Astaxanthin

Name	AC	CK
Oxidative Stress	68	167
Athletic Performance	6	44
Inflammation	20	44
Cognitive Decline/Dysfunction	11	43
Lipid Peroxidation	13	39
Diabetes Mellitus: Type 2	9	33
Obesity	8	31
Alzheimer's Disease	18	26
Muscle Damage: Exercise-Induced	3	22
Ultraviolet Radiation Induced Damage	9	22
Aging Skin	3	21
Immune Disorders: Low Immune Function	3	21
Helicobacter Pylori Infection	8	20
Overweight	2	20
Diabetic Complications	10	17
Aging	9	15
Alcohol Toxicity	9	15
Infertility: Male	4	15
Memory Disorders	4	15
Brain Inflammation	8	14
Cardiovascular Diseases	11	14
Diabetic Nephropathy	8	14
High Fat Diet	7	14
Lipopolysaccharide-Induced Toxicity	8	14
Macular Degeneration	3	13
Cerebral Ischemia	7	12
Hypertension	6	12
Insulin Resistance	7	12
Kidney Damage	7	12
Nonalcoholic fatty liver disease (NAFLD)	8	12
Acid Reflux	2	11
Brain: Oxidative Stress	6	11
Liver Fibrosis	7	11
Smoking	2	11
AST: Elevated	1	10
Apolipoprotein A/B ratio imbalances	1	10
Atherosclerosis	6	10
Cholesterol: LDL/HDL ratio	1	10
Creatine Phosphokinase (CK): Elevated	1	10
Diabetes: Oxidative Stress	5	10
Eye Diseases: Lack of Blood Circuation	1	10
Heart Failure	1	10
Liver Cancer	7	10
Low Testosterone	1	10
Male Hormone Imbalances	1	10
Menopausal Syndrome	1	10
Mental Fatigue	1	10
Parkinson's Disease	9	10
Testosterone: Too Low	1	10
Breast Cancer	8	9
Chemotherapy-Induced Toxicity: Cisplatin	5	9
Colon Cancer	6	9
DNA damage	5	9
Atopic Dermatitis	4	8
Muscle Atrophy	4	8
Wound Healing	5	8
Cancers: All	6	7
Chemotherapy and Radiation Toxicity	2	7
Diabetes Mellitus: Type 1	4	7
Diabetic Retinopathy	6	7
Fatty Liver	4	7
Neurodegenerative Diseases	7	7
Alcoholic Liver Disease	3	6
Brain Injury: Traumatic	3	6
Burns	3	6
Chemotherapy-Induced Toxicity: Cyclophosphamide	3	6
Depression	3	6
Gastric Ulcer	3	6
Glaucoma	4	6
High Fructose Diet	3	6
Kidney Fibrosis	3	6
Lung Injury: Acute	3	6
Mitochondrial Dysfunction	4	6
Prostate Cancer	5	6
Spinal Cord Injuries	3	6
Subarachnoid hemorrhage	3	6
Advanced Glycation Endproduct (AGE) Formation	1	5
Aging: Brain	3	5
Hypoxia	3	5
Liver Damage	4	5
Myocardial Fibrosis	1	5
Neutrophils: Damaged	1	5
Oral Cancer	3	5
Oral Lichen Planus	1	5
Asthma	3	4
Chemotherapy-Induced Toxicity: Doxorubicin	2	4
Cholesterol: Oxidation	2	4
Diabetes: Cardiovascular Illness	2	4
Endothelial Dysfunction	2	4
Epilepsy	2	4
Fructose-Induced Toxicity	2	4
Glioblastoma	3	4
Ischemia	2	4
Liver Damage: Drug-Induced	2	4
Metabolic Syndrome X	2	4
Multiple Sclerosis	2	4
Myocardial Ischemia	3	4
Osteoarthritis	3	4
Pancreatitis	2	4
Photokeratitis	2	4
Sepsis	2	4
Stroke: Prevention	2	4
Traumatic Brain Injury	2	4
Arthritis	2	3
Cataract	2	3
Colorectal Cancer	2	3
Dementia	2	3
Diabetes: Cognitive Dysfunction	2	3
Esophageal Cancer	2	3
Fibrosis	2	3
Homocysteine: Elevated	2	3
Hydrogen Peroxide Induced Toxicity	3	3
Pre-Eclampsia	2	3
Stroke	2	3
Xenobiotic Exposures	2	3
Acetaminophen (Tylenol) Toxicity	1	2
Aflatoxicosis	1	2
Agent Orange Toxicity	1	2
