Autophagy Up-regulation

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112 Substances Researched for Autophagy Up-regulation
NameACCKFocus
Resveratrol1120Locked
EGCG (Epigallocatechin gallate)615Locked
Honokiol915Locked
Ginsenosides913Locked
Tanshinone IIA912Locked
Curcumin67Locked
Delta-tetrahydrocannabinol (THC)37Locked
Isoliquiritigenin27Locked
Lotus 77Locked
Maitake Mushroom27Locked
Silibinin37Locked
Vitamin C27Locked
Berberine36Locked
Dandelion 26Locked
Parthenolide56Locked
Allicin35Locked
Cannabidiol45Locked
Cannabinoids 45Locked
Orange: Mandarin15Locked
6-Shogaol34Locked
Bisdemethoxycurcumin34Locked
Cucurbitacin B 34Locked
Puerarin34Locked
Spermidine 34Locked
Anthocyanins23Locked
Baicalein23Locked
Chrysin33Locked
Cranberry Proanthocyanidins23Locked
Curcuminoids23Locked
Genipin23Locked
Huaier (Trametes robiniophila murr)23Locked
Lychee23Locked
Oleanolic acid23Locked
Oleuropein23Locked
Olive Oil23Locked
Quercetin33Locked
Shikonin23Locked
Aduki bean12Locked
Allspice12Locked
Aloe Vera22Locked
Astragaloside22Locked
Bitter Melon22Locked
Cannabis22Locked
Carnitine12Locked
Cherry: All Varieties12Locked
Coenzyme Q1012Locked
Cranberry12Locked
Crocin12Locked
D-Limonene12Locked
Demethoxycurcumin12Locked
Emodin22Locked
Fisetin22Locked
Ginger12Locked
Gingerol 12Locked
Hydroxytyrosol12Locked
Luteolin12Locked
Mangosteen12Locked
Medicinal Mushrooms12Locked
Melatonin12Locked
Paeoniflorin22Locked
Palmitoylethanolamide 12Locked
Peanut12Locked
Piperlongumine 22Locked
Probiotics12Locked
Pterostilbene22Locked
Stilbenes22Locked
Sweet Potato: Purple12Locked
Thymoquinone22Locked
Ursolic Acid22Locked
Wogonin22Locked
18β-Glycyrrhetinic Acid11Locked
Alpha-Lipoic Acid11Locked
Bacopa11Locked
Bee Propolis11Locked
Bee Venom11Locked
Bergamot11Locked
Betulinic acid11Locked
Bromelain11Locked
Caffeic acid phenethyl ester11Locked
Camel Milk 11Locked
Carnosol11Locked
Chlorophyllin11Locked
Cucurbitacin E 11Locked
Diosmin 11Locked
Fenugreek11Locked
Fucoidan11Locked
Fucoxanthin 11Locked
Helenalin11Locked
Hibiscus sabdariffa 11Locked
Hu Zhang (Polygonum cuspidatum)11Locked
Indole-3-Carbinol11Locked
Kaempferol11Locked
Licorice11Locked
Long Pepper11Locked
Lutein11Locked
Magnolol11Locked
Mushrooms: All 11Locked
Oridonin11Locked
Phellinus Linteus11Locked
Phenethyl isothiocyanate11Locked
Pineapple11Locked
Pumpkin Seeds11Locked
Sesamin11Locked
Sulforaphane11Locked
Syrian rue11Locked
Tocotrienol: Delta11Locked
Tocotrienol: Gamma11Locked
Urolithin A 11Locked
Vitamin E: Gamma-tocotrienol11Locked
Walnut11Locked
Wasabi11Locked
Zerumbone11Locked

View the Evidence:
349 Abstracts with Autophagy Up-regulation Research

[+]

silibinin induced autophagic cell death through ROS-dependent mitochondrial dysfunction and ATP depletion involving BNIP3 in MCF7 cells. May 31, 2015

Pubmed Data : Oncol Rep. 2015 Jun ;33(6):2711-8. Epub 2015 Apr 17. PMID: 25891311
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Silibinin
Diseases : Breast Cancer
Pharmacological Actions : Autophagy Up-regulation, Bcl-2 protein down-regulation
[+]

Sinensetin may be a potential anti-cancer agent targeting autophagic cell death in human liver cancer.Aug 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Aug 15 ;12(8). Epub 2020 Aug 15. PMID: 32824273
Article Published Date : Aug 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Spermidine and resveratrol mediates pharmacological lifespan extension through the up-regulation of autophagy.Dec 01, 2009

