Cyclooxygenase Inhibitors

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44 Substances Researched for Cyclooxygenase Inhibitors
NameACCKFocus
Omega-3 Fatty Acids313Locked
Pterostilbene211Locked
Pterocarpus marsupium110Locked
Curcumin78Locked
Resveratrol56Locked
Polyphenols24Locked
Stilbenes34Locked
Turmeric24Locked
Bacopa12Locked
Black Tea12Locked
Carrot12Locked
Fermented Foods and Beverages12Locked
Flavonoids12Locked
Flaxseed12Locked
Flowers12Locked
Gardenia12Locked
Lignans12Locked
Loquat Leaves12Locked
Mango 12Locked
Red Wine12Locked
Saffron12Locked
Sesamol12Locked
Soy12Locked
Soy: Fermented12Locked
White Mulberry 12Locked
Wogonin12Locked
Black Pepper11Locked
Butterbur11Locked
Cannabidiol 11Locked
Cannabinoids 11Locked
Dandelion 11Locked
Fish Oil11Locked
Guggul11Locked
Hyaluronic Acid11Locked
Maitake Mushroom11Locked
Melatonin11Locked
Mussel: Green-lipped (Perna canaliculus)11Locked
Plantago lanceolata11Locked
Plantago major11Locked
Polyunsaturated Fatty Acids (PUFAs)11Locked
Rose 11Locked
Rose Hips11Locked
Salicylic acid11Locked
Walnut11Locked

View the Evidence:
42 Abstracts with Cyclooxygenase Inhibitors Research

[+]

Omega-3 fatty acids may have therapeutic value in improving uterine artery blood flow in women with recurrent miscarriage.Jul 01, 2009

Pubmed Data : Fertil Steril. 2009 Jul;92(1):296-300. Epub 2008 Aug 9. PMID: 18692841
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Miscarriage
Pharmacological Actions : Cyclooxygenase Inhibitors
[+]

Pterocarpus marsupium extract exhibits anti-inflammatory activity in human subjects. May 01, 2005

Pubmed Data : Planta Med. 2005 May;71(5):387-92. PMID: 15931573
Article Published Date : May 01, 2005
Study Type : Human Study
Additional Links
Substances : Pterocarpus marsupium, Pterostilbene
Diseases : Inflammation
Pharmacological Actions : Cyclooxygenase Inhibitors, Postaglandin PGE2 downregulation
Additional Keywords : Plant Extracts, Stilbenes
[+]

A botanical extract of turmeric and white mulberry acted as a bradykinin receptor B1 and B2 antagonist.Dec 31, 2015

Pubmed Data : J Integr Med. 2016 Jan ;14(1):60-68. PMID: 26778230
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Turmeric, White Mulberry
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Cyclooxygenase Inhibitors, Lipoxygenase Inhibitors
Additional Keywords : Dose Response, Plant Extracts
[+]

An aqueous decoction of mango flowers has potential gastroprotective and ulcer-healing properties.Aug 01, 2004

Pubmed Data : Planta Med. 2004 Aug;70(8):745-52. PMID: 16500058
Article Published Date : Aug 01, 2004
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Flowers, Mango , Polyphenols
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Cyclooxygenase Inhibitors
Additional Keywords : Plant Extracts
[+]

Bacopa reduces inflammation by positively modulating COX and LOX enzyme pathways and Tumor Necrosis Factor.Jul 23, 2008

Pubmed Data : J Ethnopharmacol. 2008 Jul 23;118(2):305-11. Epub 2008 Apr 24. PMID: 18534796
Article Published Date : Jul 23, 2008
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Inflammation
Pharmacological Actions : Cyclooxygenase Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carrot seeds contain phytochemicals capable of inhibiting inflammatory enzymes.Jun 01, 2007

Pubmed Data : Carcinogenesis. 2007 Jun;28(6):1188-96. Epub 2006 Dec 6. PMID: 13680840
Article Published Date : Jun 01, 2007
Study Type : Animal Study
Additional Links
Substances : Carrot
Pharmacological Actions : Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Cherries contain anthocyanins which prevent lipid peroxidation and inhibit pro-inflammatory cycloxygenase enzymes.Feb 25, 2009

