Delta-tetrahydrocannabinol THC - Page 1 | GreenMedInfo

Name	AC	CK
Multiple Sclerosis	43	313
Epilepsy	34	158
Neuropathic Pain	14	119
Inflammation	42	86
Tourette Syndrome	8	75
Cancers: All	38	63
Inflammatory Bowel Diseases	13	59
Pain	8	57
Epilepsy: Childhood	6	56
Anxiety	13	53
Morphine Tolerance/Dependence	6	50
Seizures	8	42
Glioma	19	40
Huntington Disease	10	40
Opioid Tolerance/Dependence	1	40
Stroke	2	40
Stroke: Attenuation/Recovery	6	39
Chronic Pain	9	38
Glioblastoma Multiforme	10	38
Parkinson's Disease	13	36
Spinal Cord Injuries	4	34
Dravet syndrome	5	33
Muscle Spasticity	3	32
Diabetes Mellitus: Type 2	7	31
Neurodegenerative Diseases	21	31
Brachial Plexus Neuropathies	2	30
Anxiety Disorders	8	29
Breast Cancer	18	29
Brain Inflammation	17	27
Oxidative Stress	13	27
Sleep Disorders	5	27
Alzheimer's Disease	18	26
Amyotrophic lateral sclerosis (ALS)	4	24
Depression	11	24
Schizophrenia	11	24
Insomnia	3	23
Obsessive-Compulsive Disorder	4	23
Bladder Dysfunction	2	22
Lung Cancer	12	22
Marijuana Addiction/Withdrawal	3	22
Memory Disorders	5	22
Post-Traumatic Stress Disorders (PTSD)	8	22
Autism Spectrum Disorders	3	21
Cancer Metastasis	11	21
Hypoglycemia	1	20
Overactive Bladder	1	20
Peripheral Nerve Diseases	1	20
Dementia	5	19
Lipopolysaccharide-Induced Toxicity	10	19
Stroke: Ischemic	4	19
Brain Cancer	4	18
Colitis	7	17
HIV Infections	5	17
Diabetic Neuropathies	3	16
Glioblastoma	8	16
Hyperalgesia	6	16
Nonalcoholic fatty liver disease (NAFLD)	3	16
Acne	2	15
Brain Ischemia	7	15
Ulcerative Colitis	2	15
Brain: Microglial Activation	6	14
Astrocytoma	4	13
Brain Damage: Hypoxic Ischemic Insult	6	13
Chemotherapy-Induced Toxicity: Cisplatin	4	13
Psychoses	4	13
Brain Injury: Traumatic	2	12
Epileptic Seizures	2	12
Hypertension	2	12
Prostate Cancer	10	12
Amyotrophic Lateral Sclerosis	7	11
Colon Cancer	7	11
Endocannabinoid Disorders	2	11
Lennox-Gastaut Syndrome	2	11
Skin Cancer	5	11
Anorexia: Dementia-Associated	1	10
Attention Deficit Hyperactivity Disorder	1	10
Cardiovascular Diseases	4	10
Cerebral Ischemia	4	10
Cognitive Decline/Dysfunction	5	10
Crack Addiction/Withdrawal	1	10
Delirium: Drug-Induced	1	10
Dry Skin	1	10
Glaucoma	4	10
Impairment: Driving Related	1	10
Incontinence	1	10
Nausea: Pregnancy-Associated	1	10
Neurogenic Bladder	1	10
Neuropathic Pain: HIV-associated	1	10
Neuropathy: HIV associated	1	10
Obesity	5	10
Organ Transplantation: Kidney	1	10
Pancreatitis: Chronic	1	10
Phantom Limb	1	10
Quality of Life: Poor	1	10
Social Anxiety Disorder (SAD)	1	10
Stress	1	10
Sturge-Weber Syndrome	1	10
Tuberous Sclerosis	1	10
Vaccine-induced Toxicity	1	10
Breast Cancer: Triple Negative	6	9
Allodynia	4	8
Autoimmune Diseases	5	8
Endocannabinoid System	7	8
Melanoma	4	8
Middle Cerebral Artery Occlusion (MCAO)	4	8
Myocardial Infarction	3	8
Myocardial Ischemia	3	8
Traumatic Memory Formation	4	8
Colorectal Cancer	5	7
Diabetic Complications	4	7
Lymphoma	3	7
Aging: Brain	3	6
Astrocytoma: Grade IV	1	6
Emesis	1	6
Epidermolysis Bullosa	1	6
Vomiting	1	6
Acute Myeloid Leukemia	2	5
Alcoholic Liver Disease	1	5
Asthma	3	5
Brain: Oxidative Stress	2	5
Cachexia	3	5
Cancer: Pain	3	5
Chemotherapy and Radiation Toxicity	2	5
Chemotherapy-Induced Toxicity: Doxorubicin	3	5
Cholangiocarcinoma	1	5
Diabetes Mellitus: Type 1: Prevention	3	5
Drug Abuse	3	5
Gastrointestinal Inflammation	2	5
Gliomas	3	5
Leukemia	4	5
Neuroblastoma	2	5
Psychiatric Disorder: Conditioned Fear	3	5
Psychiatric Disorders	4	5
Alcohol Toxicity	2	4
Arteriosclerosis	1	4
Bladder Cancer	3	4
Brain Damage	3	4
Chemotherapy-Induced Nausea	3	4
Chemotherapy-Induced Toxicity: Oxaliplatin	1	4
Chemotherapy-Induced Toxicity: Paclitaxel	1	4
Chemotherapy-Induced Toxicity: Vincristine	1	4
Colon Cancer: Prevention	2	4
Dermatitis	1	4
Diabetes Mellitus: Type 1	2	4
