Folic Acid

Name	AC	CK
High Homocysteine	11	113
Alzheimer's Disease	13	63
Cognitive Decline/Dysfunction	5	50
Folic Acid/Folate Deficiency	7	45
Polycystic Ovary Syndrome	4	40
Inflammation	3	31
Cardiovascular Diseases	2	30
Prenatal Nutrition: Learning/Intelligence of Offspring	2	30
Hyperhomocysteinemia	3	22
Cervical Cancer	3	21
C-Reactive Protein	1	20
Cervical Dysplasia	2	20
Congenital Defects	1	20
Neurologic Disorders	2	20
Peripheral Arterial Disease	2	20
Prenatal Nutrition	1	20
Stroke	2	20
Endothelial Dysfunction	3	14
Dementia	3	13
Neurodegenerative Diseases	3	13
Prenatal Nutrition: Health of the Offspring	3	13
Colon Cancer	2	12
Homocysteine: Elevated	2	12
Hypertension	2	12
Drug-Induced Toxicity: Methotrexate	2	11
Migraine Disorders	2	11
Postpartum Depression	2	11
Restless Legs Syndrome	2	11
Stroke: Prevention	2	11
Vitiligo	2	11
Acne	1	10
Air Pollution Linked Toxicity	1	10
Anemia	1	10
Arsenic Poisoning	1	10
Arthritis: Rheumatoid	1	10
Autism Spectrum Disorders	1	10
Birth: Labor & Delivery	1	10
Bladder Cancer	1	10
Breast Cancer	1	10
Buerger Disease	1	10
Cardiovascular Disease	1	10
Carotid Stenosis	1	10
Chemotherapy Induced Myelotoxicity	1	10
Chemotherapy-Induced Toxicity	1	10
Cleft Lip	1	10
Colitis: Ulcerative	1	10
Common variable immunodeficiency (CVID)	1	10
Coronary Artery Disease	1	10
Corticosteroid-Induced Toxicity	1	10
Cortisone Toxicity	1	10
Cystic Fibrosis	1	10
Diabetes Mellitus: Type 1: Prevention	1	10
Drug Induced Toxicity: Metformin	1	10
Endometrial Cancer	1	10
Erectile Dysfunction	1	10
Esophageal Cancer	1	10
Gastritis	1	10
Gastroesophageal Reflux	1	10
Giant Cell Arteritis	1	10
Glaucoma	1	10
Headache: Migraine	1	10
Hepatitis	1	10
Hepatitis A	1	10
Hepatitis B	1	10
Hepatitis C	1	10
Hypercholesterolemia	1	10
Hypertension: Pre-Eclampsia Induced	1	10
Hyperuricemia	1	10
Infants: Low Birth Weight	1	10
Insulin Resistance	1	10
Intima Media Thickening	1	10
Kidney Transplant	1	10
Laryngeal Cancer	1	10
Lewy Body Disease	1	10
Macular Degeneration	1	10
Mucositis	1	10
Multiple Sclerosis	1	10
Myocardial Infarction	1	10
Neutropenia: Chemotherapy Induced	1	10
Oligomenorrhea	1	10
Pancreatic Cancer	1	10
Peripheral Vascular Diseases	1	10
Polymyalgia Rheumatica	1	10
Postpartum Blood Loss	1	10
Postpartum Hemorrhage	1	10
Pre-Eclampsia	1	10
Pregnancy Complications	1	10
Prostate Cancer	1	10
Rheumatoid Arthritis	1	10
Rosacea	1	10
Sleep Apnea: Central	1	10
Spina Bifida	1	10
Spinal Cord Diseases	1	10
Spondylitis: Ankylosing	1	10
Squamous cell carcinoma	1	10
Trigeminal Neuralgia	1	10
Vitamin B 12 Deficiency	1	10
Wernicke Encephalopathy	1	10
Aluminum Toxicity	3	5
Alcohol Toxicity	2	4
Atherosclerosis	2	4
Lead Poisoning	2	4
Oxidative Stress	2	4
Testicular Injury: Chemical/Metal Induced	2	4
Aging: Brain	2	3
Infertility: Female	2	3
Parkinson's Disease	2	3
Anxiety Disorders	1	2
Bacterial Meningitis	1	2
Bisphenol Toxicity	1	2
Bisphenol-A Toxicity	1	2
Chemically-Induced Liver Damage	1	2
Chemotherapy-Induced Toxicity: Doxorubicin	1	2
Drug Toxicity: Methotrexate	1	2
High Fat Diet	1	2
Hypertension: Pulmonary	1	2
Hyperthyroidism	1	2
Infertility	1	2
Infertility: Male	1	2
Mobile Phone-Induced Oxidative Stress	1	2
Pneumococcal Infections	1	2
Prenatal Chemical Exposures	1	2
Right Ventricular Hypertrophy	1	2
Seizures	1	2
Aging	1	1
Amyotrophic Lateral Sclerosis	1	1
Autism	1	1
DNA damage	1	1
Depression	1	1
Depressive Disorder	1	1
Diabetes Mellitus: Type 2	1	1
Hypoxia	1	1
Inflammatory Bowel Diseases	1	1
Leukemia	1	1
Liver Cancer	1	1
Menstrual Migraine	1	1
Migraine: Menstrual Cycle Induced	1	1
Mitochondrial Dysfunction	1	1
Neurodevelopmental Disorders	1	1
Nicotine/Tobacco Toxicity	1	1

