Luteolin

Name	AC	CK
Inflammation	8	14
Brain Inflammation	8	12
Lung Cancer	8	11
Athletic Performance	1	10
Cancers: All	9	9
Lipopolysaccharide-Induced Toxicity	6	9
Liver Cancer	6	9
Alzheimer's Disease	5	8
Colorectal Cancer	6	7
Ischemia	2	7
Cancers: Drug Resistant	4	6
Colon Cancer	5	6
Escherichia coli Infections	2	6
Urinary Tract Infections	2	6
Breast Cancer: Triple Negative	4	5
Carcinoma: Non-Small-Cell Lung	4	5
Diabetic Complications	1	5
Hyperglycemia	1	5
Insulin Resistance	3	5
Memory Disorders	3	5
Obesity	3	5
Anxiety Disorders	2	4
Chemically-Induced Liver Damage	2	4
Depression	2	4
Gastric Cancer	3	4
Hepatic Steatosis	2	4
Learning disorders	2	4
Myocardial Ischemia	2	4
Neurodegenerative Diseases	3	4
Oxidative Stress	4	4
Prostate Cancer	3	4
Autism Spectrum Disorders	1	3
Brain: Microglial Activation	3	3
Cancer Metastasis	2	3
Endothelial Dysfunction	2	3
Glioblastoma	3	3
Melanoma	2	3
Multiple Sclerosis	2	3
Tumors	3	3
Acetaminophen (Tylenol) Toxicity	1	2
Atherosclerosis	1	2
Autism	1	2
Bisphenol Toxicity	1	2
Brain: Oxidative Stress	1	2
Breast Cancer	2	2
Chemotherapy-Induced Toxicity: Cisplatin	2	2
Chemotherapy-Induced Toxicity: Gentamicin	1	2
Chronic Pain	1	2
Colitis	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Cognitive Dysfunction	1	2
Dyslipidemias	1	2
Endometriosis	1	2
Epilepsy	1	2
Esophageal Cancer	2	2
Fibrosis	1	2
Hashimoto's thyroiditis	1	2
Heart Failure	1	2
Hepatoma	2	2
Hydrogen Peroxide Induced Toxicity	2	2
Hypercholesterolemia	1	2
Kidney Cancer	1	2
Kidney Damage	1	2
Kidney Damage: Chemically-Induced	1	2
Liver Cirrhosis	1	2
Liver Failure: Acute	1	2
Liver Fibrosis	1	2
Lung Cancer: Prevention	1	2
Lung Injury: Acute	1	2
Mercury Poisoning	1	2
Metabolic Syndrome X	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Ovarian Cancer	1	2
Parkinson's Disease	1	2
Pneumonia	1	2
Prenatal Nutrition: Health of the Offspring	1	2
Promyelocytic leukemia	2	2
Sepsis	1	2
Spinal Cord Injuries	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Adiponectin: Low Levels	1	1
Advanced Glycation End products (AGE)	1	1
Brain Ischemia	1	1
Breast Cancer: Lung Metastasis	1	1
Cancers: Canine	1	1
Cardiovascular Diseases	1	1
Central Nervous System Diseases	1	1
Chikungunya Virus	1	1
Cholesterol: Oxidation	1	1
Choriocarcinoma	1	1
Chronic Lymphocytic Leukemia	1	1
Cognitive Decline/Dysfunction	1	1
Endothelial Damage	1	1
Excitotoxicity	1	1
Gastrointestinal Inflammation	1	1
Gout	1	1
Heavy Metal Toxicity	1	1
Hyperinsulinism	1	1
Hyperuricemia	1	1
Hypoxia	1	1
Inflammatory Bowel Diseases	1	1
Leishmaniasis	1	1
Leukemia	1	1
Lyme Borreliosis	1	1
Lyme Disease	1	1
Osteoporosis	1	1
Pancreatic Cancer	1	1
Staphylococcus aureus: Methicillin-resistant (MRSA)	1	1
Thyroid Cancer	1	1
Tongue Cancer	1	1
Ultraviolet Radiation Induced Damage	1	1
Weight Problems	1	1

