Carnosine

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1 Diseases Researched for Carnosine
NameACCKFocus
Autism110Locked

View the Evidence:
32 Abstracts with Carnosine Research

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Antioxidants such as carnosine and vitamin C may be effective therapies in reducing oxidative stress associated with autism. Nov 01, 2004

Pubmed Data : Altern Ther Health Med. 2004 Nov-Dec;10(6):22-36; quiz 37, 92. PMID: 15624347
Article Published Date : Nov 01, 2004
Study Type : Human Study
Additional Links
Substances : Antioxidant formulas, Carnosine, Vitamin C
Diseases : Autism
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Carnosine may modulate iron metabolism in high-risk groups which could ameliorate insulin resistance and prevent type 2 diabetes.Dec 31, 2018

Pubmed Data : Amino Acids. 2019 Jan ;51(1):73-81. Epub 2018 Aug 22. PMID: 30136029
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Carnosine
Diseases : Diabetes Mellitus: Type 2: Prevention, Insulin Resistance, Obesity
Additional Keywords : Risk Reduction
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L-carnosine protects against oxaliplatin-induced peripheral neuropathy in colorectal cancer patients.Feb 14, 2019

Pubmed Data : Toxicol Appl Pharmacol. 2019 Feb 15 ;365:41-50. Epub 2018 Dec 25. PMID: 30592963
Article Published Date : Feb 14, 2019
Study Type : Human Study
Additional Links
Substances : Carnosine
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin, Colorectal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, NF-kappaB Inhibitor, Nrf2 activation
[+]

Supplementation with alpha-lipoic acid, carnosine, and thiamine supplement effectively reduced glucose concentration in type 2 diabetic patients.Nov 30, 2018

Pubmed Data : J Med Food. 2018 Dec ;21(12):1197-1203. Epub 2018 Oct 11. PMID: 30311825
Article Published Date : Nov 30, 2018
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid, Carnosine, Thiamine (B-1)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Hypoglycemic Agents
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The use of a food supplement containing α-lipoic acid seems to bring an improvement in glycemic control and in lipid profile.Oct 27, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 Oct 28 ;17(11). Epub 2016 Oct 28. PMID: 27801825
Article Published Date : Oct 27, 2016
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid, Carnosine, Zinc
Diseases : C-Reactive Protein, Diabetes Mellitus: Type 2, Inflammation, Insulin Resistance, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypolipidemic, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
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Carnosine had chondroprotective effects on type 2 diabetes mellitus-induced osteoarthritis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:598. Epub 2018 Jun 6. PMID: 29928231
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Diabetes Mellitus: Type 2, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Chondroprotective
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Carnosine improves diabetic retinopathy via the MAPK/ERK pathway.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Apr ;17(4):2641-2647. Epub 2019 Jan 30. PMID: 30930967
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Diabetic Retinopathy
Pharmacological Actions : Cytoprotective
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Carnosine may provide neuroprotective effect after experimental intracerebral hemorrhage.Jan 31, 2017

Pubmed Data : Neurochem Res. 2017 Feb ;42(2):541-551. Epub 2016 Nov 21. PMID: 27868153
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Cerebral Hemorrhage, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
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Carnosine prevents Aβ-induced oxidative stress and inflammation in microglial cells.Jan 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2019 Jan 17 ;8(1). Epub 2019 Jan 17. PMID: 30658430
Article Published Date : Jan 16, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
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Carnosine supplementation may be a viable approach for preventing particulate matter-induced immune dysfunction and cardiovascular injury in humans.Jul 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Am Heart Assoc. 2019 Jul 2 ;8(13):e013041. Epub 2019 Jun 25. PMID: 31234700
Article Published Date : Jul 01, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Air Pollution Linked Toxicity
Pharmacological Actions : Cytoprotective
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Carnosine treatment might be considered as a therapeutic agent for peripheral nerve regeneration and its functional recovery.Dec 14, 2018

Pubmed Data : Life Sci. 2018 Dec 15 ;215:22-30. Epub 2018 Nov 1. PMID: 30391465
Article Published Date : Dec 14, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Oxidative Stress, Sciatic Nerve Crush Injury
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation, Regenerative, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Nerve Regeneration
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Combination of carnosine and asiatic acid provided greater anti-inflammatory protection for HUVE cells and diabetic mice.Feb 21, 2019

Pubmed Data : Food Chem Toxicol. 2019 Feb 22. Epub 2019 Feb 22. PMID: 30802477
Article Published Date : Feb 21, 2019
Study Type : Animal Study
Additional Links
Substances : Asiatic Acid, Carnosine
Diseases : Diabetic Complications, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance Synergy
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Effect of carnosine and α-lipoic acid on hepatocyte apoptosis and the cytokine profile in induced fatty liver disease.Dec 31, 2019

Pubmed Data : Vopr Pitan. 2020;89(5):6-16. Epub 2020 Sep 20. PMID: 33211913
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid, Carnosine
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Hepatoprotective, Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-1 alpha downregulation
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Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease.Jan 10, 2018

Pubmed Data : Mol Genet Metab. 2018 11 ;125(3):305-313. Epub 2018 Aug 10. PMID: 30146452
Article Published Date : Jan 10, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
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L-arginine and carnosine combination could effectively protect against hypoxia-induced neurotoxicity.Oct 21, 2019