Allergic Airway Diseases	1	2
Aluminum Toxicity	1	2
Arterial Hardening: Elasticity	1	2
Aspirin-Induced Toxicity	1	2
Autoimmune Diseases	1	2
Bisphenol Toxicity	1	2
Blood Pressure: High	1	2
Brain Ischemia	1	2
Breast Cancer: Prevention	1	2
C-Reactive Protein	1	2
Cachexia	1	2
Cancer Metastasis	1	2
Carcinoma: Non-Small-Cell Lung	2	2
Cardiomyopathy	1	2
Chemically-Induced Liver Damage	1	2
Chronic Obstructive Pulmonary Disease	1	2
Coenzyme Q10 Deficiency	1	2
Colitis	1	2
Dental Caries	1	2
Dental Diseases	1	2
Diabetes: Cataract	1	2
Diabetes: Dental Problems	1	2
Diabetes: Immune Problems	1	2
Drug-Induced Toxicity: Methotrexate	1	2
Dry Eye Syndromes	2	2
Dyslipidemias	1	2
Exercise-Induced Tissue Damage	1	2
Eye Diseases	2	2
Fibrosarcoma	1	2
Gastric Cancer	2	2
Gestational Diabetes	1	2
Hepatic Steatosis	1	2
High Cholesterol	1	2
High Homocysteine	1	2
High Sugar Diet	1	2
Hyperhomocysteinemia	1	2
Hyperuricemia	1	2
Immune Dysregulation: TH1 dominance	1	2
Infertility: Female	1	2
Intima Media Thickening	1	2
Intraocular hypertension	1	2
Keratitis	1	2
Kidney Damage: Chemically-Induced	1	2
Kidney Damage: Drug-Induced	1	2
Liver Damage: Aflatoxin-Induced	1	2
Liver Injury: Ischemia/reperfusion	1	2
Low Immune Function: Splenic Dysfunction	1	2
Lung Cancer	2	2
Lung Damage	1	2
Lymphadenopathy	1	2
Mastocytoma	1	2
Memory Loss	1	2
Mercury Poisoning	1	2
Middle Cerebral Artery Occlusion (MCAO)	1	2
Miscarriage	1	2
Myocardial Infarction	1	2
Necrotising enterocolitis	1	2
Neuropathic Pain	1	2
Osteopenia	1	2
Osteoporosis	1	2
Pancreatic Cancer	1	2
Periodontal Diseases	1	2
Periodontitis	1	2
Pesticide Toxicity	1	2
Polycystic Ovary Syndrome	1	2
Pregnancy Complications	1	2
Prenatal Chemical Exposures	1	2
Proteinuria	1	2
Pruritus	1	2
Radiation Induced Illness	1	2
Radiation Induced Illness: Bone Marrow	1	2
Retinal Diseases	1	2
Retinopathy: Hyperoxia-induced	1	2
Seizures	1	2
Skin Cancer	1	2
Skin Diseases	2	2
Sperm Quality: Low	1	2
Spinal Cord Inflammation	1	2
Squamous cell carcinoma	1	2
Stress	1	2
Stroke: Ischemic	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Thrombosis	1	2
Tobacco Toxicity	1	2
Triglycerides: Elevated	1	2
Vascular Dementia	1	2
Vitamin A Deficiency	1	2
Weight Problems	1	2
Advanced Glycation End products (AGE)	1	1
Air Pollution Linked Toxicity	1	1
Alzheimer's Disease: Homocysteine Associated	1	1
Autism	1	1
Blue Light Toxicity	1	1
Cardiac Failure	1	1
Chronic Kidney Disease (CKD)	1	1
Copper Toxicity	1	1
Coronavirus Infection	1	1
Dopamine Toxicity	1	1
Dry Skin	1	1
Endometritis	1	1
Gastrointestinal Diseases	1	1
Glomerulosclerosis	1	1
Hearing Loss	1	1
Human Papillomavirus (HPV)	1	1
Inflammatory Bowel Diseases	1	1
Iron Overload	1	1
Iron Poisoning	1	1
Lead Poisoning	1	1
Leukemia	1	1
Liver Disease	1	1
Lung Diseases	1	1
Melanoma	1	1
Mitochondrial Diseases	1	1
Neurological Conditions	1	1
Neurotoxicity	1	1
Pulmonary Fibrosis	1	1
Skin Diseases: Photo-Aging	1	1
Sunburn	1	1
Vascular Calcification	1	1

