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Interleukin-6 Downregulation
Views 3490
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427 Substances Researched for Interleukin-6 Downregulation
Name
AC
CK
Focus
Curcumin
62
145
Coenzyme Q10
11
116
Vitamin C
16
96
Probiotics
11
74
Berberine
25
56
Ginsenosides
28
53
Resveratrol
24
42
Vitamin D
8
37
Spirulina
5
36
Melatonin
6
35
Alpha-Lipoic Acid
4
34
Lycopene
4
33
Astaxanthin
12
32
Garlic
3
32
Polyphenols
19
32
Thymoquinone
16
32
Omega-3 Fatty Acids
4
31
Tomato
2
30
Ginger
15
28
Lactobacillus plantarum
6
27
Fish Oil
4
26
Flavonoids
15
26
Anthocyanins
9
25
Green Tea
13
24
Red Sage
9
24
Vitamin E
4
24
Paeoniflorin
13
23
Puerarin
9
23
Quercetin
14
23
Sesame Seeds
4
23
Tanshinone IIA
15
23
Luteolin
12
22
Strawberry
3
22
Gastrodin
7
21
Turmeric
9
21
Hesperidin
11
20
Isoflavones
2
20
Purslane
11
20
Soy Protein
2
20
Vitamin B-12
2
20
Rose
12
19
Citrus naringin
10
18
EGCG (Epigallocatechin gallate)
10
18
Asiatic Acid
11
17
Lactobacillus fermentum
5
17
Sulforaphane
12
17
Astragaloside
10
16
Genistein
5
16
Lactobacillus casei
4
16
Moringa oleifera
10
16
Vitamin E: alpha tocopherol
4
16
DHA (Docosahexaenoic Acid)
4
15
Black Raspberry
4
14
Dandelion
8
14
Nettle
3
14
Phloretin
7
14
Pomegranate
5
14
Silibinin
3
14
Whey
3
14
Black Currant
3
13
Cannabidiol
7
13
Fisetin
5
13
Ginkgo biloba
3
13
Lychee
5
13
Oleuropein
5
13
Panax Notoginseng
7
13
Rosmarinic acid
5
13
Burdock
2
12
Caffeic acid phenethyl ester
2
12
Cyanidin 3-glucoside
2
12
Fucoidan
6
12
Honey
2
12
Indole-3-Carbinol
6
12
Lactobacillus probiotics
2
12
Magnolol
6
12
NAC (N-acetyl-L-cysteine)
2
12
Olive Oil
2
12
Tart Cherry
2
12
Yerba Mate
2
12
Astragalus
2
11
Boswellia
2
11
Chrysanthemum Indicum
6
11
Ellagic Acid
7
11
Ginseng (Korean)
7
11
Lactobacillus delbrueckii Subsp
2
11
Lotus
6
11
Lutein
2
11
Nobiletin
7
11
Nuts
2
11
Punicalagin
5
11
Sesamin
2
11
Almond
1
10
Antioxidant formulas
1
10
Ashwagandha
6
10
Bacillus coagulans
1
10
Baicalein
5
10
Bee Venom
6
10
Bilberry
1
10
Blueberry
6
10
Broccoli Sprouts
1
10
Carnitine
1
10
Chocolate
1
10
Cruciferous Vegetables
1
10
Delphinidin
1
10
Flaxseed
1
10
Folate
1
10
Folic Acid
1
10
Hydrogen Water
5
10
Isothiocyanate
1
10
Kaempferol
6
10
Lactobacillus Acidophilus
1
10
Lactobacillus reuteri
5
10
Mastic gum
1
10
Pumpkin Seeds
1
10
Raisins
1
10
Soup
1
10
Thunder god vine
1
10
Tripterygium wilfordii
1
10
Ubiquinol
1
10
Vitamin A
1
10
Water: Electrolyzed Reduced
1
10
beta-Carotene
1
10
Carnosol
3
9
Fucoxanthin
5
9
Grape Seed Extract
5
9
Honokiol
5
9
Lactobacillus rhamnosus GG
5
9
Bamboo
3
8
Chrysin
6
8
Crocin
4
8
Ferulic acid
4
8
Myricetin
5
8
Tangeretin
5
8
Wogonin
6
8
Apigenin
4
7
Chokeberry
4
7
Diosmin
4
7
Genipin
4
7
Ginseng
2
7
Ligustrazine
4
7
Naringenin
4
7
Piceatannol
5
7
Sea buckthorn
4
7
Selenium
4
7
Stilbenes
4
7
Vitexins
2
7
6-Shogaol
3
6
Agaricus Blazei
3
6
Allicin
3
6
Carnosic Acid
3
6
Chlorogenic Acid
3
6
Eucalyptus
3
6
Hibiscus sabdariffa
3
6
Histidine
3
6
Kefir
3
6
Mangiferin
4
6
Manuka Honey
4
6
Rooibos
3
6
Rosemaric Acid
4
6
Sweet Potato: Purple
4
6
Verbascoside
4
6
Yellow Tea
3
6
Adlay
4
5
Beta-Elemene
3
5
Betulinic acid
3
5
Gallic Acid
3
5
Garlic: Aged
1
5
Gingerol
3
5
Gotu Kola
3
5
Guduchi
3
5
Hops
3
5
Isoliquiritigenin
3
5
Japanese cypress
3
5
Lactobacillus rhamnosus
3
5
Olive
3
5
Piperine
3
5
Rutin
3
5
Saffron
3
5
Shikonin
3
5
Acai
2
4
Aloe Vera
2
4
Amygdalin
2
4
Bifidobacterium Longum
2
4
Bitter Apple
2
4
Bitter Melon
2
4
Camel Milk
2
4
Carnosine
2
4
Chinese Skullcap
2
4
Cocoa
2
4
Diosgenin
2
4
EPA (Eicosapentaenoic Acid)
2
4
Emodin
2
4
Hu Zhang (Polygonum cuspidatum)
2
4
Huperzine
2
4
Isothiocyanates
3
4
Mulberry
2
4
Patchouli
2
4
Propolis: Bee
2
4
Purple Carrots
3
4
Red Yeast Rice
2
4
Sesamol
2
4
Soy
2
4
St. Johns Wort
2
4
Vanillin
3
4
White Tea
2
4
Xanthohumol
2
4
Zerumbone
2
4
Arctigenin
2
3
Artichoke
2
3
Bacopa
2
3
Bergamot
2
3
Bitter Orange
2
3
Black Tea
2
3
Chamomile
2
3
Cucurbitacin B
2
3
Curcumin: Degradiation byproducts
2
3
Echinacea
3
3
Eugenol
2
3
Garcinia Mangostana
2
3
Geraniol
2
3
Glycyrrhizin
2
3
Hemp Seed
2
3
Jujube
2
3
Justicia gendarussa
2
3
Lignans
2
3
Lion's Mane (Hericium Erinaceus)
2
3
Loquat Leaves
2
3
MSM (Methylsulfonylmethane)
2
3
Nigella sativa (aka Black Seed)
2
3
Oats
2
3
P-Coumaric Acid
2
3
Parthenolide
2
3
Perilla
2
3
Persimmon
2
3
Plantago
2
3
Procyanidin B2
2
3
Raspberry
2
3
Reishi Mushroom
3
3
Soybean: Black
2
3
Theaflavins
2
3
Thyme
2
3
Thymol
2
3
Vitex negundo
2
3
Yoghurt
2
3
Zeaxanthin
2
3
ALA (Alpha-Linolenic Acid)
1
2
Aduki bean
1
2
African Basil
1
2
Alpha Linolenic Acid
1
2
Angelica
1
2
Antrodia Camphorate
1
2
Apocynin
1
2
Arginine
1
2
Artesunate
1
2
Bael
1
2
Banaba
1
2
Banana
1
2
Barberry
1
2
Barley
1
2
Basil
1
2
Beans: All
1
2
Beta-Caryophyllene
1
2
Bifidobacterium
1
2
Bifidobacterium Infantis
1
2
Billygoat Weed
1
2
Blackberry
1
2
Blue Honeysuckle
1
2
Boron
1
2
Brown Rice
1
2
Brown Rice: Pre-Germinated
1
2
Buckwheat
1
2
Butyrate
1
2
Caffeic Acid
1
2
Cardamonin
1
2
Carnosine
1
2
Catechin
1
2
Celadrin
1
2
Chaenomeles speciosa
1
2
Chaga Mushroom (Inonotus obliquus)
1
2
Chia
1
2
Cinnamaldehyde
2
2
Cinnamon
1
2
Citrulline
1
2
Citrus Peel
1
2
Coconut Oil
1
2
Coffee: Green/Unroasted
1
2
Corn: Purple
1
2
Cranberry
1
2
Crocetin
1
2
Cystine
1
2
Diallyl sulfide
1
2
Elderberry
1
2
Elm tree
1
2
Evening Primrose Oil
1
2
FOS (Fructooligosaccharides)
1
2
Flaxseed Oil
1
2
Garden Cress (Lepidium sativum)
1
2
Gold (nanoparticles)
1
2
Grape
1
2
Gymnema Sylvestre
1
2
Hawthorn
1
2
Helenalin
1
2
Kaempferia parviflora
1
2
Krill
1
2
L-Carnitine
1
2
Lactobacillus Brevis
1
2
Lactobacillus paracasei
1
2
Lactobacillus salivarius
1
2
Lemon Verbena
1
2
Litchi
1
2
Loquat
1
2
Lupeol
1
2
Maca
1
2
Maitake Mushroom
1
2
Milk Thistle
1
2
Milk: Fermented
1
2
Mint
1
2
Mosla scabra
1
2
Moxibustion
1
2
Mucuna pruriens (aka Velvet Beans)
1
2
Mussel: Green-lipped (Perna canaliculus)
1
2
Myrrh
1
2
Nattokinase
1
2
Neem
1
2
Oleanolic acid
1
2
Olive leaf extract
1
2
Onion
1
2
Oolong tea
1
2
Palmitoylethanolamide
1
2
Peony
1
2
Perillaldehyde
1
2
Phosphatidylcholine
1
2
Phytosterols
1
2
Pine Needle
2
2
Piper cubeba (Cubeb)
1
2
Pomegranate Peel
1
2
Potato
1
2
Prunella vulgaris
1
2
Pterostilbene
1
2
Rice
1
2
Satsuma
1
2
Sembung Leaf
1
2
Sesame Seed Oil
1
2
Shiitake Mushroom
1
2
Silymarin
1
2
Sour Cherry
2
2
Spikenard
2
2
Stevia
1
2
Suma (Pfaffia Paniculata)
1
2
Tea
1
2
Tetrahydrocurcumin
1
2
Theanine
1
2
Tocotrienols
1
2
Velvet antler
1
2
Vitamin K
1
2
Vitamin K2: (MK-4)
1
2
White Mulberry
2
2
Yeast
1
2
Acorus calamus
1
1
Agrimony
1
1
Amino Acids
1
1
Amygdalin (laetrile)
1
1
Andrographis
1
1
Antrodia camphorata
1
1
Apple Cider Vinegar
1
1
Apple Pectin
1
1
Avocado
1
1
Ayahuasca
1
1
Basil: Sweet
1
1
Beta-glucan
1
1
Bisdemethoxycurcumin
1
1
Bromelain
1
1
Caffeoylquinic Acids
1
1
Carotenoids
1
1
Celery seed
1
1
Chlorella (Algae)
1
1
Coriandrum sativum
1
1
Cranberry Proanthocyanidins
1
1
Cryptomeria japonica
1
1
Cucurbitacin E
1
1
Curcumin: Lipidated
1
1
Daidzein
1
1
Damnacanthal
1
1
Delta-tetrahydrocannabinol (THC)
1
1
Devils Claw
1
1
Frankincense
1
1
Fruit: All
1
1
Gynostemma
1
1
Hirudin (from Medicinal Leaches)
1
1
Horseradish
1
1
Horsetail
1
1
Juniper
1
1
Kombucha Tea
1
1
Maple
1
1
Maple Syrup
1
1
Meadowsweet
1
1
Medicinal Mushrooms
1
1
Motherwort
1
1
Mushrooms: All
1
1
Oak
1
1
Palash
1
1
Phellinus Linteus
1
1
Pine Cone
1
1
Polyacetylenes
1
1
Polyunsaturated Fatty Acids (PUFAs)
1
1
Pomegranate flower
1
1
Prickly Pear Cactus
1
1
Progesterone
1
1
Red Clover
1
1
Rhubarb
1
1
Riboflavin (Vitamin B-2)
1
1
Rice: Black
1
1
Royal Jelly
1
1
Saccharomyces Boulardii
1
1
Salicylic acid
1
1
Sessile Joyweed
1
1
Sophora Flavescens
1
1
Sumac
1
1
Syrian rue
1
1
Thistle
1
1
Ursolic Acid
1
1
Vegetables: All
1
1
Vitamin E: Gamma-tocotrienol
1
1
Wasabi
1
1
Willow Bark
1
1
Wormwood
1
1
Zataria multiflora
1
1
Research Articles
1144
Cumulative Knowledge Score
1850
Overall Research Rating
EXCELLENT
View the Evidence:
1945 Abstracts with Interleukin-6 Downregulation Research
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[+]
Alpha-lipoic acid supplementation had beneficial effects on inflammatory markers among patients with metabolic syndrome and related disorders.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2018 ;15:39. Epub 2018 Jun 5. PMID:
29930690
Article Published Date
: Dec 31, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
C-Reactive Protein
,
Inflammation
,
Metabolic Syndrome X
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Coenzyme Q10 could have significant inflammatory lowering effects.