Diabetes: Cataract	2	4
Endothelial Dysfunction	2	4
Endotoxemia	2	4
Eye Damage	1	4
High Fat Diet	2	4
Hypersensitivity	2	4
Iron Overload	2	4
Liver Cancer	3	4
Metabolic Syndrome X	1	4
Osteoarthritis	3	4
Pancreatic Cancer	4	4
Psychotic Disorders	3	4
Rhabdomyosarcoma	1	4
Thyroid Cancer	3	4
Acute T cell Leukemias	2	3
Aging	2	3
Allergic Airway Diseases	2	3
Arthritis	2	3
Attention Deficit Disorder with Hyperactivity	1	3
Autism	2	3
Bipolar Disorder	1	3
Drug Addiction	2	3
Encephalomyelitis	2	3
Endometrial Cancer	1	3
Epilepsy: Infant	1	3
Epilepsy: Malignant Migrating Partial Seizures	1	3
Febrile Seizures	1	3
Fibrosis	2	3
Immune Disorders	2	3
Multiple Myeloma	2	3
Psoriasis	3	3
Tremor	2	3
Acute lymphoblastic leukemia (ALL)	1	2
Alcohol Withdrawal	1	2
Amphetamine Addiction/Withdrawal	1	2
Animal Diseases: Simian Immunodeficiency Virus (SIV)	1	2
Appetite Disorders: Loss/Lack of	1	2
Bone Fractures	1	2
Brain Edema	1	2
Breast Cancer: Lung Metastasis	1	2
Breast Cancer: Metastatic	1	2
Breast Cancer: Prevention	1	2
Cachexia: Cancer	2	2
Cachexia: Chemotherapy Induced	1	2
Carcinoma: Non-Small-Cell Lung	1	2
Cardiac Arrhythmias	1	2
Cardiomyopathy	1	2
Cerebral Hypoperfusion	1	2
Cocaine Toxicity	1	2
Cough	1	2
Degenerative Disk Disease	1	2
Depression	1	2
Depressive Disorder	1	2
Dermatitis: Contact	1	2
Diabetes: Cardiovascular Illness	1	2
Diabetes: Memory Problems	1	2
Diabetes: Oxidative Stress	1	2
Diabetic Neuropathy	1	2
Diabetic Retinopathy	1	2
Drug-Induced Toxicity: Epilepsy Drugs	1	2
Epilepsy: Drug-Induced	1	2
Fatty Liver	1	2
Friedreich Ataxia	1	2
Fulminant Hepatic Failure	1	2
Gastrointestinal Diseases	1	2
Gastroschisis	1	2
Headache	2	2
Heart Attack	1	2
Hepatic Encephalopathy	1	2
Hepatitis C	2	2
Hypersensitivity: Type IV	1	2
Hypothermia	1	2
Immune Dysregulation: TH1/TH2 imbalance	1	2
Infant Neurological Development	1	2
Inflammation: Neutrophil-Mediated	1	2
Insulin Resistance	1	2
Interstitial Lung Diseases	1	2
Ischemia	1	2
Liver Damage	1	2
Liver Disease	1	2
Liver Failure: Acute	1	2
Liver Injury: Ischemia/reperfusion	1	2
Lung Inflammation	1	2
Malaria	1	2
Memory Disorders: Drug-Induced	1	2
Metabolic Diseases	1	2
Mitochondrial Dysfunction	1	2
Mood Disorders	1	2
Muscle Soreness	1	2
Myocarditis: Autoimmune	1	2
Neonatal Stroke	1	2
Neuralgia	1	2
Oral Cancer	1	2
Periodontitis	1	2
Prion Diseases	1	2
Sciatic Nerve Crush Injury	1	2
Sepsis	1	2
Spinal Cord Inflammation	1	2
Staphylococcus aureus infection	1	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	2
Tardive Dyskinesia	1	2
Traumatic Brain Injury	1	2
Urinary Bladder Diseases	1	2
Uveitis	1	2
AIDS	1	1
Acquired Immunodeficiency Syndrome	1	1
Alcohol Addiction	1	1
Anorexia	1	1
Appetite Disorders	1	1
Arthritis: Rheumatoid	1	1
Atherosclerosis	1	1
Bone Diseases	1	1
Bronchial Diseases	1	1
Cancers: Drug Resistant	1	1
Cancers: Multi-Drug Resistant	1	1
Candida Infection	1	1
Central Nervous System Diseases	1	1
Cervical Cancer	1	1
Cirrhosis	1	1
Clostridium Infections	1	1
Diabetes: Cognitive Dysfunction	1	1
Dystonia	1	1
Ebola Virus Infections	1	1
Gastric Cancer	1	1
Hepatitis	1	1
Hepatitis: Autoimmune	1	1
Herpes Simplex Virus Type 2	1	1
Herpes: Kaposi-Associated	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Influenza	1	1
Intestinal Permeability	1	1
Irritable Bowel Syndrome	1	1
Kaposi Disease	1	1
Kidney Cancer	1	1
Kidney Damage	1	1
Leishmaniasis	1	1
Leukemia: T-cell acute Lymphoblastic	1	1
Liver Fibrosis	1	1
Movement Disorders	1	1
Nausea: Chemotherapy-Induced	1	1
Oral Mucositis	1	1
Osteoporosis	1	1
Peripheral Neuropathies	1	1
Prostate: PSA Doubling	1	1
Pseudomonas aeruginosa	1	1
Rheumatoid Arthritis	1	1
Skin Diseases	1	1
Testicular Cancer	1	1
Tobacco Addiction/Withdrawal	1	1
Tumors	1	1
Ultraviolet Radiation Induced Damage	1	1