Name	AC	CK
Antioxidants	177	407
Anti-Inflammatory Agents	84	162
Neuroprotective Agents	75	135
Anti-Apoptotic	42	64
Tumor Necrosis Factor (TNF) Alpha Inhibitor	22	54
Cardioprotective	24	48
Interleukin-6 Downregulation	20	45
NF-kappaB Inhibitor	21	45
Hepatoprotective	25	43
Nrf2 activation	23	38
Apoptotic	22	37
Interleukin-1 beta downregulation	19	36
Superoxide Dismutase Up-regulation	11	35
Antiproliferative	21	28
Hypolipidemic	11	28
Photoprotective	8	28
Renoprotective	16	28
Regenerative	6	27
Heme oxygenase-1 up-regulation	16	25
Anti-Fibrotic	10	21
Chemopreventive	11	21
Antihypertensive Agents	6	19
MicroRNA modulator	6	18
Hypoglycemic Agents	5	17
Immunostimulatory	4	15
Chemoprotective Agents	7	14
Radioprotective	4	14
Immunomodulatory	7	13
Anticarcinogenic Agents	6	12
Cyclooxygenase 2 Inhibitors	7	12
Malonaldehyde (MDA) Down-Regulation	2	12
Malondialdehyde Down-regulation	6	12
Adiponectin upregulation	1	10
Aromatase Inhibitors	1	10
Ergogenic	1	10
Isoprostane Down-Regulation	1	10
Cytoprotective	5	9
Gastroprotective	4	8
Anti-metastatic	5	7
Catalase Up-Regulation	4	7
Cell cycle arrest	6	7
Genoprotective	2	7
Insulin Sensitizers	4	7
Gastrointestinal Agents	4	6
Glutathione Upregulation	3	6
Anti-atherogenic	3	5
Chemosensitizer	4	5
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	3	5
Osteoprotective	3	5
Angiogenesis Inhibitors	2	4
Antidepressive Agents	2	4
Bcl-2 protein down-regulation	3	4
Glutathione Peroxidase 1 (GPx1) Up-Regulation	2	4
Hypotensive	2	4
Interleukin-4 downregulation	2	4
Nitric Oxide Inhibitor	2	4
Pancreato Protective Agents	2	4
STAT3 Inhibitor	3	4
Tumor Suppressor Protein p53 Upregulation	2	4
Brain-derived neurotrophic factor modulator	2	3
Detoxifier	2	3
Fertility Agents: Male	2	3
Interleukin-8 downregulation	3	3
Matrix metalloproteinase-1 (MMP-1) inhibitor	2	3
Matrix metalloproteinase-3 (MMP-3) inhibitor	2	3
Angiotensin-Converting Enzyme Inhibitors	1	2
Anti-Adipogenic	1	2
Anti-Asthmatic Agents	1	2
Anti-Ulcer Agents	1	2
Anti-thrombotic	1	2
Anticholesteremic Agents	1	2
Antineoplastic Agents	2	2
Antioxidant	1	2
Anxiolytic	1	2
Chemotherapeutic	2	2
Interferon-gamma (IFN-gamma) inducer	1	2
Interleukin-10 upregulation	1	2
Interleukin-5 downregulation	1	2
Lipoxygenase Inhibitors	1	2
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	2
Neurogenesis	1	2
Prophylactic Agents	1	2
Redox Balancer	1	2
Uricosuric Agents	1	2
Vascular Endothelial Growth Factor Inhibitors	1	2
Xanthine oxidase inhibitor	1	2
apoptosis	1	2
5-alpha reductase inhibitor	1	1
Anti-Proliferative	1	1
Autophagy Up-regulation	1	1
Bax/Bcl2 ratio: Increase	1	1
Cytotoxic	1	1
Enzyme Inhibitors	1	1
Erk/MAP Inactivation	1	1
Histone deacetylase inhibitor	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
P38 Mitogen-Activated Protein Kinase Modulator	1	1
Prostaglandin PGE2 downregulation	1	1
Radiosensitizer	1	1
Receptor activator of NF-κB (RANK) gene expression	1	1