Feb 04, 2017
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 Feb 5 ;119:128-136. Epub 2017 Feb 5. PMID:
28179205
Article Published Date
: Feb 04, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
C-Reactive Protein
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Coenzyme Q10 supplementation may partly improve the process of inflammatory state.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(1):e0170172. Epub 2017 Jan 26. PMID:
28125601
Article Published Date
: Dec 31, 2016
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary probiotics are effective in improving the symptoms of inflammatory bowel disease.
Nov 26, 2019
Click here to read the entire abstract
Pubmed Data
: J Dairy Sci. 2019 Nov 27. Epub 2019 Nov 27. PMID:
31785874
Article Published Date
: Nov 26, 2019
Study Type
: Meta Analysis
Additional Links
Substances
:
Probiotics
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Flaxseed supplementation may improve some circulating concentrations of specific adhesion molecules and inflammatory cytokines.
Nov 14, 2019
Click here to read the entire abstract
Pubmed Data
: Cytokine. 2019 Nov 15 ;126:154922. Epub 2019 Nov 15. PMID:
31739218
Article Published Date
: Nov 14, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Flaxseed
Diseases
:
Endothelial Dysfunction
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Garlic supplementation reduces circulating C-reactive protein, tumor necrosis factor, and interleukin-6 in adults.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2019 Apr 1 ;149(4):605-618. PMID:
30949665
Article Published Date
: Mar 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Garlic
Diseases
:
C-Reactive Protein
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Meta-analysis: curcumin down-regulates inteleukin-6.
Jul 04, 2016
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2016 Jul 5. Epub 2016 Jul 5. PMID:
27392742
Article Published Date
: Jul 04, 2016
Study Type
: Meta Analysis
Additional Links
Substances
:
Curcumin
Diseases
:
Inflammation
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Mind-body therapies reduce markers of inflammation and influence virus-specific immune responses to vaccination.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(7):e100903. Epub 2014 Jul 2. PMID:
24988414
Article Published Date
: Dec 31, 2013
Study Type
: Meta Analysis
Additional Links
Diseases
:
C-Reactive Protein
,
Inflammation
Therapeutic Actions
:
Mind-Body Therapies
,
Tai Chi
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Probiotic supplementation significantly reduced serum concentrations of pro-inflammatory cytokines.
Mar 10, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2019 Mar 11. Epub 2019 Mar 11. PMID:
30854594
Article Published Date
: Mar 10, 2019
Study Type
: Meta Analysis
Additional Links
Substances
:
Probiotics
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-12 downregulation
,
Interleukin-4 downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Probiotics lowered pro-inflammatory cytokines IL-6 in rheumatoid arthritis.
Sep 14, 2017
Click here to read the entire abstract
Pubmed Data
: Clin Rheumatol. 2017 Sep 15. Epub 2017 Sep 15. PMID:
28914373
Article Published Date
: Sep 14, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Probiotics
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Prolonged vitamin C supplementation has some modest beneficial effects on recovery from unaccustomed exercise.
Nov 30, 2001
Click here to read the entire abstract
Pubmed Data
: Int J Sport Nutr Exerc Metab. 2001 Dec ;11(4):466-81. PMID:
11915781
Article Published Date
: Nov 30, 2001
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin C
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
Additional Keywords
:
Demanding Exercise
,
Prolonged Vitamin C Supplementation
,
Recovery
[+]
Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Eur Rev Med Pharmacol Sci. 2017 May ;21(10):2473-2481. PMID:
28617537
Article Published Date
: Apr 30, 2017
Study Type
: Meta Analysis
Additional Links
Substances
:
Spirulina
Diseases
:
Hypertension
,
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
,
Insulin Sensitizers
,
Interleukin-6 Downregulation
[+]
Supplementation of fish oil may reduce the circulating levels of TNF-α, IL-1 and IL-6 in patients with chronic heart failure.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Cardiovasc Disord. 2012 ;12:77. Epub 2012 Sep 20. PMID:
22994912
Article Published Date
: Dec 31, 2011
Study Type
: Meta Analysis
Additional Links
Substances
:
Fish Oil
Diseases
:
C-Reactive Protein
,
Heart Failure
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The effects of NAC on amending TNF-α and IL-6 levels were significant after sensitivity analysis.
Jul 25, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Jul 26 ;884:173368. Epub 2020 Jul 26. PMID:
32726657
Article Published Date
: Jul 25, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The effects of pomegranate supplementation on biomarkers of inflammation and endothelial dysfunction.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2020 Mar ;49:102358. Epub 2020 Feb 26. PMID:
32147056
Article Published Date
: Feb 29, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Pomegranate
Diseases
:
Endothelial Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The present review provides the evidence of LLLT-dependent reduction of IL-1β, TNF-α, and MMP-13.
Aug 23, 2020
Click here to read the entire abstract
Pubmed Data
: Lasers Med Sci. 2020 Aug 24. Epub 2020 Aug 24. PMID:
32833088
Article Published Date
: Aug 23, 2020
Study Type
: Meta Analysis, Review
Additional Links
Diseases
:
Osteoarthritis
Therapeutic Actions
:
Laser Treatment: Low-Level
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
This meta-analysis showed the promising effect of melatonin administration on reducing CRP and IL-6 among patients with MetS and related disorders.
Jun 14, 2018
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2018 Jun 15. Epub 2018 Jun 15. PMID:
29907916
Article Published Date
: Jun 14, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Melatonin
Diseases
:
C-Reactive Protein
,
Metabolic Syndrome X
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
This suggests that CQ10 supplementation likely attenuates subclinical inflammation.
Aug 24, 2017
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 Aug 25. Epub 2017 Aug 25. PMID:
28847708
Article Published Date
: Aug 24, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
C-Reactive Protein
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Tomato products and lycopene supplementation have positive effects on blood lipids, blood pressure and endothelial function.
Jan 12, 2017
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2017 Jan 13 ;257:100-108. Epub 2017 Jan 13. PMID:
28129549
Article Published Date
: Jan 12, 2017
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Lycopene
,
Tomato
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Anticholesteremic Agents
,
Antihypertensive Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Risk Reduction
[+]
Vitamin C supplementation attenuates the oxidative stress and inflammatory response to a single bout of exercise.
Mar 10, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2020 Mar 11. Epub 2020 Mar 11. PMID:
32162041
Article Published Date
: Mar 10, 2020
Study Type
: Meta Analysis
Additional Links
Substances
:
Vitamin C
Diseases
:
Inflammation
,
Muscle Damage: Exercise-Induced
,
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
[+]
A combination of gastrodin, folate, and vitamin-B12 in addition to standard antiepileptic treatment can effectively control epileptic seizures.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Nov ;14(5):4801-4806. Epub 2017 Sep 14. PMID:
29201182
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Folate
,
Gastrodin
,
Vitamin B-12
Diseases
:
Epilepsy
,
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticonvulsants
,
Interleukin-2 Downregulation
,
Interleukin-6 Downregulation
[+]
A dietary mixture of sesame, pumpkin and flax seed added to a habitual diet lowered triglyceride and CRP, TNF-alpha, IL-6 levels
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ScientificWorldJournal. 2014 ;2014:563576. Epub 2014 Jan 22. PMID:
24578648
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
,
Pumpkin Seeds
,
Sesame Seeds
Diseases
:
Inflammation
,
Kidney Failure
Pharmacological Actions
:
Anti Inflammatory
,
Hypoglycemic Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Supplementation
[+]
A hydro alcoholic extract of nettle could decrease the levels of IL-6 and hs-CRP in patients with type 2 diabetes.
Jul 31, 2011
Click here to read the entire abstract
Pubmed Data
: Pak J Biol Sci. 2011 Aug 1 ;14(15):775-9. PMID:
22303583
Article Published Date
: Jul 31, 2011
Study Type
: Human Study
Additional Links
Substances
:
Nettle
Diseases
:
C-Reactive Protein
,
Diabetes Mellitus: Type 2
,
Inflammation
,
Insulin Resistance
Therapeutic Actions
:
Placebo Effect
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Plant Extracts
[+]
A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Drugs R D. 2008;9(4):243-50. PMID:
18588355
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endothelial Dysfunction
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Drug: Atorvastatin
,
Natural Substances Versus Drugs
,
Statin Alternatives
[+]
Active polymyalgia rheumatica is characterized by increased serum levels of Interleukin-6 probably originating in inflamed tissue.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: 1: Ann Rheum Dis. 2009 Mar 1. PMID:
19254903
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Polymyalgia Rheumatica
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Adherence to the mediterranean diet is inversely associated with inflammation (circulating interleukin-6) among middle-aged men.
