Salvia miltiorrhiza

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2 Diseases Researched for Salvia miltiorrhiza
NameACCKFocus
Chemotherapy-Induced Toxicity: 5-fluorouracil 12Locked
Oral Mucositis12Locked
1 Pharmacological Actions Researched for Salvia miltiorrhiza
NameACCKFocus
Chemoprotective Agents12Locked

View the Evidence:
37 Abstracts with Salvia miltiorrhiza Research

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A methanol extract of Salvia miltiorrhiza Bunge induced apoptosis in non-small cell lung cancer.Mar 21, 2017

Pubmed Data : J Ethnopharmacol. 2017 Mar 22 ;200:107-116. Epub 2017 Jan 12. PMID: 28088493
Article Published Date : Mar 21, 2017
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Apoptotic, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Plant Extracts
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Acute treatment with Salvia miltiorrhiza extract reduced the glycemia rise induced by a bolus of starch.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2015 Oct ;11(Suppl 4):S545-9. PMID: 27013792
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
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Anti-obesity effects of tanshinone I from Salvia miltiorrhiza.Apr 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Apr 27 ;12(5). Epub 2020 Apr 27. PMID: 32349456
Article Published Date : Apr 26, 2020
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Insulin Sensitizers
Additional Keywords : Anti-Obesity Agents
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Anti-osteoporotic effects of Salvia miltiorrhiza Bunge EtOH extract both in ovariectomized and naturally menopausal mouse models.Apr 17, 2020

Pubmed Data : J Ethnopharmacol. 2020 Apr 18 ;258:112874. Epub 2020 Apr 18. PMID: 32311485
Article Published Date : Apr 17, 2020
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
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Combination of probiotics and Salvia miltiorrhiza polysaccharide alleviates hepatic steatosis. Dec 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetes Metab J. 2019 Dec 3. Epub 2019 Dec 3. PMID: 31950772
Article Published Date : Dec 02, 2019
Study Type : Animal Study
Additional Links
Substances : Probiotics, Salvia miltiorrhiza
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
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Cryptotanshinone could be developed as a potential therapeutic agent for the treatment of chronic diabetic wound healing.Nov 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2020 Dec ;58(1):845-853. PMID: 32870741
Article Published Date : Nov 30, 2020
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Diabetes Mellitus: Type 2, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
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Danshensu plus hydroxysafflor yellow A could achieve remarkable synergistic neuroprotective effects on ischemia-reperfusion injury.Dec 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Dec 29 ;8(70):115434-115443. Epub 2017 Dec 15. PMID: 29383171
Article Published Date : Dec 28, 2017
Study Type : Animal Study
Additional Links
Substances : Safflower, Salvia miltiorrhiza
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
Additional Keywords : Natural Substance Synergy
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Pretreatment with Salvia miltiorrhiza polysaccharides protects from lipopolysaccharides/d-Galactosamine-induced liver injury.May 09, 2019

Pubmed Data : J Interferon Cytokine Res. 2019 May 10. Epub 2019 May 10. PMID: 31074668
Article Published Date : May 09, 2019
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
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Salvia miltiorrhiza and ligustrazine is safe and effective in repressing BLM-induced pulmonary fibrosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2018 ;13:36. Epub 2018 Jul 4. PMID: 29997685
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Ligustrazine, Salvia miltiorrhiza
Diseases : Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
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Salvia miltiorrhiza could be used for the prevention and treatment of oral mucositis caused by cancer therapies.May 22, 2017

Pubmed Data : Int J Mol Med. 2017 May 23. Epub 2017 May 23. PMID: 28535007
Article Published Date : May 22, 2017
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Chemotherapy-Induced Toxicity: 5-fluorouracil , Oral Mucositis
Pharmacological Actions : Chemoprotective Agents
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Salvia miltiorrhiza enhances the survival of mesenchymal stem cells under ischemic conditions.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharm Pharmacol. 2018 Sep ;70(9):1228-1241. Epub 2018 Jun 25. PMID: 29943504
Article Published Date : Aug 31, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Stroke: Ischemic
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Mesenchymal Stem Cells
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Salvia miltiorrhiza extract attenuates spinal cord injury.May 20, 2019

