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Superoxide Dismutase Up-regulation
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234 Substances Researched for Superoxide Dismutase Up-regulation
Name
AC
CK
Focus
Curcumin
16
36
Astaxanthin
10
33
Chokeberry
5
33
Vitamin E
6
29
Milk Thistle
6
27
Nigella sativa (aka Black Seed)
10
27
Polyphenols
5
24
Alpha-Lipoic Acid
3
22
Green Tea
7
21
Curcuminoids
2
20
Cynanchum Auriculatum
1
20
Arginine
6
19
Turmeric
6
19
Ginsenosides
10
18
Bacopa
5
17
Resveratrol
10
16
Spirulina
4
16
Thymoquinone
8
16
Ashwagandha
4
15
Protandim
4
15
Anthocyanins
4
14
Zinc
3
14
Moringa oleifera
3
13
Camel Milk
2
12
Ginseng (Korean)
2
12
Nettle
2
12
Pine Needle
2
12
Silymarin
2
12
Verbascoside
6
11
Vitamin C
6
11
Amaranth
1
10
Bael
5
10
Carnosine
1
10
Chamomile
1
10
Cranberry
1
10
DHA (Docosahexaenoic Acid)
1
10
Fruit: All
1
10
Honey
1
10
Melatonin
6
10
Oranges
1
10
Puerarin
6
10
Royal Jelly
1
10
Vegetables: All
1
10
Ginkgo biloba
5
9
Quercetin
5
9
Sea buckthorn
5
9
Diosmin
4
8
Tanshinone IIA
4
8
Dandelion
4
7
Rose
4
7
Stilbenes
5
7
Adlay
3
6
Diosgenin
3
6
Fucoidan
4
6
Ginger
3
6
Grape Seed Extract
3
6
Hesperidin
3
6
Hydrogen Water
3
6
Lycopene
3
6
Medicinal Mushrooms
3
6
Myricetin
3
6
Selenium
3
6
Asiatic Acid
3
5
Black Raspberry
3
5
Chrysanthemum Indicum
3
5
Fermented Foods and Beverages
3
5
Papaya: Fermented
1
5
Rosemaric Acid
3
5
Sulforaphane
1
5
Apigenin
2
4
Artichoke
2
4
Boron
2
4
Cannabinoids
2
4
Carnosol
2
4
Carrot
2
4
Chrysin
2
4
Coconut Oil
2
4
Delta-tetrahydrocannabinol (THC)
2
4
Ellagic Acid
2
4
Garlic
2
4
Gastrodin
2
4
Gotu Kola
2
4
Lignans
2
4
Luteolin
2
4
Lychee
2
4
MSM (Methylsulfonylmethane)
2
4
Naringenin
2
4
Oleuropein
3
4
Panax Notoginseng
2
4
Prickly Pear Cactus
2
4
Prunella vulgaris
2
4
Pueraria mirifica
2
4
Reishi Mushroom
2
4
Rutin
2
4
Sesamin
2
4
Strawberry
2
4
Sweet Potato: Purple
2
4
Syrian rue
2
4
Tetrahydrocurcumin
2
4
Wheat Grass
2
4
Apple Pectin
2
3
Astragaloside
2
3
Barley
2
3
Blueberry
2
3
Chaga Mushroom (Inonotus obliquus)
2
3
Ferulic acid
2
3
Ginseng
2
3
Kefir
2
3
Litchi
2
3
Lotus
2
3
NAC (N-acetyl-L-cysteine)
2
3
Passion Flower
2
3
Phloretin
2
3
Sesamol
2
3
Achiote
1
2
Allicin
1
2
Aloe Vera
1
2
Alpha Ketoglutarate
1
2
Apple Polyphenols
1
2
Bai Zhu
1
2
Banana
1
2
Banana Leaf
1
2
Banana Stem
1
2
Beta-Caryophyllene
1
2
Buckwheat
1
2
Cabbage
1
2
Cannabidiol
1
2
Cannabigerol
1
2
Cannabis
1
2
Caprylic Acid
1
2
Carotenoids
1
2
Catechin
1
2
Chinese Medicine: Modified Simiao Decoction
1
2
Chlorella (Algae)
1
2
Cistanche deserticola
1
2
Citrus Peel
1
2
Citrus naringin
1
2
Coenzyme Q10
1
2
Cryptoxanthin
1
2
Curcuma Purpurascens
1
2
Cysteine (see N-Acetylcysteine)
1
2
D-Limonene
1
2
EPA (Eicosapentaenoic Acid)
1
2
Elderberry
1
2
False Black Pepper
1
2
Fenugreek
1
2
Flavonoids
1
2
Flaxseed
1
2
Fo ti
1
2
Galactooligosaccharides
1
2
Genistein
1
2
Geraniol
1
2
Glutamine
1
2
Grape
1
2
Gynostemma
1
2
Hawthorn
1
2
Hemp Seed
1
2
Hops
1
2
Huperzine
1
2
Indole-3-Carbinol
1
2
Jujube
1
2
Lactobacillus rhamnosus
1
2
Lemon Verbena
1
2
Lignan-converting bacteria
1
2
Lingonberry
1
2
Long Pepper
1
2
Loquat
1
2
Lutein
1
2
Maca
1
2
Magnolol
1
2
Mangosteen
1
2
Mastic gum
1
2
Modified Citrus Pectin
1
2
Mucuna pruriens (aka Velvet Beans)
1
2
Mushrooms: All
1
2
Muskmelon
1
2
Nordihydroguaiaretic acid (NDGA)
1
2
Okra
1
2
Olive
1
2
Olive leaf extract
1
2
Onion
1
2
Orange
1
2
Palmitoylethanolamide
1
2
Parsley
1
2
Passion fruit
1
2
Pelargonium sidoides
1
2
Persimmon
1
2
Plantago asiatica
1
2
Pomegranate
1
2
Prebiotics
1
2
Probiotics
1
2
Procyanidin B2
1
2
Propolis: Bee
1
2
Pterostilbene
1
2
Pumpkin
1
2
Pumpkin Seeds
1
2
Punicalagin
1
2
Purple Carrots
1
2
Pycnogenol (Pine Bark)
1
2
Rosemary
1
2
Rosmarinic acid
1
2
S-Adenosylmethionine (SAMe)
1
2
Saffron
1
2
Sage
1
2
Scolopendra subspinipes mutilans
1
2
Secoisolariciresinol diglucoside (SDG)
1
2
Silibinin
1
2
Spinach
1
2
Thujae occidentalis
1
2
Valerian
1
2
Virgin Coconut Oil
1
2
Vitamin D
1
2
Yellow Tea
1
2
Zerumbone
1
2
beta-Carotene
1
2
Antrodia cinnamomea
1
1
Asparagus
1
1
Astragalus
1
1
Blackberry
1
1
Burdock
1
1
Carnosic Acid
1
1
Cordyceps Militaris
1
1
Crocin
1
1
Gingerol
1
1
Graviola
1
1
Hibiscus sabdariffa
1
1
Ligustrazine
1
1
Nattokinase
1
1
Purslane
1
1
Raspberry
1
1
Rice: Black
1
1
Tangeretin
1
1
Urolithin A
1
1
Xanthohumol
1
1
Research Articles
415
Cumulative Knowledge Score
671
Overall Research Rating
EXCELLENT
View the Evidence:
549 Abstracts with Superoxide Dismutase Up-regulation Research
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[+]
Cynanchum auriculatum in combination with vitamin E exhibits anti-aging properties.
Dec 01, 2007
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(23):2511-4. PMID:
18330246
Article Published Date
: Dec 01, 2007
Study Type
: Meta Analysis
Additional Links
Substances
:
Cynanchum Auriculatum
,
Vitamin E
Diseases
:
Aging
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Telomerase Upregulation
[+]
This meta-analysis suggests that Nigella sativa supplementation in humans may benefit as an antioxidant.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ScientificWorldJournal. 2020 ;2020:2390706. Epub 2020 May 6. PMID:
32454800
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
A hydro alcoholic extract of nettle increased the levels of TAC and SOD in patients with type 2 diabetes.
Jan 14, 2012
Click here to read the entire abstract
Pubmed Data
: Pak J Biol Sci. 2012 Jan 15 ;15(2):98-102. PMID:
22545363
Article Published Date
: Jan 14, 2012
Study Type
: Human Study
Additional Links
Substances
:
Nettle
Diseases
:
Diabetes Mellitus: Type 2
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
A multi-herbal product called Protandim has significant antioxidant properties in human subjects.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Arzneimittelforschung. 2006;56(6):387-93. PMID:
16413416
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Ashwagandha
,
Bacopa
,
Green Tea
,
Milk Thistle
,
Protandim
,
Turmeric
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Alpha lipoic acid supplementation improved antioxidant enzyme activities in hemodialysis patients.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2019 Sep ;89(3-4):161-167. Epub 2019 Apr 16. PMID:
30987551
Article Published Date
: Aug 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Hemodialysis
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Alpha-lipoic acid treatment improves vision-related quality of life in patients with dry age-related macular degeneration.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Tohoku J Exp Med. 2016 ;240(3):209-214. PMID:
27840374
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Macular Degeneration
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
Additional Keywords
:
Alpha-Lipoic Acid
,
Macular Degeneration
,
Superoxide Dismutase Up-regulation
[+]
An acute dose of cranberry beverages improved biomarkers of antioxidant status and inhibition of bacterial adhesion in urine.
Apr 30, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2014 May ;34(5):420-7. Epub 2014 Apr 5. PMID:
24916555
Article Published Date
: Apr 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Cranberry
,
Polyphenols
Diseases
:
Escherichia coli Infections
,
Oxidative Stress
Pharmacological Actions
:
Anti-Bacterial Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Antioxidant effect of standardized extract of propolis.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2020 ;2020:7538232. Epub 2020 Oct 16. PMID:
33123209
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Astaxanthin prevents in vitro auto-oxidative injury in human lymphocytes.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Biol Toxicol. 2010 Oct;26(5):457-67. Epub 2010 Mar 14. PMID:
20229275
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Immune Disorders: Low Immune Function
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Apoptotic
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Astaxanthin protects smokers against oxidative stress.
Sep 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2011 Sep 1. Epub 2011 Sep 1. PMID:
21883001
Article Published Date
: Sep 01, 2011
Study Type
: Human Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Lipid Peroxidation
,
Oxidative Stress
,
Smoking
Pharmacological Actions
:
Antioxidants
,
Isoprostane Down-Regulation
,
Malonaldehyde (MDA) Down-Regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Tobacco: Smoking
Adverse Pharmacological Actions
:
Cardiotoxic
,
Oxidant
[+]
Camel milk could play an important role in improvement of autistic behaviours.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2013 ;2013:602834. Epub 2013 Aug 29. PMID:
24069051
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Camel Milk
Diseases
:
Autism
,
Autism Spectrum Disorders
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Chokeberry extract may be of benefit to patients with MS. This seems to result from the influence of anthocyanins and possibly other flavonoids on blood pressure, serum level of ET-1, lipids, and oxidative status.
Dec 31, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci Monit. 2010 Jan ;16(1):CR28-34. PMID:
20037491
Article Published Date
: Dec 31, 2009
Study Type
: Human Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Hypertension
,
Lipid Peroxidation
,
Metabolic Syndrome X
,
Oxidative Stress
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Coenzyme Q10 supplementation improved semen parameters and antioxidant status in men with idiopathic oligoasthenoteratospermia.
