Antidepressive Agents

Name	AC	CK
Saffron	13	128
Vitamin D	13	114
Curcumin	19	109
Psilocybin	17	107
Probiotics	20	100
Omega-3 Fatty Acids	10	84
Ayahuasca	15	80
Fruit: All	6	60
Vegetables: All	6	60
Magnesium	6	53
DHA (Docosahexaenoic Acid)	4	50
EPA (Eicosapentaenoic Acid)	4	50
St. Johns Wort	5	42
Lavender: Essential Oil	3	40
St. John's Wort	3	40
Melatonin	7	38
Coenzyme Q10	5	34
Rhodiola (Tibetan Ginseng)	4	32
Homeopathic Medicine: All	3	30
Flavonoids	6	27
Ginsenosides	14	27
Chamomile	4	23
NAC (N-acetyl-L-cysteine)	3	22
Docosahexaenoic acid (DHA)	2	21
Chlorella (Algae)	2	20
Dehydroepiandrosterone (DHEA)	1	20
Eicosapentaenoic acid (EPA)	1	20
Fiber	2	20
Fish	2	20
Ginkgo biloba	1	20
Inositol	1	20
Lemon Balm	2	20
Riboflavin (Vitamin B-2)	2	20
SAMe (S-adenosylmethionine)	1	20
Soy	2	20
Vitamin B-12	2	20
Vitamin B-6	2	20
Cannabidiol	10	19
Anise	3	14
Bifidobacterium Longum	3	14
Green Tea	3	14
Palmitoylethanolamide	4	14
Rose	4	14
Delta-tetrahydrocannabinol (THC)	3	13
Ashwagandha	2	12
Coffee	2	12
Dandelion	2	12
Fish Oil	2	12
Piperidines	2	12
Theanine	2	12
Bacopa	6	11
Paeoniflorin	6	11
S-Adenosylmethionine (SAMe)	2	11
Bifidobacterium Bifidum	1	10
Blueberry	1	10
Caffeine	1	10
Carotenoids	1	10
Crocin	1	10
Cysteine (see N-Acetylcysteine)	1	10
DHEA (Dehydroepiandrosterone)	1	10
Fennel	1	10
Green Leafy Vegetables	1	10
Hops	1	10
Kava Kava	1	10
Lactobacillus casei	1	10
Lactobacillus rhamnosus	1	10
Lavender	1	10
Maca	1	10
Motherwort	1	10
Mushrooms: All	1	10
Nuts	1	10
Piperine	5	10
Potatoes	1	10
Psychedelics:All	6	10
Seaweed	1	10
Selenium	1	10
Tryptophan	1	10
Vitamin B-3 (Niacin)	1	10
Vitamin B-5 (Pantothenic Acid)	1	10
Vitamin E	1	10
Walnut	1	10
Ferulic acid	4	8
Hesperidin	4	8
Perillaldehyde	4	8
Lysergic Acid Diethylamide (LSD)	6	7
Resveratrol	4	7
Banana	3	6
Berberine	3	6
Chrysin	3	6
Gastrodin	3	6
Magnolol	3	6
Rosemary	3	6
Silymarin	3	6
Vitamin C	3	6
Cannabinoids	3	5
Fenugreek	3	5
Valerian	3	5
Asparagus	2	4
Bifidobacterium	2	4
Chlorogenic Acid	2	4
Coconut Husk/Fiber	2	4
Flaxseed	2	4
Gardenia	2	4
Genipin	2	4
Lactobacillus helveticus	2	4
Lion's Mane (Hericium Erinaceus)	2	4
Luteolin	2	4
Musk (Animal)	2	4
Naringenin	2	4
Nettle	2	4
Pomegranate	2	4
Salvia divinorum	3	4
Silibinin	2	4
Sulforaphane	2	4
Bael	2	3
Corn Silk	2	3
Kratom	3	3
Panax Notoginseng	2	3
Passion Flower	2	3
Perilla	2	3
Polyphenols	2	3
Polyunsaturated Fatty Acids (PUFAs)	2	3
Allicin	1	2
Angelica	1	2
Apigenin	1	2
Arctigenin	1	2
Arginine	1	2
Asiatic Acid	1	2
Astaxanthin	1	2
Astragaloside	1	2
Bai Zhu	1	2
Bamboo	1	2
Banana Stem	1	2
Basil	1	2
Beta-Caryophyllene	1	2
Bifidobacterium Infantis	1	2
Bitter Orange	1	2
Black Pepper	1	2
Broccoli Sprouts	1	2
Cannabis	1	2
Chokeberry	1	2
Citrus naringin	1	2
Coconut Water	1	2
Combretum fragrans	1	2
Curry Leaves	1	2
D-Limonene	1	2
Dill	1	2
Ellagic Acid	1	2
Feijoa	1	2
Feverfew	1	2
Fisetin	1	2
Fucoidan	1	2
Gallic Acid	1	2
Garcinia Mangostana	1	2
Genistein	1	2
Geraniol	1	2
Ginseng	1	2
Ginseng (Korean)	1	2
Gotu Kola	1	2
Hawthorn	1	2
Hibiscus	1	2
Honokiol	1	2
Huperzine	1	2
Hydrogen Water	1	2
Kefir	1	2
Lactobacillus kefiranofaciens	1	2
Lactobacillus paracasei	1	2
Lactobacillus reuteri	1	2
Lettuce	1	2
Lithium	1	2
Lobelia	1	2
Lotus	1	2
Lutein	1	2
Magnolia	1	2
Maitake Mushroom	1	2
Mangiferin	1	2
Mango	1	2
Moringa oleifera	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Mulberry	1	2
Myricetin	1	2
Noni	1	2
Nutmeg	1	2
Onion	1	2
Orange	1	2
Orange: Mandarin	1	2
P-Coumaric Acid	1	2
Panax Ginseng	1	2
Propolis: Bee	1	2
Pterostilbene	1	2
Pycnogenol (Pine Bark)	1	2
Quercetin	1	2
Red Sage	1	2
Rutin	1	2
Safranal	1	2
Seaweed: Brown	1	2
Sesamol	1	2
Strawberry	1	2
Tarragon	1	2
Theaflavins	1	2
Thistle	1	2
Tualang Honey	1	2
Vitamin K2	1	2
Water: Deuterium Depleted	1	2
White Mulberry	1	2
ALA (Alpha-Linolenic Acid)	1	1
Anthocyanins	1	1
Catechin	1	1
Cocoa	1	1
Curcumin: Degradiation byproducts	1	1
Frankincense	1	1
Hyperforin	1	1
Mistletoe	1	1
Nigella sativa (aka Black Seed)	1	1
Peony	1	1
Rose: Essential Oil	1	1
Soursop	1	1
Syrian rue	1	1
Thymoquinone	1	1