Pubmed Data : J Agric Food Chem. 2009 Feb 25;57(4):1239-46. PMID: 19199585
Article Published Date : Feb 25, 2009
Study Type : Animal Study
Additional Links
Diseases : Cholesterol: Oxidation, Inflammation, Oxidative Stress
Pharmacological Actions : Antioxidants, Cyclooxygenase Inhibitors
Additional Keywords : Plant Extracts
[+]

Crocin, a carotenoid fround within Gardenia jasminoides and Crocus sativus (Safron) has significant anti-inflammatory activity. Sep 23, 2009

Pubmed Data : J Agric Food Chem. 2009 Sep 23;57(18):8325-30. PMID: 19754168
Article Published Date : Sep 23, 2009
Study Type : Animal Study
Additional Links
Substances : Gardenia, Saffron
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Prostaglandin Antagonists
[+]

Curcumin has anti-thrombotic properties. Oct 01, 1999

Pubmed Data : Biochem Pharmacol. 1999 Oct 1;58(7):1167-72. PMID: 10484074
Article Published Date : Oct 01, 1999
Study Type : Animal Study
Additional Links
Substances : Curcumin, Turmeric
Diseases : Thrombosis
Pharmacological Actions : Anti-thrombotic, Cyclooxygenase Inhibitors, Platelet Aggregation Inhibitors, Thromboxane (TXB) Inhibitors
Additional Keywords : Plant Extracts
[+]

Dietary flaxseed may be chemopreventive for intestinal and colon tumor development in mice possibly by increasing omega -3 fatty acid levels, lignans, and decreasing COX-1 and COX-2 levels.Jan 01, 2009

Pubmed Data : Nutr Cancer. 2009;61(2):276-83. PMID: 19235044
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Flaxseed, Lignans, Omega-3 Fatty Acids
Diseases : Colon Cancer, Intestinal Cancer
Pharmacological Actions : Anticarcinogenic Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Fermented soybean has anti-inflammatory properties in the kidney of high-fat-fed rats.Jul 01, 1987

Pubmed Data : J Ethnopharmacol. 1987 Jul;20(2):85-106. PMID: 21332402
Article Published Date : Jul 01, 1987
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Soy, Soy: Fermented
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase Inhibitors, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Vascular Cell Adhesion Molecule-1 Inhibitor
[+]

Loquat leaves exhibit anti-inflammatory and pain-killing properties.Mar 24, 2011

Pubmed Data : J Ethnopharmacol. 2011 Mar 24;134(2):305-12. Epub 2010 Dec 21. PMID: 21182921
Article Published Date : Mar 24, 2011
Study Type : Animal Study
Additional Links
Substances : Loquat Leaves
Diseases : Inflammation, Pain
Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive , Cyclooxygenase Inhibitors, Interleukin-6 Downregulation, Nitric Oxide Enhancer, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Red wine and black tea and polyphenolic extracts modulate COX-2, iNOS and GSH-related gene expression in tumors, suggesting also a possible chemotherapeutic activity of these compounds.May 31, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr. 2002 Jun ;132(6):1376-9. PMID: 12042461
Article Published Date : May 31, 2002
Study Type : Animal Study
Additional Links
Substances : Black Tea, Polyphenols, Red Wine
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Chemotherapeutic, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Enzyme Inhibitors, Nitric Oxide Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Resveratrol, a compound found within grapes, prevents chemically-induced breast and skin cancer.Dec 28, 1984

Pubmed Data : Biochem Biophys Res Commun. 1984 Dec 28;125(3):996-1004. PMID: 8985016
Article Published Date : Dec 28, 1984
Study Type : Animal Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Breast Cancer, Inflammation, Skin Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antimutagenic Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase Inhibitors, Hydroperoxidase Inhibitor, Phase II Detoxification Enzyme Inducer
[+]