Name	AC	CK
Anti-Inflammatory Agents	108	283
Neuroprotective Agents	114	281
Anticonvulsants	39	217
Analgesics	39	205
Apoptotic	78	144
Antiproliferative	61	119
Anti-Anxiety Agents	18	73
Immunomodulatory	23	49
Tumor Necrosis Factor (TNF) Alpha Inhibitor	23	48
Antioxidants	26	47
Anti-metastatic	21	44
Angiogenesis Inhibitors	14	43
Antineoplastic Agents	26	38
Antidepressive Agents	12	37
Vasodilator Agents	5	31
Antinoceceptive	9	29
Hypoglycemic Agents	3	24
Anti-Apoptotic	12	23
Cyclooxygenase 2 Inhibitors	7	23
Antispasmodic	2	22
Vascular Endothelial Growth Factor Inhibitors	3	22
Immunosuppressive Agents	8	21
Chemotherapeutic	11	18
Anti-Tumor	9	17
Autophagy Up-regulation	9	17
Cardioprotective	8	17
NF-kappaB Inhibitor	9	16
Antihypertensive Agents	3	15
Cell cycle arrest	9	15
Chemoprotective Agents	5	15
Hepatoprotective	7	15
Interleukin-6 Downregulation	7	14
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	12
Neurogenesis	6	12
Antipsychotic Agents	7	11
Anxiolytic	2	11
Interferon Gamma Reducer	5	11
Interleukin-1 beta downregulation	6	11
Anticarcinogenic Agents	7	10
Chemopreventive	6	10
GABA Modulators	1	10
Superoxide Dismutase Up-regulation	4	10
Enzyme Inhibitors	3	9
Brain-derived neurotrophic factor modulator	4	8
Chemosensitizer	5	8
MicroRNA modulator	5	8
Nitric Oxide Inhibitor	3	8
Cannabinoid Receptor Antagonist/Inverse Agonist	3	7
P38 Mitogen-Activated Protein Kinase Modulator	2	7
Anti-Angiogenic	6	6
Vascular Cell Adhesion Molecule-1 Inhibitor	2	6
Appetite Stimulants	3	5
Hypolipidemic	1	5
Immunomodulatory: Th17 downregulation	3	5
Radiosensitizer	2	5
Anti-atherogenic	1	4
Caspase-3 Activation	3	4
Gastrointestinal Agents	3	4
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	1	4
Interleukin-10 downregulation	2	4
Interleukin-17 downregulation	3	4
Interleukin-4 downregulation	2	4
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	4
Osteoprotective	3	4
Prostaglandin PGE2 downregulation	2	4
Vascular Endothelial Growth Factor A Inhibitor	2	4
Vascular Endothelial Growth Factor Regulator	2	4
Cytotoxic	2	3
Gastroprotective	2	3
Interleukin-8 downregulation	2	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Neuritogenic	2	3
Renoprotective	2	3
Sedative effects	1	3
Vanilloid Receptor-1 Modulator	1	3
Aldose reductase inhibitor	1	2
Anti-Androgen	1	2
Anti-Bacterial Agents	2	2
Anti-Fibrotic	2	2
Calcium Channel Blockers	1	2
Catalase Up-Regulation	1	2
Cyclooxygenase Inhibitors	1	2
Enzyme Activators	1	2
Epidermal growth factor receptor (EGFR) inhibitor	1	2
Glycine Agents	1	2
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	2
Immunomodulatory: T-Cell down-regulation	1	2
Interleukin-10 upregulation	1	2
Interleukin-12 downregulation	1	2
Interleukin-2 Downregulation	1	2
Interleukin-5 downregulation	1	2
Intracellular adhesion molecule-1 (ICAM-1)	1	2
Malondialdehyde Down-regulation	1	2
Neuroplasticity enhancement	1	2
Pancreato Protective Agents	1	2
Prophylactic Agents	1	2
Redox Modulator	1	2
Topoisomerase II Inhibitor	2	2
interleukin-13 down-regulation	1	2
Acetylcholinesterase Inhibitor	1	1
Anti-Cachexic Agents	1	1
Anti-Proliferative	1	1
Anti-Psychotic	1	1
Antifungal Agents	1	1
Antiviral Agents	1	1
Caspase-8 activation	1	1
Caspase-9 Activation	1	1
Cyclooxygenase 1 Inhibitor	1	1
Interleukin-2 upregulation	1	1
NADPH Oxidase Inhibitors	1	1
Neuroimmunomodulation	1	1
Nrf2 activation	1	1
Paraptosis	1	1
Photoprotective	1	1
Transient receptor potential vanilloid type-2 activation	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1
apoptosis	1	1

