Chemosensitizer

Name	AC	CK
Curcumin	109	123
Ginsenosides	20	47
Resveratrol	32	37
EGCG (Epigallocatechin gallate)	22	31
Vitamin C	25	31
Quercetin	25	30
Melatonin	19	24
Genistein	15	22
Shikonin	17	21
Silibinin	7	21
Sulforaphane	17	20
Berberine	18	19
Flavonoids	16	19
Beta-Elemene	18	18
Emodin	14	18
Tanshinone IIA	17	18
Thymoquinone	11	17
Wogonin	10	17
Fucoidan	7	16
Pterostilbene	7	16
Ursolic Acid	9	13
Apigenin	11	12
Capsaicin	6	11
Vitamin D	9	11
Amurensin G	2	10
Caffeine	1	10
Catechin	5	10
Cucurbitacin B	7	10
Gingerol	4	10
Ginseng	2	10
Astragaloside	9	9
Bee Venom	9	9
Betulinic acid	7	9
Green Tea	4	9
Honokiol	9	9
Indole-3-Carbinol	6	9
Lotus	8	9
Artesunate	7	8
Bufalin	7	8
Gold (nanoparticles)	7	8
Luteolin	7	8
Nobiletin	7	8
Oridonin	6	8
Piperine	4	8
Piperlongumine	7	8
Polyphenols	8	8
Turmeric	4	8
Cannabidiol	5	7
Gynostemma	2	7
Naringenin	6	7
Panax Notoginseng	2	7
6-Shogaol	2	6
Demethoxycurcumin	5	6
Ellagic Acid	4	6
Fucoxanthin	6	6
Garlic	2	6
Hesperidin	4	6
Mistletoe	4	6
Parthenolide	6	6
Puerarin	4	6
Reishi Mushroom	4	6
Triptolide	6	6
Vitamin E	5	6
Antrodia camphorata	1	5
Astaxanthin	4	5
Carotenoids	4	5
Celastrol	4	5
Deguelin	4	5
Formononetin	3	5
Genipin	3	5
Ginger	4	5
Huaier (Trametes robiniophila murr)	1	5
Lycopene	3	5
Mangiferin	3	5
Panaxadiol	1	5
Phenethyl isothiocyanate	4	5
Vitamin E: Gamma-tocotrienol	5	5
White Mulberry	1	5
Xanthohumol	5	5
Bisdemethoxycurcumin	3	4
Cannabinoids	3	4
Chrysin	4	4
Crocin	4	4
Curcuminoids	3	4
DHA (Docosahexaenoic Acid)	4	4
Isoliquiritigenin	3	4
Kaempferol	3	4
Mulberry	4	4
Myricetin	4	4
Oleanolic acid	3	4
Oleuropein	3	4
Paprika	3	4
Phellinus Linteus	4	4
Pomegranate	3	4
Tocotrienol: Gamma	3	4
beta-Carotene	4	4
Arctigenin	3	3
Baicalein	2	3
Beta-Caryophyllene	2	3
Caffeic acid phenethyl ester	3	3
Cardamonin	2	3
Chrysanthemum Indicum	2	3
Curcumol	3	3
Dandelion	2	3
Delphinidin	2	3
Diosgenin	2	3
Eugenol	3	3
Isothiocyanates	2	3
Licorice	3	3
Lupeol	2	3
Red Clover	2	3
Rutin	3	3
Stilbenes	2	3
Tangeretin	3	3
Tea	2	3
Theaflavins	3	3
Tocotrienol: Delta	3	3
Tripterygium wilfordii	3	3
Vitamin K	3	3
Alpha-Lipoic Acid	2	2
Alpinia galanga	1	2
Anthocyanins	2	2
Apple	1	2
Artemisinin	2	2
Ashwagandha	2	2
Barberry	1	2
Berbamine	2	2
Biochanin A	2	2
Broccoli	1	2
Broccoli Sprouts	2	2
Bromelain	2	2
Cannabinoids: Synthetic	1	2
Chinese Skullcap	2	2
Cholesterol	1	2
Cinnamic acid	1	2
Crocetin	2	2
Dimethyl trisulfide (DMTS)	1	2
Echinacea	1	2
Fenugreek	1	2
Fisetin	2	2
Gallic Acid	2	2
Ginkgo biloba	2	2
Ginseng (Korean)	2	2
Grape	2	2
Isoflavones	1	2
Kahweol	2	2
Lemongrass	1	2
Lignans	2	2
Long Pepper	1	2
Lutein	2	2
Modified Arabinoxylan Rice Bran (MGN-3)	2	2
NAC (N-acetyl-L-cysteine)	2	2
Nettle	2	2
Nordihydroguaiaretic acid (NDGA)	2	2
Onion	1	2
Organosulfur Compounds	1	2
Paeonol	1	2
Pantothenic Acid (Vitamin B-5)	1	2
Phloretin	2	2
Piceatannol	1	2
Prunella vulgaris	1	2
Rosemaric Acid	2	2
Shiitake Mushroom	1	2
Soup	1	2
Soy	1	2
Sprouts	1	2
Sweet Orange	1	2
Urolithin A	1	2
Zeaxanthin	1	2
Acerola	1	1
Adlay	1	1
Allicin	1	1
Aloe Vera	1	1
Andrographis	1	1
Andrographolide	1	1
Antheraxanthin	1	1
Apple: Golden Delicious	1	1
Artichoke	1	1
Asiatic Acid	1	1
Bee Propolis	1	1
Beet	1	1
Beta Sitosterol	1	1
Bioflavonoids	1	1
Birch	1	1
Bloodroot	1	1
Burdock	1	1
Cafestol	1	1
Camptothecin	1	1
Canthaxanthin	1	1
Capsorubin	1	1
Carnosic Acid	1	1
Carnosine	1	1
Carnosol	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chlorogenic Acid	1	1
Citrus naringin	1	1
Cleistocalyx Operculatus	1	1
Coenzyme Q10	1	1
Cordyceps Militaris	1	1
Cranberry	1	1
Cucurbitacin D	1	1
Cyanidin	1	1
DIM (3,3'-diindolylmethane)	1	1
Damnacanthal	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Dopa bean	1	1
EPA (Eicosapentaenoic Acid)	1	1
Erucin	1	1
Farnesiferol A	1	1
Fennel	1	1
Fermented Foods and Beverages	1	1
Ferula Persica	1	1
Ferula Szowitsiana	1	1
Ferulic acid	1	1
Flavan-3-ols	1	1
Flaxseed	1	1
Flaxseed Oil	1	1
Folic Acid	1	1
Frankincense	1	1
Galbanic Acid	1	1
Geraniol	1	1
Ginseng (American)	1	1
Glucosamine	1	1
Grape Seed Extract	1	1
Guarana	1	1
Harmine	1	1
Hawthorn	1	1
Hedyotis corymbosa	1	1
Hedyotiscone A	1	1
Honey	1	1
Japanese Raisin Tree	1	1
Lactobacillus paracasei	1	1
Lactobacillus plantarum	1	1
Lactobacillus rhamnosus GG	1	1
Lactoferrin	1	1
Ligustrazine	1	1
Lion's Mane (Hericium Erinaceus)	1	1
Lobelia	1	1
Loquat	1	1
MSM (Methylsulfonylmethane)	1	1
Maca	1	1
Magnolol	1	1
Milk: Fermented	1	1
Nexrutine (Phellodendrom)	1	1
Nicotinamide	1	1
Oat Bran	1	1
Oleocanthal	1	1
Omega-3 Fatty Acids	1	1
Oolong tea	1	1
Orange	1	1
Paeoniflorin	1	1
Peony	1	1
Persimmon	1	1
Phyllanthus emblica	1	1
Poria cocos	1	1
Prickly Pear Cactus	1	1
Pycnogenol (Pine Bark)	1	1
Red Sage	1	1
Rhubarb	1	1
Riboflavin (Vitamin B-2)	1	1
Rice Bran	1	1
Rosemary	1	1
S-Adenosylmethionine (SAMe)	1	1
Saffron	1	1
Sakuranetin	1	1
Selenium	1	1
Silymarin	1	1
Stigmasterol	1	1
Tabebuia	1	1
Tannic Acid	1	1
Thyme	1	1
Tocotrienols	1	1
Vitamin A	1	1
Vitamin B-6	1	1
Vitamin E: alpha tocopherol	1	1
Vitamin K2	1	1
Vitex negundo	1	1
Vitexins	1	1
Wheat Grass	1	1
Zataria multiflora	1	1
Zinc	1	1
Zyflamend	1	1

[+]

The efficacy of ginsenoside Rg3 combined with first-line chemotherapy in the treatment of advanced non-small cell lung cancer. Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:630825. Epub 2021 Mar 18. PMID: 33815097

Article Published Date : Dec 31, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : Ginsenosides

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Angiogenesis Inhibitors, Chemoprotective Agents, Chemosensitizer

[+]

"Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer."Feb 28, 2011

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Pubmed Data : Expert Opin Ther Targets. 2016 Jan ;20(1):7-18. Epub 2015 Dec 15. PMID: 26568207

Article Published Date : Dec 31, 2015

Study Type : Animal Study, Human In Vitro

Additional Links

Diseases : Esophageal Cancer

Pharmacological Actions : Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK, Anti-metastatic, Apoptotic, Chemosensitizer

[+]

Silybin counteracts doxorubicin resistance by inhibiting GLUT1 expression.Dec 31, 2017

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Pubmed Data : Fitoterapia. 2018 Jan ;124:42-48. Epub 2017 Oct 12. PMID: 29031537

Article Published Date : Dec 31, 2017

Study Type : Human In Vitro

Additional Links

Substances : Silibinin

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Colon Cancer

Pharmacological Actions : Chemosensitizer, Glucose transporter-1 (GLUT1) expression down-regulation

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

The combination of centchroman with genistein has selective cytotoxic effect for human breast cancer cell lines.Oct 31, 2016

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Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice.Dec 31, 2015

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Pubmed Data : J Infect Chemother. 2016 Jan ;22(1):36-43. Epub 2015 Nov 19. PMID: 26603425

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[+]

Curcumin enhanced the therapeutic response to TMZ in U87MG glioblastoma by enhancing apoptosis.Sep 30, 2014

Curcumin is a potent chemosensitizer to improve the therapeutic index of paclitaxel.Jul 13, 2011

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Pubmed Data : Oncogene. 2011 Jul 14 ;30(28):3139-52. Epub 2011 Feb 14. PMID: 21317920

Article Published Date : Jul 13, 2011

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cervical Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer, NF-kappaB Inhibitor

Additional Keywords : Chemothapeutic Synergy: Paclitaxel

[+]

Curcumin may act synergistically with the chemotherapeutic regimen FOLFOX in gastric cancer in vitro and in vivo.Dec 31, 2015

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Pubmed Data : Oncol Res. 2016 ;23(1):29-34. PMID: 26802648

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Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:2951428. Epub 2019 Jul 17. PMID: 31391857

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Dandelion , Lemongrass

Diseases : Prostate Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy, Selective Cytotoxicity

[+]

Deguelin may represent a novel and effective chemo-agent against head and neck squamous cell carcinoma.Dec 31, 2012

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Pubmed Data : Oncotarget. 2016 Mar 29 ;7(13):16158-71. PMID: 26930714

Article Published Date : Mar 28, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Cancers: Drug Resistant, Colorectal Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer, MicroRNA modulator

Additional Keywords : Cancer Stem Cells, Chemothapeutic Synergy: 5-flourouracil

[+]

EGCG is a strong combination partner of gemcitabine reducing pancreatic cancer cell growth by suppressing glycolysis.Oct 04, 2019

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Pubmed Data : J Mater Chem B. 2020 May 15. Epub 2020 May 15. PMID: 32412025

Article Published Date : May 14, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Vitamin C

Pharmacological Actions : Chemosensitizer, Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin

[+]

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine.Apr 14, 2012

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Pubmed Data : Clin Cancer Res. 2012 Apr 15 ;18(8):2220-9. Epub 2012 Feb 20. PMID: 22351692

Article Published Date : Apr 14, 2012

Study Type : Animal Study

Additional Links

Substances : Tocotrienol: Gamma, Vitamin E

Diseases : Gastric Cancer

Pharmacological Actions : Anti-metastatic, Bcl-2 protein down-regulation, Chemosensitizer, Cyclin D1 Down-Regulation, Cyclooxygenase 2 Inhibitors, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor

Additional Keywords : Natural Substance/Drug Synergy

[+]

Formononetin regulates multiple oncogenic signalling cascades and enhances sensitivity to bortezomib in a multiple myeloma mouse model.Jul 06, 2019

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Pubmed Data : Oncol Lett. 2020 Dec ;20(6):374. Epub 2020 Oct 21. PMID: 33154772

Article Published Date : Nov 30, 2020

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Genipin

Diseases : Lung Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy

[+]

Genipin enhances the therapeutic effects of oxaliplatin by upregulating BIM in colorectal cancer.Feb 19, 2019

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Pubmed Data : Mol Cancer Ther. 2019 Feb 20. Epub 2019 Feb 20. PMID: 30787174

[+]

Mangiferin shows synergistic anticancer activity with cisplatin.Dec 31, 2017

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Oroxylin A increases the sensitivity of temozolomide on glioma cells by hypoxia-inducible factor 1α/hedgehog pathway under hypoxia.Jul 31, 2019

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Pubmed Data : J Cell Physiol. 2019 Aug ;234(10):17392-17404. Epub 2019 Feb 20. PMID: 30790292

Article Published Date : Jul 31, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Glioma

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Temozolomide

[+]

Paeonol reversed paclitaxel resistance in MCF-7/PTX cells by downregulating the activity of the SET/PP2A/Akt pathway.Jun 30, 2015

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Quercetin enhances the antitumor effect of trichostatin A and prevents its induced muscle wasting.Jan 01, 2018

Pubmed Data : Nutr Cancer. 2021 Jan 13:1-15. Epub 2021 Jan 13. PMID: 33439054

Article Published Date : Jan 12, 2021

Study Type : Animal Study

Additional Links

Substances : Sesamol

Diseases : Ehrlich carcinoma

Pharmacological Actions : Chemosensitizer

[+]

Shikonin enhances the chemotherapeutic sensitivity of gastric cancer cells to 5-fluorouracil and oxaliplatin.Nov 30, 2016

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[+]

The combination of TRAIL and cannabidiol decreased tumor growth in xenograft models.May 08, 2019

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Pubmed Data : Cancers (Basel). 2019 May 9 ;11(5). Epub 2019 May 9. PMID: 31075907

Article Published Date : May 08, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer

[+]

The discovery of IL-12-induced CB2 overexpression in thyroid cancer cells may offer a new target for anaplastic thyroid cancer treatmentJan 31, 2008

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Pubmed Data : Onco Targets Ther. 2019 ;12:5751-5765. Epub 2019 Jul 17. PMID: 31410021

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Oridonin

Diseases : Pancreatic Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

The study may shed light on the potential application of YH0618 as a novel medicinal food against chemotherapy-induced toxicity.Dec 31, 2018

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Pubmed Data : Biosci Rep. 2018 Dec 21 ;38(6). Epub 2018 Dec 11. PMID: 30420490

Article Published Date : Dec 20, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Cancers: Drug Resistant, Non-Small-Cell Lung Carcinoma

Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic

[+]

These results suggest that the combination of SK and gemcitabine may be a promising chemotherapy regimen for pancreatic cancer.Dec 31, 2016

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Pubmed Data : Am J Transl Res. 2017 ;9(12):5507-5517. Epub 2017 Dec 15. PMID: 29312502

Article Published Date : Dec 31, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Shikonin

Diseases : Pancreatic Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer, Chemotherapeutic

Additional Keywords : Chemotherapeutic Synergy: Gemcitabine

[+]

These results suggested that quercetin and cisplatin synergistically increased cellular toxicity in breast cancer cells.Jun 30, 2019

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Pubmed Data : J Ethnopharmacol. 2019 Oct 5 ;242:111699. Epub 2019 Apr 18. PMID: 31005632

Article Published Date : Oct 04, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Formononetin, Isoflavones

Diseases : Gliomas

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Temozolomide

[+]

This study highlights the potential therapeutic usefulness of curcumin as an adjunct in patients with chemoresistant advanced CRC. Feb 28, 2015

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Pubmed Data : Carcinogenesis. 2015 Mar ;36(3):355-67. Epub 2015 Feb 4. PMID: 25653233