[+]

Supplementation of astaxanthin in the diet has positive effects on symptoms associated with obesity related diseases.May 07, 2021

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Pubmed Data : Free Radic Biol Med. 2021 May 8. Epub 2021 May 8. PMID: 33974978

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Pubmed Data : J Med Food. 2011 Sep 1. Epub 2011 Sep 1. PMID: 21883001

Article Published Date : Sep 01, 2011

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Pubmed Data : Int J Sports Med. 2011 Oct 7. Epub 2011 Oct 7. PMID: 21984399

Article Published Date : Oct 07, 2011

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Athletic Performance

Pharmacological Actions : Ergogenic

[+]

Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly.May 31, 2021

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Pubmed Data : Physiol Rep. 2021 Jun ;9(11):e14887. PMID: 34110707

Pubmed Data : Biosci Biotechnol Biochem. 2009 Sep;73(9):1928-32. Epub 2009 Sep 7. PMID: 19734684

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Additional Keywords : Plant Extracts

[+]

Cognitive function improvement with astaxanthin and tocotrienol intake.Oct 31, 2020

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Pubmed Data : J Clin Biochem Nutr. 2017 Jul ;61(1):33-39. Epub 2017 Jun 20. PMID: 28751807

Article Published Date : Jun 30, 2017

Study Type : Human Study

Additional Links

Substances : Astaxanthin

Diseases : Aging Skin

Pharmacological Actions : Anti-Inflammatory Agents, Photoprotective

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Safety Study: 6 mg of astaxanthin a day is associated with no adverse effects in humans. Jan 01, 2003

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Pubmed Data : Avicenna J Med Biotechnol. 2018 Apr-Jun;10(2):69-74. PMID: 29849982

Article Published Date : Apr 01, 2018

Study Type : Human In Vitro

Additional Links

Substances : Astaxanthin

Pharmacological Actions : Regenerative

Additional Keywords : Nerve Regeneration

[+]

Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles.Jan 01, 2019

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A combination of flaxseed oil and astaxanthin may reduce NAFLD by reversing hepatic steatosis and reducing lipid accumulation and oxidative stress.Mar 12, 2017

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Pubmed Data : Nutrients. 2017 Mar 13 ;9(3). Epub 2017 Mar 13. PMID: 28335388

Article Published Date : Mar 12, 2017

Study Type : Animal Study

Additional Links

Substances : Astaxanthin, Flaxseed Oil

Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD), Oxidative Stress

Pharmacological Actions : Antioxidants, Hepatoprotective, Hypolipidemic

[+]

Absorbability of astaxanthin was much lower in obese mice than in normal mice.Sep 22, 2020

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Pubmed Data : J Agric Food Chem. 2020 Sep 23. Epub 2020 Sep 23. PMID: 32914625

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Pubmed Data : Biochim Biophys Acta. 1999 Jan 4;1426(1):119-25. PMID: 9878705

Article Published Date : Jan 04, 1999

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants

[+]

An astaxanthin extract appears to mitigate the progression of atherosclerosis in the animal model. Jul 06, 2011

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Pubmed Data : J Nutr. 2011 Jul 6. Epub 2011 Jul 6. PMID: 21734060

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Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:8894491. Epub 2021 Jan 5. PMID: 33505592

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Inflammation

Pharmacological Actions : Gastrointestinal Agents, Gastroprotective

Problem Substances : Ochratoxin A

[+]

Astaxanthin alleviates pathological brain aging through the upregulation of hippocampal synaptic proteins.May 31, 2021

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Pubmed Data : Life Sci. 2007 Jan 16;80(6):522-9. Epub 2006 Oct 12. PMID: 17074368