Name	AC	CK
Anti-Inflammatory Agents	30	53
Antioxidants	30	49
Apoptotic	40	46
Antiproliferative	27	33
Neuroprotective Agents	18	27
Nrf2 activation	13	25
Interleukin-6 Downregulation	12	22
Anti-metastatic	13	19
NF-kappaB Inhibitor	8	15
Tumor Necrosis Factor (TNF) Alpha Inhibitor	8	15
Hepatoprotective	5	13
Antineoplastic Agents	8	11
Renoprotective	5	10
Cardioprotective	5	9
Interleukin-1 beta downregulation	6	9
Cell cycle arrest	7	8
Heme oxygenase-1 up-regulation	5	8
Matrix metalloproteinase-2 (MMP-2) inhibitor	5	8
Matrix metalloproteinase-9 (MMP-9) inhibitor	5	8
MicroRNA modulator	5	8
Chemopreventive	5	7
Anti-Bacterial Agents	2	6
Anticarcinogenic Agents	4	6
Malondialdehyde Down-regulation	3	6
Chemosensitizer	4	5
Chemotherapeutic	4	5
Cyclooxygenase 2 Inhibitors	5	5
Enzyme Inhibitors	5	5
Angiogenesis Inhibitors	3	4
Anti-Apoptotic	4	4
Anti-Fibrotic	2	4
Antidepressive Agents	2	4
Superoxide Dismutase Up-regulation	2	4
Vascular Endothelial Growth Factor Inhibitors	3	3
Anticonvulsants	1	2
Antimicrobial	2	2
Antinoceceptive	1	2
Anxiolytic	1	2
Autophagy Up-regulation	1	2
C-Jun N-Terminal Kinases (JNK) Modulator	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Hypolipidemic	1	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	2
Immunosuppressive Agents	1	2
Interferon Gamma Reducer	1	2
Interleukin-2 Downregulation	1	2
Pancreato Protective Agents	1	2
Proteasome Inhibitors	2	2
Radioprotective	1	2
Regenerative	1	2
Vascular Endothelial Growth Factor A Inhibitor	2	2
Wnt/β-catenin signaling pathway modulation	2	2
anti-inflammatory	1	2
Anti-Angiogenic	1	1
Antiviral Agents	1	1
Bcl-2 protein down-regulation	1	1
Cytoprotective	1	1
Cytotoxicity	1	1
Hypoglycemic Agents	1	1
Hypoxia-inducible factor-1 (HIF-1) inhibitor	1	1
Immunomodulatory	1	1
Interferon Inducers	1	1
Interleukin-8 downregulation	1	1
Neuritogenic	1	1
Nitric Oxide Inhibitor	1	1
Photoprotective	1	1
Radiosensitizer	1	1
STAT3 Inhibitor	1	1
Vascular Endothelial Growth Factor Regulator	1	1
Vasodilator Agents	1	1
Xanthine oxidase inhibitor	1	1

[+]

Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.Oct 24, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2019 Oct 25 ;11(11). Epub 2019 Oct 25. PMID: 31731527

Article Published Date : Oct 24, 2019

Study Type : Human Study

Additional Links

Substances : Chlorogenic Acid, Luteolin

Diseases : Cardiovascular Diseases, Metabolic Syndrome X, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Cardioprotective, Hepatoprotective

[+]

Enhancement of exercise performance by 48 hours, and 15-day supplementation with mangiferin and luteolin in men.Feb 05, 2019

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Pubmed Data : Viruses. 2019 Jul 7 ;11(7). Epub 2019 Jul 7. PMID: 31284698

Article Published Date : Jul 06, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Apigenin, Flavonoids, Kaempferol, Luteolin

Diseases : Enterovirus 71

Pharmacological Actions : Antiviral Agents

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Pubmed Data : Int Immunopharmacol. 2020 Jun 13 ;85:106680. Epub 2020 Jun 13. PMID: 32544871