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2019 Oct 22. Epub 2019 Oct 22. PMID: 31641819
Article Published Date : Oct 21, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosine, L-arginine
Diseases : Brain Hypoxia
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance Synergy
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Nutraceutical intervention reverses the negative effects of blood from aged rats on stem cellsSep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Age (Dordr). 2015 Oct ;37(5):103. Epub 2015 Sep 26. PMID: 26410618
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Blueberry, Carnosine, Green Tea, Vitamin D
Diseases : Aging
Additional Keywords : Mesenchymal Stem Cells
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Preventive effects of carnosine on lipopolysaccharide-induced lung injury.Jan 15, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 02 16 ;7:42813. Epub 2017 Feb 16. PMID: 28205623
Article Published Date : Jan 15, 2017
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
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These findings confirm effectiveness of not only preventive carnosine administration, but also its application in the postischemic period of the stroke.Sep 30, 2018

Pubmed Data : Bull Exp Biol Med. 2018 Oct ;165(6):746-750. Epub 2018 Oct 23. PMID: 30353340
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Brain Ischemia, Oxidative Stress, Stroke: Attenuation/Recovery
Pharmacological Actions : Antioxidants, Neuroprotective Agents
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Carnosine and the processes of ageing.Oct 31, 2016

Pubmed Data : Maturitas. 2016 Nov ;93:28-33. Epub 2016 Jun 22. PMID: 27344459
Article Published Date : Oct 31, 2016
Study Type : Review
Additional Links
Substances : Carnosine
Diseases : Aging, Inflammation, Oxidative Stress
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Carnosine as an effective neuroprotector in brain pathology and potential neuromodulator in normal conditions.Dec 31, 2018

Pubmed Data : Amino Acids. 2019 Jan ;51(1):139-150. Epub 2018 Oct 23. PMID: 30353356
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Carnosine
Diseases : Brain Damage
Pharmacological Actions : Neuroprotective Agents
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Carnosine exhibits significant antiviral activity against Dengue and Zika virus.Jul 08, 2019

Pubmed Data : J Pept Sci. 2019 Jul 9:e3196. Epub 2019 Jul 9. PMID: 31290226
Article Published Date : Jul 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Dengue, Zika Virus
Pharmacological Actions : Antiviral Agents
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Carnosine has a promising potential for the treatment and prevention of different kidney diseases.Jul 29, 2019

Pubmed Data : Curr Med Chem. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31362685
Article Published Date : Jul 29, 2019
Study Type : Review
Additional Links
Substances : Carnosine
Diseases : Chronic Kidney Disease (CKD), Diabetic Nephropathy, Kidney Damage: Chemically-Induced
Pharmacological Actions : Renoprotective
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Carnosine increases efficiency of temozolomide and irradiation treatment of isocitrate dehydrogenase-wildtype glioblastoma cells in culture.Oct 29, 2019

Pubmed Data : Future Oncol. 2019 Oct 30. Epub 2019 Oct 30. PMID: 31664860
Article Published Date : Oct 29, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Glioblastoma
Pharmacological Actions : Antiproliferative , Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Temozolomide
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Carnosine induces intestinal cells to secrete exosomes that activate neuronal cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(5):e0217394. Epub 2019 May 28. PMID: 31136600
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuritogenic, Neuroprotective Agents
Additional Keywords : Exosomes, Gut-brain Axis
[+]

Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(6):e0218972. Epub 2019 Jun 27. PMID: 31247000
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Glioblastoma
Pharmacological Actions : Antiproliferative
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Carnosine protects cardiac myocytes against lipid peroxidation products.Dec 31, 2018

Pubmed Data : Amino Acids. 2019 Jan ;51(1):123-138. Epub 2018 Nov 17. PMID: 30449006
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Lipid Peroxidation
Pharmacological Actions : Antioxidants
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Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Cell Int. 2018 ;18:111. Epub 2018 Aug 13. PMID: 30123089
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Glioblastoma
Pharmacological Actions : Anti-metastatic, Antiproliferative
Additional Keywords : Selective Antiproliferation
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Carnosine suppresses human colorectal cell migration and intravasation.Dec 31, 2018

Pubmed Data : Am J Chin Med. 2019 ;47(2):477-494. PMID: 30909731
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Cancer Metastasis, Colorectal Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor
[+]

Carnosine's inhibitory effect on glioblastoma cell growth is independent of its cleavage.Apr 30, 2019

Pubmed Data : Amino Acids. 2019 May ;51(5):761-772. Epub 2019 Mar 12. PMID: 30863889
Article Published Date : Apr 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Glioblastoma
Pharmacological Actions : Antiproliferative , Cell cycle arrest
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Pivotal role of carnosine in the modulation of brain cells activity.Dec 25, 2018

Pubmed Data : Prog Neurobiol. 2018 Dec 26. Epub 2018 Dec 26. PMID: 30593839
Article Published Date : Dec 25, 2018
Study Type : Review
Additional Links
Substances : Carnosine
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Studies suggest carnosine as a promising therapeutic agent in brain disorders.May 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2019 May 28 ;11(6). Epub 2019 May 28. PMID: 31141890
Article Published Date : May 27, 2019
Study Type : Review
Additional Links
Substances : Carnosine
Diseases : Neurodegenerative Diseases, Psychiatric Disorders
Pharmacological Actions : Neuroprotective Agents
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The current findings demonstrate that carnosine protects MPC5 cell against high glucose-induced apoptosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:4348973. Epub 2019 May 28. PMID: 31275971
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Carnosine
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation

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