Jan 15, 2008
Click here to read the entire abstract
Pubmed Data
: Circulation. 2008 Jan 15;117(2):169-75. Epub 2007 Dec 17. PMID:
18086924
Article Published Date
: Jan 15, 2008
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein
,
Cardiovascular Diseases
,
Inflammation
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Interleukin-6 Downregulation
Additional Keywords
:
Inverse Relationship
[+]
Aged garlic extract inhibits coronary artery calcification progression, lowers IL–6, glucose levels and blood pressure.
Apr 28, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Med Ther. 2020 Apr 29 ;20(1):132. Epub 2020 Apr 29. PMID:
32349742
Article Published Date
: Apr 28, 2020
Study Type
: Human Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antihypertensive Agents
,
Cardioprotective
,
Hypoglycemic Agents
,
Interleukin-6 Downregulation
[+]
Aged garlic extract may be beneficial in preventing the development of chronic diseases associated with low-grade inflammation.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Nutr ESPEN. 2018 04 ;24:148-155. Epub 2018 Jan 3. PMID:
29576354
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
C-Reactive Protein
,
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Immunomodulatory
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
An anthocyanin mixture reduced the inflammatory response in hypercholesterolemic subjects.
Aug 31, 2013
Click here to read the entire abstract
Pubmed Data
: Nutr Metab Cardiovasc Dis. 2013 Sep ;23(9):843-9. Epub 2012 Aug 17. PMID:
22906565
Article Published Date
: Aug 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Anthocyanins
,
Cyanidin 3-glucoside
,
Delphinidin
Diseases
:
Atherosclerosis
,
C-Reactive Protein
,
High Cholesterol
,
Hypercholesterolemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Dose Response
,
Natural Substance Synergy
[+]
An elemental diet reduces mucosal inflammation in patients with active Crohn's disease with remission occuring in 71% of patients.
Jun 01, 2005
Click here to read the entire abstract
Pubmed Data
: Inflamm Bowel Dis. 2005 Jun;11(6):580-8. PMID:
15905706
Article Published Date
: Jun 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
Therapeutic Actions
:
Dietary Modification: Elemental Diet
Pharmacological Actions
:
Interleukin-1 receptor antagonist
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Antioxidant activity of hydroxytyrosol and vitamin E reduces systemic inflammation in children with paediatric NAFLD.
Oct 11, 2020
Click here to read the entire abstract
Pubmed Data
: Dig Liver Dis. 2020 Oct 12. Epub 2020 Oct 12. PMID:
33060043
Article Published Date
: Oct 11, 2020
Study Type
: Human Study
Additional Links
Substances
:
Hydroxytyrosol
,
Vitamin E
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Association of endodontic infection with detection of an initial lesion to the cardiovascular system.
Nov 30, 2011
Click here to read the entire abstract
Pubmed Data
: J Endod. 2011 Dec ;37(12):1624-9. PMID:
22099894
Article Published Date
: Nov 30, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Periodontal Diseases
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astaxanthin addition improves human neutrophils function.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2010 Dec;49(8):447-57. Epub 2010 Apr 2. PMID:
20361333
Article Published Date
: Dec 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Immune Disorders: Low Immune Function
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Immunostimulatory
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Astragalus improves cardiac function in aged patients with Chronic Heart Failure.
Sep 01, 2005
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2005 Sep;11(3):187-90. PMID:
16181532
Article Published Date
: Sep 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Astragalus
Diseases
:
Heart Failure
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Beneficial effects of Lactobacillus plantarum on glycemia and homocysteine levels in postmenopausal women with metabolic syndrome.
Jun 30, 2014
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2014 Jul-Aug;30(7-8):939-42. Epub 2013 Dec 14. PMID:
24613434
Article Published Date
: Jun 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus plantarum
Diseases
:
Cardiovascular Diseases
,
Inflammation
,
Metabolic Syndrome X
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Minerva Med. 2018 Dec ;109(6):418-428. Epub 2018 Sep 13. PMID:
30221912
Article Published Date
: Nov 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Probiotics
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Hypolipidemic
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine possesses potential lipid-regulating, antiarthritis, and synovial hyperplasia inhibition activities against rheumatoid arthritis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:2580207. Epub 2019 Nov 3. PMID:
31781264
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Berberine
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypolipidemic
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Berberine promoted myocardial protection of postoperative patients through regulating myocardial autophagy.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Sep ;105:1050-1053. Epub 2018 Jun 19. PMID:
30021340
Article Published Date
: Aug 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Berberine
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Beta-glucan modulates waist circumference and inflammation in obese subjects.
Mar 04, 2017
Click here to read the entire abstract
Pubmed Data
: J Diet Suppl. 2017 Mar 4 ;14(2):173-185. Epub 2016 Aug 11. PMID:
27715351
Article Published Date
: Mar 04, 2017
Study Type
: Human Study
Additional Links
Substances
:
Beta-glucan
Diseases
:
Inflammation
,
Obesity
Pharmacological Actions
:
Hypotensive
,
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
[+]
Brief mindfulness training reduces salivary IL-6 and TNF-α in young women with depressive symptomatology.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Consult Clin Psychol. 2016 Oct ;84(10):887-97. Epub 2016 Jun 9. PMID:
27281371
Article Published Date
: Sep 30, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Depression
,
Inflammation
Therapeutic Actions
:
Meditation
,
Mindfullness Training
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Burdock root tea improves inflammatory status and oxidative stress in patients with knee osteoarthritis.
Oct 27, 2014
Click here to read the entire abstract
Pubmed Data
: Int J Rheum Dis. 2014 Oct 28. Epub 2014 Oct 28. PMID:
25350500
Article Published Date
: Oct 27, 2014
Study Type
: Human Study
Additional Links
Substances
:
Burdock
Diseases
:
C-Reactive Protein
,
Inflammation
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
[+]
Cardamonin is a potential candidate for controlling inflammation during primary Sjögren's syndrome.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2018 Apr ;40(2):126-133. Epub 2018 Jan 5. PMID:
29303022
Article Published Date
: Mar 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Cardamonin
Diseases
:
Inflammation
,
Sjogren's Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.
Dec 06, 2006
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2006 Dec 6;108(3):398-406. Epub 2006 Jun 2. PMID:
16824715
Article Published Date
: Dec 06, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chaihu Shihuang soup can significantly regulate cytokine and improve early recovery of severe acute pancratitis.
May 31, 2009
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2009 Jun ;34(12):1582-4. PMID:
19777852
Article Published Date
: May 31, 2009
Study Type
: Human Study
Additional Links
Substances
:
Soup
Diseases
:
Pancreatitis
Pharmacological Actions
:
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Significant Treatment Outcome
[+]
Children and adolescents with ADHD who received Lactobacillus rhamnosus GG supplementation reported better health-related quality of life.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Psychiatry. 2020 ;11:181. Epub 2020 Mar 17. PMID:
32256407
Article Published Date
: Dec 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus rhamnosus GG
Diseases
:
Attention Deficit Disorder with Hyperactivity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Chronic ingestion of acrylamide-containing products (potato chips) induces a proinflammatory state, a risk factor for progression of atherosclerosis.
Mar 01, 2009
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2009 Mar ;89(3):773-7. Epub 2009 Jan 21. PMID:
19158207
Article Published Date
: Mar 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein
,
Cholesterol: Oxidation
,
Lipid Peroxidation
Pharmacological Actions
:
Interleukin-6 Downregulation
Problem Substances
:
Acrylamide
,
Potato
,
Potato Chips
Adverse Pharmacological Actions
:
Atherogenic
,
Inflammatory
[+]
Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime.
Jul 01, 2002
Click here to read the entire abstract
Pubmed Data
: Metabolism. 2002 Jul;51(7):887-92. PMID:
12077736
Article Published Date
: Jul 01, 2002
Study Type
: Human Study
Additional Links
Diseases
:
Insomnia
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Coenzyme Q10 might have a role as a good supplement in young children with Down syndrome to ameliorate the neurological symptoms.
Oct 18, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pediatr (Rio J). 2016 Oct 19. Epub 2016 Oct 19. PMID:
27770619
Article Published Date
: Oct 18, 2016
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Down Syndrome
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Coenzyme Q10 supplementation could be effective in ameliorating inflammatory cytokine levels caused by breast cancer.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ther Clin Risk Manag. 2019 ;15:1403-1410. Epub 2019 Dec 4. PMID:
31824163
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
[+]
Combined therapy regulates the inflammatory process and oxidative stress and contributes to immune protection on patients with T2D.
May 07, 2018
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2018 May 8 ;24:2887-2900. Epub 2018 May 8. PMID:
29735963
Article Published Date
: May 07, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Diabetes Mellitus: Type 2
,
Diabetic Complications
Therapeutic Actions
:
Acupuncture
,
Hydrotherapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Consumption of black currant nectar prior to and after a bout of eccentric exercise attenuates muscle damage and inflammation.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Diet Suppl. 2016 ;13(1):1-15. Epub 2014 Aug 25. PMID:
25153307
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Black Currant
Diseases
:
Inflammation
,
Muscle Damage: Exercise-Induced
,
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Consumption of cruciferous and apiaceous vegetables reduced circulating IL-6.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2014 Nov ;144(11):1850-7. Epub 2014 Aug 27. PMID:
25165394
Article Published Date
: Oct 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Cruciferous Vegetables
,
Isothiocyanate
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Consumption of pomegranate peel extract in combination with vitamin E enhanced the inflammatory status and endothelial function in hemodialysis patients.
Aug 24, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 Aug 25. Epub 2020 Aug 25. PMID:
32839797
Article Published Date
: Aug 24, 2020
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate Peel
,
Vitamin E
Diseases
:
Endothelial Dysfunction
,
Hemodialysis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
CoQ10 supplementation at a dosage of 500 mg appears to decrease inflammatory markers in patients with MS.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2015 May ;18(4):169-76. Epub 2014 Jan 10. PMID:
24621064
Article Published Date
: Apr 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin and Boswellia serrata are safe and tolerable and helped to improvethe levels of an inflammatory cytokine (IL-6).
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: J Complement Integr Med. 2013 ;10(1):1-10. Epub 2013 Jul 1. PMID:
23828329
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Boswellia
,
Turmeric
Diseases
:
Chronic Kidney Disease (CKD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Substance Combination
[+]
Curcumin supplementation effectively mitigates inflammation in patients suffering from chronic SM-induced cutaneous complications.
Oct 31, 2012
Click here to read the entire abstract
Pubmed Data
: Ann Clin Biochem. 2012 Nov ;49(Pt 6):580-8. Epub 2012 Oct 4. PMID:
23038702
Article Published Date
: Oct 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemical Weapon Agent Injury: Sulfur Mustard
Pharmacological Actions
:
Interleukin-6 Downregulation
Problem Substances
:
Mustard Gas
[+]
Curcumin supplementation significantly decreases serum concentrations of pro-inflammatory cytokines in subjects with MetS.