Article Published Date : Jun 12, 2020

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Myocardial Ischemia

Pharmacological Actions : Cardioprotective

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Luteolin ameliorated the myocardium fibrosis of heart failure.Jan 22, 2017

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Pubmed Data : Sci Rep. 2017 Jan 23 ;7:41017. Epub 2017 Jan 23. PMID: 28112209

Article Published Date : Jan 22, 2017

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Heart Failure

Pharmacological Actions : Anti-Fibrotic, Cardioprotective

[+]

Luteolin ameliorates diet-induced obesity and its comorbidities.Oct 02, 2018

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Pubmed Data : Nutrients. 2018 Oct 3 ;10(10). Epub 2018 Oct 3. PMID: 30282902

Article Published Date : Oct 02, 2018

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Fibrosis, Hepatic Steatosis, Insulin Resistance, Obesity

Pharmacological Actions : Anti-Fibrotic, Pancreato Protective Agents

Additional Keywords : Anti-Obesity Agents

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Luteolin ameliorates experimental lung fibrosis both in vivo and in vitro.Nov 23, 2010

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Pubmed Data : J Agric Food Chem. 2010 Nov 24 ;58(22):11653-61. Epub 2010 Oct 19. PMID: 20958047

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Pubmed Data : Antioxidants (Basel). 2019 Dec 21 ;9(1). Epub 2019 Dec 21. PMID: 31877779

Article Published Date : Dec 20, 2019

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Chemically-Induced Liver Damage, Lead Poisoning

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective

Problem Substances : Lead

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Luteolin could restore sensitivity of oxaliplatin resistant cell lines to chemotherapeutic drugs.Dec 31, 2013

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Pubmed Data : J Food Biochem. 2020 Jun 29:e13358. Epub 2020 Jun 29. PMID: 32598492

Article Published Date : Jun 28, 2020

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Hypercholesterolemia, Obesity

Pharmacological Actions : Anticholesteremic Agents, Hypoglycemic Agents

[+]

Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome.Mar 31, 2019

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Luteolin may have potential as a therapeutic agent for treating NAFLD.Nov 21, 2016

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Pubmed Data : Biochem Biophys Res Commun. 2016 Nov 22. Epub 2016 Nov 22. PMID: 27888103

Article Published Date : Nov 21, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Hypolipidemic

[+]

Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA in H22 hepatoma cells. Dec 31, 2014

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Pubmed Data : Genet Mol Res. 2015 ;14(4):14448-56. Epub 2015 Nov 19. PMID: 26600503

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Liver Cancer

Pharmacological Actions : Angiogenesis Inhibitors

Additional Keywords : Gene Expression

[+]

Luteolin may provide a promising preclinical therapeutic line in multiple sclerosis being anti-inflammatory, antiapoptotic, and neurotrophic agent.Aug 31, 2019

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Pubmed Data : IUBMB Life. 2019 Sep ;71(9):1401-1408. Epub 2019 Jun 11. PMID: 31185137

Article Published Date : Aug 31, 2019

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Multiple Sclerosis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents

[+]

Luteolin may represent a promising candidate for the treatment of intracerebral hemorrhage-induced secondary brain injury.Dec 31, 2018

Pubmed Data : Br J Pharmacol. 2020 Jan 24. Epub 2020 Jan 24. PMID: 31976547

Article Published Date : Jan 23, 2020

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Chemotherapy-Induced Toxicity: Irinotecan, Drug-Induced Toxicity: Gastrointestinal, Mucositis

Pharmacological Actions : Anti-Inflammatory Agents, Chemoprotective Agents, Gastroprotective, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Irinotecan

[+]

Luteolin prevents systemic metabolic alterations and vascular dysfunction associated with obesity.Dec 31, 2017

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Pubmed Data : IUBMB Life. 2020 Jun 1. Epub 2020 Jun 1. PMID: 32478470

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Pubmed Data : Phytomedicine. 2018 Oct 22 ;57:18-29. Epub 2018 Oct 22. PMID: 30668319