3,3'-diindolylmethane enhances paclitaxel sensitivity in breast cancer. Dec 31, 2020

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Pubmed Data : Front Oncol. 2021 ;11:627856. Epub 2021 Jun 3. PMID: 34150611

Article Published Date : Dec 31, 2020

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemothapeutic Synergy: Paclitaxel

[+]

6-gingerol enhances the cisplatin sensitivity of gastric cancer cells.Feb 26, 2019

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Pubmed Data : Phytother Res. 2019 Feb 27. Epub 2019 Feb 27. PMID: 30811726

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Pubmed Data : Regul Toxicol Pharmacol. 2016 Sep 28. Epub 2016 Aug 28. PMID: 27693704

Article Published Date : Sep 27, 2016

Study Type : In Vitro Study

Additional Links

Substances : Astaxanthin

Diseases : Carcinoma: Non-Small-Cell Lung

Pharmacological Actions : Chemosensitizer

Additional Keywords : Natural Substance/Drug Synergy

[+]

A combination treatment of hyperbaric oxygen and doxorubicin synergistically inhibits H22 tumor growth, with a tumor inhibition rate of 91.5%.Jul 31, 2018

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Pubmed Data : Neuromolecular Med. 2020 Feb 21. Epub 2020 Feb 21. PMID: 32086739

Article Published Date : Feb 20, 2020

Study Type : In Vitro Study

Additional Links

Substances : Allicin

Diseases : Glioblastoma

Pharmacological Actions : Chemosensitizer, MicroRNA modulator

Additional Keywords : Chemotherapeutic Synergy: Temozolomide

[+]

Aloe-emodin enhances tamoxifen cytotoxicity in breast cancer cells.Feb 22, 2017

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Pubmed Data : Am J Chin Med. 2017 Feb 23:1-14. Epub 2017 Feb 23. PMID: 28231748

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Pubmed Data : Int J Oncol. 2017 Feb ;50(2):468-476. Epub 2017 Jan 2. PMID: 28101573

Article Published Date : Jan 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Flaxseed Oil

Diseases : Breast Cancer

Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin, Plant Extracts

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicines (Basel). 2018 Jun 20 ;5(2). Epub 2018 Jun 20. PMID: 29925764

Article Published Date : Jun 19, 2018

Study Type : In Vitro Study

Additional Links

Substances : Alpha-Lipoic Acid, Melatonin, Vitamin D

Diseases : Glioblastoma

Pharmacological Actions : Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Temozolomide

[+]

Anticancer and antimigration effects of a combinatorial treatment of 5-fluorouracil and Lactobacillus paracasei.Jun 05, 2018

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Pubmed Data : J Agric Food Chem. 2018 Jun 6 ;66(22):5549-5555. Epub 2018 May 22. PMID: 29737161

Article Published Date : Jun 05, 2018

Study Type : In Vitro Study

Additional Links

Substances : Lactobacillus paracasei, Milk: Fermented

Diseases : Colorectal Cancer

Pharmacological Actions : Antineoplastic Agents, Chemosensitizer, Chemotherapeutic

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

[+]

Application of curcumin and its derivatives in tumor multidrug resistance.Sep 30, 2020

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Pubmed Data : Phytother Res. 2020 Oct ;34(10):2438-2458. Epub 2020 Apr 7. PMID: 32255545

Article Published Date : Sep 30, 2020

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant

Pharmacological Actions : Chemosensitizer, Chemotherapeutic

Additional Keywords : Phytotherapy

[+]

Arctigenin enhances the cytotoxic effect of doxorubicin in MDA-MB-231 breast cancer cells.Apr 22, 2020

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Pubmed Data : J Pharm Pharmacol. 2017 Jun ;69(6):743-752. Epub 2017 Mar 7. PMID: 28266023

Article Published Date : Oct 26, 2015

Study Type : In Vitro Study

Additional Links

Substances : Berberine

Diseases : Lung Cancer

Pharmacological Actions : Chemosensitizer, STAT3 Inhibitor

Additional Keywords : Drug: Doxorubicin

[+]

Berberine is an effective method of increasing the sensitization of glioblastoma cells to temozolomide treatment.Dec 08, 2020

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Beta-elemene enhances susceptibility to cisplatin in resistant ovarian carcinoma cells.Aug 31, 2013