Aug 13, 2019
Click here to read the entire abstract
Pubmed Data
: Clin Exp Reprod Med. 2019 Aug 14. Epub 2019 Aug 14. PMID:
31408928
Article Published Date
: Aug 13, 2019
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Infertility: Male
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Consumption of either NPJ or HPJ protected against DNA damage and lipid peroxidation, modified several antioxidant enzymes, and reduced body weight.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2015 Aug ;145(8):1808-16. Epub 2015 Jul 1. PMID:
26136593
Article Published Date
: Jul 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Oranges
,
Polyphenols
Diseases
:
Lipid Peroxidation
,
Obesity
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Anti-Obesity Agents
,
Orange Juice
[+]
Consumption of encapsulated juice powder suppressed DNA damage in peripheral blood lymphocytes.
Mar 31, 2012
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2012 Apr ;56(4):666-70. Epub 2012 Mar 1. PMID:
22383296
Article Published Date
: Mar 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Fruit: All
,
Vegetables: All
Diseases
:
DNA damage
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cytoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Cuminum cyminum supplementation can improve some antioxidative indices, while decreasing malondialdehyde in patients with metabolic syndrome.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Apr ;33(4):1182-1190. Epub 2019 Feb 14. PMID:
30762267
Article Published Date
: Mar 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Cumin
Diseases
:
C-Reactive Protein
,
Inflammation
,
Metabolic Syndrome X
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Curcumin seems to be an efficient reducer of oxidative stress related complications in patients with PCOS.
Jan 07, 2020
Click here to read the entire abstract
Pubmed Data
: Diabetes Metab Syndr. 2020 Jan 8 ;14(2):77-82. Epub 2020 Jan 8. PMID:
31991296
Article Published Date
: Jan 07, 2020
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Polycystic Ovary Syndrome
Pharmacological Actions
:
Antioxidants
,
SIRT1 Activator
,
Superoxide Dismutase Up-regulation
[+]
Curcumin supplementation can attenuate exercise-induced oxidative stress by increasing blood antioxidant capacity.
May 31, 2014
Click here to read the entire abstract
Pubmed Data
: Int J Sports Med. 2014 Jun ;35(6):469-75. Epub 2013 Oct 28. PMID:
24165958
Article Published Date
: May 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Docosahexaenoic acid supplementation promotes erythrocyte antioxidant defense and reduces protein nitrosative damage in male athletes.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Lipids. 2015 Feb ;50(2):131-48. Epub 2014 Dec 16. PMID:
25503390
Article Published Date
: Jan 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Honey reduce the probable aggravating effects of intensive cycling training on spermatogenesis and fertility capacity in road cyclists.
Apr 30, 2012
Click here to read the entire abstract
Pubmed Data
: J Androl. 2012 May-Jun;33(3):449-61. Epub 2011 Jun 2. PMID:
21636735
Article Published Date
: Apr 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Honey
Diseases
:
Exercise-Induced Hormone Fluctuations
,
Infertility: Male
,
Oxidative Stress
Therapeutic Actions
:
Exercise: Cycling
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Immune modulatory and anti-oxidative effect of selenium against pulmonary tuberculosis.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2019 Mar ;32(2 (Supplementary)):779-784. PMID:
31103972
Article Published Date
: Feb 28, 2019
Study Type
: Human Study
Additional Links
Substances
:
Selenium
Diseases
:
Tuberculosis
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Korean red ginseng supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.
Jul 16, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr J. 2012 Jul 17 ;11:47. Epub 2012 Jul 17. PMID:
22805313
Article Published Date
: Jul 16, 2012
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Cholesterol: Oxidation
,
DNA damage
,
Hypertension
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
LED therapy can be useful to reduce muscle damage, pain, and atrophy, as well as to increase muscle mass and recovery.
Apr 14, 2016
Click here to read the entire abstract
Pubmed Data
: Am J Phys Med Rehabil. 2016 Apr 15. Epub 2016 Apr 15. PMID:
27088469
Article Published Date
: Apr 14, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Muscle Fatigue
,
Muscle Soreness
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Moringa oleifera and Amaranth possess antioxidant properties and have therapeutic potential for the prevention of complications during postmenopause.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Food Sci Technol. 2014 Nov ;51(11):3464-9. Epub 2012 Oct 5. PMID:
26396347
Article Published Date
: Oct 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Amaranth
,
Moringa oleifera
Diseases
:
Oxidative Stress
,
Postmenopausal Complications
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Nigella sativa oil concurrent with a low-calorie diet decreased weight and increased SOD levels in obese women.
Jul 13, 2015
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2015 Jul 14. Epub 2015 Jul 14. PMID:
26179113
Article Published Date
: Jul 13, 2015
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Obesity
,
Oxidative Stress
Therapeutic Actions
:
Dietary Modification: Low Calorie Diet
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Oral administration of L-arginine in patients with angina or following myocardial infarction may be protective.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Oxid Med Cell Longev. 2009 Sep-Oct;2(4):231-7. PMID:
20716909
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
Arginine
Diseases
:
Heart Attack: Recovery
,
Myocardial Infarction
Pharmacological Actions
:
Cardioprotective
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
,
Xanthine oxidase inhibitor
[+]
Our results suggest that the Aronia extract supplementation in breast cancer patients has a beneficial effect on thiols concentration in plasma.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2013 Jan ;372(1-2):47-55. Epub 2012 Sep 5. PMID:
22949034
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Breast Cancer
,
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Drug: Doxorubicin
,
Plant Extracts
[+]
Pinus koraiensis needle extract was effective in improving the superoxide dismutase in the individuals with borderline dyslipidemia.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2016 ;2016:9594251. Epub 2016 Aug 16. PMID:
27610187
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Pine Needle
Diseases
:
Dyslipidemias
Pharmacological Actions
:
Anticholesteremic Agents
,
Antihypertensive Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Probiotic yogurt improves antioxidant status in type 2 diabetic patients.
Apr 30, 2012
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2012 May ;28(5):539-43. Epub 2011 Nov 29. PMID:
22129852
Article Published Date
: Apr 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
,
Yoghurt
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Propolis supplementation improves glycemic and antioxidant status in patients with type 2 diabetes.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2019 Apr ;43:283-288. Epub 2019 Mar 2. PMID:
30935545
Article Published Date
: Mar 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Bee Propolis
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Reduction of oxidative-nitrosative stress underlies anticataract effect of topically applied tocotrienol in streptozotocin-induced diabetic rats.
Jan 01, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(3):e0174542. Epub 2017 Mar 28. PMID:
28350848
Article Published Date
: Jan 01, 2017
Study Type
: Human Study
Additional Links
Substances
:
Tocotrienols
Diseases
:
Cataract
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Royal jelly supplementation may be beneficial in controlling diabetes outcomes.
Apr 30, 2014
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2014 May ;20(5):347-52. Epub 2014 Mar 7. PMID:
24610413
Article Published Date
: Apr 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Royal Jelly
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
Therapeutic Actions
:
Placebo Effect
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Short term intake of chamomile tea has beneficial effects on glycemic control and antioxidant status in patients with T2 DM.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrition. 2016 Jan ;32(1):66-72. Epub 2015 Aug 14. PMID:
26437613
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Chamomile
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Risk Reduction
[+]
Short-term supplementation with curcuminoids attenuates systemic oxidative stress in patients with osteoarthritis.
Feb 16, 2015
Click here to read the entire abstract
Pubmed Data
: J Diet Suppl. 2015 Feb 17. Epub 2015 Feb 17. PMID:
25688638
Article Published Date
: Feb 16, 2015
Study Type
: Human Study
Additional Links
Substances
:
Curcuminoids
Diseases
:
Osteoarthritis
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Silymarin has an efficacy to prevent liver injury from standard combined antituberculosis drugs without significant adverse effects.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15(1):334. Epub 2015 Sep 23. PMID:
26400476
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Silymarin
Diseases
:
Liver Damage: Drug-Induced
,
Tuberculosis
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Silymarin supplementation improves some antioxidant indices and decreased high-sensitivity C-reactive protein levels in T2DM patients.
Feb 14, 2015
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2015 Feb 15 ;22(2):290-6. Epub 2015 Jan 19. PMID:
25765835
Article Published Date
: Feb 14, 2015
Study Type
: Human Study
Additional Links
Substances
:
Milk Thistle
Diseases
:
C-Reactive Protein
,
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Six weeks consumption of green tea extract caused a marked increase in the blood antioxidant capacity and a moderate attenuation of the training-induced lipid peroxidation.
Mar 21, 2019
Click here to read the entire abstract
Pubmed Data
: J Int Soc Sports Nutr. 2019 Mar 21 ;16(1):13. Epub 2019 Mar 21. PMID:
30898134
Article Published Date
: Mar 21, 2019
Study Type
: Human Study
Additional Links
Substances
:
Tea
Diseases
:
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Spirulina intake for 30 and 60 days led to a significant reduced serum content of MDA, lipid hydroperoxide, and cholesterol, while increasing GSH and vitamin C level.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2015 ;2015:486120. Epub 2015 Jan 22. PMID:
25685791
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Spirulina
Diseases
:
Chronic Obstructive Pulmonary Disease
,
Oxidative Stress
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidant Effects
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Significant Treatment Outcome
[+]
Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate levels.
Jun 30, 2003
Click here to read the entire abstract
Pubmed Data
: Biol Psychol. 2003 Jul ;63(3):281-91. PMID:
12853172
Article Published Date
: Jun 30, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Yoga
,
Yogic Technique: Sudarshan kriya
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Supplementation with Curcuminoids caused a significant elevation in serum total antioxidant capacity in subjects with T2DM.
Dec 06, 2016
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2016 Dec 7. Epub 2016 Dec 7. PMID:
27928704
Article Published Date
: Dec 06, 2016
Study Type
: Human Study
Additional Links
Substances
:
Curcuminoids
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
,
Diabetic Complications
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Supplementation with green tea extract prevents exercise-induced oxidative stress.
Aug 01, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Nutr. 2015 Aug ;54(5):783-91. Epub 2014 Aug 14. PMID:
25120110
Article Published Date
: Aug 01, 2015
Study Type
: Human Study
Additional Links
Substances
:
Green Tea
,
Polyphenols
,
Tea
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
The use of a food supplement containing α-lipoic acid seems to bring an improvement in glycemic control and in lipid profile.
Oct 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2016 Oct 28 ;17(11). Epub 2016 Oct 28. PMID:
27801825
Article Published Date
: Oct 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
,
Carnosine
,
Zinc
Diseases
:
C-Reactive Protein
,
Diabetes Mellitus: Type 2
,
Inflammation
,
Insulin Resistance
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hypolipidemic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
These findings indicate that an increased intake of anthocyanins limits the exercise induced oxidative damage to red blood cells
Jan 31, 2005
Click here to read the entire abstract
Pubmed Data
: Int J Sport Nutr Exerc Metab. 2005 Feb ;15(1):48-58. PMID:
15902989
Article Published Date
: Jan 31, 2005
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Chokeberry
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Exercise Induced Oxidative Damage
[+]
Treatment with NAC may help to reduce oxidative and inflammatory damage in pneumonia patients.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Medicine (Baltimore). 2018 Nov ;97(45):e13087. PMID:
30407312
Article Published Date
: Oct 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Inflammation
,
Oxidative Stress
,
Pneumonia
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Whole body cryotherapy appears to reduce oxidative stress in multiple sclerosis patients.
Sep 01, 2011
Click here to read the entire abstract
Pubmed Data
: Pol Merkur Lekarski. 2011 Sep ;31(183):150-3. PMID:
21991843
Article Published Date
: Sep 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Multiple Sclerosis
,
Oxidative Stress
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Yoga can be practiced as adjuvant therapy with standard inhalation therapy for better outcome of asthma.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Yoga. 2014 Jan ;7(1):17-21. PMID:
25035603
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Diseases
:
Asthma
Therapeutic Actions
:
Integrative Medicine
,
Yoga
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Fermented papaya may have a protective effect on platelets from patients with patients with type 2 diabetes.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2015 Feb ;25(2):224-9. Epub 2014 Nov 1. PMID:
25511784
Article Published Date
: Jan 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Papaya: Fermented
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Genetic polymorphisms affect superoxide dismutase activity may potentiate the negative effects of magnetic fields.