Article Published Date : Oct 21, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Liver Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, MicroRNA modulator

[+]

Modulatory effect of luteolin on redox homeostasis and inflammatory cytokines in a mouse model of liver cancer.Nov 30, 2016

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Pubmed Data : Brain Res. 2020 Oct 1 ;1744:146919. Epub 2020 May 30. PMID: 32485174

Article Published Date : Sep 30, 2020

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Electromagnetic Radiation Mitigation

Pharmacological Actions : Antioxidants, Neuroprotective Agents, Radioprotective

Anti Therapeutic Actions : Electromagnetic Radiation

[+]

Neuroprotective role of luteolin against lead acetate-induced cortical damage.Mar 24, 2020

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Pubmed Data : Hum Exp Toxicol. 2020 Mar 25:960327120913094. Epub 2020 Mar 25. PMID: 32208856

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Pubmed Data : J Tradit Complement Med. 2020 Jan ;10(1):60-69. Epub 2019 Feb 27. PMID: 31956559

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Uricosuric Agents

[+]

Protective effects of luteolin on nephrotoxicity induced by long-term hyperglycaemia.Mar 31, 2020

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Pubmed Data : Microb Pathog. 2020 Feb 11 ;142:104056. Epub 2020 Feb 11. PMID: 32058023

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Pubmed Data : Thyroid. 1999 Apr;9(4):369-76. PMID: 10319943

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Pubmed Data : Cell Death Dis. 2019 Mar 4 ;10(3):218. Epub 2019 Mar 4. PMID: 30833546

Article Published Date : Mar 03, 2019

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Chemotherapeutic

[+]

Differential effects of luteolin and its glycosides on invasion and apoptosis in MDA-MB-231 triple-negative breast cancer cells.Dec 31, 2018

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Pubmed Data : Curr Pharm Des. 2020 May 26. Epub 2020 May 26. PMID: 32452323

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Pubmed Data : Molecules. 2019 Feb 12 ;24(3). Epub 2019 Feb 12. PMID: 30759846

Article Published Date : Feb 11, 2019

Study Type : In Vitro Study

Additional Links

Substances : Luteolin, Thistle

Diseases : Alzheimer's Disease, Diabetes Mellitus: Type 2

Pharmacological Actions : Alpha-glucosidase inhibitor , Neuroprotective Agents

Additional Keywords : Plant Extracts

[+]

low concentration of luteolin attenuates doxorubicin-induced cytotoxicity to MCF-7 cells through a combination of antioxidant activity and an increase in levels of Bcl-2 protein. Dec 31, 2014

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Pubmed Data : Eur J Pharmacol. 2011 Apr 15. Epub 2011 Apr 15. PMID: 21513709

Article Published Date : Apr 15, 2011

Study Type : In Vitro Study

Additional Links

Substances : Chicoric Acid, Dandelion , Luteolin

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor

[+]

Luteolin and kaempferol are a good candidate for the complementary therapeutic agent against liver cancer.Apr 30, 2018

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Pubmed Data : Nutr Cancer. 2018 May-Jun;70(4):594-604. Epub 2018 Apr 25. PMID: 29693446

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Pubmed Data : Brain Res. 2015 Dec 10 ;1629:85-93. Epub 2015 Oct 22. PMID: 26471408

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Pubmed Data : Cytotechnology. 2010 Feb 17. Epub 2010 Feb 17. PMID: 20162352

Article Published Date : Feb 17, 2010

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Osteoporosis

[+]

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Pubmed Data : Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2018 Oct ;26(5):1425-1429. PMID: 30295262

Article Published Date : Sep 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Multiple Myeloma

Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Inhibitors

Additional Keywords : Dose Response

[+]

Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells Mar 22, 2016

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Pubmed Data : Free Radic Biol Med. 2016 Mar 23. Epub 2016 Mar 23. PMID: 27016074

Article Published Date : Mar 22, 2016

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Nitric Oxide Inhibitor, Nrf2 activation

[+]

Luteolin is a potential therapeutic candidate for melanoma.Jan 16, 2019

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Pubmed Data : Phytother Res. 2019 Jan 17. Epub 2019 Jan 17. PMID: 30653763

Article Published Date : Jan 16, 2019

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Melanoma

Pharmacological Actions : Anti-metastatic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Vascular Endothelial Growth Factor A Inhibitor

[+]

Luteolin is expounded to have great potential to target various genes and pathways to perform anti-inflammatory effects.Jun 23, 2020

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Pubmed Data : Int Immunopharmacol. 2020 Jun 24 ;86:106727. Epub 2020 Jun 24. PMID: 32593158

Pubmed Data : J Neuroinflammation. 2009;6:29. Epub 2009 Oct 13. PMID: 19825165

Article Published Date : Jan 01, 2009

Study Type : Commentary

Additional Links

Substances : Luteolin

Diseases : Multiple Sclerosis

[+]

Luteolin plays an important role in the treatment of human choriocarcinoma cells.Aug 30, 2016

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Pubmed Data : Biol Reprod. 2016 Aug 31. Epub 2016 Aug 31. PMID: 27580988

Article Published Date : Aug 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Choriocarcinoma

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Chemotherapeutic Synergy: Cisplatin, Natural Substance/Drug Synergy

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Luteolin supports osteogenic differentiation of human periodontal ligament cells.Oct 25, 2019

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Pubmed Data : Inflammopharmacology. 2018 Oct 1. Epub 2018 Oct 1. PMID: 30276558

Article Published Date : Sep 30, 2018

Study Type : In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Luteolin suppresses lipopolysaccharide‑induced cardiomyocyte hypertrophy and autophagy in vitro.Feb 28, 2019

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Pubmed Data : Cancer Lett. 2009 Aug 28;281(2):162-70. Epub 2009 Apr 2. PMID: 19344998

Article Published Date : Aug 28, 2009

Study Type : In Vitro Study

Additional Links

Substances : Luteolin, Quercetin, Ursolic Acid

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative , Apoptotic

[+]

Luteolin, quercetin, and antibiotics have complemented each another against MRSA.Nov 21, 2016

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Pubmed Data : Int J Mol Sci. 2016 Nov 22 ;17(11). Epub 2016 Nov 22. PMID: 27879665

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Pubmed Data : Pharmacol Res. 2020 Feb ;152:104579. Epub 2019 Nov 30. PMID: 31790820

Article Published Date : Jan 31, 2020

Study Type : Review

Additional Links

Substances : Luteolin, Omega-3 Fatty Acids, Probiotics, Sulforaphane

Diseases : Autism Spectrum Disorders

Pharmacological Actions : Gastrointestinal Agents

[+]

Phytochemicals and micronutrients may enhance efficacy of doxycycline in combating all the morphological forms of studied Borrelia sp.Dec 31, 2015

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Pubmed Data : Int J Biol Sci. 2016 ;12(9):1093-103. Epub 2016 Jul 22. PMID: 27570483

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Baicalein, Iodine, Luteolin, Rosmarinic acid, Vitamin C, Vitamin D

Diseases : Lyme Borreliosis, Lyme Disease

Pharmacological Actions : Antimicrobial

Additional Keywords : Natural Substance/Drug Synergy

[+]

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Pubmed Data : Environ Health Prev Med. 2010 Jan;15(1):18-26. PMID: 19960424

Article Published Date : Jan 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Luteolin, Reseda luteola

Pharmacological Actions : Antiproliferative , Apoptotic

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The anticancer effect of luteolin is mediated by downregulation of TAM receptor tyrosine kinasesJan 31, 2017

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Pubmed Data : Oncol Rep. 2017 Feb ;37(2):1219-1226. Epub 2016 Dec 23. PMID: 28035396

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View the Evidence: 237 Abstracts with Luteolin Research

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Altilix supplementation was a beneficial approach in the management of hepatic and cardiometabolic alterations in metabolic syndrome subjects.Oct 24, 2019