Article Published Date : Jan 16, 2007

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Metabolic Syndrome X

[+]

Astaxanthin ameliorates ischemic-hypoxic-induced neurotrophin receptor p75 upregulationDec 05, 2019

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Pubmed Data : Int J Mol Sci. 2019 Dec 6 ;20(24). Epub 2019 Dec 6. PMID: 31817750

Article Published Date : Dec 05, 2019

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Stroke: Ischemic

Pharmacological Actions : Neuroprotective Agents

[+]

Astaxanthin ameliorates lipopolysaccharide-induced neuroinflammation, oxidative stress and memory dysfunction.Feb 17, 2019

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Pubmed Data : BMC Neurosci. 2016 ;17(1):11. Epub 2016 Feb 8. PMID: 26856812

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress, Prenatal Chemical Exposures

Pharmacological Actions : Antioxidants

[+]

Astaxanthin ameliorates the lipopolysaccharides-induced subfertility.Jun 30, 2019

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[+]

Astaxanthin attenuates oxidative stress and inflammatory responses in complete Freund-adjuvant-induced arthritis.Jan 31, 2020

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Pubmed Data : Pharmacol Rep. 2020 Feb ;72(1):104-114. Epub 2019 Dec 19. PMID: 32016833

Article Published Date : Jan 31, 2020

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Arthritis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Astaxanthin can be a potential option for slowing the progression of Alzheimer's disease.Apr 27, 2021

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Astaxanthin had a significant protective effect on liver fibrosis by suppressing multiple pro-fibrogenic factors.Dec 31, 2013

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Pubmed Data : Mediators Inflamm. 2014 ;2014:954502. Epub 2014 Apr 17. PMID: 24860243

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic

[+]

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Astaxanthin improves cognitive deficits from oxidative stress in diabetes rats.Dec 31, 2014

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Pubmed Data : Biochem Biophys Res Commun. 2008 Feb 22;366(4):892-7. Epub 2007 Dec 17. PMID: 18082622

Article Published Date : Feb 22, 2008

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Athletic Performance, Weight Problems

[+]

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

Astaxanthin inhibits Helicobacter pylori-induced inflammatory and oncogenic responses in gastric mucosal tissues.Dec 29, 2020

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Pubmed Data : IUBMB Life. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31251469

Article Published Date : Jun 27, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Astaxanthin

Diseases : Oral Cancer, Squamous cell carcinoma

Pharmacological Actions : Angiogenesis Inhibitors, Anticarcinogenic Agents, Antiproliferative , Apoptotic

[+]

Astaxanthin intake attenuates muscle atrophy caused by immobilization in rats.Dec 31, 2015

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Astaxanthin may be benefit for prevention and treatment of preeclampsia disease.Sep 30, 2014

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Pubmed Data : Yao Xue Xue Bao. 2014 Oct ;49(10):1400-5. PMID: 25577869

Article Published Date : Sep 30, 2014

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Pre-Eclampsia

Pharmacological Actions : Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation

[+]

Astaxanthin may be used as a preventive or therapeutic approach for co-morbidity of diabetes and depression.Dec 31, 2018

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Pubmed Data : Front Pharmacol. 2019 ;10:1621. Epub 2020 Jan 30. PMID: 32082151

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Pubmed Data : Brain Res Bull. 2017 Feb 1. Epub 2017 Feb 1. PMID: 28161193

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Cerebral Ischemia

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Astaxanthin may have therapeutic potential for treating asthma.Nov 20, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Jan 01, 2000

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Fibrosarcoma

Pharmacological Actions : Chemopreventive, Immunostimulatory, Interferon-gamma (IFN-gamma) inducer

[+]

Astaxanthin prevents fish-oil induced oxidative stress in the anterior forebrain of animals, resulting in an anxiety reducing effect. May 17, 2011

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Pubmed Data : Pharmacol Biochem Behav. 2011 May 17;99(3):349-355. Epub 2011 May 17. PMID: 21619892

Article Published Date : May 17, 2011

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidants, Anxiolytic, Neuroprotective Agents

[+]