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Pubmed Data : Int J Oncol. 2013 Sep ;43(3):721-8. Epub 2013 Jun 28. PMID: 23817665

Article Published Date : Aug 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Beta-Elemene

Diseases : Cancers: Drug Resistant, Ovarian Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

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The efficacy of ginsenoside Rg3 combined with first-line chemotherapy in the treatment of advanced non-small cell lung cancer. Dec 31, 2019

"Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer."Feb 28, 2011

Caffeine potentiates chemotherapy for metastatic osteosarcoma.Sep 01, 2009

6-shogaol, 6-gingerol and pterostilbene selectively killed breast cancer stem cells.Mar 10, 2015

Amurensin G augmented the cytotoxic and apoptotic effects of TRAIL in TRAIL resistant leukemic cells.Jul 31, 2012

Amurensin G. was a potent SIRT1 Inhibitor which led to the down regulation of multidrug resistance.Oct 31, 2010

An ethanolic extract of T. camphoratus treatment further enhanced the tumor suppression efficiency of cisplatin and doxorubicin.Dec 31, 2014

Calebin A potentiates the effect of 5-FU and TNF-β against human colorectal cancer cells.Mar 30, 2020

Capsaicin inhibits 5-FU-induced autophagy and rendering Cholangiocarcinoma cells more susceptible to 5-FU-induced apoptosis.Dec 31, 2014

Epigenetic upregulation of metallothionein 2A by diallyl trisulfide enhances chemosensitivity of human gastric cancer cells to docetaxel.Jan 21, 2016

Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.Dec 23, 2016

Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells.Nov 03, 2016

Huaier may be a potential drug for the treatment of cancers caused by aberrant mTOR signaling.Mar 31, 2016

Melatonin in combination with sorafenib synergistically inhibits proliferation and induces apoptosis in human liver cancer cells.Feb 07, 2017

Morus alba flavonoid extract and doxorubicin induce a dose dependent cell death in HT-29 cell line.Mar 30, 2016

Panaxadiol and Epigallocatechin Gallate have a synergistic apoptotic effect on human colorectal cancer cells.May 08, 2012

Piperine enhanced mitomycin-C therapy in human cervical cancer cells.Nov 19, 2017

Pterostilbene might be used to modulate two anticancer compounds in well-defined sets of GBM patients.Nov 07, 2016

Silibinin may be a potentially useful therapeutic agent and chemosensitizer for esophageal cancer.Dec 31, 2015

Silybin counteracts doxorubicin resistance by inhibiting GLUT1 expression.Dec 31, 2017

The combination of centchroman with genistein has selective cytotoxic effect for human breast cancer cell lines.Oct 31, 2016

Thymoquinone intensified temozolomide-induced apoptosis in U87MG cells.Apr 20, 2017

Ursolic acid could affect the proliferation and apoptosis of human ovarian cancer stem-like cells and it is a potent anti-ovarian cancer agent.Oct 31, 2015

Wogonin could increase doxorubicin sensitivity in human breast cancer cells.Dec 31, 2014

This reports on the synergistic effects of vitamin C with sorafenib against liver cancers. May 31, 2016

Emodin reverses 5-Fu resistance in human colorectal cancer via downregulation of PI3K/Akt signaling pathway.Dec 31, 2019

"Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia."Jun 30, 2012

10-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models.Aug 05, 2020

20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.Dec 31, 2018

6-Gingerol is a potent inducer of p53 reactivation in HPV positive cervical cancer cells through proteasome inhibition.Nov 24, 2015

A combination therapy using silibinin and doxorubicin may show a better therapeutic efficacy in patients with HCC.Jun 30, 2016

A multiple-targets alkaloid nuciferine overcomes paclitaxel-induced drug resistance in vitro and in vivo.Sep 09, 2020

A variety of carotenoids induce reduce resistance to chemotherapy in multidrug resistant lymphoma and human breast cancer cell lines. Mar 01, 2004

Addition of bromelain and acetylcysteine to gemcitabine potentiates tumor inhibition in vivo in human colon cancer cell line LS174T.Dec 31, 2020

Adjuvant mistletoe therapy should be considered as an auspicious treatment option for glioma patients.Dec 31, 2017