Enhancement of exercise performance by 48 hours, and 15-day supplementation with mangiferin and luteolin in men.Feb 05, 2019

Apigenin and Luteolin significantly activate the PI3K/Nrf2/ARE system, and this activation may be responsible for their anti-inflammatory effects.Apr 21, 2015

Combination treatments with luteolin and fisetin may be a potential candidate for the treatment and prevention of diabetes and its complications.Jun 25, 2017

Luteolin decreased the attachment and invasion of uropathogenic escherichia coli in bladder epithelial cells, attenuated UPEC-induced cytotoxicity and biofilm formation.Sep 30, 2014

Luteolin prevents angiotensin II-induced cardiac remodeling.Jan 01, 2015

Protective effect of luteolin on skin ischemia-reperfusion injury through an AKT-dependent mechanism.Oct 01, 2018

Palmitoylethanolamide and luteolin in combination could have beneficial effects in autism.Dec 31, 2016

Ameliorative effects of luteolin against endometriosis progression.Mar 02, 2019

Antiviral efficacy of flavonoids against enterovirus 71 infection.Jul 06, 2019

Anxiolytic effects of the flavonoid luteolin in a mouse model of acute colitisDec 25, 2019

Apigenin has good hepatoprotective effects and potential as a promising therapeutic agent for acute liver failure in clinical application.Jan 10, 2019

Co-ultramicronized palmitoylethanolamide and luteolin promotes neuronal regeneration after spinal cord injury.Dec 31, 2015

Combination of curcumin and luteolin synergistically inhibits TNF-α-induced vascular inflammation in human vascular cells and mice.Aug 14, 2019

Combination of luteolin and lycopene effectively protect against nonalcoholic fatty liver disease.Jun 19, 2020

Dietary luteolin protects against mercuric chloride induced renal injury.Nov 08, 2017

Effects of verbascoside and luteolin on oxidative damage in brain of heroin treated mice.Jun 30, 2005

Flavonoids could be used as protective agents against oxidative stress induced by gentamicin.Jul 31, 2018

Flavonoids may act as a prenatal preventive against increased interleukin-6 mediated maternal immune activiation associated with abnormal social interactions in adult offspring. Dec 10, 2009

Long-term supplementation with a luteolin enriched artichoke leaf extract can prevent adiposity and related metabolic disorders.Jul 26, 2018

Low dose of luteolin activates Nrf2 in the liver of mice.Dec 31, 2019

Luteolin alleviates LPS-induced bronchopneumonia injury in vitro and in vivoJul 29, 2018

Luteolin alleviates myocardial ischemia reperfusion injury.Jun 12, 2020

Luteolin ameliorated the myocardium fibrosis of heart failure.Jan 22, 2017

Luteolin ameliorates diet-induced obesity and its comorbidities.Oct 02, 2018

Luteolin ameliorates experimental lung fibrosis both in vivo and in vitro.Nov 23, 2010

Luteolin ameliorates ferric nitrilotriacetic acid induced renal toxicity and tumor promotional response in rat.May 01, 2009

Luteolin ameliorates testis injury and blood-testis barrier disruption.Mar 28, 2019

Luteolin and 5-flurouracil act synergistically to induce cellular weapons in experimentally induced solid ehrlich carcinomaAug 31, 2019

Luteolin attenuates acute lung injury in experimental mouse model of sepsis.Apr 10, 2018

Luteolin attenuates allergic nasal inflammation.Dec 31, 2019

Luteolin attenuates cardiac ischemia/reperfusion injury in diabetic animals.Dec 31, 2018

Luteolin attenuates diabetic nephropathy through suppressing inflammatory response and oxidative stress.Jan 01, 2020

Luteolin attenuates doxorubicin-induced cardiotoxicity.Dec 31, 2019

Luteolin attenuates sepsis‑induced myocardial injury.Apr 30, 2020

Luteolin can be a chemotherapeutic agent against colorectal cancer.Oct 31, 2014

Luteolin can reduce the inflammatory response of acute gouty arthritis.Feb 27, 2020

Luteolin confers renoprotection against ischemia-reperfusion injury.May 13, 2019

Luteolin could ameliorate the cognitive dysfunctions in streptozotocin-induced diabetic rat model.Aug 06, 2018

Luteolin could be a promising candidate molecule for atherosclerosis.Dec 31, 2018

Luteolin could diminish lead overload in hepatic tissues.Dec 20, 2019

Luteolin could restore sensitivity of oxaliplatin resistant cell lines to chemotherapeutic drugs.Dec 31, 2013

Luteolin decreases atherosclerosis in LDL receptor-deficient mice.Aug 31, 2018

Luteolin effectively suppressed metastases of breast cancer by reversing epithelial-mesenchymal transition.Jan 31, 2017

Luteolin had a protective effect against acetaminophen-induced liver injury in mice.Jun 30, 2015

Luteolin had an anticonvulsant effect in an acute pentylenetetrazole model.Nov 30, 2017

Luteolin has a protective and regenerative effecct against chemically-induced liver fibrosis. Dec 15, 2009

Luteolin improves hypercholesterolemia and glucose intolerance. Jun 28, 2020

Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome.Mar 31, 2019

Luteolin inhibits invasion of prostate cancer cells. Jun 01, 2009

Luteolin inhibits LPS-induced IL-6 production in the brain by inhibiting the JNK signaling pathway and activation of AP-1 in microglia and may be useful for mitigating neuroinflammation.May 26, 2008

Luteolin inhibits melanoma growth in vitro and in vivo.Jun 30, 2020

Luteolin inhibits proliferation and induces apoptosis of human melanoma cells.Jan 20, 2019

Luteolin may be a potential candidate for NSCLC therapy, especially for treatment of patients with acquired erlotinib-resistant NSCLC.May 31, 2014

Luteolin may have potential as a therapeutic agent for treating NAFLD.Nov 21, 2016

Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA in H22 hepatoma cells. Dec 31, 2014

Luteolin may provide a promising preclinical therapeutic line in multiple sclerosis being anti-inflammatory, antiapoptotic, and neurotrophic agent.Aug 31, 2019

Luteolin may represent a promising candidate for the treatment of intracerebral hemorrhage-induced secondary brain injury.Dec 31, 2018

Luteolin may serve as an effective anti-tumor drug in gastric cancer treatment.Feb 26, 2017

Luteolin may suppress experimental colitis through the Nrf2 signaling pathway.Aug 24, 2016

Luteolin mediates the antidepressant-like effects of Cirsium japonicum in mice.Jan 31, 2014

Luteolin possess potent anti-nociceptive and anti-inflammatory properties and can thus be used in pain management.Dec 31, 2017

Luteolin prevents intestinal mucositis induced by irinotecan.Jan 23, 2020

Luteolin prevents systemic metabolic alterations and vascular dysfunction associated with obesity.Dec 31, 2017

Luteolin promotes long-term potentiation and improves cognitive functions in chronic cerebral hypoperfused rats.Feb 10, 2010

Luteolin protects against amyloid beta peptide-induced toxicity in mice. Sep 15, 2009

Luteolin protects against diabetic cardiomyopathy by inhibiting NF-κB-mediated inflammation and activating the Nrf2-mediated antioxidant responses.May 31, 2019

Luteolin protects against testicular injury induced by lead acetate.May 31, 2020

Luteolin protects mice from chemically induced liver damage. Apr 01, 2009

Luteolin protects the hypercholesterolemic heart against ischemia/reperfusion injury.Apr 17, 2018

Luteolin reduces adipose tissue macrophage inflammation and insulin resistance in postmenopausal obese mice.Aug 31, 2019

Luteolin reduces high glucose-mediated impairment of endothelium-dependent relaxation in rat aorta by reducing oxidative stress.Nov 03, 2009

Luteolin

View the Evidence:
237 Abstracts with Luteolin Research