Jun 05, 2016
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2016 Jun 6 ;82:578-582. Epub 2016 Jun 6. PMID:
27470399
Article Published Date
: Jun 05, 2016
Study Type
: Human Study
Additional Links
Substances
:
Curcumin
Diseases
:
Metabolic Diseases
,
Metabolic Syndrome X
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID:
25948780
Article Published Date
: Jun 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Bacillus coagulans
Diseases
:
C-Reactive Protein
,
Dysbiosis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Gastrointestinal Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Microbiota
[+]
Daily supplementation of coenzyme Q10 can be effective in decreasing some pro-inflammatory factors in hypertensive patients.
Nov 30, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2015 Dec ;85(3-4):156-164. PMID:
26780394
Article Published Date
: Nov 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
C-Reactive Protein
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Dark chocolate has beneficial effects on serum adiponectin, biochemical and inflammatory parameters in diabetic patients.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Prev Med. 2018 ;9:86. Epub 2018 Oct 12. PMID:
30450169
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Chocolate
Diseases
:
C-Reactive Protein
,
Diabetes Mellitus: Type 2
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Defatted flaxseed flour improves weight loss and lipid profile in overweight and obese adults.
Sep 22, 2020
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2020 Sep 23 ;11(9):8237-8247. PMID:
32966475
Article Published Date
: Sep 22, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypolipidemic
,
Interleukin-6 Downregulation
Additional Keywords
:
Anti-Obesity Agents
[+]
Dietary soy improves the inflammatory and nutritional status in end-stage renal disease patients on chronic hemodialysis
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: Nephrol Dial Transplant. 2006 Aug;21(8):2239-46. Epub 2006 Jun 9. PMID:
16766544
Article Published Date
: Aug 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones
Diseases
:
C-Reactive Protein
,
Hemodialysis
,
Inflammation
,
Kidney Failure
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary strawberries may have significant analgesic and anti-inflammatory effects in obese adults with established knee osteoarthritis.
Aug 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Aug 28 ;9(9). Epub 2017 Aug 28. PMID:
28846633
Article Published Date
: Aug 27, 2017
Study Type
: Human Study
Additional Links
Substances
:
Strawberry
Diseases
:
Osteoarthritis: Knee
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords
:
Analgesics
,
Anti-Inflammatory Agents
,
Osteoarthritis: Knee
,
Strawberry
[+]
Dietary supplementation with pressurized whey may potentiate the effects of exercise training on exercise tolerance and quality of life in patients with COPD.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2010 Jun;13(3):589-98. PMID:
20521985
Article Published Date
: Jun 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Whey
Diseases
:
Athletic Performance
,
C-Reactive Protein
,
COPD
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Effect of diosmin administration in patients with chronic venous disorders on selected factors affecting angiogenesis.
Sep 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Sep 12 ;24(18). Epub 2019 Sep 12. PMID:
31547271
Article Published Date
: Sep 11, 2019
Study Type
: Human Study
Additional Links
Substances
:
Diosmin
Diseases
:
Chronic Venous Insufficency
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
,
Vascular Endothelial Growth Factor C Inhibitor
[+]
Effect of yoga therapy on disease activity, inflammatory markers, and heart rate variability in patients with rheumatoid arthritis.
Apr 22, 2020
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2020 Apr 23. Epub 2020 Apr 23. PMID:
32326727
Article Published Date
: Apr 22, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Rheumatoid Arthritis
Therapeutic Actions
:
Yoga
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 alpha downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
EGCG and coconut oil improve state anxiety and functional capacity in patients with multiple sclerosis.
Jan 22, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2020 Jan 23 ;12(2). Epub 2020 Jan 23. PMID:
31979305
Article Published Date
: Jan 22, 2020
Study Type
: Human Study
Additional Links
Substances
:
Coconut Oil
,
EGCG (Epigallocatechin gallate)
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Either free radicals are not involved in delaying the recovery process following a bout of unaccustomed exercise or the consumption of VitaminC wholly after exercise is unable to deliver this antioxidant to the appropriate sites with sufficient expediency
Apr 30, 2003
Click here to read the entire abstract
Pubmed Data
: Eur J Appl Physiol. 2003 May ;89(3-4):393-400. Epub 2003 Apr 1. PMID:
12682838
Article Published Date
: Apr 30, 2003
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
Additional Keywords
:
Prolonged Exercise
,
Recovery
,
Vitamin C Supplementation
Anti Therapeutic Actions
:
Oxidative Damage
[+]
Electroacupuncture can effectively decrease the proinflammatory cytokine of IL-1 and IL-6 and increase the inhibition cytokine of IL-4 and IL-10 and improve the internal environment of occurrence and progression of rheumatoid arthritis.
Oct 01, 2010
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhen Jiu. 2010 Oct;30(10):840-4. PMID:
21058483
Article Published Date
: Oct 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Rheumatoid Arthritis
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Interleukin-10 downregulation
,
Interleukin-4 downregulation
,
Interleukin-6 Downregulation
[+]
Electrolyzed reduced water (i.e. structured water) reduces hemodialysis-induced oxidative stress in end-stage kidney disease patients.
Aug 01, 2003
Click here to read the entire abstract
Pubmed Data
: Kidney Int. 2003 Aug;64(2):704-14. PMID:
12846769
Article Published Date
: Aug 01, 2003
Study Type
: Human Study
Additional Links
Substances
:
Water: Electrolyzed Reduced
Diseases
:
Hemodialysis
,
Kidney Failure
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
[+]
Exercise decreases C-reactive protein with with increased exercise time.
Nov 23, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2015 Nov 24. Epub 2015 Nov 24. PMID:
26603740
Article Published Date
: Nov 23, 2015
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein
,
Inflammation
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Flaxseed and flaxseed oil attenuate inflammatory markers, disease severity, blood pressure in patients with ulcerative colitis.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Complement Ther Med. 2019 Oct ;46:36-43. Epub 2019 Jul 19. PMID:
31519285
Article Published Date
: Sep 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed Oil
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antihypertensive Agents
,
Interferon Gamma Reducer
,
Interleukin-6 Downregulation
[+]
Folic acid supplementation mitigates Alzheimer's disease by reducing inflammation.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2016 ;2016:5912146. Epub 2016 Jun 2. PMID:
27340344
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Folic Acid
,
Vitamin B-12
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Forest bathing has therapeutic effects on human hypertension and induces inhibition of the renin–angiotensin system and inflammation.
Nov 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cardiol. 2012 Dec ;60(6):495-502. Epub 2012 Sep 1. PMID:
22948092
Article Published Date
: Nov 30, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Cardiovascular Diseases
,
Hypertension
,
Inflammation
Therapeutic Actions
:
Shinrin-yoku (taking in the atmosphere of the forest)
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Forest bathing is beneficial to human health.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Biomed Environ Sci. 2012 Jun ;25(3):317-24. PMID:
22840583
Article Published Date
: May 31, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Cortisol: High
,
Oxidative Stress
Therapeutic Actions
:
Shinrin-yoku (taking in the atmosphere of the forest)
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Frequent nut consumption was associated with a healthy profile of inflammatory biomarkers.
Jul 26, 2016
Click here to read the entire abstract
Pubmed Data
: Am J Clin Nutr. 2016 Jul 27. Epub 2016 Jul 27. PMID:
27465378
Article Published Date
: Jul 26, 2016
Study Type
: Human Study
Additional Links
Substances
:
Nuts
Diseases
:
C-Reactive Protein
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Risk Reduction
[+]
Garlic extract had beneficial effects on serum inflammatory markers of peritoneal dialysis patients.
Jan 24, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Nephrol. 2019 Jan 25 ;20(1):26. Epub 2019 Jan 25. PMID:
30683061
Article Published Date
: Jan 24, 2019
Study Type
: Human Study
Additional Links
Substances
:
Garlic
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Genistein can reduce insulin resistance, oxidative and inflammatory indices along with improvement in fat metabolism in patients with NAFLD.
May 31, 2017
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2017 Jun 1. Epub 2017 Jun 1. PMID:
28647291
Article Published Date
: May 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Genistein
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Anti-Inflammatory Agents
,
Antioxidants
,
Genistein
,
Nonalcoholic fatty liver disease (NAFLD)
[+]
Ginkgo is effective in treating pulmonary interstitial fibrosis.
Mar 01, 2005
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 Mar;25(3):222-4. PMID:
15842142
Article Published Date
: Mar 01, 2005
Study Type
: Human Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Interstitial Lung Diseases
,
Pulmonary Fibrosis
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Honey reduce the probable aggravating effects of intensive cycling training on spermatogenesis and fertility capacity in road cyclists.
Apr 30, 2012
Click here to read the entire abstract
Pubmed Data
: J Androl. 2012 May-Jun;33(3):449-61. Epub 2011 Jun 2. PMID:
21636735
Article Published Date
: Apr 30, 2012
Study Type
: Human Study
Additional Links
Substances
:
Honey
Diseases
:
Exercise-Induced Hormone Fluctuations
,
Infertility: Male
,
Oxidative Stress
Therapeutic Actions
:
Exercise: Cycling
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Horticultural therapy by reducing plasma IL-6 may prevent inflammatory disorders.
Aug 08, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2018 Aug 9 ;15(8). Epub 2018 Aug 9. PMID:
30096932
Article Published Date
: Aug 08, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
Therapeutic Actions
:
Horticultural Therapy (Gardening)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
IL-6 levels significantly decreased with 70 days of broccoli consumption.
Mar 12, 2018
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2018 Mar 13. Epub 2018 Mar 13. PMID:
29573889
Article Published Date
: Mar 12, 2018
Study Type
: Human Study
Additional Links
Substances
:
Broccoli Sprouts
Diseases
:
Obesity
,
Overweight
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Impact of resveratrol supplementation on inflammatory, antioxidant, and periodontal markers in type 2 diabetic patients with chronic periodontitis.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Diabetes Metab Syndr. 2019 Jul - Aug;13(4):2769-2774. Epub 2019 Jul 24. PMID:
31405706
Article Published Date
: Jul 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Diabetes Mellitus: Type 2
,
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
[+]
In patients with stable coronary artery disease, an independent and inverse association exists between n-3 fatty acid levels and inflammatory biomarkers.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2009 Aug;205(2):538-43. Epub 2008 Dec 14. PMID:
19185299
Article Published Date
: Aug 01, 2009
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
C-Reactive Protein
,
Coronary Artery Disease
,
Inflammation
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Including almonds in diets as a snack may help healthy overweight and obese individuals improve nutritional status and reduce their risk for CVD.
Jul 09, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Nutr. 2017 Jul 10. Epub 2017 Jul 10. PMID:
28695324
Article Published Date
: Jul 09, 2017
Study Type
: Human Study
Additional Links
Substances
:
Almond
,
Vitamin E
Diseases
:
Cardiovascular Disease: Prevention
,
Obesity
,
Overweight
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Risk Reduction
[+]
Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2008 Apr ;138(4):732-9. PMID:
18356328
Article Published Date
: Apr 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Fiber
Diseases
:
Adiponectin: Low Levels
,
Inflammation
,
Insulin Resistance
Pharmacological Actions
:
Adiponectin upregulation
,
Interleukin-6 Downregulation
Problem Substances
:
Insulin
[+]
Inclusion of dried grapes in diet was beneficial in NAFLD patients with non-significant fibrosis.