Pubmed Data : Aging (Albany NY). 2009 Dec;1(12):961-70. Epub 2009 Dec 23. PMID: 20157579
Article Published Date : Dec 01, 2009
Study Type : Review
Additional Links
Substances : Resveratrol, Spermidine
Diseases : Aging
Pharmacological Actions : Autophagy Up-regulation, Histone deacetylase inhibitor
Additional Keywords : Stilbenes
[+]

Spermidine is a novel autophagy inducer and longevity elixir.Jan 01, 2010

Pubmed Data : Autophagy. 2010 Jan;6(1):160-2. PMID: 20110777
Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Substances : Spermidine
Diseases : Aging
Pharmacological Actions : Autophagy Up-regulation
[+]

Supplementation of diet with extra virgin olive oil might have potential benefits for Alzheimer's patients.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:5010741. Epub 2018 Feb 20. PMID: 29675133
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Oleuropein, Olive Oil
Diseases : Alzheimer's Disease
Pharmacological Actions : Autophagy Up-regulation, Neuroprotective Agents
[+]

T. pratense showed anti-cancer properties via induction of apoptosis and autophagy cell death.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell J. 2018 Oct ;20(3):412-421. Epub 2018 May 15. PMID: 29845796
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Red Clover
Diseases : Glioblastoma Multiforme
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation
Additional Keywords : Chemotherapeutic Synergy: Temozolomide
[+]

Tanshinone IIA activates autophagy to reduce liver ischemia-reperfusion injury.Dec 31, 2017

Pubmed Data : Pharmazie. 2018 07 1 ;73(7):396-401. PMID: 30001774
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Liver Injury: Ischemia/reperfusion
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Autophagy Up-regulation, Hepatoprotective
[+]

Tanshinone IIA ameliorates oxaliplatin-induced neurotoxicity via mitochondrial protection and autophagy promotion.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(5):3140-3149. Epub 2019 May 15. PMID: 31217883
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Chemotherapy-Induced Toxicity: Oxaliplatin
Pharmacological Actions : Autophagy Up-regulation, Chemoprotective Agents, Neuroprotective Agents
[+]

Tanshinone IIA could suppress the viability of U251 cells and induce cell apoptosis and autophagy.Dec 31, 2016

Pubmed Data : Pharmacology. 2017 ;99(3-4):188-195. Epub 2016 Nov 26. PMID: 27889779
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Glioma
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation
[+]

Tanshinone IIA induces apoptosis and autophagy in acute monocytic leukemia.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(5):2995-3006. Epub 2019 May 15. PMID: 31217869
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Tanshinone IIA induces autophagic cell death in KBM-5 leukemia cells.Feb 28, 2014

Pubmed Data : Phytother Res. 2014 Mar ;28(3):458-64. Epub 2013 Jun 27. PMID: 23813779
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Tanshinone IIA induces cell death via Beclin‐1‐dependent autophagy in oral squamous cell carcinoma SCC‐9 cell line.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Med. 2018 02 ;7(2):397-407. Epub 2018 Jan 6. PMID: 29316373
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Squamous cell carcinoma
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Tanshinone IIA sensitizes oral squamous cell carcinoma to radiation due to an enhanced autophagy.Aug 31, 2016

Pubmed Data : Environ Toxicol Pharmacol. 2016 Sep ;46:264-269. Epub 2016 Jul 30. PMID: 27521571
Article Published Date : Aug 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Oral Cancer, Squamous cell carcinoma
Pharmacological Actions : Apoptotic, Autophagy Up-regulation, Radiosensitizer
[+]

The Anti-cancer effect of quercetin: Molecular implications in cancer metabolism.Jun 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Jun 28 ;20(13). Epub 2019 Jun 28. PMID: 31261749
Article Published Date : Jun 27, 2019
Study Type : Review
Additional Links
Substances : Quercetin
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation, Wnt/β-catenin signaling pathway modulation
[+]

The anti-tumour effect of melittin and its role in autophagy in human hepatocellular carcinoma cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(2):931-941. Epub 2019 Feb 15. PMID: 30899392
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Bee Venom
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

The anticancer properties of silibinin: its molecular mechanism and therapeutic effect in breast cancer.Dec 19, 2019

Pubmed Data : Anticancer Agents Med Chem. 2019 Dec 20. Epub 2019 Dec 20. PMID: 31858905
Article Published Date : Dec 19, 2019
Study Type : Review
Additional Links
Substances : Silibinin
Diseases : Breast Cancer
Pharmacological Actions : Anti-metastatic, Apoptotic, Autophagy Up-regulation, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Carboplatin, Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin
[+]

The combination treatment of cisplatin and resveratrol synergistically induced apoptosis in malignant mesothelioma cells. Aug 30, 2016

Pubmed Data : Food Chem Toxicol. 2016 Aug 31 ;97:96-107. Epub 2016 Aug 31. PMID: 27591926
Article Published Date : Aug 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Mesothelioma
Pharmacological Actions : Apoptotic, Autophagy Up-regulation, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

The findings demonstrated that licochalcone A inhibited the proliferation, migration, invasion, and induced autophagy.Aug 31, 2018

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2018 Sep ;43(17):3545-3552. PMID: 30347925
Article Published Date : Aug 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Licorice
Diseases : Kidney Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Autophagy Up-regulation
[+]

The findings of this study indicated that luteolin effectively enhanced TRAIL initiated apoptosis.Jan 31, 2019

Pubmed Data : Int J Oncol. 2019 Feb ;54(2):665-672. Epub 2018 Nov 14. PMID: 30431076
Article Published Date : Jan 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Luteolin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation, Chemosensitizer
[+]

The induction of autophagy may promotes longevity.Sep 01, 2010

Pubmed Data : Nat Cell Biol. 2010 Sep;12(9):842-6. PMID: 20811357
Article Published Date : Sep 01, 2010
Study Type : Review
Additional Links
Diseases : Aging
Pharmacological Actions : Autophagy Up-regulation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Stilbenes
[+]

The interplay between autophagy and apoptosis induced by tanshinone IIA in prostate cancer cells.May 31, 2016

Pubmed Data : Tumour Biol. 2016 Jun ;37(6):7667-74. Epub 2015 Dec 21. PMID: 26687918
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Tanshinone IIA
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

The present study suggests that betulinic acid has anti-hepatic fibrosis activity.Dec 31, 2018

Pubmed Data : J Nat Med. 2019 Jan ;73(1):179-189. Epub 2018 Oct 30. PMID: 30377904
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Liver Fibrosis
Pharmacological Actions : Autophagy Up-regulation, Hepatoprotective
[+]

There exists solid scientific evidence supporting that cannabinoids exhibit a remarkable anticancer activity in preclinical models of cancer.Jan 03, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 4 ;64:259-66. Epub 2015 Jun 10. PMID: 26071989
Article Published Date : Jan 03, 2016
Study Type : Review
Additional Links
Substances : Cannabinoids , Cannabis
Diseases : Cancers: All
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

These experiments provide additional mechanistic insight regarding C-PAC induced cancer cell death through modulation of ROS.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Berry Res. 2016;6(2):125-136. PMID: 27583064
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cranberry Proanthocyanidins
Diseases : Esophageal Cancer
Pharmacological Actions : Autophagy Up-regulation
[+]

These finding provide the basis for therapeutic potential of O. majorana in the treatment of colon cancer.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2019 ;9:795. Epub 2019 Aug 21. PMID: 31497536
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Marjoram
Diseases : Colorectal Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

These findings provided direct evidence that Bisdemethoxycurcumin inhibits 95D-cell migration and invasion.Oct 31, 2015

Pubmed Data : Mol Med Rep. 2015 Nov ;12(5):7603-8. Epub 2015 Sep 24. PMID: 26459909
Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Bisdemethoxycurcumin
Diseases : Lung Cancer: Metastatic
Pharmacological Actions : Anti-metastatic, Antiproliferative , Autophagy Up-regulation
[+]

These findings support 6-shogaol's clinical promise as a potential candidate for HCC therapyJun 19, 2015

Pubmed Data : Eur J Pharmacol. 2015 Jun 20 ;762:449-458. Epub 2015 Jun 20. PMID: 26101062
Article Published Date : Jun 19, 2015
Study Type : In Vitro Study
Additional Links
Substances : 6-Shogaol
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation, Cell cycle arrest
[+]