[+]

Cannabinoids demonstrated antinociceptive effects in this mouse model of diabetic peripheral neuropathy.Mar 16, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FASEB J. 2003 Mar ;17(3):529-31. Epub 2003 Jan 2. PMID: 12514108

Article Published Date : Feb 28, 2003

Study Type : Animal Study

Additional Links

Substances : Cannabinoids

Diseases : Cancers: All, Gliomas

Pharmacological Actions : Angiogenesis Inhibitors, Matrix metalloproteinase-2 (MMP-2) inhibitor, Vascular Endothelial Growth Factor Regulator

Additional Keywords : Disease Regression

[+]

Cannabinoids inhibit the growth of melanoma cells but not of normal melanocytes.Nov 30, 2006

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FASEB J. 2006 Dec ;20(14):2633-5. Epub 2006 Oct 25. PMID: 17065222

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Blood. 2002 Jul 15 ;100(2):627-34. PMID: 12091357

Article Published Date : Jul 14, 2002

Study Type : Animal Study

Additional Links

Substances : Anandamide, Cannabinoids: Synthetic, Delta-tetrahydrocannabinol (THC)

Diseases : Acute lymphoblastic leukemia (ALL)

Pharmacological Actions : Anti-Tumor, Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Cannabinoid Receptors, Significant Treatment Outcome

[+]

Cannabinol may have therapeutic value in ameliorating symptoms in ALS. Sep 01, 2005

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Pubmed Data : Amyotroph Lateral Scler Other Motor Neuron Disord. 2005 Sep;6(3):182-4. PMID: 16183560

Article Published Date : Sep 01, 2005

Study Type : Animal Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Amyotrophic Lateral Sclerosis

[+]

Cannabis based medicine could be used as a neuroprotective agent capable of delaying disease progression in Huntington's disease.Aug 31, 2011

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Pubmed Data : J Neurosci Res. 2011 Sep ;89(9):1509-18. Epub 2011 Jun 14. PMID: 21674569