Sesamol attenuates diclofenac-induced acute gastric mucosal injury.Oct 01, 2008

Pubmed Data : Shock. 2008 Oct ;30(4):456-62. PMID: 18277948
Article Published Date : Oct 01, 2008
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Gastric Ulcer, Inflammation, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase Inhibitors, Gastroprotective
Problem Substances : Diclofenac
Adverse Pharmacological Actions : Irritant
[+]

Wogonin and 5-fluorouracil combination treatment caused a significant growth inhibition of human tumor xenografts in vivo.Jul 31, 2013

Pubmed Data : Biochem Cell Biol. 2013 Aug ;91(4):221-9. Epub 2013 Feb 14. PMID: 23859016
Article Published Date : Jul 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Chemosensitizer, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
Additional Keywords : Drug: 5-flourouracil, Natural Substance/Drug Synergy, Plant Extracts
[+]

An in-vitro test of cyclooxygenase-1 (COX-1) and 12-lipoxygenase (12-LOX) inhibition potency verified that both Plantago lanceolata and P. major exhibit considerable anti-inflammatory activity.Sep 05, 2010

Pubmed Data : J Pharm Biomed Anal. 2010 Sep 5 ;52(5):701-6. Epub 2010 Feb 18. PMID: 20219312
Article Published Date : Sep 05, 2010
Study Type : In Vitro Study
Additional Links
Substances : Plantago lanceolata, Plantago major
Diseases : Inflammation
Pharmacological Actions : 12-lipoxygenase (12-LOX), Anti-Inflammatory Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase Inhibitors
Additional Keywords : Plant Extracts
[+]

Butterbur (P. hybridus) exhibits ant-inflammatory activity in rat microglial (brain) cells. Jan 01, 2005

Pubmed Data : Planta Med. 2005 Jan;71(1):12-9. PMID: 15678367
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Butterbur
Diseases : Brain: Microglial Activation, Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Postaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

Cannabinoids have cyclooxygenase inhibitory properties.Jan 01, 2011

Pubmed Data : Biol Pharm Bull. 2011;34(5):774-8. PMID: 21532172
Article Published Date : Jan 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol, Cannabinoids
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase Inhibitors
[+]

Celecoxib and curcumin work synergistically to inhibit the growth of colorectal cancer cells.Sep 15, 2005

Pubmed Data : Clin Cancer Res. 2005 Sep 15;11(18):6738-44. PMID: 16166455
Article Published Date : Sep 15, 2005
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Colon Cancer, Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Prostaglandin PGE2 downregulation
Additional Keywords : Drug: Celecoxib, Drug Synergy
[+]

Clinical studies have reported that oral fish oil supplementation has beneficial effects in rheumatoid arthritis and among some asthmatics, supporting the idea that the n-3 FA in fish oil are anti-inflammatoryMar 31, 2003

Pubmed Data : Lipids. 2003 Apr ;38(4):343-52. PMID: 12848278
Article Published Date : Mar 31, 2003
Study Type : Review
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Asthma, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Curcumin exhibits anti-cancer, anti-inflammatory and antioxidant activities.Jul 01, 2000

Pubmed Data : Phytomedicine. 2000 Jul;7(4):303-8. PMID: 10969724
Article Published Date : Jul 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Breast Cancer, Colon Cancer, Kidney Cancer, Melanoma
Pharmacological Actions : Antioxidants, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Curcumin inhibits cyclooxygenase-2 expression in human colon cancer cells. Oct 30, 2001

Pubmed Data : Cancer Lett. 2001 Oct 30;172(2):111-8. PMID: 11566484
Article Published Date : Oct 30, 2001
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Chemopreventive, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Curcumin inhibits the growth of breast cancer through the manipulation of the arachidonate metabolism. Jan 01, 2007

Pubmed Data : BMC Cancer. 2007;7:138. Epub 2007 Jul 25. PMID: 17651499
Article Published Date : Jan 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Breast Cancer, Cancers: Drug Resistant
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase Inhibitors, Lipoxygenase Inhibitors
Additional Keywords : Drug: Doxorubicin
[+]