Name	AC	CK
Anti-Inflammatory Agents	9	75
Neuroprotective Agents	18	72
Chemopreventive	5	41
Antioxidants	13	32
Chemotherapeutic	2	11
Antineoplastic Agents	1	10
Interleukin-6 Downregulation	1	10
Prophylactic Agents	1	10
Proton Pump Inhibitor	1	10
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	10
Uricosuric Agents	1	10
Cardioprotective	3	6
Hepatoprotective	3	6
Cytoprotective	2	4
Radioprotective	2	3
Anti-Apoptotic	2	2
Anti-atherogenic	1	2
Anticarcinogenic Agents	1	2
Anticonvulsants	1	2
Antimutagenic Agents	1	2
Antiproliferative	1	2
Apoptotic	1	2
Chemoprotective Agents	1	2
Genoprotective	1	2
Interleukin-1 beta downregulation	1	2
NF-kappaB Inhibitor	1	2
Nitric Oxide Enhancer	1	2
Chemosensitizer	1	1
MicroRNA modulator	1	1
Pancreato Protective Agents	1	1

[+]

A combination of nicotinamide 750 mg, zinc 25 mg, copper 1.5 mg, and folic acid 500 microg, marketed as Nicomide, appears to be an effective oral therapy for the treatment of acne vulgaris and rosacea. Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Cutis. 2006 Jan;77(1 Suppl):17-28. PMID: 16871775

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Copper, Folic Acid , Vitamin B-3 (Niacin), Zinc

Diseases : Acne, Rosacea

Pharmacological Actions : Anti-Inflammatory Agents

[+]

A dietary supplement containing melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine, is superior to omeprazole in treating GERD. Oct 01, 2006

Click here to read the entire abstract

Pubmed Data : J Pineal Res. 2006 Oct;41(3):195-200. PMID: 16948779

Article Published Date : Oct 01, 2006

Study Type : Human Study

Additional Links

Substances : Betaine , Folic Acid , Melatonin, Methionine, Tryptophan, Vitamin B-12, Vitamin B-6

Diseases : Gastroesophageal Reflux

Pharmacological Actions : Proton Pump Inhibitor

Additional Keywords : Superiority of Natural Substances versus Drugs

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A maternal daily intake of 400 µg folic acid alone significantly reduced the risks of infant low birth weight and small-for-gestational-age status.May 21, 2017

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Pubmed Data : J Pediatr. 2017 May 22. Epub 2017 May 22. PMID: 28545876

Article Published Date : May 21, 2017

Study Type : Human Study

Additional Links

Substances : Folic Acid

Diseases : Infants: Low Birth Weight

Additional Keywords : Risk Reduction

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A multi-vitamin/nutrient formula has therapeutic value in early-stage Alzheimer's diease. Dec 01, 2008

Click here to read the entire abstract

Pubmed Data : Am J Alzheimers Dis Other Demen. 2008 Dec-2009 Jan;23(6):571-85. Epub 2008 Dec 1. PMID: 19047474

Article Published Date : Dec 01, 2008

Study Type : Human Study

Additional Links

Substances : Carnitine, Acetyl-L-, Folic Acid , NAC (N-acetyl-L-cysteine), SAMe (S-adenosylmethionine), Vitamin B-6, Vitamin E