Nov 08, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Nov 9 ;7(11):4533-4544. PMID:
27714002
Article Published Date
: Nov 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
Raisins
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypoglycemic Agents
,
Interleukin-6 Downregulation
[+]
Increased production of Interleukin-6 is a characteristic of patients with polymyalgia rheumatica and giant cell arteritis.
Sep 01, 1993
Click here to read the entire abstract
Pubmed Data
: Arthritis Rheum. 1993 Sep;36(9):1286-94. PMID:
8216422
Article Published Date
: Sep 01, 1993
Study Type
: Human Study
Additional Links
Diseases
:
Giant Cell Arteritis
,
Polymyalgia Rheumatica
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Increasing tomato intake may provide a useful approach for reducing the risk of inflammatory diseases such as CVD and diabetes, which are associated with obesity.
May 31, 2013
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2013 Jun ;109(11):2031-5. Epub 2012 Oct 15. PMID:
23069270
Article Published Date
: May 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Lycopene
,
Tomato
Diseases
:
Inflammation
,
Obesity
,
Overweight
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Risk Reduction
[+]
Inflammation may link obesity with asthma.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Clin Invest Med. 2008;31(6):E373-9. Epub 2008 Dec 1. PMID:
19032908
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Asthma
,
C-Reactive Protein
,
Inflammation
,
Obesity
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Obesity-Asthma-Inflammation Link
[+]
Intake of bilberries has an ameliorating effect on some markers of gingival inflammation reducing gingivitis to a similar extent compared to standard of care.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2015 ;16(5):10665-73. Epub 2015 May 11. PMID:
25970751
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Bilberry
Diseases
:
Gingivitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Intrathecal CAPE following spinal cord injury decreases tissue and serum IL-6 levels as well as decreases spinal cord edema and microhemorrhage.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Turk Neurosurg. 2018 ;28(4):625-629. PMID:
30192364
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Irritable eye syndrome: neuroimmune mechanisms and benefits of selected nutrients.
Mar 31, 2014
Click here to read the entire abstract
Pubmed Data
: Ocul Surf. 2014 Apr ;12(2):134-45. Epub 2013 Dec 30. PMID:
24725325
Article Published Date
: Mar 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Vitamin A
,
Vitamin D
Diseases
:
Eye Diseases
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
L. plantarum PS128 may be a potential ergogenic aid for better training management, physiological adaptations to exercise, and health promotion.
Feb 06, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 Feb 7 ;11(2). Epub 2019 Feb 7. PMID:
30736479
Article Published Date
: Feb 06, 2019
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus plantarum
Diseases
:
Athletic Performance
,
Inflammation
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Lactobacillus acidophilus modulates inflammatory activity by regulating the TLR4 and NF-κB expression in porcine peripheral blood mononuclear cells.
Feb 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2016 Feb 28 ;115(4):567-75. Epub 2016 Jan 15. PMID:
26769562
Article Published Date
: Feb 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus Acidophilus
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Interferon Gamma Reducer
,
Interleukin-10 upregulation
,
Interleukin-4 upregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Lipoic acid down-regulates inflammation in multiple sclerosis patients.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2010;5(9). Epub 2010 Sep 28. PMID:
20927401
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Brain Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
cAMP up-regulation
,
Interleukin-17 downregulation
,
Interleukin-6 Downregulation
[+]
Local ice cryotherapy had beneficial effects in human non-septic knee arthritis.
Jul 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Arthritis Res Ther. 2019 Jul 30 ;21(1):180. Epub 2019 Jul 30. PMID:
31362785
Article Published Date
: Jul 29, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Arthritis
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Postaglandin PGE2 downregulation
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Long-term bicycle riding improves the quality of life and reduces the severity of depression in patients suffering from chronic hemodialysis.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neuropsychiatr Dis Treat. 2017 ;13:91-100. Epub 2016 Dec 28. PMID:
28096677
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Hemodialysis
Therapeutic Actions
:
Exercise: Cycling
Pharmacological Actions
:
Antidepressive Agents
,
Interleukin-18 down-regulation
,
Interleukin-6 Downregulation
[+]
Low dietary intake of beta-carotene, alpha-tocopherol and ascorbic acid is associated with increased inflammatory and oxidative stress status.
May 31, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Nutr. 2009 Jun ;101(12):1775-82. Epub 2008 Dec 15. PMID:
19079838
Article Published Date
: May 31, 2009
Study Type
: Human Study
Additional Links
Substances
:
beta-Carotene
,
Vitamin C
,
Vitamin E: alpha tocopherol
Diseases
:
C-Reactive Protein
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
[+]
Low-level laser therapy may be useful to improve the symptoms of chemotherapy-induced oral mucositis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Lasers Med Sci. 2019 ;10(2):125-130. Epub 2019 Feb 25. PMID:
31360381
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy and Radiation Toxicity
,
Oral Mucositis
Therapeutic Actions
:
Laser Treatment: Low-Level
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Lutein exerts anti-inflammatory effects in patients with coronary artery disease.
May 05, 2017
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2017 May 6 ;262:87-93. Epub 2017 May 6. PMID:
28527371
Article Published Date
: May 05, 2017
Study Type
: Human Study
Additional Links
Substances
:
Lutein
Diseases
:
Coronary Artery Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
Additional Keywords
:
Dose Response
[+]
Mastic gum has significant therapeutic value in patients with mildly to moderately active Crohns disease.
Feb 07, 2007
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2007 Feb 7;13(5):748-53. PMID:
17278198
Article Published Date
: Feb 07, 2007
Study Type
: Human Study
Additional Links
Substances
:
Mastic gum
Diseases
:
Crohn's Disease
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Melatonin can modulate the inflammatory actions in periodontal patients.
Nov 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Exp Dent. 2015 Dec ;7(5):e628-e633. Epub 2015 Dec 1. PMID:
26644840
Article Published Date
: Nov 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Melatonin
Diseases
:
C-Reactive Protein
,
Inflammation
,
Periodontal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Mindfulness and pharmacological prophylaxis have comparable effect on biomarkers of inflammation and clinical indexes in chronic migraine.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Neurol Sci. 2017 May ;38(Suppl 1):173-175. PMID:
28527073
Article Published Date
: Apr 30, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Headache: Migraine
,
Inflammation
Therapeutic Actions
:
Meditation
,
Mindfullness Training
Pharmacological Actions
:
Analgesics
,
Interleukin-6 Downregulation
Problem Substances
:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]
Mindfulness meditation training is associated with improvements in a marker of inflammatory disease risk.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Biol Psychiatry. 2016 Jul 1 ;80(1):53-61. Epub 2016 Jan 29. PMID:
27021514
Article Published Date
: Jun 30, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
Therapeutic Actions
:
Mindfullness Training
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Risk Reduction
[+]
Mindfulness practice predicts interleukin-6 responses to a mindfulness-based alcohol relapse prevention intervention.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Subst Abuse Treat. 2019 Oct ;105:57-63. Epub 2019 Aug 1. PMID:
31443893
Article Published Date
: Sep 30, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Alcohol Addiction
,
Alcohol Withdrawal
Therapeutic Actions
:
Mindfullness Training
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Mindfulness-based stress reduction to enhance psychological functioning and improve inflammatory biomarkers in trauma-exposed women.
Oct 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Psychol Trauma. 2015 Nov ;7(6):525-32. Epub 2015 Apr 27. PMID:
25915646
Article Published Date
: Oct 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Stress Disorders: Post-Traumatic
Therapeutic Actions
:
Meditation
,
Mindfullness Training
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Montmorency cherries significantly lowered systemic inflammatory and oxidative stress induced by a series of metabolically challenging cycling bouts.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2014 ;6(2):829-43. Epub 2014 Feb 21. PMID:
24566440
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Tart Cherry
Diseases
:
C-Reactive Protein
,
Inflammation
,
Muscle Damage: Exercise-Induced
,
Oxidative Stress
Pharmacological Actions
:
Anti Inflammatory
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Music alters constitutively expressed opiate and cytokine processes in listeners, resulting in physiological changes such as reduced blood pressure.
Jun 01, 2004
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2004 Jun;10(6):MS18-27. Epub 2004 Jun 1. PMID:
15173680
Article Published Date
: Jun 01, 2004
Study Type
: Human Study
Additional Links
Diseases
:
Hypertension
,
Stress
Therapeutic Actions
:
Music
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Music therapy decreased congestive heart failure in elderly patients by reducing plasma cytokine and catecholamine levels.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Int Heart J. 2009 Jan;50(1):95-110. PMID:
19246850
Article Published Date
: Jan 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Congestive Heart Failure
,
Elderly: Age Specific Diseases
,
Heart Failure
Therapeutic Actions
:
Music
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
N-Acetylcysteine protects human bronchi by modulating the release of neurokinin A in an ex vivo model of COPD exacerbation.
Jun 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2018 Jul ;103:1-8. Epub 2018 Apr 24. PMID:
29635121
Article Published Date
: Jun 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Chronic Obstructive Pulmonary Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Nigella sativa oil mouth rinse improves chemotherapy-induced oral mucositis in patients with acute myeloid leukemia.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2019 ;2019:3619357. Epub 2019 Oct 30. PMID:
31781612
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acute Myeloid Leukemia
,
Radiation Induced Illness: Mucositis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Radioprotective
[+]
Nigella sativa seed oil supplements may decrease the liver enzymes and lipid profiles in the patients with NAFLD.
Nov 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Diabetes Metab Disord. 2019 Dec ;18(2):453-459. Epub 2019 Sep 11. PMID:
31890671
Article Published Date
: Nov 30, 2019
Study Type
: Human Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
,
Thymoquinone
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Nondiabetic patients with stage 3-4 CKD and vitamin D deficiency, vitamin D supplementation may improve vascular function.
Sep 30, 2017
Click here to read the entire abstract
Pubmed Data
: J Am Soc Nephrol. 2017 Oct ;28(10):3100-3108. Epub 2017 Jun 30. PMID:
28667080
Article Published Date
: Sep 30, 2017
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Chronic Kidney Disease (CKD)
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Vasoprotective
[+]
Oat porridge consumption alleviates markers of inflammation and oxidative stress in hypercholesterolemic adults.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asia Pac J Clin Nutr. 2019 ;28(2):260-265. PMID:
31192555
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Porridge
Diseases
:
Hypercholesterolemia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Olive fruit and almond skin extract seems to protect LDL from oxidation and to prevent inflammatory status in moderately hypercholesterolemic subjects.
Aug 17, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2020 Aug 18. Epub 2020 Aug 18. PMID:
32816626
Article Published Date
: Aug 17, 2020
Study Type
: Human Study
Additional Links
Substances
:
Almond
,
Olive
Diseases
:
Hypercholesterolemia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Olive oil consumption has an ameliorative effect in non-alcoholic fatty liver disease.