Pubmed Data : Mult Scler Relat Disord. 2015 Nov ;4(6):505-11. Epub 2015 Aug 5. PMID: 26590655

Article Published Date : Oct 31, 2015

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)

Additional Keywords : Plant Extracts

[+]

Cannabis extracts could be neuroprotective agents, delaying disease progression in a proinflammatory model of Huntington’s disease.May 15, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : ACS Chem Neurosci. 2012 May 16 ;3(5):400-6. Epub 2012 Feb 9. PMID: 22860209

Article Published Date : May 15, 2012

Study Type : Animal Study

Additional Links

Substances : Cannabinoids , Cannabis

Diseases : Huntington Disease, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Cannabis extracts have therapeutic potential to slow multiple sclerosis progression and repair the central nervous system.Jun 30, 2015

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Pubmed Data : Br J Pharmacol. 2015 Jul ;172(14):3579-95. Epub 2015 May 20. PMID: 25857324

Article Published Date : Jun 30, 2015

Pubmed Data : Phytother Res. 2008 Aug ;22(8):1017-24. PMID: 18618522

[+]

CBD induces antidepressant-like effects comparable to those of imipramine. Dec 31, 2009

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Pharmacol. 2010 Jan ;159(1):122-8. Epub 2009 Dec 4. PMID: 20002102

Click here to read the entire abstract

Pubmed Data : Neuropharmacology. 2013 Aug ;71:282-91. Epub 2013 Apr 12. PMID: 23587650

Article Published Date : Jul 31, 2013

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabinoids

Diseases : Brain Damage: Hypoxic Ischemic Insult, Brain Ischemia

Pharmacological Actions : Neuroprotective Agents

[+]

Neurodegenerative diseases linked directly to mitochondrial malfunction may benefit greatly from CBD-based medicines.Feb 17, 2009

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Pubmed Data : J Neurosci. 2009 Feb 18 ;29(7):2053-63. PMID: 19228959

Article Published Date : Feb 17, 2009

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Friedreich Ataxia, Huntington Disease, Mitochondrial Dysfunction , Neurodegenerative Diseases

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Oral treatment with a low dose of THC inhibits atherosclerosis progression in this mouse model.Apr 06, 2005

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Pubmed Data : Nature. 2005 Apr 7 ;434(7034):782-6. PMID: 15815632

Article Published Date : Apr 06, 2005

Study Type : Animal Study

Additional Links

Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Arteriosclerosis, Inflammation

Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents, Interferon Gamma Reducer, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Our results indicate that CBD exhibits neuroprotective effects in a cerebral malaria model and might be useful as an adjunctive therapy to prevent neurological symptoms.Mar 18, 2015

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Pubmed Data : Neuroscience. 2015 Mar 19 ;289:166-80. Epub 2015 Jan 13. PMID: 25595981

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Pubmed Data : Psychopharmacology (Berl). 2015 May 6. Epub 2015 May 6. PMID: 25943166

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2020 Mar 31 ;11(13):1141-1156. Epub 2020 Mar 31. PMID: 32284791

Article Published Date : Mar 30, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Br J Pharmacol. 2011 Aug ;163(7):1495-506. PMID: 21323909

Article Published Date : Jul 31, 2011

Study Type : Animal Study

Additional Links

Substances : Cannabinoids

Diseases : Parkinson's Disease

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Tetrahydrocannabivarin is a new potential treatment against obesity-associated glucose intolerance.Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : PLoS One. 2013 ;8(1):e54795. Epub 2013 Jan 22. PMID: 23349970

Article Published Date : Dec 31, 2012

Study Type : Animal Study

Additional Links

Substances : Cannabidiol, Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Glioblastoma Multiforme

Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic

[+]

The in vivo assessment of the role of CB receptors in inflammation and cancer might be instrumental in broadening the understanding about bladder cancer biology.Sep 30, 2015

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Pubmed Data : Life Sci. 2015 Oct 1 ;138:41-51. Epub 2014 Oct 15. PMID: 25445433

Click here to read the entire abstract

Pubmed Data : Allergy. 2013 Aug ;68(8):994-1000. Epub 2013 Jul 29. PMID: 23889474

Article Published Date : Jul 31, 2013

Study Type : Animal Study

Additional Links

Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)

Diseases : Dermatitis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2020 Aug 28 ;21(17). Epub 2020 Aug 28. PMID: 32872332

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Onco Targets Ther. 2016 ;9:4323-36. Epub 2016 Jul 18. PMID: 27486335

