1	2
Multiple Sclerosis	1	2
Myocardial Infarction	1	2
Myocardial Infarction: Prevention	1	2
Neuropathic Pain	1	2
Obesity	1	2
Pancreatitis	1	2
Parkinson's Disease	1	2
Pesticide Toxicity: Cypermethrin	1	2
Postmenopausal Disorders: Memory Impairment	1	2
Radiation Disaster Associated Toxicity	1	2
Respiratory Infections	1	2
Sinusoidal obstruction syndrome	1	2
Skin Cancer	1	2
Skin Diseases: Photo-Aging	2	2
Staphylococcus aureus infection	1	2
Streptococcus pneumoniae infection	1	2
Stroke: Ischemic	1	2
Thrombosis	1	2
Wound Healing	1	2
Alzheimer's Disease	1	1
Anemia	1	1
Breast Cancer	1	1
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	1
Freckles	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Leukemia	1	1
Liver Cancer: Prevention	1	1
Malignant Melanoma	1	1
Melanoma	1	1
Melasma	1	1
Multiple Myeloma	1	1
Neurodegenerative Diseases	1	1
Osteoporosis	1	1
Pancreatic Cancer	1	1
Progesterone: Low	1	1
Prostate Cancer	1	1
Radiation Induced Illness: Immune Suppression	1	1
Sunburn	1	1
Testicular Cancer	1	1
Tuberculosis: Drug Resistant	1	1
Ultraviolet Radiation Induced Damage	1	1
Epstein-Barr Virus Infections	1	0
Wound Healing: Delayed	1	0

Name	AC	CK
Antioxidants	49	132
Antihypertensive Agents	4	42
Malondialdehyde Down-regulation	4	32
Interleukin-6 Downregulation	7	29
Tumor Necrosis Factor (TNF) Alpha Inhibitor	11	29
Anti-Inflammatory Agents	14	26
Cardioprotective	5	26
Neuroprotective Agents	12	23
Hypoglycemic Agents	2	20
Radioprotective	7	12
Analgesics	1	10
Anti Inflammatory	1	10
Apoptotic	8	10
Hypolipidemic	1	10
Intracellular adhesion molecule down-regulation	1	10
anti-inflammatory	1	10
Glutathione Upregulation	4	8
Renoprotective	4	8
Interleukin-1 beta downregulation	4	7
Anti-atherogenic	2	6
Cyclooxygenase 2 Inhibitors	4	6
Gastroprotective	3	6
Hepatoprotective	3	6
Chemopreventive	3	5
NF-kappaB Inhibitor	4	5
Anti-Apoptotic	2	4
Chemoprotective Agents	3	4
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	4
Anti-Adipogenic	2	3
Antiproliferative	3	3
Cell cycle arrest	3	3
Nitric Oxide Inhibitor	2	3
Nrf2 activation	2	3
Prostaglandin PGE2 downregulation	2	3
Superoxide Dismutase Up-regulation	2	3
Anti-thrombotic	1	2
Anticarcinogenic Agents	1	2
Anticholesteremic Agents	1	2
Anticonvulsants	1	2
Antidepressive Agents	1	2
Antifungal Agents	2	2
Antimicrobial	1	2
Antinitrosation	1	2
Bcl-2 protein down-regulation	1	2
Brain-derived neurotrophic factor modulator	1	2
Caspase-3 Inhibition	1	2
Catalase Up-Regulation	1	2
Chondroprotective	1	2
Cyclooxygenase Inhibitors	1	2
Enzyme Inhibitors	1	2
Immunomodulatory	1	2
Interferon Gamma Reducer	1	2
Interleukin-1 alpha downregulation	1	2
Interleukin-10 upregulation	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Mitochondrial Superoxide Dismutase Upregulation	1	2
Anti-Angiogenic	1	1
Anti-Bacterial Agents	1	1
Anti-Proliferative	1	1
Antineoplastic Agents	1	1
Autophagy Inhibitors	1	1
Lipoxygenase Inhibitors	1	1
Photoprotective	1	1
STAT3 Inhibitor	1	1
Secretagogue	1	1
Steroidogenesis	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Tyrosinase Inhibition	1	1

[+]

Sesame consumption can reduce systolic and diastolic blood pressure.Jul 31, 2017

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Pubmed Data : J Sci Food Agric. 2017 Aug ;97(10):3087-3094. Epub 2017 May 12. PMID: 28387047

Article Published Date : Jul 31, 2017

Study Type : Meta Analysis, Review

Additional Links

Substances : Sesame Seeds

Diseases : Hypertension

Pharmacological Actions : Antihypertensive Agents

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Application of massage with sesame oil as a complementary method is effective in reducing the pain severity of patients with CIP.Apr 30, 2019