These findings thus provide new information about the potential link between autophagy and metastasis inhibition induced by silibinin.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2015 ;16(4):8415-29. Epub 2015 Apr 15. PMID: 25884331
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Kidney Cancer
Pharmacological Actions : Anti-metastatic, Autophagy Up-regulation
[+]

These findings unveil a novel mechanism of drug action by parthenolide in osteosarcoma cancer cells.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2016 ;40(1-2):146-154. Epub 2016 Nov 18. PMID: 27855364
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Parthenolide
Diseases : Osteosarcoma
Pharmacological Actions : Antioxidants, Autophagy Up-regulation, Cytotoxic, NF-kappaB Inhibitor
[+]

These results suggest that dietary consumption of urolithin A could induce autophagy and inhibit human colorectal cancer cell metastasis.Jan 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Carcinog. 2018 Feb ;57(2):193-200. Epub 2017 Nov 26. PMID: 28976622
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Urolithin A
Diseases : Colorectal Cancer
Pharmacological Actions : Anti-metastatic, Autophagy Up-regulation
[+]

This review demonstrates the several biological activities of oleuropein including antioxidant, anti-inflammatory and anticancer properties.Nov 21, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2019 Nov 22 ;8(12). Epub 2019 Nov 22. PMID: 31766676
Article Published Date : Nov 21, 2019
Study Type : Review
Additional Links
Substances : Oleuropein
Diseases : Atherosclerosis, Cancers: All, Cardiovascular Diseases, Chronic Kidney Disease (CKD), Colitis, Diabetes Mellitus: Type 2, Hypertension, Inflammation, Neurodegenerative Diseases, Oxidative Stress, Pleurisy
Pharmacological Actions : Anti-Inflammatory Agents, Antihypertensive Agents, Antioxidants, Autophagy Up-regulation, Cardioprotective, Neuroprotective Agents, Nrf2 activation
[+]

This review will center on mechanisms by which CBD, and other plant-derived cannabinoids inefficient at activating cannabinoid receptors, inhibit tumor cell viability, invasion, metastasis, angiogenesis.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroimmune Pharmacol. 2015 Jun ;10(2):255-67. Epub 2015 Apr 28. PMID: 25916739
Article Published Date : May 31, 2015
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antiproliferative , Apoptotic, Autophagy Up-regulation
Additional Keywords : Cancer Stem Cells
[+]

This reviews the current literature on the role of natural products in ovarian cancer chemoprevention.Dec 27, 2017

Pubmed Data : Cancer Lett. 2017 Dec 28 ;411:191-200. Epub 2017 Oct 7. PMID: 29017913
Article Published Date : Dec 27, 2017
Study Type : Review
Additional Links
Substances : Curcumin, EGCG (Epigallocatechin gallate), Resveratrol, Sulforaphane
Diseases : Ovarian Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Apoptotic, Autophagy Up-regulation, Chemopreventive
Additional Keywords : Cancer Stem Cells
[+]

This study sheds new light on the mechanisms underlying the activity of Huaier against prostate cancer.May 31, 2018

Pubmed Data : Oncol Rep. 2018 Jun ;39(6):3055-3063. Epub 2018 Apr 5. PMID: 29658595
Article Published Date : May 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Huaier (Trametes robiniophila murr)
Diseases : Prostate Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Autophagy Up-regulation
[+]

This suggested that Poria cocos Wolf can be potentially used for the treatment of hepatic steatosis.Sep 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Sep 27 ;20(19). Epub 2019 Sep 27. PMID: 31569635
Article Published Date : Sep 26, 2019
Study Type : In Vitro Study
Additional Links
Substances : Poria cocos
Diseases : Hepatic Steatosis
Pharmacological Actions : Autophagy Up-regulation, Hepatoprotective, Hypolipidemic
[+]

Thymoquinone exhibits anticancer activity via numerous mechanisms of action.Apr 17, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Apr 18. Epub 2017 Apr 18. PMID: 28489566
Article Published Date : Apr 17, 2017
Study Type : Review
Additional Links
Substances : Thymoquinone
Diseases : Cancers: All
Pharmacological Actions : Anti-metastatic, Antioxidants, Antiproliferative , Apoptotic, Autophagy Up-regulation, Immunomodulatory
[+]

Thymoquinone inhibits the metastasis of renal cell cancer cells.Nov 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Sci. 2018 Dec ;109(12):3865-3873. Epub 2018 Oct 28. PMID: 30259603
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Kidney Cancer
Pharmacological Actions : Anti-metastatic, Autophagy Up-regulation
[+]