Apr 21, 2009
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2009 Apr 21;15(15):1809-15. PMID:
19370776
Article Published Date
: Apr 21, 2009
Study Type
: Human Study
Additional Links
Substances
:
Olive Oil
Diseases
:
Fatty Liver
,
Insulin Resistance
Therapeutic Actions
:
Dietary Modification: Mediterranean Diet
Pharmacological Actions
:
Antioxidants
,
Glucagon Like peptide 1 (GLP-1) Up-regulation
,
Glucose transporter-2 (GLUT2) expression up-regulation
,
Insulin Sensitizers
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
[+]
Omega-3 fatty acids decrease oxidative stress and inflammation in macrophages from patients with small abdominal aortic aneurysm
Sep 09, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2019 Sep 10 ;9(1):12978. Epub 2019 Sep 10. PMID:
31506475
Article Published Date
: Sep 09, 2019
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Omega-3 long chain-polyunsaturated fatty acids could have a potential therapeutic impact on chronic inflammation in Duchenne muscular dystrophy.
Sep 22, 2017
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2017 Sep 23. Epub 2017 Sep 23. PMID:
28987470
Article Published Date
: Sep 22, 2017
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
Diseases
:
Duchenne's Muscular Dystrophy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
One week of magnesium supplementation lowers IL-6, muscle soreness and increases post-exercise blood glucose in response to downhill running.
Oct 16, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Appl Physiol. 2019 Oct 17. Epub 2019 Oct 17. PMID:
31624951
Article Published Date
: Oct 16, 2019
Study Type
: Human Study
Additional Links
Substances
:
Magnesium
Diseases
:
Muscle Soreness
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Oral cryotherapy was effective for reducing oral mucositis, reactive oxygen series, and inflammatory cytokines in patients undergoing chemotherapy.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Korean Acad Nurs. 2019 Apr ;49(2):149-160. PMID:
31064968
Article Published Date
: Mar 31, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Chemotherapy and Radiation Toxicity
,
Oral Mucositis
Therapeutic Actions
:
Cryotherapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oral supplementation with omega-3 fatty acids and inflammation markers in patients with chronic kidney disease in hemodialysis.
Jan 13, 2020
Click here to read the entire abstract
Pubmed Data
: Appl Physiol Nutr Metab. 2020 Jan 14. Epub 2020 Jan 14. PMID:
31935118
Article Published Date
: Jan 13, 2020
Study Type
: Human Study
Additional Links
Substances
:
Omega-3 Fatty Acids
Diseases
:
Coronary Artery Disease
,
Hemodialysis
,
Kidney Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oral supplementation with probiotics could be helpful in maintaining remission and preventing relapse of ulcerative colitis.
Sep 06, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2010 Sep 7 ;16(33):4145-51. PMID:
20806430
Article Published Date
: Sep 06, 2010
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus delbrueckii Subsp
,
Lactobacillus fermentum
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Perioperative probiotic treatment prevents postoperative infectious complications in biliary cancer surgery.
Nov 01, 2006
Click here to read the entire abstract
Pubmed Data
: Ann Surg. 2006 Nov;244(5):706-14. PMID:
17060763
Article Published Date
: Nov 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Lactobacillus casei
,
Lactobacillus probiotics
,
Probiotics
Diseases
:
Biliary Obstruction
,
Biliary Tract Diseases
,
Liver Cancer
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Phototherapy can be an important tool in the obesity, mostly considering its potential effects associated to exercise training in attenuating inflammation in women.
May 09, 2015
Click here to read the entire abstract
Pubmed Data
: Lasers Med Sci. 2015 May 10. Epub 2015 May 10. PMID:
25958170
Article Published Date
: May 09, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
,
Obesity
Therapeutic Actions
:
Exercise
,
Light Therapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Risk Reduction
[+]
Pomegranate juice improves the cardiometabolic risk factors, biomarkers of oxidative stress and inflammation in hemodialysis patients.
Oct 22, 2019
Click here to read the entire abstract
Pubmed Data
: J Sci Food Agric. 2019 Oct 23. Epub 2019 Oct 23. PMID:
31646650
Article Published Date
: Oct 22, 2019
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hemodialysis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
[+]
PQQ supplementation enhanced mitochondria related functions.
Nov 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Nutr Biochem. 2013 Dec ;24(12):2076-84. PMID:
24231099
Article Published Date
: Nov 30, 2013
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein
,
Inflammation
Pharmacological Actions
:
Anti Inflammatory
,
Antioxidants
,
Interleukin-6 Downregulation
Additional Keywords
:
Diet
,
Mitochondrial Metabolism
[+]
Prebiotic-resistant starch supplementation seems to be a promising nutritional strategy to improve inflammation, oxidative stress and to reduce indoxyl sulfate plasma levels in chronic kidney disease patients on hemodialysis.
Dec 13, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 Dec 13 ;9(12):6508-6516. PMID:
30468238
Article Published Date
: Dec 13, 2018
Study Type
: Human Study
Additional Links
Substances
:
Resistant Starch
Diseases
:
C-Reactive Protein
,
Chronic Kidney Disease (CKD)
,
Hemodialysis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidant Effects
,
Interleukin-6 Downregulation
[+]
Probiotics yogurts suppress Helicobacter pylori load and modify immune response and intestinal microbiota in the Helicobacter pylori-infected children.
Jul 31, 2012
Click here to read the entire abstract
Pubmed Data
: Helicobacter. 2012 Aug ;17(4):297-304. Epub 2012 Mar 20. PMID:
22759330
Article Published Date
: Jul 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Probiotics
,
Yoghurt
Diseases
:
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Puerarin effectively improves clinical symptoms and vascular endothelial function and reduces the levels of inflammatory factors in patients with CAD.
Jan 13, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci Monit. 2019 Jan 14 ;25:402-408. Epub 2019 Jan 14. PMID:
30636768
Article Published Date
: Jan 13, 2019
Study Type
: Human Study
Additional Links
Substances
:
Puerarin
Diseases
:
Coronary Artery Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Recurrent aphthous stomatitis outbreaks are associated with low immune function.
Oct 01, 2007
Click here to read the entire abstract
Pubmed Data
: Georgian Med News. 2007 Oct(151):37-9. PMID:
18071210
Article Published Date
: Oct 01, 2007
Study Type
: Human Study
Additional Links
Diseases
:
Aphthous Ulcer
,
Immune Disorders: Low Immune Function
Pharmacological Actions
:
Interleukin-6 Downregulation
Additional Keywords
:
Diseases that are Linked
[+]
Regular practice of yoga can protect the individual against inflammatory diseases by favourably altering pro-inflammatory cytokine levels.
May 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Diagn Res. 2015 Jun ;9(6):CC08-12. Epub 2015 Jun 1. PMID:
26266115
Article Published Date
: May 31, 2015
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
Therapeutic Actions
:
Exercise
,
Yoga
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Regular practice of yogasanas improved glycaemic control, oxidative stress, inflammatory response and sleep quality among subjects with type 2 diabetes.
Dec 24, 2020
Click here to read the entire abstract
Pubmed Data
: Diabetes Res Clin Pract. 2020 Dec 25 ;172:108644. Epub 2020 Dec 25. PMID:
33359750
Article Published Date
: Dec 24, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Diabetes Mellitus: Type 2
Therapeutic Actions
:
Yoga
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoglycemic Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Salvia miltiorrhiza mitigates severe acute pancreatitis.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Zhong Xi Yi Jie He Xue Bao. 2007 Jan;5(1):28-31. PMID:
17214932
Article Published Date
: Jan 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Red Sage
Diseases
:
Pancreatitis
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Sesame seed is a natural and safe substance that may have beneficial effects in patients with knee osteoarthritis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Med Iran. 2015 ;53(4):207-13. PMID:
25871017
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Sesame Seeds
Diseases
:
C-Reactive Protein
,
Inflammation
,
Osteoarthritis: Knee
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
[+]
Sesamin can relieve clinical symptoms and pathological changes that caused by inflammatory impairment in patients with rheumatoid arthritis.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Sep ;33(9):2421-2428. Epub 2019 Jul 15. PMID:
31309643
Article Published Date
: Aug 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Sesamin
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Sesamin supplementation may be considered as a supplementary therapeutic approach for diabetic patients.
Jul 21, 2016
Click here to read the entire abstract
Pubmed Data
: J Diet Suppl. 2016 Jul 22:1-12. Epub 2016 Jul 22. PMID:
27450646
Article Published Date
: Jul 21, 2016
Study Type
: Human Study
Additional Links
Substances
:
Sesamin
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Adiponectin upregulation
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Silibinin may improve the effects of methotrexate on certain biochemical and clinical markers of patients with active rheumatoid arthritis.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oman Med J. 2016 Jul ;31(4):263-9. PMID:
27403238
Article Published Date
: Jun 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
C-Reactive Protein
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Soy supplementation reduced total and subcutaneous abdominal fat in postmenopausal women.
Mar 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2006 Spring;9(1):84-9. PMID:
20435291
Article Published Date
: Mar 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Soy Protein
Diseases
:
Obesity
,
Overweight
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Spirulina has favorable effects on lipid profiles, immune variables and antioxidant capacity in healthy individuals.
Jan 01, 2008
Click here to read the entire abstract
Pubmed Data
: Ann Nutr Metab. 2008;52(4):322-8. Epub 2008 Aug 19. PMID:
18714150
Article Published Date
: Jan 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Spirulina
Diseases
:
High Cholesterol
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-2 upregulation
,
Interleukin-6 Downregulation
[+]
Strawberries have a role in glycemic control and attenuating the pro-inflammatory effect of a modern diet.
Dec 06, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Dec 7 ;7(12):4745-4752. PMID:
27761543
Article Published Date
: Dec 06, 2016
Study Type
: Human Study
Additional Links
Substances
:
Strawberry
Diseases
:
Insulin Resistance
,
Overweight
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypoglycemic Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Risk Reduction
[+]
Successful therapy of Clostridium difficile infection with fecal microbiota transplantation.
Nov 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Physiol Pharmacol. 2016 Dec ;67(6):859-866. PMID:
28195066
Article Published Date
: Nov 30, 2016
Study Type
: Human Study
Additional Links
Diseases
:
C-Reactive Protein
,
Clostridium Infections
,
Diarrhea
,
Inflammation
Therapeutic Actions
:
Microbiota Transfer Therapy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-12 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The beneficial effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome.
Jan 23, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr J. 2020 Jan 24 ;19(1):8. Epub 2020 Jan 24. PMID:
31980022
Article Published Date
: Jan 23, 2020
Study Type
: Human Study
Additional Links
Substances
:
Flaxseed
Diseases
:
Polycystic Ovary Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Insulin Sensitizers
,
Interleukin-6 Downregulation
[+]
The combined application of berberine in patients with metabolic syndrome can effectively regulate blood glucose and blood lipid of patients.