Diseases : Alzheimer's Disease

[+]

Click here to read the entire abstract

Pubmed Data : Urologia. 2013 Apr 24 ;80 Suppl 22:5-10. Epub 2013 Jan 16. PMID: 23334883

Pubmed Data : Rheumatology (Oxford). 2003 Sep;42(9):1055-61. Epub 2003 Apr 16. PMID: 12730520

Article Published Date : Sep 01, 2003

Study Type : Human Study

Additional Links

Substances : Folic Acid , Vitamin B-12

Diseases : Corticosteroid-Induced Toxicity, Cortisone Toxicity , Giant Cell Arteritis, Hyperhomocysteinemia, Polymyalgia Rheumatica

[+]

Enalapril-folic acid therapy, compared with enalapril alone, can significantly reduce the magnitude of the increase of UA concentrations in hypertensive adultsJan 31, 2017

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Pubmed Data : Am J Clin Nutr. 2017 Feb 1. Epub 2017 Feb 1. PMID: 28148501

Article Published Date : Jan 31, 2017

Study Type : Human Study

Additional Links

Substances : Folic Acid

Diseases : Hyperuricemia

Pharmacological Actions : Uricosuric Agents

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Environmental arsenic exposure reduces the effectiveness of folic acid supplementation in preventing myelomeningocele.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Folic acid supplement in subjects with mild cognitive impairment can improve cognitive performance and reduce peripheral inflammatory levels.Nov 22, 2016

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Pubmed Data : Sci Rep. 2016 Nov 23 ;6:37486. Epub 2016 Nov 23. PMID: 27876835

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Pubmed Data : Mediators Inflamm. 2016 ;2016:5912146. Epub 2016 Jun 2. PMID: 27340344

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Folic Acid , Vitamin B-12

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Folic acid supplementation reduced the risk of first stroke associated with elevated total cholesterol by 31% among hypertensive adults.Oct 31, 2016

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Pubmed Data : Stroke. 2016 Nov ;47(11):2805-2812. Epub 2016 Aug 11. PMID: 27729579

Higher consumption of folate may contribute to the prevention of peripheral arterial disease. Sep 01, 2003

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Pubmed Data : J Nutr. 2003 Sep;133(9):2863-7. PMID: 12949378

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Arch Ital Urol Androl. 2019 Jul 2 ;91(2). Epub 2019 Jul 2. PMID: 31266276

Article Published Date : Jul 01, 2019

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Pubmed Data : Arch Intern Med. 2009 Feb 23;169(4):335-41. PMID: 19237716

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Am Heart Assoc. 2016 Aug 15 ;5(8). Epub 2016 Aug 15. PMID: 27528407

Article Published Date : Aug 14, 2016

Study Type : Human Study

Additional Links

Substances : Folic Acid

Diseases : Cardiovascular Disease, Stroke

Additional Keywords : Risk Reduction

[+]

These results suggest a protective effect of folic acid supplement use on risk of small for gestational age.Jan 18, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2020 01 19 ;17(2). Epub 2020 Jan 19. PMID: 31963813

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[+]

Curcumin could protect against the vascular side effects of methotrexate by preventing an increase in oxidative stress.Nov 15, 2015

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Pubmed Data : Can J Physiol Pharmacol. 2015 Nov 16:1-8. Epub 2015 Nov 16. PMID: 26571019

Article Published Date : Nov 15, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin, Folic Acid

Diseases : Drug Toxicity: Methotrexate, Endothelial Dysfunction, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.Apr 30, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Invest. 2010 May ;120(5):1603-16. Epub 2010 Apr 26. PMID: 20424322

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Pubmed Data : Neurotox Res. 2019 Nov 13. Epub 2019 Nov 13. PMID: 31721048

Article Published Date : Nov 12, 2019

Study Type : Animal Study

Additional Links

Substances : Folic Acid

Diseases : Homocysteine: Elevated

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents

[+]

Folic acid could act as a highly effective fighting approach against lead-associated testicular toxicity.Jun 30, 2017

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Pubmed Data : Gen Physiol Biophys. 2017 Jul ;36(3):297-308. PMID: 28635608

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Pubmed Data : Cell Mol Neurobiol. 2011 Jan;31(1):83-91. Epub 2010 Dec 18. PMID: 21170581