Click here to read the entire abstract

Pubmed Data : Cancer Chemother Pharmacol. 2017 Aug 5. Epub 2017 Aug 5. PMID: 28780725

Article Published Date : Aug 04, 2017

Study Type : Review

Additional Links

Substances : Cannabinoids

Diseases : Nausea: Chemotherapy-Induced

[+]

A review of phytochemicals and their neuroprotective effects in the treatment of dementia.Dec 31, 2015

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Pubmed Data : Molecules. 2016 ;21(4). Epub 2016 Apr 21. PMID: 27110749

A review of the promising aspects of cannabinoid-based therapies for Parkinson's disease.Dec 31, 2014

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Pubmed Data : J Cell Physiol. 2008 Mar;214(3):714-20. PMID: 17786950

Article Published Date : Mar 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Marijuana

Diseases : Arthritis: Rheumatoid, Osteoporosis

[+]

Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis.Jul 20, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Br J Pharmacol. 2013 May ;169(1):213-29. PMID: 23373571

Article Published Date : Apr 30, 2013

Study Type : In Vitro Study

Additional Links

Substances : Cannabinoids

Diseases : Colitis, Inflammation, Inflammatory Bowel Diseases, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Cannabidiol (CBD) induces functional Tregs in response to low-level T cell activation.Nov 08, 2016

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Pubmed Data : Cell Immunol. 2016 Nov 9. Epub 2016 Aug 9. PMID: 27865421

Article Published Date : Nov 08, 2016

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Pharmacological Actions : Immunosuppressive Agents

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancers (Basel). 2020 Sep 27 ;12(10). Epub 2020 Sep 27. PMID: 32992648

Article Published Date : Sep 26, 2020

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Pancreatic Cancer

Therapeutic Actions : Ozone Therapy

Pharmacological Actions : Chemotherapeutic

[+]

Cannabidiol as a novel candidate alcohol use disorder pharmacotherapy.Jan 29, 2019

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Pubmed Data : Alcohol Clin Exp Res. 2019 Jan 30. Epub 2019 Jan 30. PMID: 30698831

Article Published Date : Jan 29, 2019

Study Type : Review

Additional Links

Substances : Cannabidiol

Diseases : Alcohol Addiction

[+]

Cannabidiol as a potential treatment for psychosis.Dec 31, 2018

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Pubmed Data : Int J Cancer. 2014 Jun 1 ;134(11):2534-46. Epub 2013 Dec 2. PMID: 24293211

Article Published Date : May 31, 2014

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Multiple Myeloma

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, NF-kappaB Inhibitor

Additional Keywords : Natural Substance/Drug Synergy

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Cannabidiol can be useful in the management of oral inflammatory disorders.Sep 30, 2019

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Pubmed Data : Altern Ther Health Med. 2019 Oct 1. Epub 2019 Oct 1. PMID: 31634872

Cannabidiol induces melanogenesis through increasing MITF gene expression.Jun 06, 2017

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Pubmed Data : Chem Biol Interact. 2017 Jun 7. Epub 2017 Jun 7. PMID: 28601556

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Sci Rep. 2020 Mar 5 ;10(1):4112. Epub 2020 Mar 5. PMID: 32139776

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Pubmed Data : Int J Environ Res Public Health. 2019 Nov 12 ;16(22). Epub 2019 Nov 12. PMID: 31718076

Article Published Date : Nov 11, 2019

Cannabidiol shows great promise for the treatment of psychosis.May 27, 2016

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Pubmed Data : J Psychiatr Res. 2016 May 28 ;80:14-21. Epub 2016 May 28. PMID: 27267317

Article Published Date : May 27, 2016

Study Type : Review

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Substances : Cannabidiol

Diseases : Psychoses, Schizophrenia

Additional Keywords : Endocannabinoid System

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Cannabidiol stimulates Aml-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation.Oct 14, 2015

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Pubmed Data : Int J Cancer. 2015 Oct 15 ;137(8):1855-69. Epub 2015 May 8. PMID: 25903924

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : Plant Extracts

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Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.Nov 22, 1999

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Pubmed Data : Proc Natl Acad Sci U S A. 1999 Nov 23 ;96(24):14136-41. PMID: 10570211

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Cannabinoids are promising candidates for gastrointestinal and urinary diseases.Dec 31, 2014

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Pubmed Data : Handb Exp Pharmacol. 2015 ;231:423-47. PMID: 26408170

Article Published Date : Dec 31, 2014

Study Type : Review

Additional Links

Substances : Cannabidiol, Cannabinoids

Diseases : Gastrointestinal Diseases, Urinary Bladder Diseases

Additional Keywords : Cannabinoid Receptors

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View the Evidence: 740 Abstracts with Delta-tetrahydrocannabinol (THC) Research

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Cannabinoids demonstrated antinociceptive effects in this mouse model of diabetic peripheral neuropathy.Mar 16, 2010

Cannabinoids for the treatment of neuropsychiatric symptoms, pain and weight loss in dementia.Feb 28, 2018

Cannabinoids have anti-tumoral action against liver cancer. Sep 01, 2010

Cannabinoids inhibit the growth of gliomas in vivo by targeting both tumor cells and vascular endothelial cells.Feb 28, 2003

Cannabinoids inhibit the growth of melanoma cells but not of normal melanocytes.Nov 30, 2006

Cannabinoids may have therapeutic value in neurodegenerative conditions by preventing and/or reducing neuroinflammation. Feb 22, 2007

Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD.Feb 16, 2018

Cannabinoids seem to protect neurons against NMDA toxicity.Feb 28, 2006

Cannabinoids were effective in reducing the tumor load, prolonging the mean survival time as well as curing a significant proportion of mice in this study.Jul 14, 2002

Cannabinol may have therapeutic value in ameliorating symptoms in ALS. Sep 01, 2005

Cannabis based medicine could be used as a neuroprotective agent capable of delaying disease progression in Huntington's disease.Aug 31, 2011

Cannabis cannabinoids can achieve analgesic effects against cisplatin neuropathy.May 22, 2016

Cannabis contains a number of compounds which may have therapeutic value in delaying the progression of ALS. Mar 01, 2004

Cannabis extracts could be capable of attenuating experimental autoimmune encephalitis progression in a multiple sclerosis model. Oct 31, 2015

Cannabis extracts could be neuroprotective agents, delaying disease progression in a proinflammatory model of Huntington’s disease.May 15, 2012

Cannabis extracts have therapeutic potential to slow multiple sclerosis progression and repair the central nervous system.Jun 30, 2015

Cannabis may provide support as a novel disease-modifying therapy in ALS.Aug 31, 2014

Cannabis sativa extract attenuates diabetic neuropathic pain in rats. May 13, 2009

Cannabis sativa extract has an antihyperalgesic effect in a rat model of neuropathic pain.Jul 31, 2008

CBD administration attenuated spinal cord injury induced sublesional cancellous bone loss.May 03, 2017

CBD alleviates behavioural and gene expression alterations suggesting its potential for the management of cocaine withdrawal.Nov 22, 2020

CBD both acutely inhibited fear expression and enhanced extinction to produce longer lasting reductions in fear.Dec 31, 2015

CBD can attenuate both behavioural and dopaminergic neuronal correlates of mesolimbic dopaminergic sensitization.May 03, 2016

CBD can be considered an agent that reduces the risk of the drug relapse.Aug 31, 2017

CBD can be used as a novel therapeutic option to inhibit growth and metastasis of highly aggressive breast cancer subtypes including TNBC.Mar 31, 2015

CBD could be an interesting pharmacological approach to reduce the anxiogenic effects of stress and promote the extinction of fear memories.Nov 30, 2008

CBD exerts protective effects against Doxorubicin induced cardiotoxicity and cardiac dysfunction by attenuating oxidative and nitrative stress.Jan 05, 2015

CBD has neuroprotective effects in middle-aged diabetic rats subjected to chronic cerebral hypoperfusion.Nov 13, 2018

CBD has therapeutic potential to attenuate contextual memories associated with drugs of abuse and consequently to reduce the risk of relapse.Jan 31, 2016

CBD induced a robust increase in ROS, which led to the inhibition of cell survival, phosphorylated (p)-AKT, self-renewal and a significant increase in the survival of GSC bearing mice.Dec 31, 2014

CBD induces antidepressant-like effects comparable to those of imipramine. Dec 31, 2009

CBD leads to improvement in fracture healing and demonstrate the critical mechanical role of collagen crosslinking enzymes.Mar 18, 2015

CBD markedly improved the clinical signs of experimental autoimmune encephalomyelitis and reduced infiltration, demyelination and axonal damage.Aug 30, 2017

CBD may be beneficial for the treatment of clinical depression and other states with prominent anhedonia.Dec 31, 2015

CBD may be potent and effective at preventing the development of chemotherapy-induced peripheral neuropathy.May 25, 2017

CBD may be useful to control bone resorption during progression of experimental periodontitis in rats.Jan 31, 2009