Astaxanthin prevents fructose-induced adverse changes in insulin signaling and inflammation in obese rats.Nov 17, 2011

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Pubmed Data : Food Funct. 2011 Nov 17. Epub 2011 Nov 17. PMID: 22089895

Article Published Date : Nov 17, 2011

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Pubmed Data : Sci Rep. 2017 Jan 27 ;7:41440. Epub 2017 Jan 27. PMID: 28128352

Article Published Date : Jan 26, 2017

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Burns, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

[+]

Astaxanthin protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced liver injury in rats.Feb 06, 2012

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Pubmed Data : Toxicol Ind Health. 2012 Feb 6. Epub 2012 Feb 6. PMID: 22312033

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Pubmed Data : Mar Drugs. 2021 Jun 17 ;19(6). Epub 2021 Jun 17. PMID: 34204220

Article Published Date : Jun 16, 2021

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Immunomodulatory, Nrf2 activation

[+]

Astaxanthin protects ochratoxin -induced lung injury in mice through the Nrf2/NF-κB pathway.Sep 16, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Oct 05, 2011

Study Type : Animal Study

Additional Links

Substances : Astaxanthin, Fish Oil

Diseases : Oxidative Stress

Pharmacological Actions : Immunomodulatory, Interleukin-1 beta downregulation

Additional Keywords : Natural Substance Synergy

[+]

Astaxanthin reduces traumatic brain injury-related injury in brain tissue.Dec 31, 2015

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Pubmed Data : Onco Targets Ther. 2019 ;12:5087-5096. Epub 2019 Jul 1. PMID: 31308688

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Esophageal Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor

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[+]

Astaxanthin suppresses cigarette smoke-induced emphysema through Nrf2 activation.Nov 27, 2019

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Pubmed Data : Mar Drugs. 2019 Nov 28 ;17(12). Epub 2019 Nov 28. PMID: 31795292

Article Published Date : Nov 27, 2019

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Chronic Obstructive Pulmonary Disease, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Nrf2 activation

[+]

Astaxanthin suppresses lipopolysaccharide‑induced myocardial injury.Aug 18, 2020

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Pubmed Data : Chem Biol Interact. 2018 Jan 5 ;279:145-158. Epub 2017 Nov 24. PMID: 29179950

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Pubmed Data : PLoS One. 2015 ;10(8):e0134733. Epub 2015 Aug 11. PMID: 26262684

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : High Fat Diet

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation

[+]

High dose astaxanthin compares favorably to the drugs captopril and pioglitazone at lowering blood pressure, increasing insulin sensitivity and reducing restraint stress. Jan 01, 2011

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Pubmed Data : Int J Med Sci. 2011;8(2):126-38. Epub 2011 Feb 9. PMID: 21326955

Article Published Date : Jan 01, 2011

Study Type : Animal Study

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Substances : Astaxanthin

Diseases : Hypertension, Insulin Resistance, Stress

Pharmacological Actions : Hypotensive, Insulin Sensitizers

Additional Keywords : Drug: Captopril, Drug: Pioglitazone, Superiority of Natural Substances versus Drugs

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Improved anti-inflammatory effects of liposomal astaxanthin on a phthalic anhydride-induced atopic dermatitis model.Dec 31, 2019

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Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:4946902. Epub 2020 Aug 3. PMID: 32832000

Therapeutic potential of astaxanthin in diabetic kidney disease.Dec 31, 2020

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Pubmed Data : Adv Exp Med Biol. 2021 ;1261:239-248. PMID: 33783747

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Diabetic Nephropathy, Oxidative Stress

Pharmacological Actions : Renoprotective

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These findings suggest that astaxanthin is beneficial for boosting reverse cholesterol transport and preventing the development of atherosclerosis.Dec 31, 2016

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Pubmed Data : Curr Eye Res. 2016 11 ;41(11):1465-1472. Epub 2016 May 9. PMID: 27158842

Article Published Date : Jan 10, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Astaxanthin

Diseases : Ischemia, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants

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These results indicate the potential health-promoting effects of fucoxanthin in skin cancer prevention.Jan 19, 2018

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Pubmed Data : Molecules. 2016 ;21(3). Epub 2016 Mar 19. PMID: 27007359

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Pubmed Data : FASEB J. 2020 Jul 10. Epub 2020 Jul 10. PMID: 32648603

Article Published Date : Jul 09, 2020

Study Type : In Vitro Study

Additional Links

Substances : Astaxanthin

Diseases : Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation

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Supplementation of astaxanthin in the diet has positive effects on symptoms associated with obesity related diseases.May 07, 2021

The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial Jul 02, 2020

A combination of nutrients improves age-related macular degeneration. Feb 01, 2008

A dietary supplement containing astaxanthin and saw palmetto berry extract decrease dihydrotestosterone, increase testosterone and decrease estradiol levels in healthy males. Sep 01, 2009

A formula containing calcium, vitamin D3, lycopene , astaxantin and citrus bioflavonoids reducing climacteric symptoms in menopausal women. Jun 01, 2010

Astaxanthin addition improves human neutrophils function.Dec 01, 2010

Astaxanthin and sesamin supplementation may be a candidate to promote recovery from mental fatigue.Feb 27, 2018

Astaxanthin derived from Haematococcus pluvialis improves the skin condition in both women and men.Mar 17, 2012

Astaxanthin has a positive effect on lipid profiles and oxidative stress in overweight subjects. Oct 01, 2011

Astaxanthin has antioxidant properties in soccer players.Nov 27, 2012

Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus.Dec 31, 2017

Astaxanthin improves human sperm capacitation by inducing lyn displacement and activation.Aug 24, 2015

Astaxanthin improves oxidative stress in overweight and obese adults. Apr 08, 2011

Astaxanthin increases blood flow in the eyes as measured by increased choroidal blood flow velocity.Nov 10, 2011

Astaxanthin prevents in vitro auto-oxidative injury in human lymphocytes.Oct 01, 2010

Astaxanthin protects smokers against oxidative stress. Sep 01, 2011

Astaxanthin reduces reflux symptoms in patients, especially in those with pronounced H. pylori infection.Jun 01, 2008

Astaxanthin seems protective against UV-induced skin deterioration and helps maintain healthy skin in healthy people.Jun 24, 2018

Astaxanthin significantly improves athletic performance as measured by cycling time. Oct 07, 2011

Astaxanthin supplementation enhances metabolic adaptation with aerobic training in the elderly.May 31, 2021

Astaxanthin supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training.Dec 31, 2014

Astaxanthin supplementation may have a beneficial effect on muscle damage and oxidative stress markers in atheletes. Jul 31, 2012

Astaxanthin supplementation reduces lipid peroxidation. Jan 01, 2007

Astaxanthin supplementation results in measurable improvement in the antioxidant status of human subjects. Jan 01, 2011

Astaxanthin, β-carotene, and resveratrol-rich foods support resistance training-induced adaptation.Jan 13, 2021

Astaxanthin-rich Haematococcus pluvialis extract improves cognitive function in the healthy aged individuals.Aug 31, 2012

Bioavailability Study: Administration After-Meal Significantly Improves Availability. Sep 01, 2009

Cognitive function improvement with astaxanthin and tocotrienol intake.Oct 31, 2020

Continuous astaxanthin consumption produces a strong antioxidant effect resulting in facial skin rejuvenation.Nov 30, 2017

Following 3-month astaxanthin supplementation, suppressed oxidative stress and improved cardiac contractility and exercise tolerance.Jun 25, 2020

Long-term prophylactic astaxanthin supplementation may inhibit age-related skin deterioration.Jun 30, 2017

Safety Study: 6 mg of astaxanthin a day is associated with no adverse effects in humans. Jan 01, 2003

The antioxidant and anti-inflammatory effects of astaxanthin supplementation on the expression of miR-146a and miR-126 in patients with type 2 diabetes mellitus.Jan 13, 2021

These results provide support for the use of astaxanthin and sesamin as a dietary supplementation for improving cognitive functions.Dec 31, 2017

Astaxanthin could be useful for improving chronic inflammation such as that associated with oral lichen planus.Apr 30, 2015

Astaxanthin enhances adipose-derived mesenchymal stem cell proliferation in vitro.Jul 29, 2019

Astaxanthin improves stem cell potency via an increase in the proliferation of neural progenitor cells.Jan 01, 2010

Astaxanthin improves the proliferative capacity as well as the osteogenic and adipogenic differentiation potential in neural stem cells.Jun 01, 2010

Astaxanthin may be useful as a preventive/therapeutic agent for cardiac dysfunction and myocardial fibrosis.Mar 11, 2017

Astaxanthin modifies clastogenic effects of ionizing radiation in vitro in peripheral blood lymphocytes.Nov 30, 2016

Astaxanthin promotes the differentiation of human adipose-derived mesenchymal stem cells into oligodendrocyte precursor cells.Apr 01, 2018

Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles.Jan 01, 2019

The antioxidants astaxanthin and vitamin C promoted a significant improvement in the function of neutrophils and in the redox status.Jun 28, 2012

These results obtained testify the powerful radioprotective potential of astaxanthin.Nov 30, 2016

Astaxanthin alleviates oxidative damage in acute pancreatitis via direct antioxidant mechanisms.Sep 30, 2020

"Astaxanthin inhibits thrombosis in cerebral vessels of stroke-prone spontaneously hypertensive rats."Oct 01, 2011

A calorie restricted diet and carotenoids delay the onset of symptoms of lymphadenopathy and proteinuria in mice. Jan 01, 1993

A combination of astaxanthin and fish oil supplementation alters antioxidant enzyme profile of dental pulp tissue.May 06, 2012

A combination of astaxanthin, Ginkgo biloba and vitamin C is equal to or better than ibuprofen for reducing asthma-associated respiratory inflammation.Jan 01, 2011

A combination of flaxseed oil and astaxanthin may reduce NAFLD by reversing hepatic steatosis and reducing lipid accumulation and oxidative stress.Mar 12, 2017

Absorbability of astaxanthin was much lower in obese mice than in normal mice.Sep 22, 2020

Alpha-tocopherol and astaxanthin have anti-atherogenic properties. Nov 01, 2004

Ameliorative effects of astaxanthin on brain tissues of alzheimer's disease-like model.Feb 10, 2021

An astanxanthin rich red yeast reduces oxidative stress in rainbow trout. Jan 04, 1999

An astaxanthin extract appears to mitigate the progression of atherosclerosis in the animal model. Jul 06, 2011

An astaxanthin-rich algal powder improves memory in mice. Dec 01, 2007

An essential amino acid, omega-3 fatty acid and asthaxanthin rich crayfish extract reduces symptoms of cachexia and improves survival in rats with cancer.Sep 01, 2007

Anti-diabetic effects of astaxanthin on an STZ-induced diabetic model in rats.Dec 01, 2020

Anti-hyperuricemic effects of astaxanthin by regulating xanthine oxidase, adenosine deaminase and urate transporters.Nov 30, 2020

Anti-inflammatory effects of astaxanthin against fungal keratitis Dec 31, 2019

Antioxidant therapy probects against non-alcoholic fatty liver disease. Jul 15, 2011

Antiproliferative and anti-apoptotic effect of astaxanthin in an oxygen-induced retinopathy model.Jan 31, 2019

Asaxanthin prevents mammary tumor initiation, but may be contradicted after tumor initiation. Jun 01, 2010

Astanxanthin has a suppressive effect on retinal injury induced by elevated intraocular pressure.Oct 01, 2010

Astanxanthin improves artery thickness and vascular elastin in hypertension.Apr 01, 2006

Astaxanthin administration ameliorated oxidative stress caused by excess fructose.Feb 24, 2021

Astaxanthin alleviated acute lung injury by inhibiting oxidative/nitrative stress and the inflammatory response in mice.Sep 10, 2017

Astaxanthin alleviated aflatoxin B1-induced liver damage.Jul 02, 2019

Astaxanthin alleviates gestational diabetes mellitus in mice through suppression of oxidative stress.Apr 10, 2020

Astaxanthin alleviates ochratoxin A-induced cecum injury and inflammation.Dec 31, 2020

Astaxanthin alleviates pathological brain aging through the upregulation of hippocampal synaptic proteins.May 31, 2021

Astaxanthin

View the Evidence:
456 Abstracts with Astaxanthin Research