Pubmed Data : Phytomedicine. 2019 May 21 ;62:152966. Epub 2019 May 21. PMID: 31132751
Article Published Date : May 20, 2019
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Spinal Cord Injuries
Pharmacological Actions : Neuroprotective Agents
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Salvia miltiorrhiza extracts alleviate airway inflammation.Dec 31, 2018

Pubmed Data : Phytomedicine. 2019 Jan ;52:168-177. Epub 2018 Sep 17. PMID: 30599896
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents
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Salvia miltiorrhiza protects against diabetic nephropathy.Nov 01, 2018

Pubmed Data : Pharmacol Res. 2018 Nov 2. Epub 2018 Nov 2. PMID: 30395946
Article Published Date : Nov 01, 2018
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Diabetic Nephropathy
Pharmacological Actions : Renoprotective, Wnt/β-catenin signaling pathway modulation
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Tanshinones from Salvia miltiorrhiza Bunge revert chemotherapy-induced neuropathic pain and reduce glioblastoma cells malignancy.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:1042-1049. Epub 2018 Jun 19. PMID: 30021339
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Chemotherapy and Radiation Toxicity, Glioblastoma, Neuropathic Pain
Pharmacological Actions : Chemoprotective Agents, Chemotherapeutic
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These results suggested that Salvia miltiorrhiza improved diabetic vascular injury.Apr 21, 2019

Pubmed Data : Food Chem Toxicol. 2019 Apr 22. Epub 2019 Apr 22. PMID: 31022479
Article Published Date : Apr 21, 2019
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Diabetic Complications
Pharmacological Actions : Vasoprotective
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This provided a new insight into the anti-fibrotic mechanism that Salvia Miltiorrhiza could enhance the activities of NK cell to reduce liver fibrosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:762. Epub 2018 Jul 16. PMID: 30061833
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective, Immunostimulatory
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This study presents evidence for the therapeutic effects of Salvia miltiorrhiza and Panax notoginseng herb pair on acute myocardial ischemia injury.Jan 31, 2020

Pubmed Data : Phytomedicine. 2020 Feb ;67:153162. Epub 2019 Dec 26. PMID: 31955134
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Panax Notoginseng, Salvia miltiorrhiza
Diseases : Myocardial Ischemia
Pharmacological Actions : Cardioprotective
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An optimal combination of chemically pure compounds from Salvia miltiorrhiza for inhibiting cell proliferation.Feb 14, 2021

Pubmed Data : Cardiovasc Hematol Agents Med Chem. 2021 Feb 15. Epub 2021 Feb 15. PMID: 33593266
Article Published Date : Feb 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Atherosclerosis, Cardiovascular Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Cardioprotective
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Combination of Danshen and ligustrazine has dual anti-inflammatory effect on macrophages and endothelial cells.Sep 29, 2020

Pubmed Data : J Ethnopharmacol. 2020 Sep 30 ;266:113425. Epub 2020 Sep 30. PMID: 33010405
Article Published Date : Sep 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
Additional Keywords : Natural Substance/Drug Synergy
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Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocellular carcinoma progression.Nov 05, 2018

Pubmed Data : J Ethnopharmacol. 2018 Nov 6 ;231:98-112. Epub 2018 Nov 6. PMID: 30412748
Article Published Date : Nov 05, 2018
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Liver Cancer
Pharmacological Actions : Chemotherapeutic, MicroRNA modulator
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Danshen water extract shows potential neuroprotective effects in Caenorhabditis elegans.Sep 27, 2020

Pubmed Data : J Ethnopharmacol. 2020 Sep 28 ;266:113418. Epub 2020 Sep 28. PMID: 32991971
Article Published Date : Sep 27, 2020
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
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Diterpenoids isolated from the root of Salvia miltiorrhiza and their anti-inflammatory activity.Apr 08, 2019

Pubmed Data : Nat Prod Res. 2019 Apr 9:1-7. Epub 2019 Apr 9. PMID: 30961363
Article Published Date : Apr 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor
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Docking studies on potential mechanisms for decreasing insulin resistance by the tangzhiqing herbal formula.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:1057648. Epub 2020 Oct 9. PMID: 33133211
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Hawthorn, Mulberry, Paeoniflorin, Peony, Rutin, Salvia miltiorrhiza
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
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Effect of Salvia miltiorrhiza on acetylcholinesterase: Enzyme kinetics and interaction mechanism merging with molecular docking analysis.May 21, 2019

Pubmed Data : Int J Biol Macromol. 2019 May 22 ;135:303-313. Epub 2019 May 22. PMID: 31128195
Article Published Date : May 21, 2019
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor
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Enhancement of antioxidant and antibacterial activities of Salvia miltiorrhiza roots fermented with Aspergillus oryzae.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2020 Jan 1 ;9(1). Epub 2020 Jan 1. PMID: 31906298
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Salvia miltiorrhiza
Diseases : Bacillus Cereus infection
Pharmacological Actions : Anti-Bacterial Agents, Antioxidants
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Exploring the mechanisms underlying the therapeutic effect of Salvia miltiorrhiza on diabetic nephropathy.Feb 25, 2021

Pubmed Data : Biosci Rep. 2021 Feb 26. Epub 2021 Feb 26. PMID: 33634308
Article Published Date : Feb 25, 2021
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Renoprotective
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Lycorine inhibits tumor growth of human osteosarcoma cells.Dec 31, 2019

Pubmed Data : Am J Transl Res. 2020 ;12(9):5381-5398. Epub 2020 Sep 15. PMID: 33042426
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Osteosarcoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Cell cycle arrest, Wnt/β-catenin pathway down-regulation
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Overview of Salvia miltiorrhiza as a potential therapeutic agent for various diseases.Sep 12, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Sep 13 ;9(9). Epub 2020 Sep 13. PMID: 32933217
Article Published Date : Sep 12, 2020
Study Type : Review
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Cancers: All, Cardiovascular Diseases, Central Nervous System Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
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Pharmacological potential of the combination of Salvia miltiorrhiza and Carthamus tinctorius for diabetes mellitus and its cardiovascular complications.Dec 31, 2019

Pubmed Data : Pharmacol Res. 2020 03 ;153:104654. Epub 2020 Jan 13. PMID: 31945473
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Safflower, Salvia miltiorrhiza
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Cardioprotective
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Protocatechuic aldehyde from Salvia miltiorrhiza exhibits an anti-inflammatory effect through inhibiting MAPK signalling pathway.Nov 16, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2020 Nov 17 ;20(1):347. Epub 2020 Nov 17. PMID: 33203388
Article Published Date : Nov 16, 2020
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
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Salvia miltiorrhiza may offer a new strategy for prevention and treatment of diabetes and its complications.Feb 17, 2019

Pubmed Data : Phytomedicine. 2019 Feb 18 ;58:152871. Epub 2019 Feb 18. PMID: 30851580
Article Published Date : Feb 17, 2019
Study Type : Review
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Diabetic Complications
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents
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Salvianolic acid B and sodium tanshinone II A sulfonate prevent pulmonary fibrosis through anti-inflammatory and anti-fibrotic process.Jul 05, 2020

Pubmed Data : Eur J Pharmacol. 2020 Jul 6 ;883:173352. Epub 2020 Jul 6. PMID: 32645333
Article Published Date : Jul 05, 2020
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza, Tanshinone IIA
Diseases : Pulmonary Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents
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Salvianolic acid B attenuates renal interstitial fibrosis.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2020 Aug ;22(2):1325-1334. Epub 2020 Jun 15. PMID: 32626974
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Renoprotective
Additional Keywords : Dose Response
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The properties of S. miltiorrhiza indicate their therapeutic potential in Alzheimer's disease.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2016 ;54(1):18-24. Epub 2015 Apr 10. PMID: 25857808
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Alzheimer's Disease
Pharmacological Actions : Neurogenesis, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
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Therapeutic potential of Salviae Miltiorrhizae Radix against human diseases.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:7309073. Epub 2018 Jun 27. PMID: 30050659
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Nrf2 activation
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This study intends to provide reference for clinical use of traditional Chinese medicine to resist new coronavirus.Feb 29, 2020

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2020 Mar ;45(6):1225-1231. PMID: 32281329
Article Published Date : Feb 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Burdock, Ginger, Ginseng, Honeysuckle, Magnolia, Salvia miltiorrhiza
Diseases : Coronavirus Infection
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Cytokine Modulation, Cytokine Storm

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