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Folic Acid

Diseases : Aging: Brain

Pharmacological Actions : Neuroprotective Agents

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Folic acid improves developmental toxicity induced by aluminum sulphates.Feb 28, 2017

Additional Keywords : Gene Expression Regulation

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Vitamin B complex mitigates cardiac dysfunction in high-methionine diet-induced hyperhomocysteinemia.Mar 05, 2018

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Pubmed Data : Clin Exp Pharmacol Physiol. 2018 Mar 6. Epub 2018 Mar 6. PMID: 29509296

Article Published Date : Mar 05, 2018

Study Type : Animal Study

Additional Links

Substances : Folic Acid , Vitamin B-12, Vitamin B-6

Diseases : Hyperhomocysteinemia

Pharmacological Actions : Cardioprotective

Additional Keywords : Cardioprotective, folic acid, Hyperhomocysteinemia, Vitamin B-12, Vitamin B-6

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2019 Jan 14 ;20(2). Epub 2019 Jan 14. PMID: 30646578

Article Published Date : Jan 13, 2019

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2019 Dec 20 ;21(1). Epub 2019 Dec 20. PMID: 31861819

Article Published Date : Dec 19, 2019

Study Type : In Vitro Study

Additional Links

Substances : Folic Acid

Diseases : Neurodegenerative Diseases

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents

[+]

Folic acid induces methylation potential-dependent DNMT enzymes, thereby attenuating Aβ production.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Lancet. 2007 Jun 2;369(9576):1876-82. PMID: 17544768

Article Published Date : Jun 02, 2007

Study Type : Review

Additional Links

Substances : Folic Acid

Diseases : Stroke: Prevention

Additional Keywords : Meta-Analysis

[+]

Folic acid supplementation in patients taking SSRIs may reduce the risk of new onset diabetes via protection of normal beta cell function.Aug 31, 2014

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Pubmed Data : J Affect Disord. 2014 Sep ;166:6-13. Epub 2014 May 4. PMID: 25012404

Article Published Date : Aug 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Folic Acid

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Pancreato Protective Agents

Additional Keywords : Increased Risk, Risk Reduction

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Folic acid supplementation in pregnancy may have beneficial effects on the neurodevelopment of children.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Genes Nutr. 2017 ;12:14. Epub 2017 Jun 2. PMID: 28588742

Article Published Date : Dec 31, 2016

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Pubmed Data : Br J Dermatol. 2009 Mar;160(3):622-8. Epub 2008 Oct 20. PMID: 18945303

Article Published Date : Mar 01, 2009

Study Type : Review

Additional Links

Substances : Folic Acid

Diseases : Drug-Induced Toxicity: Methotrexate

[+]

Targeting mitochondria with folic acid and vitamin B12 ameliorates nicotine mediated islet cell dysfunction.Aug 31, 2018

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Pubmed Data : Environ Toxicol. 2018 Sep ;33(9):988-1000. Epub 2018 Jul 4. PMID: 29972271

Article Published Date : Aug 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Folic Acid , Vitamin B-12

Diseases : Mitochondrial Dysfunction , Nicotine/Tobacco Toxicity

Pharmacological Actions : Antioxidants

[+]

These results demonstrat the radioprotective effect of folic acid supplementation on low dose ionizing radiation-induced genomic instability in vitro.Dec 31, 2015

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Pubmed Data : Indian J Exp Biol. 2016 08 ;54(8):537-43. PMID: 28577512

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Folic Acid

Diseases : DNA damage

Pharmacological Actions : Anti-Apoptotic, Radioprotective

Additional Keywords : Anti-Apoptotic, DNA damage, folic acid, Radioprotective

Anti Therapeutic Actions : Low Dose Ionizing Radiation

[+]

Vitamin supplementation shows promise for the treatment of migraines with aura and menstrual induced migraines.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2015;2015:469529. Epub 2015 Feb 28. PMID: 25815319

Article Published Date : Dec 31, 2014

Study Type : Review

View the Evidence: 160 Abstracts with Folic Acid Research

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Dietary folate is associated with a significantly decreased risk of preterm birth.Dec 31, 2018

Folic acid supplementation during pregnancy significantly decreases the risk of congenital heart defects in newborns.Nov 08, 2016

Folic aicd combined with vitamin B6 and B12 treatment significantly reduced plasma homocysteine levelMay 31, 2015