Curcumin prevents chemically-induced inflammation in gastrointestinal lines associated with cancer promotion.Feb 01, 2009

Pubmed Data : J Invest Dermatol. 2009 Feb;129(2):468-75. Epub 2008 Aug 14. PMID: 10190560
Article Published Date : Feb 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Cancers: All, Gastrointestinal Cancer, Inflammation
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Dandelion contains compounds with antioxidant and anti-inflammatory properties. Oct 01, 2004

Pubmed Data : Mol Cell Biochem. 2004 Oct;265(1-2):107-13. PMID: 15543940
Article Published Date : Oct 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
Additional Keywords : Plant Extracts
[+]

Green mussel lipid extracts have anti-cyclooxygenase activity superior to fish oil. Mar 01, 2007

Pubmed Data : Comp Biochem Physiol B Biochem Mol Biol. 2007 Mar;146(3):346-56. Epub 2006 Nov 17. PMID: 17197217
Article Published Date : Mar 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Fish Oil, Mussel: Green-lipped (Perna canaliculus)
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
Additional Keywords : Drug: Indomethacin, Green Muscle Lipids Superior to Fish Oil Lipids
[+]

Guggul inhibits inflammation by inhibiting lipid peroxidation and the Cox-1 and Cox-2 enzymes.Nov 01, 2004

Pubmed Data : Chem Biodivers. 2004 Nov;1(11):1842-53. PMID: 17191820
Article Published Date : Nov 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Guggul
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase Inhibitors
[+]

Hyaluronan inhibits prostaglandin E2 (inflammatory hormone) production in human macrophages.Jan 01, 2010

Pubmed Data : Tohoku J Exp Med. 2010;220(3):229-35. PMID: 20208419
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Hyaluronic Acid
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, NF-kappaB Inhibitor, Prostaglandin PGF2 downregulation
[+]

Inhibitory effects of black pepper (Piper nigrum) extracts and compounds on human tumor cell proliferation, cyclooxygenase enzymes, lipid peroxidation and nuclear transcription factor-kappa-B.Aug 01, 2010

Pubmed Data : Nat Prod Commun. 2010 Aug;5(8):1253-7. PMID: 20839630
Article Published Date : Aug 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Black Pepper
Diseases : Tumors
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Antiproliferative , Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Maitake contains cyclooxygenase inhibitory and antioxidant compounds. Nov 01, 2002

Pubmed Data : Endocr Pract. 2002 Nov-Dec;8(6):417-23. PMID: 12475274
Article Published Date : Nov 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Maitake Mushroom
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Melatonin with polyunsaturated fatty acids could exert a synergistic anti-tumor effect on a mammary gland adenocarcinoma.Mar 31, 2015

Pubmed Data : Nutrition. 2015 Apr ;31(4):570-7. Epub 2014 Jun 23. PMID: 25770319
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Melatonin, Polyunsaturated Fatty Acids (PUFAs), Walnut
Diseases : Breast Cancer
Pharmacological Actions : 12-lipoxygenase (12-LOX) Inhibitor, Apoptotic, Cyclooxygenase Inhibitors
Additional Keywords : Natural Substance Synergy
[+]

Multiple pathways are responsible for anti-inflammatory and cardiovascular activities of Hordeum vulgare L.Nov 25, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Transl Med. 2014 Nov 26 ;12:316. Epub 2014 Nov 26. PMID: 25428431
Article Published Date : Nov 25, 2014
Study Type : In Vitro Study
Additional Links
Substances : Barley
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardiovascular Agents, Cyclooxygenase Inhibitors, Lipoxygenase Inhibitors, Superoxide Dismutase Up-regulation
Additional Keywords : Plant Extracts
[+]

Oligonol has protective activity against oxidative stress-induced inflammation.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr Res Pract. 2015 Apr ;9(2):123-8. Epub 2014 Nov 1. PMID: 25861417
Article Published Date : Mar 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Lychee
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase Inhibitors, NF-kappaB Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase Inhibitors, Inflammation, Lychee, NF-kappaB Inhibitor, oxidative stress
[+]

Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity.Mar 01, 1987

Pubmed Data : Proc Natl Acad Sci U S A. 1987 Mar ;84(5):1417-20. PMID: 3103135
Article Published Date : Mar 01, 1987
Study Type : In Vitro Study
Additional Links
Substances : Salicylic acid
Diseases : Inflammation
Pharmacological Actions : Cyclooxygenase Inhibitors, Prostaglandin PGE2 downregulation
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Aspirin
[+]

Pterostilbene is equipotent to resveratrol in inhibiting inflammation, but may be more bioavailable due to its higher lipophilicity.Jun 01, 2008

Pubmed Data : Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S62-70. PMID: 18551458
Article Published Date : Jun 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene, Resveratrol
Diseases : Inflammation
Pharmacological Actions : Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, NF-kappaB Inhibitor, Proteasome Inhibitors
Additional Keywords : Stilbenes
[+]

Resveratrol has anti-inflammatory properties. Jul 15, 2010

Pubmed Data : Biochem J. 2010 Jul 15;429(2):273-82. PMID: 20450491
Article Published Date : Jul 15, 2010
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Inflammation
Pharmacological Actions : Anticarcinogenic Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
Additional Keywords : Stilbenes
[+]

Resveratrol inhibits PGHS-1 and upregulates PGHS-2 synthesis. Jun 01, 1998

Pubmed Data : Prostaglandins Other Lipid Mediat. 1998 Jun;56(2-3):131-43. PMID: 9785383
Article Published Date : Jun 01, 1998
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol, Stilbenes
Pharmacological Actions : Cyclooxygenase Inhibitors, Prostaglandin H Synthase-1 (PGHS-1) Inhibits, Prostaglandin H Synthase-2 (PGHS-2) Up-Regulation
Additional Keywords : Drug: Indomethacin
[+]

Review: Curcumin has potential value in the treatment of inflammatory bowel disease.Dec 01, 1997

Pubmed Data : J Lab Clin Med. 1997 Dec;130(6):576-84. PMID: 19519446
Article Published Date : Dec 01, 1997
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Inflammatory Bowel Diseases, Ulcerative Colitis
Pharmacological Actions : Cyclooxygenase Inhibitors, Interferon Gamma Reducer, Lipoxygenase Inhibitors, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Rosehip extract reduces inflammation by inhibiting cox-1 and cox-2 enzyme activity. Dec 01, 2007

Pubmed Data : Phytother Res. 2007 Dec;21(12):1251-2. PMID: 17639563
Article Published Date : Dec 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Rose , Rose Hips
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
[+]

Sensitization of colon cancer cell lines to butyrate-mediated proliferation inhibition by combined application of indomethacin and nordihydroguaiaretic acid.Dec 31, 2004

Pubmed Data : Cancer Detect Prev. 2005 ;29(3):276-85. Epub 2005 Feb 17. PMID: 15936596
Article Published Date : Dec 31, 2004
Study Type : In Vitro Study
Additional Links
Substances : Nordihydroguaiaretic acid (NDGA)
Diseases : Cancers: Drug Resistant, Colon Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Chemosensitizer, Cyclooxygenase Inhibitors
Additional Keywords : Natural Substance/Drug Synergy
[+]

Stilbenes such as resveratrol down-regulate inflammation in leukocytes.Apr 25, 1985

Pubmed Data : Biochim Biophys Acta. 1985 Apr 25;834(2):275-8. PMID: 3922423
Article Published Date : Apr 25, 1985
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol, Stilbenes
Diseases : Inflammation: Arachidonate Metabolism Associated, Inflammation: Leukocyte
Pharmacological Actions : 5-Hydroxyeicosatetraenoic acid (5-HETE) Inhibitor, 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase Inhibitors, Lipoxygenase Inhibitors, Thromboxane (TXB) Inhibitors, Thromboxane B2 Inhibitor

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