Total ginsenosides extract induce autophagic cell death in NSCLC cells through activation of endoplasmic reticulum stress.Jul 16, 2019

Pubmed Data : J Ethnopharmacol. 2019 Jul 17 ;243:112093. Epub 2019 Jul 17. PMID: 31325602
Article Published Date : Jul 16, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Upregulation of autophagy by ginsenoside Rg2 in MCF-7 cells.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anim Cells Syst (Seoul). 2018 ;22(6):382-389. Epub 2018 Nov 19. PMID: 30533260
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Breast Cancer
Pharmacological Actions : Autophagy Up-regulation
[+]

Urolithin A protects pancreatic β Cells from apoptosis by activating autophagy.Nov 23, 2020

Pubmed Data : J Ethnopharmacol. 2020 Nov 24:113628. Epub 2020 Nov 24. PMID: 33246115
Article Published Date : Nov 23, 2020
Study Type : In Vitro Study
Additional Links
Substances : Urolithin A
Pharmacological Actions : Anti-Apoptotic, Autophagy Up-regulation, Pancreato Protective Agents
[+]

Ursolic acid at low micromolar range may promote its anticancer action by targeting glycolysis in phenotypically distinct breast cancer cells.Feb 16, 2017

Pubmed Data : Apoptosis. 2017 Feb 17. Epub 2017 Feb 17. PMID: 28213701
Article Published Date : Feb 16, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ursolic Acid
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Ursolic acid induces apoptosis and autophagy in oral cancer cells.May 06, 2019

Pubmed Data : Environ Toxicol. 2019 May 7. Epub 2019 May 7. PMID: 31062913
Article Published Date : May 06, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ursolic Acid
Diseases : Oral Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
[+]

Ursolic acid is a potential anti-inflammatory natural compound for treating acute kidney injury by inducing autophagy.Jul 10, 2019

Pubmed Data : Cytokine. 2019 Jul 11 ;123:154726. Epub 2019 Jul 11. PMID: 31302461
Article Published Date : Jul 10, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ursolic Acid
Diseases : Kidney Damage
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitamin C affects G0/G1 cell cycle and autophagy by downregulating of cyclin D1 in gastric carcinoma cells.Feb 23, 2021

Pubmed Data : Biosci Biotechnol Biochem. 2021 Feb 24 ;85(3):553-561. PMID: 33624781
Article Published Date : Feb 23, 2021
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Autophagy Up-regulation, Cell cycle arrest, Cyclin D1 Down-Regulation
[+]

Walnut-derived peptides regulated oxidative stress by promoting autophagy in the Aβ25-35-induced PC12 cells.Feb 21, 2020

Pubmed Data : J Agric Food Chem. 2020 Feb 22. Epub 2020 Feb 22. PMID: 32090563
Article Published Date : Feb 21, 2020
Study Type : In Vitro Study
Additional Links
Substances : Walnut
Diseases : Alzheimer's Disease, Brain: Oxidative Stress
Pharmacological Actions : Autophagy Up-regulation, Neuroprotective Agents
[+]

Withaferin A alleviates fulminant hepatitis by targeting macrophage and NLRP3.Feb 10, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Dis. 2021 Feb 11 ;12(2):174. Epub 2021 Feb 11. PMID: 33574236
Article Published Date : Feb 10, 2021
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha
Diseases : Hepatitis
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Hepatoprotective
[+]

Wogonin induces Beclin-1/PI3K and reactive oxygen species-mediated autophagy in human pancreatic cancer cells.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2016 Dec ;12(6):5059-5067. Epub 2016 Nov 8. PMID: 28105213
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Autophagy Up-regulation
[+]

Zerumbone induces apoptosis and autophagy in human hormone-refractory prostate cancers.Oct 31, 2015

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov ;388(11):1223-36. Epub 2015 Aug 6. PMID: 26246051
Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Zerumbone
Diseases : Prostate Cancer
Pharmacological Actions : Apoptotic, Autophagy Up-regulation, Cell cycle arrest
[+]

β-elemene reverses the resistance of p53-deficient colorectal cancer cells to 5-fluorouracil.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Bioeng Biotechnol. 2020 ;8:378. Epub 2020 May 8. PMID: 32457882
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Beta-Elemene
Diseases : Colorectal Cancer
Pharmacological Actions : Autophagy Up-regulation, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil

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