CBD may represent a promising novel treatment for management of autoimmune myocarditis and possibly other autoimmune disordersJan 07, 2016

CBD seems to exert an anti-inflammatory and antioxidant activity favoring a faster resolution of oral mucositis.May 12, 2020

CBD treatment attenuated the development of thermal sensitivity following spinal cord injury.Mar 07, 2018

CBD's anti-inflammatory effects are linked to the inhibition of adenosine uptake.Nov 30, 2008

Co-administration of a low dose of morphine with Delta9-THC increased antinociception and 5-hydroxytryptamine levels.Jan 31, 2004

Daily treatment with topical 1 % CBD-cream may exert neuroprotective effects against autoimmune encephalomyelitis.Dec 31, 2014

Delta-tetrahydrocannabinol (THC) may modulate immune response through epigenetic regulation involving histone modifications.Jul 03, 2014

Delta-tetrahydrocannabinol, cannabidiol, and cannabichromene exert antidepressant-like actions in animal models.May 31, 2010

Distinct interactions of cannabidiol and morphine in three nociceptive behavioral models in mice.Mar 31, 2015

Effects of cannabidiol in males and females in two different rat models of depression.Dec 16, 2018

Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms.Apr 26, 2019

Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes.Oct 17, 2016

Extremely low doses of THC may provide a safe and effective treatment for cognitive decline in aging humans.Oct 05, 2017

Maternal administration of cannabidiol promotes an anti-inflammatory effect on the intestinal wall in a gastroschisis rat model.Mar 14, 2018

Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs have been identified. Jul 31, 2013

Neurodegenerative diseases linked directly to mitochondrial malfunction may benefit greatly from CBD-based medicines.Feb 17, 2009

Neuroprotective effects of the nonpsychoactive cannabinoid cannabidiol in hypoxic-ischemic newborn piglets has been observed. Nov 30, 2008

Novel insights into mitochondrial molecular targets of iron-induced neurodegeneration: Reversal by cannabidiol.Jan 28, 2018

O-1602 decreased acquisition and expression of morphine CPP and inhibited development of morphine-induced physical dependence.May 31, 2016

O-1602 is protective against experimentally induced colitis and inhibits neutrophil recruitment independently of CB1, CB2 and GPR55 receptors.Jul 31, 2011

O-1602 mediates its vasorelaxant effects partly by an endothelium-dependent pathway involving rimonabant- and O-1918-sensitive targets.Oct 14, 2015

Ondansetron and delta9-THC both dose-dependently suppressed cisplatin-induced vomiting and retching.Jun 30, 2004

Oral cannabidiol has a beneficial action on two symptoms of established inflammation: edema and hyperalgesia.Feb 29, 2004

Oral cannabidiol prevents allodynia and neurological dysfunctions in a mouse model of mild traumatic brain injury.Dec 31, 2018

Oral treatment with a low dose of THC inhibits atherosclerosis progression in this mouse model.Apr 06, 2005

Our results indicate that CBD exhibits neuroprotective effects in a cerebral malaria model and might be useful as an adjunctive therapy to prevent neurological symptoms.Mar 18, 2015

Pharmacokinetics of oral and intravenous cannabidiol and its antidepressant-like effects in chronic mild stress model.May 29, 2019

Pre or post-conditioning treatment with extremely low doses of THC before or after brain injury, may provide safe and effective long-term neuroprotection.Jun 19, 2011

Pretreatment of mice with cannabidiol attenuated the amphetamine induced disruptive effects on prepulse inhibition (PPI).May 05, 2015

Repeated administration of phytocannabinoid Delta-tetrahydrocannabinol or synthetic cannabinoids induces tolerance to hypothermia in mice.Nov 30, 2015

Short-term cannabidiol treatment results in global functional recovery in ischemic mice.Nov 22, 2016

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma.Mar 30, 2020

Tetrahdrocannabivarin has therapeutic potential for ameliorating some of the negative, cognitive and positive symptoms of schizophrenia.Feb 28, 2015

Tetrahydrocannabinol affects the glucose uptake in the rat brain.Feb 19, 2017

Tetrahydrocannabivarin could be used for delaying disease progression in PD and also for ameliorating parkinsonian symptoms.Jul 31, 2011

Tetrahydrocannabivarin is a new potential treatment against obesity-associated glucose intolerance.Dec 31, 2012

Delta-tetrahydrocannabinol (THC)

View the Evidence:
740 Abstracts with Delta-tetrahydrocannabinol (THC) Research