Prenatal micronutrient supplementation, particularly iron/folic acid supplementation, was positively associated wtih aspects of intellectual functioning including working memory, inhibitory control, and fine motor functioning among offspring. Dec 22, 2010

This meta-analysis suggested that folic acid supplementation could significantly lower the serum CRP level.Dec 05, 2018

Vitamin B supplementation was effective in reducing serum homocysteine levels.Dec 31, 2016

5-methyltehydrofolate (folic acid) and vitamin B12 ameliorate red blood cell abnormalities in pediatric patients with Cystic Fibrosis. Jan 01, 2009

A case-control nutrigenomic study on the synergistic activity of folate and vitamin B12 in cervical cancer progression.Dec 31, 2011

A combination of nicotinamide 750 mg, zinc 25 mg, copper 1.5 mg, and folic acid 500 microg, marketed as Nicomide, appears to be an effective oral therapy for the treatment of acne vulgaris and rosacea. Jan 01, 2006

A dietary supplement containing melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine, is superior to omeprazole in treating GERD. Oct 01, 2006

A maternal daily intake of 400 µg folic acid alone significantly reduced the risks of infant low birth weight and small-for-gestational-age status.May 21, 2017

A multi-vitamin/nutrient formula has therapeutic value in early-stage Alzheimer's diease. Dec 01, 2008

A multi-vitamin/nutrient formula has therapeutic value in moderate-stage to later-stage Alzheimer's diease. Feb 01, 2009

Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin. Jun 01, 2005

Anemia in 85-year-old subjects is associated with folate deficiency and elevated homocysteine levels. Nov 10, 2008

B vitamins appear to slow cognitive and clinical decline in people with mild cognitive impairment, in particular in those with elevated homocysteine.Jul 21, 2011

B vitamins attenuate the epigenetic effects of ambient fine particles.Mar 12, 2017

Beneficial effects of pollen extract in association with vitamins for pain relief in patients affected by chronic prostatitis/chronic pelvic pain syndrome.Apr 23, 2013

Combined treatment with folic acid, vitamin B6, and vitamin B12 lowers homocysteine concentrations.May 17, 2018

D-chiro-inositol plus folic acid oral supplementation can improve metabolic control in overweight T1D patients.Dec 31, 2016

Dietary folate consumption as reflected in plasma folate and not supplementation with folic acid is inversely associated wtih prostate cancer risk. Mar 18, 2009

Dietary folate intake decreases the risk of endometrial cancer. Feb 01, 2007

Dietary folate is inversely associated with the risk of esophageal squamous-cell carcinoma.Mar 01, 2006

Effect of B vitamins supplementation on cardio-metabolic factors in patients with stable coronary artery disease.Dec 31, 2019

Elevated homocysteine levels associated with polymyalgia rheumatica and giant cell arteritis and the corticosteroid therapy used to treat these conditions may be attenuated with vitamin B12 and folic acid. Sep 01, 2003

Enalapril-folic acid therapy, compared with enalapril alone, can significantly reduce the magnitude of the increase of UA concentrations in hypertensive adultsJan 31, 2017

Environmental arsenic exposure reduces the effectiveness of folic acid supplementation in preventing myelomeningocele.Dec 31, 2014

Flower pollen extract in association with vitamins versus Serenoa repens in chronic prostatitis/chronic Pelvic pain syndrome.Dec 31, 2018

Folate improves the effect of metformin treatment on vascular endothelial function in women with polycystic ovary sydrome. Feb 01, 2010

Folate reduces plasma homocysteine and improves arterial function in patients with peripheral arterial disease. Sep 01, 2009

Folate supplementation for 8 weeks among women with PCOS had beneficial effects on metabolic profiles.Jun 30, 2014

Folate supplementation is protective against methotrexate induced side effects to the oral and gastrointestinal systems. Jan 01, 2000

Folate, riboflavin, thiamin and vitamin b12 protect against premalignant cervical lesions.Nov 01, 2003

Folic acid appears to prevent and/or reverse precancerous lesions associated with gastritis. Jan 01, 2003

Folic acid deficiency may play a key role in neurodegenerative disorders. Jun 15, 2007

Folic acid may have a protective effect against cell proliferation in patients with ulcerative colitis.Jun 01, 1997

Folic acid may have a therapeutic effect in treating viral hepatitis.Jul 01, 1999