Feb 01, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2017 Feb ;24(5):5078-5088. Epub 2016 Dec 21. PMID:
28004364
Article Published Date
: Feb 01, 2017
Study Type
: Human In Vitro
Additional Links
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Apoptotic
,
Superoxide Dismutase Up-regulation
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
[+]
Sulforaphane protected the injury of vascular endothelial cell by LPC by enhancing anti-oxidative capabilities mediated by Nrf-2 translocation.
May 25, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 May 26. Epub 2015 May 26. PMID:
26008201
Article Published Date
: May 25, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Endothelial Damage
,
Endothelial Dysfunction
Pharmacological Actions
:
Antioxidants
,
Phase II Detoxification Enzyme Inducer
,
Superoxide Dismutase Up-regulation
[+]
Purple grape juices prevent pentylenetetrazol-induced oxidative damage in the liver and serum of Wistar rats.
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2013 Feb ;33(2):120-5. Epub 2013 Jan 17. PMID:
23399662
Article Published Date
: Jan 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Grape
,
Polyphenols
Diseases
:
Lipid Peroxidation
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
"Galactooligosaccharide improves the animal survival and alleviates motor neuron death in SOD1G93A mouse model of amyotrophic lateral sclerosis."
Aug 28, 2013
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2013 Aug 29 ;246:281-90. Epub 2013 May 11. PMID:
23673277
Article Published Date
: Aug 28, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Galactooligosaccharides
,
Prebiotics
Diseases
:
Amyotrophic Lateral Sclerosis
Pharmacological Actions
:
Apoptotic
,
Superoxide Dismutase Up-regulation
[+]
"Suppression by fucoidan of liver fibrogenesis via the TGF-β/Smad pathway in protecting against oxidative stress."
Dec 31, 2010
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2011 ;75(5):833-40. Epub 2011 May 20. PMID:
21597183
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Liver Cirrhosis
,
Liver Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
2,3,5,4'-Tetrahydroxystilbene-2-O- β -D-glucoside increases life span and stress resistance of Caenorhabditis elegans.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2015 ;2015:124357. Epub 2015 May 5. PMID:
26075030
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Aging
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
20(S)-ginsenoside Rg(3) showed the significant protective effects on cyclophosphamide-induced cell DNA damage and apoptosis.
Jan 31, 2008
Click here to read the entire abstract
Pubmed Data
: Arch Toxicol. 2008 Feb ;82(2):117-23. Epub 2007 Jun 28. PMID:
17598087
Article Published Date
: Jan 31, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
3% spirulina supplementation in high-energy diet ameliorated lipid metabolic disorder and oxidative stress.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Meat Sci. 2020 Jun ;164:108094. Epub 2020 Feb 25. PMID:
32146297
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Spirulina
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
[+]
50 GHz microwave radiation exposure at a specific absorption rate of 0.014 W/kg induces oxidative and genotoxic stress in rats.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Indian J Exp Biol. 2010 Jun ;48(6):586-92. PMID:
20882761
Article Published Date
: Jun 01, 2010
Study Type
: Animal Study
Additional Links
Diseases
:
DNA damage
,
Oxidative Stress
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
Anti Therapeutic Actions
:
5G Millimeter Wave Radiation
,
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Genotoxic
,
Oxidant
[+]
A blueberry extract showed an important cardioprotective effect by the improvements in the serum lipid profile and antioxidant system.
Jul 13, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2015 Jul 14:1-10. Epub 2015 Jul 14. PMID:
26171628
Article Published Date
: Jul 13, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Hypercholesterolemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-atherogenic
,
Antioxidants
,
Cardioprotective
,
Superoxide Dismutase Up-regulation
[+]
A Chinese formula Modified Simiao Decoction regulates renal urate transporters and enhancing antioxidant enzymes activities to improve renal dysfunction in hyperuricemic mice.
Jun 25, 2012
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2012 Jun 26 ;142(1):248-52. Epub 2012 May 8. PMID:
22575704
Article Published Date
: Jun 25, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Chinese Medicine: Modified Simiao Decoction
Diseases
:
Hyperuricemia
,
Uric Acid Nephropathy
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Renoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
[+]
A comparative study on immune-stimulatory and antioxidant activities of various types of ginseng extracts.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2018 Oct ;42(4):577-584. Epub 2018 Jul 17. PMID:
30344431
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
A hemp seed meal protein hydrolysate contained antioxidant peptides that reduced the rate of lipid peroxidation in spontaneously hypertensive rats.
Nov 30, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2014 Dec ;6(12):5652-66. PMID:
25493943
Article Published Date
: Nov 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cannabis
,
Hemp Seed
Diseases
:
Hypertension
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
A methanolic extract of Chaga mushroom led to a significant enhancement of cognitive abilities in the observed mice.
May 31, 2011
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2011 Jun ;2(6):320-7. Epub 2011 Jun 6. PMID:
21779570
Article Published Date
: May 31, 2011
Study Type
: Animal Study
Additional Links
Diseases
:
Amnesia: Drug-Induced
,
Cognitive Decline/Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
A mixture of curcumin, hesperidin and rutin ameliorates hepatic oxidative stress caused by STZ-induced hyperglycemia.
Aug 11, 2015
Click here to read the entire abstract
Pubmed Data
: Curr Neurovasc Res. 2015 Aug 12. Epub 2015 Aug 12. PMID:
26265154
Article Published Date
: Aug 11, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Hesperidin
,
Rutin
Diseases
:
Diabetes Mellitus: Type 2
,
Hyperglycemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Hypoglycemic Agents
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
[+]
A multi-herbal product called Protandim exhibits chemopreventive properties in a mouse model of skin cancer.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2010;5(7):e11902. Epub 2010 Jul 30. PMID:
20689586
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ashwagandha
,
Bacopa
,
Green Tea
,
Milk Thistle
,
Protandim
,
Turmeric
Diseases
:
Skin Cancer
Pharmacological Actions
:
Apoptotic
,
Chemopreventive
,
Superoxide Dismutase Up-regulation
,
Tumor Suppressor Protein p53 Upregulation
[+]
A multi-herbal product called Protandim has chemopreventive properties against skin cancer.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2009;4(4):e5284. Epub 2009 Apr 22. PMID:
19384424
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ashwagandha
,
Bacopa
,
Green Tea
,
Milk Thistle
,
Protandim
,
Turmeric
Diseases
:
Oxidative Stress
,
Skin Cancer
Pharmacological Actions
:
Antioxidants
,
NF-kappa-B-inducing kinase (NIK) modulator
,
Superoxide Dismutase Up-regulation
,
Tumor Suppressor Protein p53 Upregulation
,
Vascular Cell Adhesion Molecule-1 Inhibitor
[+]
A phenolic rich extract of wild cabbage has the potential to form a multi-component drug to target diabetes and its related complications.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Springerplus. 2015 ;4:212. Epub 2015 May 3. PMID:
26020019
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Cabbage
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Hypoglycemic Agents
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
A thymoquinone-rich fraction extracted from Nigella sativa effectively improved the plasma and liver antioxidant capacity.
Feb 28, 2010
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2010 Mar 1 ;48(5):664-72. Epub 2009 Dec 11. PMID:
20005291
Article Published Date
: Feb 28, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Hypercholesterolemia
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Gene Expression Regulation
[+]
A. catechu seed extract is a promising agent for protecting liver from acetaminophen induced hepatotoxicity.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2018 Dec ;108:838-844. Epub 2018 Sep 24. PMID:
30372895
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Acacia catechu
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Acteoside can significantly alleviate the acquired learning disability in mice induced by scopolamine.
Sep 30, 2012
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2012 Oct ;37(19):2956-9. PMID:
23270241
Article Published Date
: Sep 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Learning disorders
,
Memory Disorders
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Acteoside has a protective and therapeutic effect on LPS-induced immunological liver injury in mice.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2009 Nov ;75(14):1463-9. Epub 2009 Jun 22. PMID:
19548187
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Acteoside has beneficial effects on lipopolysaccharide-induced inflammation in acute lung injury.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2015 Jun 1 ;285(2):128-35. Epub 2015 Apr 19. PMID:
25902336
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Aegle marmelos fruit extract attenuates Helicobacter pylori Lipopolysaccharide induced oxidative stress.
Oct 18, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 Oct 19 ;15:375. Epub 2015 Oct 19. PMID:
26482072
Article Published Date
: Oct 18, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Gastric Ulcer
,
Helicobacter Pylori Infection
,
Lipid Peroxidation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Aegle marmelos fruit extract exhibits protective effects on the pancreas.
Dec 31, 2004
Click here to read the entire abstract
Pubmed Data
: J Herb Pharmacother. 2005 ;5(3):87-96. PMID:
16520300
Article Published Date
: Dec 31, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Pancreato Protective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Algal lycopene showed very significant antioxidant and anti-inflammatory effect in high-cholesterol fed rats.
Jan 31, 2014
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2014 Feb ;22(1):45-54. Epub 2013 Jul 26. PMID:
23887896
Article Published Date
: Jan 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
,
Lycopene
Diseases
:
C-Reactive Protein
,
Hypercholesterolemia
,
Hyperlipidemia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticholesteremic Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Allicin has powerful protective effects against ischemia/hypoxia-induced cell apoptosis.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:3207973. Epub 2018 Apr 16. PMID:
29849702
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Heme oxygenase-1 up-regulation
,
Superoxide Dismutase Up-regulation
[+]
Aloe vera or resveratrol supplementation in larval diet delays adult aging in the fruit fly, Drosophila melanogaster.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Gerontol A Biol Sci Med Sci. 2011 Sep ;66(9):965-71. Epub 2011 Jun 30. PMID:
21719611
Article Published Date
: Aug 31, 2011
Study Type
: Insect Study
Additional Links
Substances
:
Aloe Vera
,
Resveratrol
,
Stilbenes
Diseases
:
Aging
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
[+]
Alpha mangostin attenuated hepatic steatosis in high fat-diet fed rats potentially through enhanced cellular antioxidant capacity.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2016 ;13:88. Epub 2016 Dec 1. PMID:
27980597
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Mangosteen
Diseases
:
High Fat Diet
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Catalase Up-Regulation
,
Glutathione Upregulation
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Alpha-lipoic acid markedly attenuated Con A-induced hepatitis by modulating cytokine secretion and reducing reactive oxygen species generation.
Mar 24, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Mar 25 ;35:53-60. Epub 2016 Mar 25. PMID:
27018751
Article Published Date
: Mar 24, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Hepatitis: Lectin-Induced (concanavalin)
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Concanavalin A
[+]
Aluminum increases free iron in the brain which may contribute to neurodegeneration.
Nov 01, 2001
Click here to read the entire abstract
Pubmed Data
: J Inorg Biochem. 2001 Nov ;87(1-2):9-14. PMID:
11709207
Article Published Date
: Nov 01, 2001
Study Type
: Animal Study
Additional Links
Diseases
:
Neurodegenerative Diseases
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
Anti Therapeutic Actions
:
Vaccination: All
Problem Substances
:
Aluminum
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Ameliorative effect of Aegle marmelos leaf extract on early stage alloxan-induced diabetic cardiomyopathy in rats.
Oct 31, 2011
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2011 Nov ;49(11):1137-43. PMID:
22014262
Article Published Date
: Oct 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Cardiomyopathy
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Ameliorative effect of diosmin against streptozotocin-nicotinamide generated oxidative stress induced by diabetes.