An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer.Jun 04, 2017

Andrographolide sensitizes the cytotoxicity of human colorectal carcinoma cells toward cisplatin.Apr 30, 2014

Anti-cancer and cardioprotective effects of indol-3-carbinol in doxorubicin-treated mice.Dec 31, 2015

Anti-neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells.Dec 31, 2018

Antineoplaston A10 works synergistically with conventional chemotherapy in human liver cancer transplanted to animals.May 01, 1992

Apigenin could inhibit the growth of cisplatin-resistant colon cancer cells in vitro and in vivo.Feb 28, 2019

Artesunate promotes sensitivity to sorafenib in hepatocellular carcinoma.Oct 28, 2019

Ascorbate supplementation might help reduce the severe side effects that arise from BETi therapy by reducing the dosage necessary for treatment.Nov 26, 2017

Ascorbic acid chemosensitizes colorectal cancer cells and synergistically inhibits tumor growth.Dec 31, 2017

Astaxanthin inhibits gemcitabine-resistant human pancreatic cancer progressionOct 31, 2017

Baicalein reversed the resistance of human A549 lung adenocarcinoma cells to cisplatin.May 31, 2017

Berberine reverses breast cancer multidrug resistance.Apr 26, 2021

Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells.Apr 18, 2004

Betulinic acid chemosensitizes breast cancer cells.May 24, 2018

Bufalin could be an effective additional treatment to overcome acquired resistance to osimertinib in NSCLC cells.Sep 14, 2019

Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma.Jan 25, 2020

Celastrol enhances the antitumor activity of sorafenib in liver cancer cells.May 31, 2019

Cholesterol derived from LDL acts as a chemosensitizer in multidrug resistant lymphoblastic leukemia cells.Oct 01, 2007

Chrysanthemum indicum could enhance the anti-cancer activity of bleomycin and reduce the its induced pulmonary injury in H22 tumor-bearing mice.Feb 23, 2017

Cinnamic acid treatment increased the sensitivity of cancer stem cells to chemotherapeutic drugs through apoptosis.Dec 31, 2012

Co-treatments with Uro-A decreased IC50 values for both 5-FU and 5'DFUR and additionally arrested the cell cycle at the G2/M phase.Apr 30, 2015

Combination effects of ellagic acid with erlotinib in a Ba/F3 cell line expressing EGFR H773_V774 insH mutation.Dec 31, 2019

Combination of two or three components showed striking synergetic effect with gemcitabine in vitro.Jan 11, 2017

Combining ginger extract and doxorubicin revealed a greater efficacy as anticancer therapeutic regimen.Feb 21, 2017

Cucurbitacin B and cisplatin combination treatment may be a potentially useful therapeutic option for individuals diagnosed with laryngeal cancer.Aug 31, 2010

Cucurbitacin B inhibits gastric cancer progression by suppressing STAT3 activity.Feb 19, 2020

Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.Sep 13, 2010

Curcumin and vitamin D3 enhanced the tumor response to paclitaxel.Oct 15, 2019

Curcumin combined with 5-FU led to the lower cell viability and higher apoptosis than 5-FU treated alone.Sep 30, 2012

Curcumin enhanced the therapeutic response to TMZ in U87MG glioblastoma by enhancing apoptosis.Sep 30, 2014

Curcumin enhances adriamycin-induced human liver-derived hepatoma G2 cell death.Jun 14, 2011

Curcumin enhances the effect of cisplatin in suppression of head and neck squamous cell carcinoma. Oct 01, 2010

Curcumin has a synergistic effect with cisplatin against fibrosarcoma.Mar 01, 1999

Curcumin has anticancer, chemosensitization and radiosensitization effects in prostate cancer.Mar 01, 2007

Curcumin inhibited growth of murine malignant pleural mesothelioma cell-derived tumors in vivo in part by stimulating apoptosis.Oct 31, 2011

Curcumin is a potent chemosensitizer to improve the therapeutic index of paclitaxel.Jul 13, 2011

Curcumin may act synergistically with the chemotherapeutic regimen FOLFOX in gastric cancer in vitro and in vivo.Dec 31, 2015

Chemosensitizer

View the Evidence:
902 Abstracts with Chemosensitizer Research