Folic acid may help with erectile dysfunction.Aug 24, 2015

Folic acid supplement in subjects with mild cognitive impairment can improve cognitive performance and reduce peripheral inflammatory levels.Nov 22, 2016

Folic acid supplement use during pregnancy is associated with improved neurodevelopment in children. May 01, 2009

Folic acid supplementation in early pregnancy, aimed to prevent neural tube defects, may also reduce mental health problems in children.Nov 01, 2003

Folic acid supplementation lowers blood arsenic concentrations. Oct 01, 2007

Folic acid supplementation may have a certain role in the treatment of children with autism.Jun 06, 2016

Folic acid supplementation mitigates Alzheimer's disease by reducing inflammation.Dec 31, 2015

Folic acid supplementation reduced the risk of first stroke associated with elevated total cholesterol by 31% among hypertensive adults.Oct 31, 2016

Folic acid supplementation reduces hypertensive disorders during pregnancy. Jan 01, 2009

Folic acid supplementation results in significant intima media thickness reduction after 18 months in patients with at least one cardiovascular risk.Feb 06, 2009

High dosage of folic acid supplement from 3 months before pregnancy until the entire pregnancy reduces the recurrent pre-eclampsia.Jan 13, 2020

High dose folic acid supplementation is associated with a significant reduction in the recurrrence of colon cancers. Jul 28, 2008

High intake of dietary folate was associated with an overall decrease in bladder cancer risk.Jan 01, 2005

Higher consumption of folate may contribute to the prevention of peripheral arterial disease. Sep 01, 2003

Homocysteine levels in the tear fluid and plasma of patients with primary open-angle glaucoma is often elevated, indicating that inadequate vitamin b levels (e.g. b6, b12, and folate) may contribute to the disease.Jan 01, 2008

Homocysteine levels may be elevated in obstructive sleep apnea. Sep 01, 2001

It is possible that cervical dysplasia is caused by a derangement in folate metabolism or folate deficiency, and may be corrected through supplementation. Jan 01, 1982

L-arginine, folic acid, B6 and B12 may have therapeutic benefit in Buerger's disease. Oct 01, 2006

Low intake of folate, and b2, potassium, iron and vitamin A of plant origin, increase the risk for ischemic stroke.Dec 01, 2008

Low levels of serum folate were correlated with an increased severity of laryngeal squamous cell carcinoma.Nov 30, 2016

Lowering homocysteine with folic acids, B-6 and B-12 may have a therapeutic effect on migraine headaches. Jun 01, 2009

Moderate consumption of riboflavin may be protective against postpartum depression.Jul 31, 2000

Multi-nutrient supplementation improved cognition and mobility in able older females at clinically relevant levels.Jan 31, 2016

Myo-inositol plus folic acid has a beneficial effect in improving ovarian function in women with oligomenorrhea and polycystic ovaries. Sep 01, 2007

ncreased folate and vitamin B6 intakes seem to reduce homocysteine concentrations among transplant recipients with normal renal function, and could contribute to reducing the risk of chronic allograft dysfunction development.Mar 01, 1996

Neurological diseases are commonly associated with decreased serum folate levels among the Japanese. Jun 01, 2001

Oral administration of pollen extract in association with vitamins could lower the inflammatory state created by repeated prostate biopsies. Jul 01, 2019

Patients with common variable immunodeficiency have enhanced oxidative stress and high homocysteine levels associated with deficiencies of basic vitamins is Sep 01, 1997

Periconceptional folic acid supplementation can significantly reduce the risk of orofacial clefts.Feb 28, 2015

Prenatal folic acid-iron supplementation reduced the risk of obstetric complications in this South Asian setting.Jul 01, 2009

Restless leg syndrome may be associated with a deficiency of folic acid. Aug 07, 1976

Serum homocysteine levels are high in patients with ankylosing spondylitis indicating that therapeutic role of folic acid. Aug 01, 2007

Supplementation of folic acid with pyridoxine could decrease the characteristics of migraine attacks including headache severity and attack frequency.May 31, 2017

Supplementation with folic acid, pyridoxine, and cyanocobalamin may reduce the risk of age-related macular degeneration.Feb 23, 2009

The consumption of folate rich foods (not from supplements) is associated with reduced pancreatic cancer risk. Mar 15, 2006

Folic Acid

View the Evidence:
160 Abstracts with Folic Acid Research