Jan 04, 2012
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2012 Jan 5 ;195(1):43-51. Epub 2011 Oct 28. PMID:
22056647
Article Published Date
: Jan 04, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Superoxide Dismutase Up-regulation
[+]
An ethanol extract of Glycyrrhiza glabra poses anti-convulsant potential and ameliorates ROS induced neuronal damage in PTZ-induced seizure.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Indian J Pharmacol. 2013 Jan-Feb;45(1):40-3. PMID:
23543836
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Oxidative Stress
,
Seizures
Pharmacological Actions
:
Anticonvulsants
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
An ethyl acetate extract of persimmon leaves has a potent protective effect on cognitive deficits induced by Aβ in rats.
Jun 14, 2016
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2016 Jun 15 ;23(7):694-704. Epub 2016 Apr 11. PMID:
27235708
Article Published Date
: Jun 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Persimmon
Pharmacological Actions
:
Anti-Apoptotic
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
An extract from roots of Pelargonium sidoides could be beneficial in respiratory tract infections.
Apr 14, 2015
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2015 Apr 15 ;22(4):504-9. Epub 2015 Mar 20. PMID:
25925973
Article Published Date
: Apr 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Pelargonium sidoides
Diseases
:
Cough
,
Respiratory Tract Infections
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Antitussive Agents
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
An extract of curcuma purpurascens was found to be gastroprotective against ethanol induced damage.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2014 ;14:378. Epub 2014 Oct 6. PMID:
25283308
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Curcuma Purpurascens
Diseases
:
Gastric Ulcer
,
Methanol Toxicity
Pharmacological Actions
:
Anti-Ulcer Agents
,
Gastroprotective
,
Heat Shock Protein Inducer
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Annatto extract and β-carotene enhances antioxidant status and regulate gene expression in neutrophils of diabetic rats.
Feb 29, 2012
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2012 Mar ;46(3):329-38. Epub 2012 Feb 6. PMID:
22239725
Article Published Date
: Feb 29, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Achiote
,
beta-Carotene
Diseases
:
Diabetes Mellitus: Type 2
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
MicroRNA modulator
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Gene Expression Regulation
,
Plant Extracts
[+]
Anti-fatigue effect of anwulignan via the NRF2 and PGC-1α signaling pathway in mice.
Dec 10, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Dec 11 ;10(12):7755-7766. PMID:
31696200
Article Published Date
: Dec 10, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Schisandra
Diseases
:
Fatigue: Excercise-Induced
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
Antifatigue properties of tanshinone IIA in mice subjected to the forced swimming test.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):2264-2269. PMID:
29171356
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Fatigue: Excercise-Induced
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Antihyperglycemic activity of bacosine.
Apr 30, 2011
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2011 May ;77(8):804-8. Epub 2010 Dec 10. PMID:
21154199
Article Published Date
: Apr 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Antioxidant and anti hyperglycemic role of wine grape powder in rats fed with a high fructose diet.
Sep 29, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Res. 2015 Sep 30 ;48:53. Epub 2015 Sep 30. PMID:
26420015
Article Published Date
: Sep 29, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Grape
Diseases
:
High Fructose Diet
,
Insulin Resistance
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
Problem Substances
:
Fructose
[+]
Antioxidant and anti-diabetic activities of polysaccharides from guava leaves.
Apr 04, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Apr 5 ;24(7). Epub 2019 Apr 5. PMID:
30959759
Article Published Date
: Apr 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Guava
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
,
Polysaccharides
[+]
Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2016 Jun ;37(6):1501-10. Epub 2016 Apr 20. PMID:
27121241
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
acetyl-11-keto-beta-boswellic acid
,
Safflower
Diseases
:
Hypoxia
,
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
Antioxidant mechanism of diallyl sulfide in inhibiting leucopenia in peripheral blood induced by benzene.
Oct 19, 2019
Click here to read the entire abstract
Pubmed Data
: Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2019 Oct 20 ;37(10):737-745. PMID:
31726503
Article Published Date
: Oct 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Diallyl sulfide
Diseases
:
Benzene Toxicity
,
Leucopenia
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Benzene
[+]
Antioxidants exhibited protective effects against D-galactose-induced oxidative damage in rats.
Mar 29, 2016
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2016 Mar 30. Epub 2016 Mar 30. PMID:
27025718
Article Published Date
: Mar 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Purple Carrots
,
Selenium
,
Vitamin E
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Natural Substance Synergy
[+]
Apigenin and naringenin can ameliorate glucose and lipid metabolism, as well as endothelial dysfunction in T2D rats
Jan 19, 2016
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2016 Jan 20. Epub 2016 Jan 20. PMID:
26801071
Article Published Date
: Jan 19, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Naringenin
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Apigenin has good hepatoprotective effects and potential as a promising therapeutic agent for acute liver failure in clinical application.
Jan 10, 2019
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2019 Jan 11 ;68:171-178. Epub 2019 Jan 11. PMID:
30641432
Article Published Date
: Jan 10, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
,
Chrysin
,
Luteolin
Diseases
:
Liver Failure: Acute
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
Arctigenin attenuates ischemia/reperfusion induced ventricular arrhythmias.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;49(2):728-742. Epub 2018 Aug 30. PMID:
30165360
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Lignans
Diseases
:
Myocardial Infarction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Aronia melanocarpa could be beneficial for non-alcoholic fatty liver disease.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(1):e0169685. Epub 2017 Jan 12. PMID:
28081181
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Artesunate affords protection against aspirin-induced gastric injury.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2018 Apr ;70(2):390-397. Epub 2017 Jun 15. PMID:
29397336
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Aspirin-Induced Toxicity
,
Gastric Ulcer
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Ulcer Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Natural Substances Versus Drugs
Problem Substances
:
Aspirin
[+]
Artichoke leaf extract may be used as a pharmaceutical phytomedicine in the treatment of liver diseases.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Springerplus. 2016 ;5:216. Epub 2016 Feb 29. PMID:
27026910
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Ascorbic acid contributes to the reduction of oxidative stress and inflammatory response in DSS-induced colitis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015 ;8(11):20245-53. Epub 2015 Nov 15. PMID:
26884937
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Gastrointestinal Inflammation
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Ascorbic acid inhibits cadmium-induced disruption of the blood-testis barrier.
May 21, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2018 May 22. Epub 2018 May 22. PMID:
29790047
Article Published Date
: May 21, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Testicular Injury: Cadmium-Induced
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Cadmium
[+]
Asiatic acid attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells.
Apr 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Pharmacol Sin. 2012 May ;33(5):578-87. Epub 2012 Mar 26. PMID:
22447225
Article Published Date
: Apr 30, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Cognitive Decline/Dysfunction
,
Dementia
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Apoptotic
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
Asiatic acid has the potential to treat inflammatory disease such as COPD.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Oct ;39:208-217. Epub 2016 Aug 3. PMID:
27494684
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Chronic Obstructive Pulmonary Disease
,
Smoking
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
[+]
Astaxanthin attenuates acute cerebral infarction via Nrf-2/HO-1 pathway in rats.
Jan 17, 2021
Click here to read the entire abstract
Pubmed Data
: Curr Res Transl Med. 2021 Jan 18 ;69(2):103271. Epub 2021 Jan 18. PMID:
33476935
Article Published Date
: Jan 17, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Stroke
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astaxanthin attenuates environmental tobacco smoke-induced cognitive deficits.
Jan 02, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2019 Jan 3 ;17(1). Epub 2019 Jan 3. PMID:
30609815
Article Published Date
: Jan 02, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Cognitive Decline/Dysfunction
,
Tobacco Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Glutathione Upregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astaxanthin from H. pluvialis shows better bioavailability than beta-carotene and lutein and has significant antixoxidant properties.
Aug 11, 2010
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2010 Aug 11;58(15):8553-9. PMID:
20681642
Article Published Date
: Aug 11, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
,
Carotenoids
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Astaxanthin has radioprotective properties against cobalt-60 gamma radiation induced oxidative stress and DNA damage.
Sep 01, 2011
Click here to read the entire abstract
Pubmed Data
: Wei Sheng Yan Jiu. 2011 Sep ;40(5):551-4. PMID:
22043699
Article Published Date
: Sep 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
DNA damage
,
Radiation Induced Illness
,
Radiation Induced Illness: Bone Marrow
Pharmacological Actions
:
Genoprotective
,
Glutathione Peroxidase 1 (GPx1) Up-Regulation
,
Malonaldehyde (MDA) Down-Regulation
,
Radioprotective
,
Superoxide Dismutase Up-regulation
[+]
Astaxanthin may be benefit for prevention and treatment of preeclampsia disease.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Yao Xue Xue Bao. 2014 Oct ;49(10):1400-5. PMID:
25577869
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Pre-Eclampsia
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Nitric Oxide Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Astaxanthin protects against cyclophosphamide-induced oxidative stress and DNA damage.
Aug 14, 2009
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2009 Aug 14;180(3):398-406. Epub 2009 Apr 2. PMID:
19539803
Article Published Date
: Aug 14, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
DNA damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Astragaloside IV protective effect of against paraquat-induced lung injury.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2016 Feb ;39(1):483-492. PMID:
26452991
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Paraquat
[+]
Astragaloside IV protects rat gastric mucosa against aspirin-induced damage.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Dec ;41:47-55. Epub 2016 Nov 2. PMID:
27816726
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Aspirin-Induced Toxicity
,
Gastric Ulcer
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cyclooxygenase 1 Inhibitor
,
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Aspirin
[+]
Atractylodes macrocephala polysaccharide has protective effects on liver ischemia-reperfusion injury.
Dec 31, 2010
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2011 ;39(3):489-502. PMID:
21598417
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bai Zhu
Diseases
:
Lipid Peroxidation
,
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Antioxidants
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Attenuation of hyperglycemia-mediated oxidative stress by indole-3-carbinol and its metabolite 3, 3'- diindolylmethane.
May 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Physiol Biochem. 2014 Jun ;70(2):525-34. Epub 2014 Apr 9. PMID:
24715233
Article Published Date
: May 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Indole-3-Carbinol
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
,
Hyperglycemia
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Bacopa monniera may have therapeutic value for the treatment of cognitive impairment.
Jan 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Metab Brain Dis. 2015 Feb ;30(1):115-27. Epub 2014 Jul 19. PMID:
25037167
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Cognitive Decline/Dysfunction
,
Lipid Peroxidation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Beneficial effects of ascorbic acid to treat lung fibrosis induced by paraquat.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2018 ;13(11):e0205535. Epub 2018 Nov 5. PMID:
30395570
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Fibrosis
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Paraquat
[+]
Beta-caryophyllene can be used to treat dyslipidemic diseases because it exerts a similar effect as simvastatin.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Naunyn Schmiedebergs Arch Pharmacol. 2017 Feb ;390(2):215-223. Epub 2016 Dec 2. PMID:
27913825
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Beta-Caryophyllene
Diseases
:
Dyslipidemias
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Natural Substances Versus Drugs
Problem Substances
:
Simvastatin
,
Statin Drugs
[+]
Biochanin A ameliorates arsenic-induced hepato- and hematotoxicity in rats.
Jan 08, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2016 Jan 9 ;21(1):69. Epub 2016 Jan 9. PMID:
26760991
Article Published Date
: Jan 08, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Arsenic Poisoning
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Glutathione Upregulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Arsenic
[+]
Biochanin A has gastroprotective effects in ethanol-induced gastric mucosal ulceration.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(3):e0121529. Epub 2015 Mar 26. PMID:
25811625
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Alcohol Toxicity
,
Gastric Ulcer
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Blueberry anthocyanin extract significantly delayed the progression of diabetic cataracts.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Curr Eye Res. 2020 Jun 1. Epub 2020 Jun 1. PMID:
32478572
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blueberry
Diseases
:
Diabetes: Cataract
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Boron supplementation increased the hepatic mRNA expression levels of both SOD isoenzymes, thereby improving the immune and antioxidant status.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: J Trace Elem Med Biol. 2016 Jul ;36:73-9. Epub 2016 Apr 25. PMID:
27259355
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Boron
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Both Nigella sativa and thymoquinone can partly protect gastric mucosa from acute alcohol-induced mucosal injury.