Mar 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 Apr ;17(4):3009-3014. Epub 2019 Feb 22. PMID:
30936971
Article Published Date
: Mar 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Berberine
Diseases
:
Diabetes Mellitus: Type 2
,
Insulin Resistance
,
Metabolic Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hypoglycemic Agents
,
Hypolipidemic
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The hypotensive and anti-inflammatory effect of soy nut consumption may be due to a reduction in solube vascular cell adhesion molecule-1 which results in an improvement in endothelial function.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Am J Cardiol. 2008 Jul 1;102(1):84-6. Epub 2008 Apr 16. PMID:
18572041
Article Published Date
: Jul 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Isoflavones
,
Soy Protein
Diseases
:
C-Reactive Protein
,
Hypertension
,
Inflammation
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Vascular Cell Adhesion Molecule-1 Inhibitor
[+]
The regular practice of physical activity exerts beneficial effects on body composition and the anti-inflammatory status of old people
Nov 15, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2018 Nov 16 ;10(11). Epub 2018 Nov 16. PMID:
30453505
Article Published Date
: Nov 15, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Inflammation
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The results concluded that inflammation as a major cause of hypertension was significantly decreased in patients using olive leaf extract tablets.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pak J Biol Sci. 2019 Jan ;22(7):342-348. PMID:
31930845
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Olive leaf extract
Diseases
:
Hypertension
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The results of this pilot study showed that the efficacy of Althaea officinalis 1% ointment in a decrease of disease severity is more than hydrocortisone.
Oct 08, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Oct 9. Epub 2020 Oct 9. PMID:
33034099
Article Published Date
: Oct 08, 2020
Study Type
: Human Study
Additional Links
Substances
:
Marshmallow Root
Diseases
:
Atopic Dermatitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
The results of this study showed that pre-operative melatonin administration could modify inflammatory cytokines secretion such as IL-6.
Feb 29, 2020
Click here to read the entire abstract
Pubmed Data
: Asian J Anesthesiol. 2020 Mar 1 ;58(1):35-44. Epub 2020 Mar 26. PMID:
33081432
Article Published Date
: Feb 29, 2020
Study Type
: Human Study
Additional Links
Substances
:
Melatonin
Diseases
:
Cardiac Surgery
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
The roles of physical activity and inflammation in mortality, cognition, and depressive symptoms among older Mexican Americans.
Oct 31, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Epidemiol. 2019 Nov 1 ;188(11):1944-1952. PMID:
31497846
Article Published Date
: Oct 31, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Cognitive Decline/Dysfunction
,
Dementia
,
Depression
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Physical Activity
[+]
The use of black raspberry improved cardiovascular risks in patients with metabolic syndrome during the 12-week follow-up.
Mar 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2016 Apr ;19(4):346-52. Epub 2016 Feb 18. PMID:
26891216
Article Published Date
: Mar 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Black Raspberry
Diseases
:
Cardiovascular Disease: Prevention
,
Metabolic Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
These findings point to possible benefits of yoga on IL-6 in depressed populations.
May 28, 2019
Click here to read the entire abstract
Pubmed Data
: Behav Med. 2019 May 29:1-10. Epub 2019 May 29. PMID:
31141465
Article Published Date
: May 28, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Depression
,
Inflammation
Therapeutic Actions
:
Yoga
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
These results demonstrated that an oral intake of royal jelly suppressed anorexia and fatigue in renal cell carcinoma patients.
Oct 08, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Sci (Basel). 2020 Oct 9 ;8(4). Epub 2020 Oct 9. PMID:
33050250
Article Published Date
: Oct 08, 2020
Study Type
: Human Study
Additional Links
Substances
:
Royal Jelly
Diseases
:
Cachexia: Cancer
,
Cancer: Fatigue
,
Kidney Cancer
Pharmacological Actions
:
Anti-Cachexic Agents
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
This study showed beneficial effects of CoQ10 supplementation on inflammatory cytokines and oxidative stress in rheumatoid arthritis patients.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Arch Med Res. 2015 Oct ;46(7):527-33. Epub 2015 Sep 3. PMID:
26342738
Article Published Date
: Sep 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Oxidative Stress
,
Rheumatoid Arthritis
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Tocotrienols attenuate UV-induced inflammaging.
Jun 01, 2018
Click here to read the entire abstract
Pubmed Data
: J Cosmet Dermatol. 2018 Jun ;17(3):555-565. Epub 2017 Sep 26. PMID:
28952200
Article Published Date
: Jun 01, 2018
Study Type
: Human Study
Additional Links
Substances
:
Tocotrienols
Diseases
:
Oxidative Stress
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
[+]
Tripterygium wilfordii has a synergistic effect on the efficacy of prednisone in the treatment of myasthenia gravis.
Mar 01, 2002
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Mar;22(3):175-7. PMID:
12585099
Article Published Date
: Mar 01, 2002
Study Type
: Human Study
Additional Links
Substances
:
Thunder god vine
,
Tripterygium wilfordii
Diseases
:
Myasthenia Gravis
Pharmacological Actions
:
Interleukin-6 Downregulation
Additional Keywords
:
Drug-Plant-Vitamin Synergies
,
Drug Sparing
[+]
Ubiquinol + L-carnitine can cause a significant reduction in the pro-inflammatory cytokines in patients with heart failure.
Aug 01, 2007
Click here to read the entire abstract
Pubmed Data
: Acta Cardiol. 2007 Aug;62(4):349-54. PMID:
17824295
Article Published Date
: Aug 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Carnitine
,
Coenzyme Q10
,
Ubiquinol
Diseases
:
Heart Failure
Pharmacological Actions
:
Interleukin-6 Downregulation
[+]
Vitamin C and E may reduce the cortisol response to a single 2.5 hour bout of prolonged exercise.
Apr 01, 2007
Click here to read the entire abstract
Pubmed Data
: Med Sci Sports Exerc. 2007 Apr;39(4):645-52. PMID:
17414802
Article Published Date
: Apr 01, 2007
Study Type
: Human Study
Additional Links
Substances
:
Antioxidant formulas
,
Vitamin C
,
Vitamin E
Diseases
:
Athletic Performance: Recovery
,
Cortisol: High
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
[+]
Vitamin C can significantly treat and reduce the inflammation, as measured by hs-CRP and IL-6, in hypertensive and/or diabetic adults and also helps to reduce FBG levels.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2015 ;9:3405-12. Epub 2015 Jul 1. PMID:
26170625
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
C-Reactive Protein
,
Diabetes Mellitus: Type 2
,
Hypertension
,
Inflammation
,
Obesity
,
Oxidative Stress
,
Triglycerides: Elevated
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoglycemic Agents
,
Interleukin-6 Downregulation
Additional Keywords
:
Significant Treatment Outcome
[+]
Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2014 ;2014:426740. Epub 2014 Aug 1. PMID:
25253919
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
,
Pneumonia
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin C supplementation prevented endurance exercise-induced lipid peroxidation and muscle damage but had no effect on inflammatory markers.
May 31, 2008
Click here to read the entire abstract
Pubmed Data
: J Sports Med Phys Fitness. 2008 Jun ;48(2):217-24. PMID:
18427418
Article Published Date
: May 31, 2008
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Lipid Peroxidation
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Interleukin-6 Downregulation
[+]
Vitamin D administration can significantly reduce the IL-6 as prognostic marker in ventilator-associated pneumonia patients.
Sep 11, 2017
Click here to read the entire abstract
Pubmed Data
: J Crit Care. 2017 Sep 12 ;44:300-305. Epub 2017 Sep 12. PMID:
29248753
Article Published Date
: Sep 11, 2017
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Pneumonia: Ventilator-associated
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Vitamin D supplementation effectively reduced circulatory YKL-40 and MCP-1 levels in patients with type-2 diabetes and vitamin D deficiency.
Jul 28, 2019
Click here to read the entire abstract
Pubmed Data
: Diabetes Metab Syndr. 2019 Jul 29 ;13(5):2873-2877. Epub 2019 Jul 29. PMID:
31425951
Article Published Date
: Jul 28, 2019
Study Type
: Human Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Diabetes Mellitus: Type 2
,
Diabetic Complications
,
Vitamin D Deficiency
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Weight reducing program modulates inflammatory cytokines, adipocytokines and endothelial function biomarkers among obese T2DM patients.
Aug 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Afr Health Sci. 2020 Sep ;20(3):1329-1336. PMID:
33402982
Article Published Date
: Aug 31, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Diabetes Mellitus: Type 2
,
Endothelial Dysfunction
Therapeutic Actions
:
Weight Reduction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Weight reduction improves immune system and inflammatory cytokines in obese asthmatic patients.
May 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Afr Health Sci. 2020 Jun ;20(2):897-902. PMID:
33163057
Article Published Date
: May 31, 2020
Study Type
: Human Study
Additional Links
Diseases
:
Asthma
,
Inflammation
,
Obesity
Therapeutic Actions
:
Weight Reduction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Whole apple consumption may be an effective dietary strategy to mitigate obesity-associated inflammation.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID:
31224358
Article Published Date
: May 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Apple
Diseases
:
Inflammation
,
Obesity
,
Overweight
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Yerba mate tea may help decrease oxidative stress and low-grade inflammation.
Jul 01, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Food Sci Nutr. 2018 Jul 2:1-10. Epub 2018 Jul 2. PMID:
29962254
Article Published Date
: Jul 01, 2018
Study Type
: Human Study
Additional Links
Substances
:
Yerba Mate
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Z. multiflora reduced inflammation and improved pulmonary function tests indices in sulfur mustard-exposed patients.
Nov 06, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 Nov 7:112325. Epub 2019 Nov 7. PMID:
31707049
Article Published Date
: Nov 06, 2019
Study Type
: Human Study
Additional Links
Substances
:
Zataria multiflora
Diseases
:
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-2 Downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
Problem Substances
:
Mustard Gas
[+]
A Polyphenol-rich pomegranate fruit extract suppresses NF-κB and IL-6 expression.
Mar 08, 2017
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2017 Mar 9. Epub 2017 Mar 9. PMID:
28276100
Article Published Date
: Mar 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chondroprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Astaxanthin could be useful for improving chronic inflammation such as that associated with oral lichen planus.
Apr 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Biochem Nutr. 2015 May ;56(3):171-8. Epub 2015 Jan 29. PMID:
26060346
Article Published Date
: Apr 30, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Astaxanthin
Diseases
:
Oral Lichen Planus
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bamboo leaf extracts may be clinically useful as an anti-inflammatory or anti-oxidant for human cardiovascular disease.
Jan 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Res Pract. 2013 Feb ;7(1):9-14. Epub 2013 Feb 4. PMID:
23422838
Article Published Date
: Jan 31, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Bamboo
Diseases
:
Cardiovascular Diseases
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Carnosol inhibits pro-inflammatory and catabolic mediators of cartilage breakdown in human osteoarthritic chondrocytes.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(8):e0136118. Epub 2015 Aug 20. PMID:
26292290
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Carnosol
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Cinnamaldehyde and eugenol were found to exert potent anti-inflammatory and anti-oxidant effects on the PBMC culture of rheumatoid arthritis patients.
Jun 04, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 Jun 5 ;852:14-24. Epub 2019 Feb 20. PMID:
30796902
Article Published Date
: Jun 04, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Cinnamaldehyde
,
Eugenol
Diseases
:
Oxidative Stress
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Combination treatments with luteolin and fisetin may be a potential candidate for the treatment and prevention of diabetes and its complications.