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Pubmed Data : Complement Ther Clin Pract. 2019 May ;35:78-85. Epub 2019 Feb 2. PMID: 31003690

Sesame lignans with vitamin E supplementation could safely alleviate daily fatigue and oxidative stress.Mar 24, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Med Food. 2006 Fall;9(3):408-12. PMID: 17004907

Article Published Date : Sep 01, 2006

Study Type : Human Study

Additional Links

Substances : Sesame Seed Oil

Diseases : Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2

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Topical sesame oil was non-inferior to diclofenac gel on the reduction of the knee osteoarthritis pain.Nov 30, 2019

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Pubmed Data : Complement Ther Med. 2019 Dec ;47:102183. Epub 2019 Aug 22. PMID: 31780006

Article Published Date : Nov 30, 2019

Study Type : Human Study

Additional Links

Substances : Sesame oil: topical, Sesame Seed Oil

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Diclofenac

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White sesame seed oil may play an important role in GLU regulation and against deleterious effects of diabetes in humans with type 2 diabetes.Feb 28, 2019

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Pubmed Data : J Am Coll Nutr. 2019 Mar-Apr;38(3):235-246. Epub 2018 Sep 27. PMID: 30260748

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Pubmed Data : J Agric Food Chem. 2019 Jun 5 ;67(22):6190-6201. Epub 2019 May 28. PMID: 31117496

Article Published Date : Jun 04, 2019

Study Type : Animal Study

Additional Links

Substances : Sesamol

Diseases : High Fat Diet, Neurodegenerative Diseases

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Gut-brain Axis

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Bisphenol A-induced oxidative damage in the hepatic and cardiac tissues of rats: The modulatory role of sesame lignans.Dec 31, 2019

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Pubmed Data : Exp Ther Med. 2020 Jan ;19(1):33-44. Epub 2019 Nov 13. PMID: 31853270

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Pubmed Data : Shock. 2006 May ;25(5):528-32. PMID: 16680019

Article Published Date : May 01, 2006

Study Type : Animal Study

Additional Links

Substances : Sesamol

Diseases : Lipid Peroxidation, Liver Damage, Oxidative Stress

Pharmacological Actions : Hepatoprotective

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Sesamol exerts ameliorative effects in the experimental model of epilepsy.Jan 31, 2014

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Pubmed Data : Environ Toxicol Pharmacol. 2009 Sep ;28(2):192-7. Epub 2009 Apr 11. PMID: 21784002

Article Published Date : Sep 01, 2009

Study Type : Animal Study

Additional Links

Substances : Sesamol

Diseases : Oxidative Stress, Radiation Disaster Associated Toxicity

Pharmacological Actions : Antioxidants, Radioprotective

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Sesamol has significant cardioprotection against doxorubicin induced cardiomyopathy.Dec 31, 2012

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Pubmed Data : J Ethnopharmacol. 2011 Jan 27 ;133(2):608-12. Epub 2010 Oct 28. PMID: 21035533

Article Published Date : Jan 27, 2011

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Pubmed Data : Chem Biol Interact. 2018 Dec 25 ;296:171-178. Epub 2018 Sep 24. PMID: 30261164

Article Published Date : Dec 24, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Sesamol

Diseases : Lipopolysaccharide-Induced Toxicity, Mitochondrial Dysfunction

Pharmacological Actions : Anti-Apoptotic

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Tradit Complement Med. 2018 Jul ;8(3):377-386. Epub 2017 Jul 5. PMID: 29992108

Additional Keywords : Plant Extracts

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Review: Sesamol has significant antioxidant properties. Jul 01, 2009

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Pubmed Data : Med Chem. 2009 Jul ;5(4):367-71. PMID: 19689394

Article Published Date : Jul 01, 2009

Study Type : Review

Additional Links

Substances : Sesamol

Diseases : Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antioxidants

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Role of L-type amino acid transporter 1 for the selective cytotoxicity of sesamol in human melanoma cells.Oct 26, 2019

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Pubmed Data : Molecules. 2019 Oct 27 ;24(21). Epub 2019 Oct 27. PMID: 31717859

Article Published Date : Oct 26, 2019

Study Type : In Vitro Study

Additional Links

Substances : Sesamol

Diseases : Melanoma

Pharmacological Actions : Antiproliferative

Additional Keywords : Selective Cytotoxicity

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Sesame has a broad range of therapeutic applications in supporting health. Jan 01, 2007

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Pubmed Data : Crit Rev Food Sci Nutr. 2007;47(7):651-73. PMID: 17943496

Article Published Date : Jan 01, 2007

Study Type : Review

Additional Links

Substances : Sesame Seeds

[+]

Sesame seed extract has antimicrobial properties. Jan 01, 2007

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Pubmed Data : Afr J Tradit Complement Altern Med. 2007 ;4(4):427-33. Epub 2007 Jun 10. PMID: 20161911

Article Published Date : Jan 01, 2007

Study Type : In Vitro Study

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Med J Islam Repub Iran. 2018 ;32:98. Epub 2018 Oct 10. PMID: 30788333

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Sesame Seed Oil , Sesamol

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Sesame showed relevant effects on oxidative stress, suggesting it could increase the antioxidant capacity.Mar 31, 2016

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Pubmed Data : J Med Food. 2016 Apr ;19(4):337-45. PMID: 27074618

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Pubmed Data : Biol Pharm Bull. 2013 ;36(10):1540-8. PMID: 24088253

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Pubmed Data : Biochem Biophys Res Commun. 2016 Jan 1 ;469(1):49-54. Epub 2015 Nov 23. PMID: 26616060

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Pubmed Data : Arch Dermatol Res. 2010 Dec ;302(10):733-44. Epub 2010 Aug 10. PMID: 20697726

Article Published Date : Dec 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Sesamol

Diseases : DNA damage, Lipid Peroxidation, Oxidative Stress, Skin Diseases: Photo-Aging

Pharmacological Actions : Antioxidants, Apoptotic, Superoxide Dismutase Up-regulation

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Sesamol represents a new skin-whitening agent for use in cosmetics.Sep 30, 2015

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View the Evidence: 139 Abstracts with Sesame Seeds Research

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Sesame consumption can reduce systolic and diastolic blood pressure.Jul 31, 2017

"Sesame oil exhibits synergistic effect with anti-diabetic medication in patients with type 2 diabetes mellitus."Jun 01, 2011

A blend of sesame oil and rice bran oil as cooking oil showed a significant antihypertensive and lipid-lowering action.Feb 29, 2016

A dietary mixture of sesame, pumpkin and flax seed added to a habitual diet lowered triglyceride and CRP, TNF-alpha, IL-6 levelsDec 31, 2013

Antihypertensive and antioxidant effects of dietary black sesame meal in pre-hypertensive humans.Dec 31, 2010

Application of massage with sesame oil as a complementary method is effective in reducing the pain severity of patients with CIP.Apr 30, 2019

Effect of sesame oil, ozonated sesame oil, and chlorhexidine mouthwash on oral health status of adolescents.Sep 30, 2019

Massage with sesame seed oil significantly improves growth in infants. Dec 01, 2000

Massage with topical sesame oil was associated with significant reduction in pain severity of patients with limbs trauma.May 31, 2017

Oil pulling with sesame seed oil has a beneficial effect on patients with gingivitis. Jan 01, 2009

Oil pulling with sesame seed oil significantly reduces Steptococcus mutans in plaque and saliva of children. Mar 01, 2008

Sesame consumption may reduce muscle damage and oxidative stress while improving the aerobic capacity in soccer players.Dec 31, 2016

Sesame lignans with vitamin E supplementation could safely alleviate daily fatigue and oxidative stress.Mar 24, 2015

Sesame oil and vitamin E co-administration may improve cardiometabolic risk factors in patients with metabolic syndrome.Sep 30, 2019

Sesame oil consumption exerts a beneficial effect on endothelial function in hypertensive men. Jan 24, 2012

Sesame oil Shirodhara may be a safe potential treatment to improve sleep quality and QOL in persons with sleep problems.Dec 31, 2015

Sesame seed is a natural and safe substance that may have beneficial effects in patients with knee osteoarthritis.Dec 31, 2014

Sesame seed oil has a beneficial effect in hypertensive patients on either diuretics or beta-blockers. Mar 01, 2006

Sesame seed paste reduces cardiovascular disease risk factors in type 2 diabetics. Oct 31, 2013

Sesame seed supplementation compares favorably to drug therapy on clinical signs and symptoms in patients with knee osteoarthritis.Sep 30, 2013

Sesamin (a compound found within sesame seeds) and Schisandra extract improves blood fluidity. Jan 27, 2008

Sesamin exhibited a protective effect on cardiovascular risk factors in patients with rheumatoid arthritis.Apr 30, 2016

The substitution of sesame seed oil as the sole edible oil lowers blood pressure and glucose in hypertensive diabetics. Sep 01, 2006

Topical sesame oil was non-inferior to diclofenac gel on the reduction of the knee osteoarthritis pain.Nov 30, 2019

White sesame seed oil may play an important role in GLU regulation and against deleterious effects of diabetes in humans with type 2 diabetes.Feb 28, 2019

"Sesame Oil Accelerates Healing of 2,4,6-Trinitrobenzenesulfonic Acid-Induced Acute Colitis by Attenuating Inflammation and Fibrosis."Dec 13, 2012

A sesame oil enriched diet could be an effective nonpharmacological treatment for atherosclerosis by controlling inflammation and regulating lipid metabolism.Dec 31, 2014

ApoE-dependent protective effects of sesamol on high-fat diet-induced behavioral disorders.Jun 04, 2019

Bisphenol A-induced oxidative damage in the hepatic and cardiac tissues of rats: The modulatory role of sesame lignans.Dec 31, 2019

Black sesame seed pigment has antioxidant/antinitrosating properties.Mar 23, 2012

Both free and encapsulated sesamol demonstrated inhibition of tumor progression by inducing skin cell apoptosis via bcl-2/bax mediated pathway.Aug 18, 2016

Dietary sesame oil protect against cerebral ischemia in rat brain. Oct 12, 2006

Elevated levels of cholesterol and triacylglycerol were significantly reversed by the sesamol.May 31, 2013

Oral supplementation of sesamol and sesamin beneficially modulated the inflammatory and oxidative stress markers.Feb 28, 2017

Sesame is a hypocholesteraemic and antioxidant dietary component.Jun 01, 2008

Sesame lignans suppress age-related cognitive decline in senescence-accelerated mice.Jul 11, 2019

Sesame oil attenuates renal oxidative stress induced by a high fat diet.May 31, 2019

Sesame oil protects against cypermethrin-induced toxicity to rat liver and kidney.Jan 01, 2012

Sesame oil therapy protects mice from developing experimental autoimmune encephalomyelitis by reducing IFN-gamma secretion.Apr 28, 2011

Sesame Seed Oil attenuates antibiotic-induced kidney damageFeb 01, 2001

Sesame seed oil attenuates oxidative stress and endotoxemia in rats. Mar 01, 2008

Sesame seed oil may inhibit atherosclerosis lesion formation. Dec 01, 2006

Sesame seed oil reduces oxidative stress after the onset of sepsis in rats. Dec 01, 2004

Sesame seed powder contains antihypertensive ACE-inhibiting peptides.May 01, 2006

Sesame seeds have anti-thrombotic properties.Sep 01, 2011

Sesame seeds should be avoided during Tamoxifen therapy. Jun 01, 2007

Sesamin may prevent the development of atherosclerosis and inflammatory responsesSep 01, 2010

Sesamol alleviates obesity-related hepatic steatosis via activating hepatic PKA pathway.Jan 25, 2020

Sesamol ameliorates diet-induced obesity in C57BL/6J mice.Dec 23, 2016

Sesamol ameliorates high-fat and high-fructose induced cognitive defects.Jan 18, 2017

Sesamol as a single prophylactic dose protects hematopoietic and gastrointestinal systems against γ-radiation-induced injury in mice.Dec 31, 2014

Sesamol attenuates diabetes-associated cognitive decline in rats. Mar 01, 2008

Sesamol attenuates diclofenac-induced acute gastric mucosal injury.Oct 01, 2008

Sesamol attenuates experimentally induced Huntington-like changes in an animal model. Jan 01, 2009

Sesamol attenuates experimentally induced myocardial infarction. Jan 01, 2011

Sesamol attenuates lipopolysaccharide induced hypotension by regulating the circulating inflammatory response.Dec 31, 2014

Sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome.Jun 17, 2011

Sesamol attenuates oxidative stress-mediated experimental acute pancreatitis in rats.Mar 31, 2012

Sesamol attenuates the renoinflammatory cascade in experimental model of diabetic nephropathy. Jul 22, 2009

sesamol could be a potential neuroprotective agent during aging process due to its beneficial effects on liver-brain axis.Nov 13, 2018

Sesamol delays mortality and attenuates liver injury. May 01, 2006

Sesamol exerts ameliorative effects in the experimental model of epilepsy.Jan 31, 2014

Sesamol exhibits anti-depressant properties.Apr 01, 2011

Sesamol has neuroprotective properties. Jun 01, 2011

Sesamol has protective effects on mucosal in Inflammatory bowel disease.Dec 31, 2013

Sesamol has radioprotective properties. Sep 01, 2009

Sesamol has significant cardioprotection against doxorubicin induced cardiomyopathy.Dec 31, 2012

Sesamol has strong potential to protect hematopoietic system by lowering radiation induced DNA damages.Aug 01, 2017

Sesamol has therapeutic value in ovariectomy-induced pathophysiological changes.Sep 26, 2012

Sesamol has wound healing properties.Jan 27, 2011

Sesamol improves blood-brain-barrier function in diabetic rats. Jul 01, 2009

Sesame Seeds

View the Evidence:
139 Abstracts with Sesame Seeds Research