Nov 13, 2005
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2005 Nov 14 ;11(42):6662-6. PMID:
16425361
Article Published Date
: Nov 13, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Alcohol Toxicity
Pharmacological Actions
:
Gastroprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Both Nigella sativa oil and thymoquinone possess gastroprotective effect against gastric lesions.
Jan 31, 2003
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2003 Feb ;84(2-3):251-8. PMID:
12648823
Article Published Date
: Jan 31, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Ischemia
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Ulcer Agents
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Oils
[+]
Brazilian green propolis hydroalcoholic extract reduces colon damages caused by dextran sulfate sodium-induced colitis in mice.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2018 Oct ;26(5):1283-1292. Epub 2018 Apr 9. PMID:
29633104
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Brazillian
Diseases
:
Colitis
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Broccoli sprout extract containing sulforaphane attentuated alcohol-induced oxidative stress and endoplasmic reticulum stress through restoration of antioxidant enzyme function in mice.
Jun 06, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Jun 6 ;66(22):5574-5580. Epub 2018 May 23. PMID:
29730925
Article Published Date
: Jun 06, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli Sprouts
,
Sulforaphane
Diseases
:
Alcohol Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Nrf2 activation
,
Phase II Detoxification Enzyme Inducer
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
By promoting fertility and eliminating oxidative stress and inflammation, Punicalagin may be a useful nutrient for the treatment of infertility.
Jan 11, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian J Androl. 2016 Jan 12. Epub 2016 Jan 12. PMID:
26763544
Article Published Date
: Jan 11, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Infertility: Male
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Fertility Agents
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
C. aronia inhibits high fat diet-induced vascular inflammation.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2019 Dec ;57(1):38-48. PMID:
30702358
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Hawthorn
Diseases
:
Cholesterol: Oxidation
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Cannabichromene could be considered for clinical experimentation in inflammatory bowel disease patients.
Apr 30, 2013
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2013 May 1 ;85(9):1306-16. Epub 2013 Feb 12. PMID:
23415610
Article Published Date
: Apr 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Cannabigerol
,
Cannabinoids
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Nitric Oxide Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2012 ;7(11):e49191. Epub 2012 Nov 7. PMID:
23145119
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Caprylic Acid
Diseases
:
Amyotrophic Lateral Sclerosis
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
[+]
Carnosic acid attenuates acrylamide-induced retinal toxicity in zebrafish embryos.
Jan 09, 2018
Click here to read the entire abstract
Pubmed Data
: Exp Eye Res. 2018 10 ;175:103-114. Epub 2018 Jun 18. PMID:
29928899
Article Published Date
: Jan 09, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Acrylamide-induced toxicity
,
Eye Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Acrylamide
[+]
Carnosol pretreatment attenuates liver injury induced by intestinal ischemia reperfusion.
Jul 13, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2009 Jul 14 ;15(26):3240-5. PMID:
19598299
Article Published Date
: Jul 13, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Carnosol
Diseases
:
Intestinal Ischemia
Pharmacological Actions
:
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Catechin mitigates thyroxine-induced oxidative stress in the liver and testis of rats.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Med Case Reports. 2009;3:9295. Epub 2009 Nov 24. PMID:
20882757
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Catechin
Diseases
:
Drug-Induced Toxicity: L-Thyroxine
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Centella asiatica may be useful in preventing liver damage.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Nov ;14(5):4521-4528. Epub 2016 Oct 5. PMID:
27748812
Article Published Date
: Oct 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-10 downregulation
,
Interleukin-12 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Chaga mushroom possesses significant antihyperglycaemic, antilipidperoxidative and antioxidant effects in alloxan-induced diabetic mice.
Mar 31, 2010
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2010 Apr ;24(6):542-53. PMID:
20397104
Article Published Date
: Mar 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Chaga Mushroom (Inonotus obliquus)
Diseases
:
Diabetes Mellitus: Type 2
,
Hyperglycemia
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Changes in lipid metabolism, antioxidant status and intestinal microflora can be greatly modulated by Bacillus-fermented adlay.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2011 Sep ;91(12):2271-6. Epub 2011 May 26. PMID:
21618546
Article Published Date
: Aug 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Adlay
,
Fermented Foods and Beverages
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Antioxidants
,
Gastrointestinal Agents
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
[+]
Chemoprevention by Triticum Aestivum of mouse skin carcinogenesis induced by DMBA and croton oil.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Cancer Prev. 2011 ;12(1):143-8. PMID:
21517247
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Wheat Grass
Diseases
:
Lipid Peroxidation
,
Skin Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
Problem Substances
:
Croton oil
[+]
Chrysanthemum indicum demonstrates a beneficial role in preventing inflammation and the effects of oxidative stress.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2017 ;2017:8206281. Epub 2017 Feb 2. PMID:
28261616
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Spondylitis: Ankylosing
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Cistanche deserticola exhibits anti-aging properties in mice.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Zhong Yao Cai. 2008 Sep;31(9):1385-8. PMID:
19180965
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Cistanche deserticola
Diseases
:
Aging
,
Aging: Brain
,
Learning disorders
,
Memory Loss
,
Oxidative Stress
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Co-administration of melatonin mitigated chemotherapy induced testicular dysfunction.
Jun 14, 2015
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2015 Jun 15:1-10. Epub 2015 Jun 15. PMID:
26072956
Article Published Date
: Jun 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Chemotherapy-Induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
Co-administration of resveratrol and vitamin D protects the heart against aging-induced damage.
Nov 26, 2018
Click here to read the entire abstract
Pubmed Data
: Aging Clin Exp Res. 2018 Nov 27. Epub 2018 Nov 27. PMID:
30484255
Article Published Date
: Nov 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
,
Vitamin D
Diseases
:
Aging: Heart
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Coenzyme Q10 has a coloprotective effect against experimentally induced ulcerative colitis.
Jan 02, 2017
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2017 Jan 3. Epub 2017 Jan 3. PMID:
28050757
Article Published Date
: Jan 02, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Glutathione Upregulation
,
Heme oxygenase-1 up-regulation
,
Malondialdehyde Down-regulation
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
Combined administration of selenium enriched green tea polysaccharides and Huo-ji polysaccharides synergistically improve immune function and decrease the oxidative stress.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2015 Jul 1. Epub 2015 Jul 1. PMID:
26130565
Article Published Date
: Jun 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Selenium
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
,
Interleukin-6 Downregulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substance Synergy
,
Polysaccharides
[+]
Consumption of aronia products may prevent oxidative/antioxidative imbalance induced by cadmium.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2019 ;2019:3403264. Epub 2019 Nov 23. PMID:
31871545
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chokeberry
Diseases
:
Cadmium Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
Problem Substances
:
Cadmium
[+]
Curcumin administration ameliorated the induced effects of aflatoxin B1.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytother Res. 2015 Jan ;29(1):134-40. Epub 2014 Oct 8. PMID:
25639897
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipid Peroxidation
,
Liver Damage: Aflatoxin-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Curcumin and vitamin E were shown to protect rat lungs from oxidative damage.
Sep 16, 2014
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2014 Sep 17. Epub 2014 Sep 17. PMID:
25233897
Article Published Date
: Sep 16, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Vitamin E
Diseases
:
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Curcumin can act as a suitable therapeutic agent against sepsis-induced chronic lung injury.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Health Aging. 2017 ;21(3):307-313. PMID:
28244571
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipid Peroxidation
,
Lung Injury: Acute
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 alpha downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin may be beneficial in the treatment of acute stress induced anxiety and enhancement of memory function.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2015 Jun ;115:1-8. Epub 2015 Apr 11. PMID:
25869755
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Anxiety Disorders
,
Brain Inflammation
,
Stress
Pharmacological Actions
:
Anti-Anxiety Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Curcumin pre-treatment could reduce the effect of radiation on the skin of patients receiving radiotherapy for the treatment of cancer.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2015 ;4(1):25-41. Epub 2015 Jan 13. PMID:
26785336
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Radiotherapy
Pharmacological Actions
:
Antioxidants
,
Radioprotective
,
Superoxide Dismutase Up-regulation
[+]
Curcumin treatment attenuates liver lesions induced by intestinal ischemia/reperfusion.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2014 ;2014:191624. Epub 2014 Aug 20. PMID:
25215173
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Intestinal Ischemia
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Curcumin was shown to have positive effects on lifespan extension in animal studies.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2013 Jan-Feb;39(1):133-40. Epub 2013 Jan 17. PMID:
23325575
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study, Insect Study
Additional Links
Substances
:
Curcumin
,
Tetrahydrocurcumin
Diseases
:
Aging
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Gene Expression Regulation
,
Longevity
[+]
Curcumin-loaded nanocapsules reverses the depressant-like behaviour and oxidative stress induced by β-amyloid.
Jan 14, 2019
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2019 12 15 ;423:122-130. Epub 2019 Nov 4. PMID:
31698022
Article Published Date
: Jan 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Cydonia oblonga Mill. leaf extracts have hypolipidaemic and hepatoprotective effects.
Feb 02, 2014
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2014 Feb 3 ;151(2):970-4. Epub 2013 Dec 14. PMID:
24342780
Article Published Date
: Feb 02, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Quince
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
D-limonene might have a role in the prevention of the complication of diabetes in rats.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2017 Dec ;110:434-442. Epub 2017 Sep 18. PMID:
28923438
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
D-Limonene
Diseases
:
Diabetes: Oxidative Stress
,
Diabetic Complications
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Dandelion has antifibrotic activity in chemically-induced liver damage in mice.
Aug 09, 2010
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Aug 9;130(3):569-77. Epub 2010 Jun 2. PMID:
20561925
Article Published Date
: Aug 09, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Dandelion protects against lipopolysaccharide-induced acute lung injury in mice.
Jul 20, 2010
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Jul 20;130(2):392-7. Epub 2010 May 25. PMID:
20510343
Article Published Date
: Jul 20, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Daucus carota seed extract contributes to the reduction of oxidative stress and the protection of liver in experimental rats.
Apr 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Biomed. 2012 May ;2(5):385-8. PMID:
23569935
Article Published Date
: Apr 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Carrot
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Dietary supplementation with S-adenosyl methionine delays the onset of motor neuron pathology in a murine model of amyotrophic lateral sclerosis.
Feb 28, 2010
Click here to read the entire abstract
Pubmed Data
: Neuromolecular Med. 2010 Mar ;12(1):86-97. Epub 2009 Sep 16. PMID:
19757209
Article Published Date
: Feb 28, 2010
Study Type
: Animal Study
Additional Links
Substances
:
S-Adenosylmethionine (SAMe)
Diseases
:
Amyotrophic Lateral Sclerosis
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
[+]
Diosgenin attenuates vascular calcification in chronic renal failure rats.
May 31, 2013
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2013 Jun ;378(1-2):9-18. Epub 2013 Feb 20. PMID:
23423339
Article Published Date
: May 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Kidney Failure: Chronic
,
Lipid Peroxidation
,
Vascular Calcification
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Diosgenin can inhibit apoptosis and increase mitochondrial oxidative stress capacity of chondrocytes in mice with osteoarthritis.
May 24, 2016
Click here to read the entire abstract
Pubmed Data
: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25 ;45(5):453-460. PMID:
28087904
Article Published Date
: May 24, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Osteoprotective
,
Superoxide Dismutase Up-regulation
[+]
Diosmin ameliorates the effects of oxidative stress in lenses of streptozotocin-induced type 1 diabetic rats.
Sep 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharmacol Rep. 2017 Oct ;69(5):995-1000. Epub 2017 Apr 15. PMID:
28846859
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Diabetes: Cataract
,
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Risk Reduction
[+]
Diosmin pretreatment improves cardiac function and suppresses oxidative stress in rat heart after ischemia/reperfusion.
Aug 04, 2014
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2014 Aug 5 ;736:131-7. Epub 2014 Apr 24. PMID:
24769512
Article Published Date
: Aug 04, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Superoxide Dismutase Up-regulation
[+]
Diosmin protects rat retina from ischemia/reperfusion injury.
Sep 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ocul Pharmacol Ther. 2012 Oct ;28(5):459-66. Epub 2012 Apr 17. PMID:
22509733
Article Published Date
: Sep 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Eye Damage
,
Ischemia
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Effect of anthocyanin-rich tart cherry extract on inflammatory mediators and adipokines involved in type 2 diabetes in a high fat diet induced obesity.
Aug 20, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Aug 21 ;11(9). Epub 2019 Aug 21. PMID:
31438590
Article Published Date
: Aug 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Tart Cherry
Diseases
:
Inflammation
,
Obesity
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Effects of Cydonia oblonga Miller leaf and fruit flavonoids on blood lipids and anti-oxydant potential in hyperlipidemia rats.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2015 Jul 1 ;169:239-43. Epub 2015 Apr 28. PMID:
25934516
Article Published Date
: Jun 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Quince
Diseases
:
Hyperlipidemia
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Effects of emulsion formulations of oleuropein isolated from ethanol extract of olive leaf in diabetic rats.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: An Acad Bras Cienc. 2020 ;92(4):e20190810. Epub 2020 Aug 24. PMID:
32844991
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Effects of exogenous vitamin C on ethanol toxicity in rats.
Sep 30, 2000
Click here to read the entire abstract
Pubmed Data
: Indian J Physiol Pharmacol. 2000 Oct ;44(4):401-10. PMID:
11214494
Article Published Date
: Sep 30, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Alcohol Toxicity
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Effects of kefir on ischemia-reperfusion injury.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur Rev Med Pharmacol Sci. 2015 ;19(5):887-96. PMID:
25807443
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Kefir
Diseases
:
Ischemia
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Effects of the maca extract on the ultrastructures of mitochondria in the spinal nerve cell and exercise endurance.
Jun 07, 2017
Click here to read the entire abstract
Pubmed Data
: Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 Jun 8 ;33(6):535-538. PMID:
29931904
Article Published Date
: Jun 07, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Maca
Diseases
:
Athletic Performance
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Effects of verbascoside and luteolin on oxidative damage in brain of heroin treated mice.
Jun 30, 2005
Click here to read the entire abstract
Pubmed Data
: Pharmazie. 2005 Jul ;60(7):539-43. PMID:
16076083
Article Published Date
: Jun 30, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Luteolin
,
Verbascoside
Diseases
:
Brain: Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Heroin
,
Morphine
[+]
Electroacupuncture pre-treatment alleviates sepsis-induced brain injury by inhibition of microglial activation and attenuation of inflammation.
Oct 18, 2016
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2016 Oct 19 ;127:248-259. Epub 2016 Aug 19. PMID:
27771396
Article Published Date
: Oct 18, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Sepsis
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Catalase Up-Regulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Embelia ribes extract reduces high fat diet and low dose streptozotocin-induced diabetic nephrotoxicity in rats.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: EXCLI J. 2013 ;12:858-71. Epub 2013 Sep 24. PMID:
26622220
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
False Black Pepper
Diseases
:
Diabetes Mellitus: Type 2
,
Diabetic Nephropathy
,
Lipid Peroxidation
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Glutathione Upregulation
,
Insulin Sensitizers
,
Renoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Evaluation of chemopreventive action of Ginsenoside Rp1.
Dec 31, 2005
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2006 ;26(1):29-43. PMID:
16614481
Article Published Date
: Dec 31, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipid Peroxidation
,
Skin Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Superoxide Dismutase Up-regulation
[+]
Exercise training, even in estrogen deficiency conditions, is able to improve endothelial dependent vasodilation in rat aorta.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(4):e0125388. Epub 2015 Apr 29. PMID:
25923465
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Diseases
:
Endothelial Dysfunction
,
Postmenopausal Disorders
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
,
Vasodilator Agents
Additional Keywords
:
Ovariectomy-Induced Changes
[+]
Exposure to ELF-MFs may act as a risk factor for the occurrence of oxidative stress-based nervous system pathologies associated with ageing.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Int J Biochem Cell Biol. 2008 ;40(12):2762-70. Epub 2008 Jun 10. PMID:
18585472
Article Published Date
: Jan 01, 2008
Study Type
: Animal Study
Additional Links
Diseases
:
Aging
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Oxidant
[+]
Fenugreek seed extract reduces cisplatin induced reproductive toxicity in rats by the suppression of testicular oxidative stress, apoptosis and inflammations.
May 20, 2015
Click here to read the entire abstract
Pubmed Data
: Andrologia. 2015 May 21. Epub 2015 May 21. PMID:
25996647
Article Published Date
: May 20, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Fenugreek
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Flax and Pumpkin seeds mixture supplemented in diet of diabetic rats may be helpful to prevent diabetes and its complications.
Jul 31, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2407-12. Epub 2010 Jun 4. PMID:
20570704
Article Published Date
: Jul 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Flaxseed
,
Pumpkin
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
[+]
Fo ti (Polygonum multiflorum) has a protective effect on experimental colitis in mice.
Jan 14, 2008
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2008 Jan 14;578(2-3):339-48. Epub 2007 Oct 25. PMID:
17963744
Article Published Date
: Jan 14, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Fo ti
Diseases
:
Colitis: Pseudomembranous
Pharmacological Actions
:
Malonaldehyde (MDA) Down-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Formononetin has a protective effect on lipopolysaccharide-induced acute lung injury in mice.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2013 Dec ;36(6):1560-6. PMID:
23907652
Article Published Date
: Nov 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Formononetin
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Formononetin mediates the promising anti-traumatic brain injury effects against neurocyte damage.
Mar 14, 2014
Click here to read the entire abstract
Pubmed Data
: J Neurol Sci. 2014 Mar 15 ;338(1-2):112-7. Epub 2013 Dec 27. PMID:
24411660
Article Published Date
: Mar 14, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Formononetin
Diseases
:
Brain Injury: Traumatic
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Fragaria nilgerrensis extract had positive effects on STZ-induced memory dysfunction.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:6938370. Epub 2018 Sep 4. PMID:
30254687
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Strawberry
Diseases
:
Diabetes: Cognitive Dysfunction
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
Fruit pericarp extract of Litchi chinensis was found to delay the progression of diabetic cataractogenesis and retinopathy.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Cutan Ocul Toxicol. 2017 Mar ;36(1):52-59. Epub 2016 May 10. PMID:
27160797
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Lychee
Diseases
:
Advanced Glycation End products (AGE)
,
Diabetes: Cataract
,
Retinopathy: Diabetic
Pharmacological Actions
:
Anti-Glycation Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Fucoidan showed potential neuroprotective effects against Aβ- and d-Gal-induced apoptosis in PC12 cells.
Mar 15, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2017 Mar 16 ;15(3). Epub 2017 Mar 16. PMID:
28300775
Article Published Date
: Mar 15, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
Garlic and allopurinol attenuate hepatic apoptosis induced by fipronil in male albino rats.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Regul Toxicol Pharmacol. 2019 Oct ;107:104400. Epub 2019 May 29. PMID:
31152858
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Catalase Up-Regulation
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Pesticides
[+]
Garlic may effectively modulate antioxidants status in the blood and heart of streptozotocin induced-diabetic rats.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: Acta Physiol Hung. 2015 Dec ;102(4):380-90. PMID:
26690030
Article Published Date
: Nov 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Garlic
Diseases
:
Diabetes Mellitus: Type 1
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Gastrodin ameliorates oxidative stress and proinflammatory response in nonalcoholic fatty liver disease.
Feb 29, 2016
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2016 Mar ;30(3):402-11. Epub 2015 Dec 4. PMID:
26634892
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Gastrodin
Diseases
:
Inflammation
,
Nonalcoholic fatty liver disease (NAFLD)
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Gastrodin prevents motor deficits and oxidative stress in model of Parkinson's disease
Oct 01, 2014
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2014 Oct 2 ;114(2):77-85. Epub 2014 Aug 14. PMID:
25132361
Article Published Date
: Oct 01, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Gastrodin
Diseases
:
Oxidative Stress
,
Parkinson's Disease
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
Genistein protects neurons from lead-induced neurotoxicity.
Feb 29, 2016
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2016 Mar ;53:153-164. Epub 2016 Jan 18. PMID:
26797587
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Genistein
Diseases
:
Lead Poisoning
,
Neurodegenerative Diseases
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Lead
[+]
Gentamicin in combination with ascorbic acid regulates the severity of Staphylococcus aureus infection-induced septic arthritis in mice.
Nov 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Scand J Immunol. 2012 Dec ;76(6):528-40. PMID:
22924656
Article Published Date
: Nov 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Oxidative Stress
,
Staphylococcus aureus infection
Pharmacological Actions
:
Antioxidants
,
Interferon Gamma Reducer
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Antioxidants
,
Natural Substance/Drug Synergy
,
oxidative stress
,
Staphylococcus aureus infection
,
Vitamin C
[+]
Geraniol attenuated important features of allergic asthma in mice.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Ann Allergy Asthma Immunol. 2016 Jun ;116(6):506-13. Epub 2016 Apr 22. PMID:
27117312
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Geraniol
Diseases
:
Asthma
,
Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions
:
Antioxidants
,
Immunomodulatory
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
Ginger protects against dichlorvos and lindane induced oxidative stress in rat brain.
Jan 01, 2012
Click here to read the entire abstract
Pubmed Data
: Pharmacognosy Res. 2012 Jan ;4(1):27-32. PMID:
22224058
Article Published Date
: Jan 01, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
Brain Damage
Pharmacological Actions
:
Glutathione Upregulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Dichlorvos
,
Lindane
[+]
Ginger protects against liver fibrosis.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Nutr Metab (Lond). 2011 ;8:40. Epub 2011 Jun 20. PMID:
21689445
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
Diseases
:
ALT: Elevated
,
AST: Elevated
,
Liver Fibrosis
Pharmacological Actions
:
Glutathione Upregulation
,
Malonaldehyde (MDA) Down-Regulation
,
Renoprotective
,
Superoxide Dismutase Up-regulation
[+]
Ginkgetin may provide neuroprotective therapy for Parkinson's disease and iron metabolism disorder related diseases.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2015 ;49(9):1069-80. Epub 2015 Jul 1. PMID:
25968939
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Iron Overload
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Iron Chelating Agents
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
Ginkgo biloba extract has a protective effects on aging liver.
Jan 06, 2005
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2005 Jan 7 ;11(1):132-5. PMID:
15609412
Article Published Date
: Jan 06, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Aging
,
Aging: Liver
,
Oxidative Stress
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Ginkgolide B attenuated the progressive endothelial and vascular dysfunction in diabetic rats.
Jan 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Croat Med J. 2015 Feb ;56(1):4-13. PMID:
25727037
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Diabetic Complications
,
Endothelial Dysfunction
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
,
Vasodilator Agents
[+]
Ginsenoside Rb1 improves postoperative fatigue syndrome by reducing skeletal muscle oxidative stress.
Oct 04, 2014
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2014 Oct 5 ;740:480-7. Epub 2014 Jun 27. PMID:
24975098
Article Published Date
: Oct 04, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Fatigue
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
[+]
Ginsenoside Rb3 ameliorates myocardial ischemia-reperfusion injury in rats.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2011 Sep ;49(9):900-6. Epub 2011 May 19. PMID:
21591990
Article Published Date
: Aug 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside Rb3 possesses the effect against isoproterenol-induced myocardial injury and heart function impairment.
Jun 24, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2010 Jun 25 ;636(1-3):121-5. Epub 2010 Apr 2. PMID:
20371232
Article Published Date
: Jun 24, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Isoproterenol
[+]
Ginsenoside Rg3 attenuates myocardial ischemia/reperfusion injury.
May 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2015 Jun ;11(6):4518-24. Epub 2015 Feb 11. PMID:
25672441
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Antioxidants
,
Bcl-2 protein down-regulation
,
Cardioprotective
,
Superoxide Dismutase Up-regulation
[+]
Ginsenoside Rg3 improves erectile function in streptozotocin-induced diabetic rats.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: J Sex Med. 2015 Mar ;12(3):611-20. Epub 2014 Dec 1. PMID:
25442300
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Complications
,
Erectile Dysfunction
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Nitric Oxide Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Glutamine and arginine supplementation may help prevent necrotizing enterocolitis.
Jul 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Pediatr Gastroenterol Nutr. 2009 Jul;49(1):85-9. PMID:
19503000
Article Published Date
: Jul 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
,
Glutamine
Diseases
:
Necrotising enterocolitis
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Grape seed extract and zinc containing nutritional food supplement prevents onset and progression of age-related cataract.
Apr 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Nutr Health Aging. 2014 May ;18(5):524-30. PMID:
24886740
Article Published Date
: Apr 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
,
Zinc
Diseases
:
Cataract
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Grape seed proanthocyanidin extract can ameliorate abnormal spermatogenesis and testicular injury in varicocele rats.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Jan ;17(1):1799-1806. Epub 2017 Nov 10. PMID:
29138814
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Oxidative Stress
,
Sperm Count: Low
,
Varicocele
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Heme oxygenase-1 inducer
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
Grape seeds extract provided biochemical and histo-pathological improvement in paracetamol induced renal cortical toxicity.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Bratisl Lek Listy. 2017 ;118(4):233-242. PMID:
28471235
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Acetaminophen (Tylenol) Toxicity
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Green tea catechins confer cardioprotective and radioprotective effects in rats exposed to microwave radiation.
Jan 01, 2004
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2004 ;7(3):299-304. PMID:
15383222
Article Published Date
: Jan 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Antioxidant
,
Antioxidants
,
Cardioprotective
,
Radioprotective
,
Superoxide Dismutase Up-regulation
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
[+]
Green tea could protect against arsenic induced neurotoxicity.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Cent Nerv Syst Agents Med Chem. 2017 Feb 1. Epub 2017 Feb 1. PMID:
28155600
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
Diseases
:
Arsenic Poisoning
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Arsenic
[+]
Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats.
Jul 22, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2019 Jul 23. Epub 2019 Jul 23. PMID:
31364723
Article Published Date
: Jul 22, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
Diseases
:
Insulin Resistance
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Gut microbial status could be crucial for exercise performance and its potential action linked with the antioxidant enzyme system in athletes.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Strength Cond Res. 2015 Feb ;29(2):552-8. PMID:
25144131
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
Additional Keywords
:
Microbiota
[+]
Hepatoprotective effect of methylsulfonylmethane against carbon tetrachloride-induced acute liver injury in rats.
Aug 31, 2013
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2013 Sep ;36(9):1140-8. Epub 2013 Apr 17. PMID:
23591777
Article Published Date
: Aug 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
MSM (Methylsulfonylmethane)
Diseases
:
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Apoptotic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Hepatoprotective effects of allyl isothiocyanate against carbon tetrachloride-induced hepatotoxicity.
Jul 24, 2016
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2016 Jul 25 ;254:102-8. Epub 2016 May 27. PMID:
27241356
Article Published Date
: Jul 24, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Isothiocyanates
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hepatorotective activity of honeysuckle fruit extract in carbon tetrachloride intoxicated rats.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Eksp Klin Farmakol. 2014 ;77(10):26-30. PMID:
25518524
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Honeysuckle
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Hesperidin and chrysin alleviated the renal injury induced by colistin via anti-oxidant and anti-inflammatory activities.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2018 Dec ;108:1607-1616. Epub 2018 Oct 10. PMID:
30372863
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
,
Hesperidin
Diseases
:
Kidney Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Glutathione Upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Humulus japonicus extracts protect against lipopolysaccharide/d-galactosamine-induced acute liver injury in rats.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Oct ;21(10):1009-1015. PMID:
30334699
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Hops
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Huperzine A ameliorates damage induced by acute myocardial infarction.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2014 Jan ;33(1):227-33. Epub 2013 Nov 1. PMID:
24190328
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Huperzine
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hydrogen rich water pre-treatment alleviated the aspirin-induced gastric lesions.
Feb 13, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2014 Feb 14 ;20(6):1614-22. PMID:
24587639
Article Published Date
: Feb 13, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Aspirin-Induced Toxicity
,
Gastrointestinal Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Gastroprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Aspirin
[+]
Hydrogen-rich water could suppress gingival oxidative stress and alveolar bone resorption by limiting obesity.
Jan 12, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Jan 13 ;9(1). Epub 2017 Jan 13. PMID:
28098768
Article Published Date
: Jan 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
High Fat Diet
,
Obesity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Anti-Obesity Agents
[+]
Hydrogen-rich water protects against chronic ethanol-induced liver injury.
Jul 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2017 Jul 21 ;23(27):4920-4934. PMID:
28785146
Article Published Date
: Jul 20, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hydroxysafflor yellow A exerts beneficial effects by restoring hormone secretion and alleviating oxidative stress in polycystic ovary syndrome.
Dec 31, 2019
Click here to read the entire abstract
Pubmed Data
: Exp Physiol. 2020 02 ;105(2):282-292. Epub 2020 Jan 14. PMID:
31803965
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Safflower
Diseases
:
Polycystic Ovary Syndrome
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Hydroxysafflor yellow A exerts antioxidant effects in a rat model of traumatic brain injury.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Oct ;14(4):3690-6. Epub 2016 Sep 6. PMID:
27599591
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Safflower
Diseases
:
Brain: Oxidative Stress
,
Brain Injury: Traumatic
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
In vitro and ex vivo anti-diabetic and anti-hyperglycemic properties of Zataria multiflora essential oil.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2020 Oct ;47(10):7805-7813. Epub 2020 Oct 1. PMID:
33006014
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Zataria multiflora
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Hypoglycemic Agents
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
In vitro and in vivo antioxidant activities of a flavonoid isolated from celery.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2014 Jan ;5(1):50-6. PMID:
24232123
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Celery
,
Flavonoids
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Influence of boron supplementation on performance, immunity and antioxidant status of lambs fed diets with or without adequate level of calcium.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(11):e0187203. Epub 2017 Nov 15. PMID:
29141035
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Boron
Pharmacological Actions
:
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Intermittent fasting increases the expressions of superoxide dismutase and catalase in the adult gerbil dentate gyrus.
Jan 03, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2019 Jan 4. Epub 2019 Jan 4. PMID:
30628688
Article Published Date
: Jan 03, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Oxidative Stress
Therapeutic Actions
:
Fasting/Caloric Restriction
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
[+]
Isolation of a wild Morchella spp. strain and the effects of its extract on ethanol-induced gastric mucosal lesions in rats.
Dec 31, 2010
Click here to read the entire abstract
Pubmed Data
: Z Naturforsch C. 2011 Jan-Feb;66(1-2):55-62. PMID:
21476437
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Mushrooms: All
Diseases
:
Alcohol Toxicity
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Ketogenic diet improves and restores redox status and biochemical indices in monosodium glutamate-induced rat testicular toxicity.
May 16, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2020 May 17 ;127:110227. Epub 2020 May 17. PMID:
32434144
Article Published Date
: May 16, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Testicular Injury: Chemical/Metal Induced
Therapeutic Actions
:
Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Monosodium Glutamate (MSG)
[+]
L-arginine has potent in vitro and in vivo neuroprotective properties and may be a candidate for therapeutic trials in ALS.
Jul 10, 2009
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2009 Jul 10;384(4):524-9. Epub 2009 May 8. PMID:
19427829
Article Published Date
: Jul 10, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
Diseases
:
Amyotrophic Lateral Sclerosis
Pharmacological Actions
:
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
L-arginine prevents endothelial dysfunction in rats with chronic renal failure.
Mar 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2007 Mar;49(3):131-9. PMID:
17414224
Article Published Date
: Mar 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
Diseases
:
Endothelial Dysfunction
,
Hypertension
,
Kidney Failure: Chronic
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
,
Vasodilator Agents
Additional Keywords
:
Drug Synergy
[+]
L-arginine protects against pulmonary oxidative stress and antioxidant defenses during exhaustive exercise in rats.
Aug 01, 2005
Click here to read the entire abstract
Pubmed Data
: Acta Pharmacol Sin. 2005 Aug;26(8):992-9. PMID:
16038634
Article Published Date
: Aug 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Arginine
Diseases
:
Exercise-Induced Tissue Damage
,
Lipid Peroxidation
,
Lung Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Glutathione Upregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Lactobacillus reuteri DSM 17938 protects against gastric damage induced by ethanol.
Jan 20, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Jan 21 ;11(1). Epub 2019 Jan 21. PMID:
30669695
Article Published Date
: Jan 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus reuteri
Diseases
:
Alcohol Toxicity
,
Gastric Ulcer
Pharmacological Actions
:
Antioxidants
,
Gastroprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Lactobacillus rhamnosus CCFM1107 treatment ameliorates alcohol-induced liver injury in a mouse model of chronic alcohol feeding.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: J Microbiol. 2015 Dec ;53(12):856-63. Epub 2015 Dec 2. PMID:
26626356
Article Published Date
: Nov 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus rhamnosus
Diseases
:
Alcohol Toxicity
,
Alcoholic Liver Disease
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Light-emitting diode therapy reduces persistent inflammatory pain.
Mar 17, 2016
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2016 Mar 18 ;324:485-495. Epub 2016 Mar 18. PMID:
27001179
Article Published Date
: Mar 17, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Inflammation
,
Pain
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Interleukin-10 upregulation
,
Superoxide Dismutase Up-regulation
[+]
Lignan transformation by gut bacteria lowers tumor burden in a gnotobiotic rat model of breast cancer.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Carcinogenesis. 2012 Jan ;33(1):203-8. Epub 2011 Nov 10. PMID:
22080573
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Lignan-converting bacteria
,
Lignans
,
Secoisolariciresinol diglucoside (SDG)
Diseases
:
Breast Cancer
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
Additional Keywords
:
Bacterial Biotransformation
[+]
Lingonberry extract improved the cognition and memory of the mice induced by chronic uncertainty stress.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Wei Sheng Yan Jiu. 2015 Nov ;44(6):943-8. PMID:
26738388
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lingonberry
Diseases
:
Memory Disorders
,
Oxidative Stress
,
Stress
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Loganin improved diabetic nephropathy in vivo.
Feb 14, 2015
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2015 Feb 15 ;123:78-85. Epub 2015 Jan 23. PMID:
25623853
Article Published Date
: Feb 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Dogwood
Diseases
:
Advanced Glycation End products (AGE)
,
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Glycation Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Lotus seedpod procyanidins mitigate the oxidative effects and learning and memory damage caused by extremely low frequency electromagnetic fields on
Aug 01, 2013
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2013 Aug ;4(8):1252-62. PMID:
23764910
Article Published Date
: Aug 01, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Lotus
Diseases
:
Learning disorders
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
,
Proanthocyanidins
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Neurotoxic
,
Oxidant
[+]
Lutein can improve antioxidation function and has protective effect on liver injury of mice induced by arsenic.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: Wei Sheng Yan Jiu. 2015 Jul ;44(4):615-9. PMID:
26454960
Article Published Date
: Jun 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lutein
Diseases
:
Arsenic Poisoning
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Lychee pulp phenolics protect the liver against restraint stress-induced damage by scavenging free radicals and modulating mitochondrial dysfunction.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Jan ;7(1):508-15. PMID:
26569420
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Litchi
Diseases
:
Liver Damage
,
Mitochondrial Dysfunction
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Glutathione Upregulation
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Antioxidants
,
Catalase Up-Regulation
,
Litchi
,
liver damage
,
Mitochondrial Dysfunction
,
oxidative stress
,
Plant Extracts
[+]
Lycopene attenuates AFB1-induced renal injury with the activation of the Nrf2 antioxidant signaling pathway in mice.
Dec 12, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 Dec 13 ;9(12):6427-6434. PMID:
30462120
Article Published Date
: Dec 12, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene
Diseases
:
Kidney Damage: Chemically-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Renoprotective
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Aflatoxin
[+]
Lycopene may be a potential functional food alternative for controlling and treating epileptic seizures.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Epilepsy Res. 2019 03 ;151:1-6. Epub 2019 Jan 17. PMID:
30669043
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene
Diseases
:
Epilepsy
,
Seizures
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Lycopene protects against renal cortical damage induced by nandrolone decanoate.
Jun 30, 2019
Click here to read the entire abstract
Pubmed Data
: Ann Anat. 2019 Jul ;224:142-152. Epub 2019 May 17. PMID:
31108192
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene
Diseases
:
Oxidative Stress
,
Steroid-Induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Renoprotective
,
Superoxide Dismutase Up-regulation
[+]
Lycopene significantly combated sodium fluoride induced ameloblasts apoptosis and dental fluorosis.
Nov 17, 2016
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2016 Nov 18 ;261:27-34. Epub 2016 Nov 18. PMID:
27871895
Article Published Date
: Nov 17, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene
Diseases
:
Fluoride Toxicity
,
Fluorosis
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Sodium Fluoride
[+]
Lyophilized black raspberries may offer an advantage in cancer prevention by targeting multiple signalling pathways.
Apr 21, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Apr 22 ;9(4). Epub 2017 Apr 22. PMID:
28441719
Article Published Date
: Apr 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Black Raspberry
Diseases
:
Esophageal Cancer
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Chemopreventive
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Matcha green tea has beneficial effects through the suppression of the blood glucose accumulation and promotion of the lipid metabolism and antioxidant activities.
Oct 07, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Oct 8. Epub 2015 Oct 8. PMID:
26448271
Article Published Date
: Oct 07, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
Diseases
:
High Fat Diet
Pharmacological Actions
:
Antioxidants
,
Hypoglycemic Agents
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Mechanisms underlying gastroprotective effect of paeonol against indomethacin-induced ulcer in rats.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2019 May ;38(5):510-518. Epub 2018 Dec 24. PMID:
30580614
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Paeonol
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Anti-Ulcer Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Malondialdehyde Down-regulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Indomethacin
[+]
Melatonin and caffeic acid phenethyl ester prevent renal tubular injury by reducing oxidative stress and protect the kidney from oxidative damage induced by 900 MHz mobile phone.
Aug 01, 2005
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2005 Aug ;276(1-2):31-7. PMID:
16132682
Article Published Date
: Aug 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
,
Melatonin
Diseases
:
Radiation Induced Illness
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
Adverse Pharmacological Actions
:
Nephrotoxic
[+]
Melatonin attenuates sepsis induced brain injury via activation SIRT1 signaling activation.
Jun 09, 2015
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2015 Jun 10. Epub 2015 Jun 10. PMID:
26094939
Article Published Date
: Jun 09, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Brain: Oxidative Stress
,
Brain Inflammation
,
Sepsis
,
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
SIRT1 Activator
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Significant Treatment Outcome
[+]
Melatonin has a protective effect against formaldehyde-induced oxidative damage and apoptosis in rat testes.
Jun 30, 2008
Click here to read the entire abstract
Pubmed Data
: Syst Biol Reprod Med. 2008 Jul-Aug;54(4-5):169-76. PMID:
18942024
Article Published Date
: Jun 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Oxidative Stress
,
Testicular Injury: Formaldehyde-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Melatonin reduces age-related oxidaitve stress in the brain of age-accelerated mice.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2009 Jan;46(1):106-14. PMID:
19090913
Article Published Date
: Jan 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Aging: Brain
,
Oxidative Stress
Pharmacological Actions
:
Apoptotic
,
Bcl-2 protein down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
Melittin efficiently reduced paraquat-induced lung injuries.
Apr 15, 2019
Click here to read the entire abstract
Pubmed Data
: Molecules. 2019 Apr 16 ;24(8). Epub 2019 Apr 16. PMID:
30995821
Article Published Date
: Apr 15, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bee Venom
Diseases
:
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Apoptotic
,
Bcl-2 protein down-regulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Paraquat
[+]
Miroestrol, a phytoestrogen from Pueraria mirifica, improves the antioxidation state in the livers and uteri of β-naphthoflavone-treated mice.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2014 Jan ;68(1):173-80. Epub 2013 Jun 28. PMID:
23812874
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Pueraria mirifica
Diseases
:
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
[+]
Moderate intake of Sambucus willamsii Hance fruit oil exhibits a significantly protective effect on acute liver injury.
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Wei Sheng Yan Jiu. 2018 May ;47(3):437-464. PMID:
30082013
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Elderberry
Diseases
:
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Modified citrus pectin stops progression of liver fibrosis by inhibiting galectin-3.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2016 May ;94(5):554-62. Epub 2015 Aug 16. PMID:
27010252
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Modified Citrus Pectin
Diseases
:
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Superoxide Dismutase Up-regulation
[+]
Moringa oleifera leaf extract lowers high blood pressure by alleviating vascular dysfunction and decreasing oxidative stress.
Feb 14, 2019
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2019 Feb 15 ;54:9-16. Epub 2018 Oct 19. PMID:
30668387
Article Published Date
: Feb 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Hypertension
,
Oxidative Stress
Pharmacological Actions
:
Antihypertensive Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Moringa oleifera seed extract can be used as herbal medication against HFD induced ROS mediated disorders.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: Indian J Exp Biol. 2015 Dec ;53(12):794-802. PMID:
26742324
Article Published Date
: Nov 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
High Fat Diet
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Musa sapientum extract inhibited protein glycation, regenerated the islet cells and improved erythrocyte antioxidant status in diabetic rats.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Afr J Med Med Sci. 2015 Sep ;44(3):261-8. PMID:
27280239
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Banana
,
Banana Leaf
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Glycation Agents
,
Antioxidants
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Musk melon leaf extract exerts a neuroprotective effect against oxidative damage associated with diabetes.
Aug 02, 2016
Click here to read the entire abstract
Pubmed Data
: Metab Brain Dis. 2016 Aug 3. Epub 2016 Aug 3. PMID:
27488111
Article Published Date
: Aug 02, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Muskmelon
Diseases
:
Diabetes: Oxidative Stress
,
Diabetic Complications
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Myricetin ameliorates the cardiotoxic effects of isoproterenol and may be of value in the treatment of myocardial infarction.
Sep 30, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Oct ;23(10):1361-6. PMID:
19306480
Article Published Date
: Sep 30, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Myricetin
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Catalase Up-Regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Isoproterenol
[+]
Myricetin exerted a significant protective role against high choline diet induced endothelial dysfunction and liver injury in mice.
May 12, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 May 13 ;6(5):1620-34. PMID:
25881982
Article Published Date
: May 12, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Myricetin
Diseases
:
Chemically-Induced Liver Damage
,
Endothelial Dysfunction
Pharmacological Actions
:
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Choline
,
High Choline Diet
[+]
Myrtle significantly diminishes burn-induced damage in skin.
Jan 11, 2019
Click here to read the entire abstract
Pubmed Data
: Burns. 2019 12 ;45(8):1856-1863. Epub 2019 Aug 3. PMID:
31383607
Article Published Date
: Jan 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Myrtle
Diseases
:
Burns
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
N sativa may protect brain and medulla spinalis tissues against oxidative stress induced by experimental autoimmune encephalomyelitis.
Sep 04, 2005
Click here to read the entire abstract
Pubmed Data
: Cell Mol Biol (Noisy-le-grand). 2005 Sep 5 ;51(3):337-42. Epub 2005 Sep 5. PMID:
16191402
Article Published Date
: Sep 04, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Encephalomyelitis
,
Multiple Sclerosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
N-acetylcysteine and thymoquinone have renoprotective effects of against the toxicity of fluoride via multiple mechanisms.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2018 ;2018:5614803. Epub 2018 Jun 28. PMID:
30050936
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Thymoquinone
Diseases
:
Fluoride Toxicity
,
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Glutathione Upregulation
,
Nrf2 activation
,
Renoprotective
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Sodium Fluoride
[+]
N-acetylcysteine pretreatment ameliorates mercuric chloride-induced oxidative renal damage.
Nov 30, 2010
Click here to read the entire abstract
Pubmed Data
: Afr J Med Med Sci. 2010 Dec ;39 Suppl:153-60. PMID:
22416658
Article Published Date
: Nov 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Lipid Peroxidation
,
Mercury Poisoning
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Renoprotective
,
Superoxide Dismutase Up-regulation
[+]
N. sativa and thymoquinone may prove clinically useful in the treatment of diabetics and in the protection of β-cells against oxidative stress.
Nov 30, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Diabetes. 2010 Dec ;2(4):256-66. PMID:
20923501
Article Published Date
: Nov 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Diabetes: Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Pancreato Protective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Antioxidants
,
Diabetes: Oxidative Stress
,
Nigella sativa (aka Black Seed)
,
Phytotherapy
,
Plant Extracts
,
thymoquinone
[+]
N. sativa exerts a protective effect against cadmium toxicity.
Nov 30, 2005
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2005 Dec ;107(3):277-87. PMID:
16286683
Article Published Date
: Nov 30, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Cadmium Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Naringenin has a cardioprotective effect against ischemia-reperfusion injury.
Apr 18, 2016
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2016 Apr 19:1-6. Epub 2016 Apr 19. PMID:
27408985
Article Published Date
: Apr 18, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Naringenin
Diseases
:
Ischemia: Myocardial
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Naringin has a protective effect against Intracerebral hemorrhage-induced neurocognitive deficits.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacology. 2017 ;100(3-4):172-187. Epub 2017 Jul 1. PMID:
28668949
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Citrus naringin
Diseases
:
Cerebral Hemorrhage
,
Hyperalgesia
,
Lipid Peroxidation
Pharmacological Actions
:
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Nephroprotection of plantamajoside in rats treated with cadmium.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2015 Jan ;39(1):125-36. Epub 2014 Nov 30. PMID:
25499790
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Plantago asiatica
Diseases
:
Cadmium Poisoning
,
Kidney Damage: Chemically-Induced
,
Lipid Peroxidation
Pharmacological Actions
:
Renoprotective
,
Superoxide Dismutase Up-regulation
[+]
Neural progenitors derived from human induced pluripotent stem cells survive and differentiate upon transplantation into a rat model of amyotrophic lateral sclerosis.
Feb 28, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Stem Cells Transl Med. 2013 Mar ;2(3):167-74. Epub 2013 Feb 14. PMID:
23413376
Article Published Date
: Feb 28, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Amyotrophic Lateral Sclerosis
Therapeutic Actions
:
Stem Cell Related Therapy
Pharmacological Actions
:
Superoxide Dismutase Up-regulation
[+]
Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats.
Feb 09, 2005
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2005 Feb 10 ;374(2):92-7. PMID:
15644271
Article Published Date
: Feb 09, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
,
Middle Cerebral Artery Occlusion (MCAO)
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
[+]
Neuroprotective effect of a standardized extract of Centella asiatica ECa233 in rotenone-induced parkinsonism.
May 14, 2018
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2018 May 15 ;44:65-73. Epub 2018 Apr 16. PMID:
29895494
Article Published Date
: May 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,