Jun 25, 2017
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2017 Jun 26. Epub 2017 Jun 26. PMID:
28650731
Article Published Date
: Jun 25, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Fisetin
,
Luteolin
Diseases
:
Diabetic Complications
,
Hyperglycemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substance Synergy
[+]
Curcumin may offer a viable alternative for the prevention or control of HIV replication in the female genital tract.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(4):e0124903. Epub 2015 Apr 9. PMID:
25856395
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Herpes Simplex Virus Type 2
,
HIV Infections
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-Retroviral Agents
,
Antiviral Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Diosmetin exhibits anti-proliferative and anti-inflammatory effects on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.
Dec 12, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 Dec 13. Epub 2019 Dec 13. PMID:
31833613
Article Published Date
: Dec 12, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Diosmetin
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
[+]
Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Dec 24 ;194:83-90. Epub 2016 Aug 23. PMID:
27566200
Article Published Date
: Dec 23, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Inflammatory cytokines upregulate transferrin synthesis, which may increase aluminum absorption by the brain after vaccination.
Sep 01, 2000
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2000 Sep-Oct;20(5A):3331-8. PMID:
11062761
Article Published Date
: Sep 01, 2000
Study Type
: Human In Vitro
Additional Links
Diseases
:
Vaccine-induced Toxicity
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Anti Therapeutic Actions
:
Vaccination: All
Problem Substances
:
Vaccine Adjuvants
Adverse Pharmacological Actions
:
Neurotoxic
[+]
Neferine exerts a cytoprotective effect against hypoxia-induced oxidative stress and inflammation in human peripheral blood mononuclear cells.
Jul 08, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Jul 9 ;93:730-736. Epub 2017 Jul 9. PMID:
28700977
Article Published Date
: Jul 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Lotus
Diseases
:
Hypoxia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cytoprotective
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Cosmet Sci. 2020 Oct ;42(5):501-511. Epub 2020 Aug 20. PMID:
32657437
Article Published Date
: Sep 30, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Niacinamide
Diseases
:
Inflammation
,
Skin Diseases: Inflammatory
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Postaglandin PGE2 downregulation
[+]
Oleocanthal inhibits catabolic and inflammatory mediators in LPS-activated human primary osteoarthritis chondrocytes.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;49(6):2414-2426. Epub 2018 Sep 27. PMID:
30261513
Article Published Date
: Dec 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Oleocanthal
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oleuropein might provide a basis for developing a new dietary strategy for the prevention and management of rheumatoid arthritis.
Apr 19, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 Apr 20. Epub 2017 Apr 20. PMID:
28426090
Article Published Date
: Apr 19, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Oleuropein
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oligonol suppresses inflammatory cytokine production from human monocytes.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Hum Immunol. 2016 Jun ;77(6):512-5. Epub 2016 Apr 11. PMID:
27079270
Article Published Date
: May 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Lychee
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Paeoniflorin may provide a new therapeutic approach to regulate P2X7R-mediated pathologic responses of primary Sjögren's syndrome.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Sep ;28(1):115-20. Epub 2015 Jun 3. PMID:
26049028
Article Published Date
: Aug 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Sjogren's Syndrome
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Phloretin inhibits interleukin-1β-induced COX-2 and ICAM-1 in human lung epithelial cells.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2015 Jun ;6(6):1960-7. PMID:
25996641
Article Published Date
: May 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Phloretin
Diseases
:
Experimental Lung Inflammation
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Prostaglandin PGE2 downregulation
[+]
Pomegranate juice attenuated the damaging effects of cigarette smoke on cultured human alveolar cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Chron Obstruct Pulmon Dis. 2016 ;11:227-37. Epub 2016 Feb 3. PMID:
26893554
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Inflammation
,
Lung Injury: Smoke-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Punicalagin and EGCG can rescue keratinocyte viability and attenuate the inflammatory responses of cells due to airborne particles.
Mar 21, 2018
Click here to read the entire abstract
Pubmed Data
: Skin Pharmacol Physiol. 2018 Mar 22 ;31(3):134-143. Epub 2018 Mar 22. PMID:
29566388
Article Published Date
: Mar 21, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
,
Punicalagin
Diseases
:
Air Pollution Linked Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Resveratrol may be a useful preventative therapeutic for pregnancies complicated by inflammation and insulin resistance.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(3):e0173373. Epub 2017 Mar 9. PMID:
28278187
Article Published Date
: Dec 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Gestational Diabetes
,
Inflammation
,
Pregnancy Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 alpha downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Rosmarinic acid may be a potential candidate for the treatment of psoriasis.
Jun 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jun 15 ;155:189-94. Epub 2016 May 17. PMID:
27210890
Article Published Date
: Jun 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Rosmarinic acid
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
These results suggest that HEABG may be effective in the prevention and treatment of endometriosis in humans.
Jun 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2013 Jul ;32(1):67-78. Epub 2013 Apr 25. PMID:
23619991
Article Published Date
: Jun 30, 2013
Study Type
: Human In Vitro
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Endometriosis
Pharmacological Actions
:
Antiproliferative
,
Cell cycle arrest
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Thymoquinone represents a prospective treatment option to combat Mycobacterium tuberculosis infection.
May 24, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 May 25 ;17(1):279. Epub 2017 May 25. PMID:
28545436
Article Published Date
: May 24, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Thymoquinone
Diseases
:
Mycobacterium tuberculosis
Pharmacological Actions
:
Anti-Bacterial Agents
,
Interleukin-6 Downregulation
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Vitamin D attenuates human gingival fibroblast inflammatory cytokine production following advanced glycation end product interaction with receptors for AGE.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Periodontal Res. 2019 Apr ;54(2):154-163. Epub 2018 Oct 8. PMID:
30295316
Article Published Date
: Mar 31, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitamin D
Diseases
:
Advanced Glycation End products (AGE)
,
Endotoxemia
,
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
Vitexin alleviates interleukin-1β induced inflammatory responses in chondrocytes from osteoarthritis patients.
May 03, 2019
Click here to read the entire abstract
Pubmed Data
: Scand J Immunol. 2019 May 4:e12773. Epub 2019 May 4. PMID:
31055848
Article Published Date
: May 03, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitexins
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
α-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.
Jan 01, 2014
Click here to read the entire abstract
Pubmed Data
: Curr Pharm Biotechnol. 2014 ;15(2):173-81. PMID:
24894548
Article Published Date
: Jan 01, 2014
Study Type
: Animal Study, Human In Vitro
Additional Links
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginger efficiently reduced the lung damage and protected the lungs from severe damage due to hyperoxia and inflammation.
Aug 15, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Med Sci. 2018 Aug 16 ;48(4):892-900. Epub 2018 Aug 16. PMID:
30121057
Article Published Date
: Aug 15, 2018
Study Type
: Human: Case Report
Additional Links
Substances
:
Ginger
Diseases
:
Bronchopulmonary Dysplasia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines.
Aug 17, 2020
Click here to read the entire abstract
Pubmed Data
: Cancer Chemother Pharmacol. 2020 Aug 18. Epub 2020 Aug 18. PMID:
32812061
Article Published Date
: Aug 17, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Chemoprotective Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory effect of a flavonoid-rich extract of orange juice in adult zebrafish subjected to Vibrio anguillarum-induced enteritis.
Apr 26, 2020
Click here to read the entire abstract
Pubmed Data
: Nat Prod Res. 2020 Apr 27:1-4. Epub 2020 Apr 27. PMID:
32338069
Article Published Date
: Apr 26, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Orange
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Hydroxytyrosol ameliorates oxidative challenge and inflammatory response associated with lipopolysaccharide-mediated sepsis.
Aug 24, 2020
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2020 Aug 25:960327120949618. Epub 2020 Aug 25. PMID:
32840384
Article Published Date
: Aug 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Hydroxytyrosol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Oleuropein protects against lipopolysaccharide-induced sepsis and alleviates inflammatory responses in mice.
Jul 24, 2020
Click here to read the entire abstract
Pubmed Data
: IUBMB Life. 2020 Jul 25. Epub 2020 Jul 25. PMID:
32710811
Article Published Date
: Jul 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The protective effect of vitexinin septic encephalopathy by reducing leukocyte-endothelial adhesion and inflammatory response.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Palliat Med. 2020 Jul ;9(4):2079-2089. Epub 2020 Jul 14. PMID:
32692224
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Vitexins
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.
Jan 05, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: JCI Insight. 2018 09 6 ;3(17). Epub 2018 Sep 6. PMID:
30185660
Article Published Date
: Jan 05, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Bone Fractures
,
Wound Healing
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
1,8-cineol appears to be able to augment protection against influenza viral infection in mice.
Jul 31, 2016
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2016 Aug ;39(4):1582-93. PMID:
27351430
Article Published Date
: Jul 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Eucalyptus
Diseases
:
Inflammation
,
Influenza
,
Pneumonia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interferon Gamma Reducer
,
Interleukin-10 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
13 weeks of swim training could reverse HFD-induced metabolic disorders including insulin resistance and inflammation.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Endocrinol. 2017 ;2017:5940732. Epub 2017 Sep 10. PMID:
29081799
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
High Fat Diet
,
Inflammation
,
Insulin Resistance
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Insulin Sensitizers
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevents lipopolysaccharide-induced depressive-like behaviours.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Behav Pharmacol. 2017 08 ;28(5):365-374. PMID:
28410266
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Anxiety
,
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
5-hydroxytryptophan attenuates imiquimod-induced psoriasiform dermatitis.
Jan 10, 2018
Click here to read the entire abstract
Pubmed Data
: Exp Dermatol. 2018 11 ;27(11):1273-1279. Epub 2018 Oct 9. PMID:
30221419
Article Published Date
: Jan 10, 2018
Study Type
: Animal Study
Additional Links
Substances
:
5-HTP (5-Hydroxytryptophan)
Diseases
:
Dermatitis
,
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Nov ;107:1523-1529. Epub 2018 Sep 5. PMID:
30257370
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gingerol
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries.
Jul 14, 2020
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2020 Jul 15:173294. Epub 2020 Jul 15. PMID:
32681941
Article Published Date
: Jul 14, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Gingerol
Diseases
:
Brain Inflammation
,
Brain Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
[+]
6-Gingerol exerts protective effects against ischemia reperfusion induced intestinal mucosa injury.
Feb 03, 2017
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2017 Feb 4 ;119:137-148. Epub 2017 Feb 4. PMID:
28167239
Article Published Date
: Feb 03, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Ischemia
Pharmacological Actions
:
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Shogaol ameliorates diabetic nephropathy through anti-inflammatory, hyperlipidemic, anti-oxidative activity.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Jan ;97:633-641. Epub 2017 Nov 6. PMID:
29101807
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hypolipidemic
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
6-Shogaol reduces progression of experimental endometriosis.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Korean J Physiol Pharmacol. 2018 Nov ;22(6):627-636. Epub 2018 Oct 25. PMID: