Interleukin-18 down-regulation

Views 187
Jump to
Abstracts Focused Research Topics
Your Token Count0

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
45 Substances Researched for Interleukin-18 down-regulation
NameACCKFocus
Ginsenosides612Locked
Cherry: All Varieties110Locked
Cherry: Bing110Locked
Apigenin36Locked
Astragaloside24Locked
Biochanin A24Locked
Emodin24Locked
Procyanidin B2 24Locked
Thymoquinone24Locked
Ursolic Acid24Locked
Resveratrol23Locked
Arctigenin12Locked
Betulinic acid12Locked
Cabbage12Locked
Celastrol12Locked
Cyanidin 3-glucoside12Locked
Flavonoids12Locked
Galactooligosaccharides12Locked
Gastrodin12Locked
Green Tea12Locked
Gynostemma12Locked
Kaempferol12Locked
Ligustrazine12Locked
Mangiferin12Locked
Modified Arabinoxylan Rice Bran (MGN-3)12Locked
Persimmon 12Locked
Polyphenols12Locked
Pomegranate12Locked
Puerarin12Locked
Quercetin12Locked
Raspberry12Locked
Sulforaphane12Locked
Theaflavins12Locked
Allicin11Locked
Alpha-Lipoic Acid11Locked
Berberine11Locked
Citrus naringin11Locked
Coriolus versicolor11Locked
Curcumin11Locked
Dogwood11Locked
Nobiletin 11Locked
Olive11Locked
Oridonin11Locked
Safflower11Locked
Vitamin E: Gamma-tocotrienol11Locked

View the Evidence:
70 Abstracts with Interleukin-18 down-regulation Research

[+]

Far infrared radiation therapy provides an effective treatment modality for patients with chronic lymphedema.May 31, 2017

Pubmed Data : Arch Gynecol Obstet. 2017 Jun ;295(6):1441-1450. Epub 2017 Apr 22. PMID: 28434105
Article Published Date : May 31, 2017
Study Type : Human Study
Additional Links
Diseases : Lymphedema
Therapeutic Actions : Thermal Therapy: Far-Infrared
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-18 down-regulation, Interleukin-2 Downregulation
[+]

Long-term bicycle riding improves the quality of life and reduces the severity of depression in patients suffering from chronic hemodialysis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychiatr Dis Treat. 2017 ;13:91-100. Epub 2016 Dec 28. PMID: 28096677
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Hemodialysis
Therapeutic Actions : Exercise: Cycling
Pharmacological Actions : Antidepressive Agents, Interleukin-18 down-regulation, Interleukin-6 Downregulation
[+]

Sweet bing cherries lower circulating concentrations of markers for chronic inflammatory diseases in healthy humans.Feb 28, 2013

Pubmed Data : J Nutr. 2013 Mar ;143(3):340-4. Epub 2013 Jan 23. PMID: 23343675
Article Published Date : Feb 28, 2013
Study Type : Human Study
Additional Links
Substances : Cherry: All Varieties, Cherry: Bing
Diseases : C-Reactive Protein, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Endothelin-1 Inhibitor, Epidermal growth factor receptor (EGFR) inhibitor, Interleukin-18 down-regulation
Additional Keywords : Phytotherapy
[+]

Antitumor and immunomodulatory activities of total flavonoids extract from persimmon leaves in H 22 liver tumor-bearing mice.Jul 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Jul 12 ;8(1):10523. Epub 2018 Jul 12. PMID: 30002398
Article Published Date : Jul 11, 2018
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Persimmon
Diseases : Liver Cancer
Pharmacological Actions : Immunomodulatory, Interleukin-18 down-regulation
Additional Keywords : Plant Extracts
[+]

Apigenin ameliorates HFD-induced NAFLD through regulation of the XO/NLRP3 pathways.Jun 13, 2019

Pubmed Data : J Nutr Biochem. 2019 Jun 14 ;71:110-121. Epub 2019 Jun 14. PMID: 31325892
Article Published Date : Jun 13, 2019
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Apigenin supplement might provide a basis for developing a new dietary strategy for the prevention of chronic ulcerative colitis.Mar 31, 2016

Pubmed Data : J Nutr Biochem. 2016 Apr ;30:143-52. Epub 2016 Jan 4. PMID: 27012631
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Arctigenin may confer protection against ischemic stroke.Nov 03, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 Nov 4 ;493(1):821-826. Epub 2017 Sep 6. PMID: 28888980
Article Published Date : Nov 03, 2017
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Stroke: Ischemic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Astragaloside IV attenuates inflammatory response mediated by NLRP-3/calpain-1 is involved in the development of pulmonary hypertension.Dec 07, 2020

Pubmed Data : J Cell Mol Med. 2020 Dec 8. Epub 2020 Dec 8. PMID: 33295020
Article Published Date : Dec 07, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Hypertension: Pulmonary
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Astragaloside IV treatment ameliorated the severity of diabetic nephropathy.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:9542165. Epub 2020 Aug 12. PMID: 32855769
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Renoprotective
[+]

Biochanin A attenuates myocardial ischemia/reperfusion injury through the TLR4/NF-κB/NLRP3 signaling pathway.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Cir Bras. 2019 ;34(11):e201901104. Epub 2019 Dec 20. PMID: 31859817
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Myocardial Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Biochanin A protects against angiotensin II-induced damage of dopaminergic neurons.Jan 11, 2019

Pubmed Data : Behav Pharmacol. 2019 12 ;30(8):700-711. PMID: 31703032
Article Published Date : Jan 11, 2019
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Brain Inflammation , Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cabbage extracts have a pancreato-protective effect.Jan 19, 2017

Pubmed Data : Nat Prod Res. 2017 Jan 20:1-4. Epub 2017 Jan 20. PMID: 28107794
Article Published Date : Jan 19, 2017
Study Type : Animal Study
Additional Links
Substances : Cabbage
Diseases : Alcohol Toxicity , Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Pancreato Protective Agents
Additional Keywords : Alcohol Toxicity, Anti-Inflammatory Agents, Antioxidants, Cabbage, Pancreatitis, Plant Extracts
[+]

Celastrol inhibits microglial pyroptosis and attenuates inflammatory reaction in acute spinal cord injury rats.Dec 31, 2018

Pubmed Data : Int Immunopharmacol. 2019 Jan ;66:215-223. Epub 2018 Nov 22. PMID: 30472522
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Celastrol
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Crocin alleviates the inflammation and oxidative stress responses associated with diabetic nephropathy.Apr 25, 2021

Pubmed Data : Life Sci. 2021 Apr 26 ;278:119542. Epub 2021 Apr 26. PMID: 33915128
Article Published Date : Apr 25, 2021
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effect of fucoidan on ethanol-induced liver injury and steatosis in mice and the underlying mechanism.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2021 ;65. Epub 2021 Apr 20. PMID: 33994911
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-18 down-regulation, Interleukin-6 Downregulation
[+]

Electro-acupuncture alleviates chronic unpredictable stress-induced depressive- and anxiety-like behaviour and neuroinflammation.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Mol Neurosci. 2018 ;11:149. Epub 2018 May 31. PMID: 29946236
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Depression
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-18 down-regulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Emodin alleviated pancreatic and intestinal mucosa injury in experimental severe acute pancreatitis.Aug 14, 2017

Pubmed Data : Hepatobiliary Pancreat Dis Int. 2017 Aug 15 ;16(4):431-436. PMID: 28823375
Article Published Date : Aug 14, 2017
Study Type : Animal Study
Additional Links
Substances : Emodin
Diseases : Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Emodin attenuates severe acute pancreatitis via antioxidant and anti-inflammatory activity.Nov 30, 2019

Pubmed Data : Inflammation. 2019 Dec ;42(6):2129-2138. PMID: 31605249
Article Published Date : Nov 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Emodin
Diseases : Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-18 down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Galactooligosaccharides protects against DSS-induced murine colitis.Jan 31, 2020

Pubmed Data : Life Sci. 2020 Feb 1 ;242:117220. Epub 2019 Dec 24. PMID: 31881230
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Substances : Galactooligosaccharides
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, interleukin-13 down-regulation, Interleukin-18 down-regulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Gastrodin alleviates cerebral ischaemia/reperfusion injury.Jun 30, 2021

Pubmed Data : Neurochem Res. 2021 Jul ;46(7):1747-1758. Epub 2021 Apr 11. PMID: 33839999
Article Published Date : Jun 30, 2021
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Gastrodin is anti-inflammatory as it effectively suppresses inflammasome in oxygen-glucose-deprivation-stimulated astrocytes.Jun 18, 2019

Pubmed Data : Neuromolecular Med. 2019 Jun 19. Epub 2019 Jun 19. PMID: 31218587
Article Published Date : Jun 18, 2019
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-18 down-regulation, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Geraniol isolated from lemon grass to mitigate doxorubicin-induced cardiotoxicity through Nrf2 and NF-κB signaling.Jul 30, 2021

Pubmed Data : Chem Biol Interact. 2021 Jul 31 ;347:109599. Epub 2021 Jul 31. PMID: 34343525
Article Published Date : Jul 30, 2021
Study Type : Animal Study
Additional Links
Substances : Geraniol
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Chemoprotective Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginsenoside Rg1 alleviates acute liver injury through the induction of autophagy.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2021 ;18(6):1382-1389. Epub 2021 Jan 23. PMID: 33628094
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Ginsenoside Rg1 can inhibit inflammatory reaction, regulate lipid metabolism, and alleviate liver injury in NAFLD.May 18, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ACS Omega. 2020 May 19 ;5(19):10878-10890. Epub 2020 May 5. PMID: 32455208
Article Published Date : May 18, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic, Interleukin-18 down-regulation, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Ginsenoside Rg1 may have protective effects on neuroinflammation and neuronal injury induced by chronic glucocorticoids exposure.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2017 Oct ;40(4):1134-1142. Epub 2017 Aug 9. PMID: 28849171
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
Problem Substances : Dexamethasone
[+]

Ginsenoside Rg1 protects mice against streptozotocin-induced type 1 diabetes. Jan 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Pharmacol. 2020 Jan 5 ;866:172801. Epub 2019 Nov 16. PMID: 31738935
Article Published Date : Jan 04, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Nrf2 activation
[+]

Green tea polyphenols prevent lipopolysaccharide-induced inflammatory liver injury.Jun 11, 2019

Pubmed Data : Food Funct. 2019 Jun 12. Epub 2019 Jun 12. PMID: 31187838
Article Published Date : Jun 11, 2019
Study Type : Animal Study
Additional Links
Substances : Green Tea, Polyphenols
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Gypenosides improve diabetic cardiomyopathy by inhibiting ROS‐mediated NLRP3 inflammasome activation.Dec 31, 2017

Pubmed Data : J Cell Mol Med. 2018 09 ;22(9):4437-4448. Epub 2018 Jul 11. PMID: 29993180
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Gynostemma
Diseases : Cardiomyopathy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
Additional Keywords : Plant Extracts
[+]

Intermittent fasting attenuates inflammasome activity in ischemic stroke.Jun 30, 2014

Pubmed Data : Exp Neurol. 2014 Jul ;257:114-9. Epub 2014 May 5. PMID: 24805069
Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Diseases : Stroke: Ischemic
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Kaempferol might be a novel promising therapeutic agent for spinal cord injury.Apr 02, 2021

Pubmed Data : Free Radic Biol Med. 2021 Apr 3 ;168:142-154. Epub 2021 Apr 3. PMID: 33823244
Article Published Date : Apr 02, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Kaempferol
Diseases : Inflammation, Oxidative Stress, Spinal Cord Injuries
Pharmacological Actions : Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

LED therapy can attenuate neuroinflammatory responses and tissue damage following ischemic stroke.Feb 05, 2017

Pubmed Data : J Biophotonics. 2017 Feb 6. Epub 2017 Feb 6. PMID: 28164443
Article Published Date : Feb 05, 2017
Study Type : Animal Study
Additional Links
Diseases : Stroke: Ischemic
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Mangiferin inhibits hippocampal NLRP3 inflammasome and exerts antidepressant effects.Apr 12, 2017

Pubmed Data : Behav Pharmacol. 2017 Apr 13. Epub 2017 Apr 13. PMID: 28410265
Article Published Date : Apr 12, 2017
Study Type : Animal Study
Additional Links
Substances : Mangiferin
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

MGN-3 and its hydrolysate significantly alleviated D-galactosamine induced hepatitis in rats.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Biotechnol Biochem. 2012 ;76(5):942-6. Epub 2012 May 7. PMID: 22738964
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Modified Arabinoxylan Rice Bran (MGN-3)
Diseases : Chemically-Induced Liver Damage, Hepatitis
Pharmacological Actions : Hepatoprotective, Interleukin-18 down-regulation
[+]

Pinocembrin inhibited cardiomyocyte pyroptosis against doxorubicin-induced cardiac dysfunction.May 31, 2021

Pubmed Data : Int Immunopharmacol. 2021 Jun ;95:107533. Epub 2021 Mar 19. PMID: 33752080
Article Published Date : May 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Chemoprotective Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Nrf2 activation
[+]

Pomegranate juice can be potentially used for the treatment of inflammatory bowel disease.Jun 27, 2016

Pubmed Data : Mol Cell Biochem. 2016 Jun 28. Epub 2016 Jun 28. PMID: 27352379
Article Published Date : Jun 27, 2016
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Procyanidin B2 prevents lupus nephritis development in mice by inhibiting NLRP3 inflammasome activation.Jun 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Innate Immun. 2018 Jul ;24(5):307-315. Epub 2018 Jun 6. PMID: 29874961
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Procyanidin B2
Diseases : Lupus Nephritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Procyanidin B2 protects rats from paraquat-induced acute lung injury.Sep 30, 2018

Pubmed Data : Immunobiology. 2018 Oct ;223(10):555-561. Epub 2018 Jul 6. PMID: 30025709
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Procyanidin B2
Diseases : Pesticide Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
Problem Substances : Paraquat
[+]

Protective effect of ginsenoside metabolite compound K against diabetic nephropathy.Sep 30, 2018

Pubmed Data : Int Immunopharmacol. 2018 Oct ;63:227-238. Epub 2018 Aug 11. PMID: 30107367
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Renoprotective
[+]

Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation.Mar 06, 2020

Pubmed Data : Pharmacol Res. 2020 Mar 7 ;155:104746. Epub 2020 Mar 7. PMID: 32156650
Article Published Date : Mar 06, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Renoprotective
[+]

Puerarin has the capability of inhibiting vascular calcification in uremic rats by inhibiting inflammation.Jul 14, 2019

Pubmed Data : Eur J Pharmacol. 2019 Jul 15 ;855:235-243. Epub 2019 May 11. PMID: 31085237
Article Published Date : Jul 14, 2019
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Vascular Calcification
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway.Jun 09, 2021

Pubmed Data : Sci China Life Sci. 2021 Jun 10. Epub 2021 Jun 10. PMID: 34125371
Article Published Date : Jun 09, 2021
Study Type : Animal Study
Additional Links
Substances : Punicalagin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Quercetin protects against diabetic encephalopathy via SIRT1/NLRP3 pathway in db/db miceJan 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2020 Jan 30. Epub 2020 Jan 30. PMID: 32000299
Article Published Date : Jan 29, 2020
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Diabetic Complications, Encephalopathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Red raspberries suppress NLRP3 inflammasome and attenuate metabolic abnormalities in diet-induced obese mice.Nov 01, 2017

Pubmed Data : J Nutr Biochem. 2017 Nov 2 ;53:96-103. Epub 2017 Nov 2. PMID: 29202274
Article Published Date : Nov 01, 2017
Study Type : Animal Study
Additional Links
Substances : Raspberry
Diseases : Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Resveratrol prevents inflammation-dependent hepatic melanoma metastasis.Jan 01, 2011

Pubmed Data : J Transl Med. 2011 ;9:59. Epub 2011 May 12. PMID: 21569399
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Inflammation, Liver Cancer, Liver Cancer: Metastatic, Melanoma: Metastatic
Pharmacological Actions : Anti-metastatic, Antiproliferative , Interleukin-18 down-regulation, Vascular Cell Adhesion Molecule-1 Inhibitor
[+]

Sulforaphane improves outcomes and slows cerebral ischemic/reperfusion injuryFeb 08, 2017

Pubmed Data : Int Immunopharmacol. 2017 Feb 9 ;45:74-78. Epub 2017 Feb 9. PMID: 28189971
Article Published Date : Feb 08, 2017
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Synergistic effect of betulinic acid, apigenin and skimmianine (BASk) in high cholesterol diet.May 31, 2021

Pubmed Data : Cytokine. 2021 Jun ;142:155475. Epub 2021 Mar 2. PMID: 33667961
Article Published Date : May 31, 2021
Study Type : Animal Study
Additional Links
Substances : Apigenin, Betulinic acid
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
Additional Keywords : Natural Substance Synergy
[+]

Tetramethylpyrazine ameliorates experimental autoimmune encephalomyelitis by modulating the inflammatory response.Jul 31, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 Aug 1. Epub 2018 Aug 1. PMID: 30078676
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Multiple Sclerosis
Pharmacological Actions : Interleukin-10 upregulation, Interleukin-17 downregulation, Interleukin-18 down-regulation
[+]

The present findings indicated that ursolic acid may be a possible therapeutic agent against diabetic nephropathy.Oct 31, 2018

Pubmed Data : Mol Med Rep. 2018 Nov ;18(5):4675-4681. Epub 2018 Sep 3. PMID: 30221655
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : Diabetic Nephropathy, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The study is the first to demonstrate strong effects of cyanidin-3-O-glucosideto alleviate DSS-induced colonic damage.Aug 19, 2019

Pubmed Data : Inflamm Bowel Dis. 2019 Aug 20 ;25(9):1510-1521. PMID: 31107535
Article Published Date : Aug 19, 2019
Study Type : Animal Study
Additional Links
Substances : Cyanidin 3-glucoside
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective, Interleukin-18 down-regulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Theaflavin alleviates inflammatory response and brain injury induced by cerebral hemorrhage.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2018 ;12:1609-1619. Epub 2018 Jun 12. PMID: 29928110
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Theaflavins
Diseases : Brain Inflammation , Cerebral Hemorrhage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Thymoquinone effectively modulates autophagy, pyroptosis, and pro-inflammatory, making it important in the treatment of sepsis-induced cardiac damage.Oct 19, 2018

Pubmed Data : Inflammation. 2018 Oct 20. Epub 2018 Oct 20. PMID: 30343389
Article Published Date : Oct 19, 2018
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Thymoquinone reduces spinal cord injury by inhibiting inflammatory response, oxidative stress and apoptosis May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Jun ;15(6):4987-4994. Epub 2018 Apr 16. PMID: 29904397
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Spinal Cord Injuries
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Ursolic acid treatment alleviates diabetic kidney injury.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diabetes Metab Syndr Obes. 2019 ;12:2597-2608. Epub 2019 Dec 9. PMID: 31849504
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ursolic Acid
Diseases : Diabetes Mellitus: Type 2, Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Renoprotective
[+]

Allicin alleviated acrylamide-induced NLRP3 inflammasome activation.Jan 31, 2021

Pubmed Data : Food Chem Toxicol. 2021 Feb ;148:111937. Epub 2020 Dec 24. PMID: 33348049
Article Published Date : Jan 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Allicin
Diseases : Acrylamide-induced toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acrylamide
[+]

Coriolus versicolor alleviates diabetic cardiomyopathy by inhibiting cardiac fibrosis and NLRP3 inflammasome activation.Sep 30, 2019

Pubmed Data : Phytother Res. 2019 Oct ;33(10):2737-2748. Epub 2019 Jul 23. PMID: 31338905
Article Published Date : Sep 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Coriolus versicolor
Diseases : Cardiomyopathy, Diabetes: Cardiovascular Illness
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Curcumin significantly inhibited the production of pro-inflammatory cytokine IL-18 in E.coli LPS stimulated murine macrophage-like cells.Dec 31, 2014

Pubmed Data : Indian J Clin Biochem. 2015 Jan ;30(1):109-12. Epub 2014 Jul 15. PMID: 25646051
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation
Additional Keywords : Dose Response
[+]

Gamma-tocotrienol inhibits the NLRP3 inflammasome thereby delaying the progression of type 2 diabetes.Dec 31, 2015

Pubmed Data : J Lipid Res. 2016 Jan ;57(1):66-76. Epub 2015 Dec 1. PMID: 26628639
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin E: Gamma-tocotrienol
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation
[+]

Hydroxysafflor yellow A protects against myocardial ischemia/reperfusion injury.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:1170. Epub 2020 Jul 30. PMID: 32848777
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Safflower
Diseases : Inflammation, Myocardial Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hyperbaric oxygen therapy alleviates the inflammatory response in experimental traumatic brain injury.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Oct ;16(4):3922-3928. Epub 2017 Jul 24. PMID: 29067455
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : anti-inflammatory, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Inhibitory effects of hyperoside on lung cancer by inducing apoptosis and suppressing inflammatory response.Jul 31, 2016

Pubmed Data : Biomed Pharmacother. 2016 Aug ;82:216-25. Epub 2016 May 12. PMID: 27470358
Article Published Date : Jul 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Inflammation, Lung Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Juglone suppresses LPS-induced inflammatory responses and NLRP3 activation in macrophages.Jul 06, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Jul 7 ;25(13). Epub 2020 Jul 7. PMID: 32646056
Article Published Date : Jul 06, 2020
Study Type : In Vitro Study
Additional Links
Substances : Walnut
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Loganin's antioxidant effects prevent RSC96 Schwann cell pyroptosis by inhibiting ROS generation and suppressing NLRP3 inflammasome activation.Jan 22, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2020 08 23 ;9(9). Epub 2020 Aug 23. PMID: 32842536
Article Published Date : Jan 22, 2020
Study Type : In Vitro Study
Additional Links
Substances : Dogwood
Diseases : Diabetic Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Naringin may have a therapeutic effect on endothelial injury-related disorders.Mar 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biosci Rep. 2020 Mar 27 ;40(3). PMID: 32091090
Article Published Date : Mar 26, 2020
Study Type : In Vitro Study
Additional Links
Substances : Citrus naringin
Diseases : Atherosclerosis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Oridonin attenuates myocardial ischemia/reperfusion injury.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:7395187. Epub 2020 May 30. PMID: 32565873
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Oridonin
Diseases : Myocardial Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Resveratrol treatment in patients with polycystic ovary syndrome decreased pro-inflammatory and endoplasmic reticulum stress markers.Sep 03, 2019

Pubmed Data : Am J Reprod Immunol. 2019 Sep 4:e13186. Epub 2019 Sep 4. PMID: 31483910
Article Published Date : Sep 03, 2019
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Polycystic Ovary Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 Jun ;17(6):7939-7946. Epub 2018 Apr 5. PMID: 29620210
Article Published Date : May 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Saikosaponin
Diseases : Chemically-Induced Liver Damage, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Sweet olive flower ethanolic extract could be developed as an agent that suppresses IL-8 secretion to treat chronic inflammatory diseases.Jul 31, 2017

Pubmed Data : J Food Sci. 2017 Aug ;82(8):1792-1798. Epub 2017 Jul 3. PMID: 28671329
Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Olive
Diseases : Colon Cancer, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation
Additional Keywords : Plant Extracts
[+]

These results provide convincing evidence that α-lipoic acid might inhibit endometriosis progression.Jan 07, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Jan 8 ;26(2). Epub 2021 Jan 8. PMID: 33430114
Article Published Date : Jan 07, 2021
Study Type : In Vitro Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Endometriosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

This study shows the potential application of nobiletin in the treatment of non alcoholic fatty liver disease.Nov 30, 2018

Pubmed Data : Mol Med Rep. 2018 Dec ;18(6):5815-5822. Epub 2018 Oct 31. PMID: 30387829
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Nobiletin
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

This work supports berberine as a putative anti-tumor agent targeting glioma cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2019 ;9:364. Epub 2019 May 14. PMID: 31139563
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Glioma
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Interleukin-18 down-regulation, Interleukin-1 beta downregulation

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Connect with GreenMedInfo

MeWe

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.