Click here to read the entire abstract

Pubmed Data : Medicina (Kaunas). 2019 Sep 2 ;55(9). Epub 2019 Sep 2. PMID: 31480778

Article Published Date : Sep 01, 2019

Study Type : Meta Analysis, Review

Additional Links

Substances : 5-HTP (5-Hydroxytryptophan)

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

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Pubmed Data : J Clin Nurs. 2015 Aug 24. Epub 2015 Aug 24. PMID: 26299594

Article Published Date : Aug 23, 2015

Study Type : Meta Analysis

Additional Links

Diseases : Dementia

Therapeutic Actions : Music

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

Additional Keywords : Significant Treatment Outcome

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Omega-3 PUFA is effective in patients with diagnosis of major depressive disorder. Dec 31, 2013

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Pubmed Data : Neuropsychiatr Dis Treat. 2018 ;14:1297-1305. Epub 2018 May 21. PMID: 29849461

Article Published Date : Dec 31, 2017

Study Type : Meta Analysis

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

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St John's wort has comparable efficacy and safety when compared to SSRIs in patients with mild-to-moderate depression.Jan 02, 2017

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Pubmed Data : J Affect Disord. 2017 Jan 3 ;210:211-221. Epub 2017 Jan 3. PMID: 28064110

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Pubmed Data : Psychiatry Res. 2020 Jan 2 ;284:112749. Epub 2020 Jan 2. PMID: 31931272

Article Published Date : Jan 01, 2020

Study Type : Meta Analysis

Additional Links

Substances : Psilocybin

Diseases : Anxiety, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

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The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.Dec 31, 2018

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Pubmed Data : Psychol Res Behav Manag. 2019 ;12:297-305. Epub 2019 Apr 23. PMID: 31118846

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Pubmed Data : PLoS One. 2016 ;11(5):e0154195. Epub 2016 May 6. PMID: 27152523

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Pubmed Data : J Psychopharmacol. 2016 Dec ;30(12):1165-1180. PMID: 27909164

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Cancers: All, Depression

Pharmacological Actions : Antidepressive Agents

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Active commuting through natural environments is associated with better mental health.Jan 11, 2018

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Pubmed Data : Environ Int. 2018 12 ;121(Pt 1):721-727. Epub 2018 Oct 12. PMID: 30321847

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Pubmed Data : Arch Gen Psychiatry. 2006 Dec ;63(12):1358-67. PMID: 17146010

Article Published Date : Nov 30, 2006

Study Type : Human Study

Additional Links

Diseases : Suicidal Behavior, Suicidal Ideation

Pharmacological Actions : Antidepressive Agents

Problem Substances : Antidepressants

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An 8-week hatha yoga intervention resulted in statistically and clinically significant reductions in depression severity.Dec 31, 2016

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Pubmed Data : PLoS One. 2017 ;12(3):e0173869. Epub 2017 Mar 16. PMID: 28301561

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Baduanjin is an effective intervention for improving physical and psychological health outcomes among breast cancer survivors.Mar 31, 2019

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Pubmed Data : Eur J Oncol Nurs. 2019 Apr ;39:90-97. Epub 2019 Feb 2. PMID: 30850143

Article Published Date : Mar 31, 2019

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Depression

Therapeutic Actions : Qigong

Pharmacological Actions : Antidepressive Agents

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Behavioral activation in dietary change interventions can overcome the impact of depressive symptoms.Jun 19, 2015

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Pubmed Data : Ann Behav Med. 2015 Jun 20. Epub 2015 Jun 20. PMID: 26091977

Article Published Date : Jun 19, 2015

Study Type : Human Study

Additional Links

Substances : Fiber, Fruit: All, Vegetables: All

Diseases : Depression: Breast Cancer Related, Depressive Syndrome

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Dietary Modification, Significant Treatment Outcome

[+]

Beneficial effect of adjunct yoga therapy in depressive disorders.Oct 31, 2019

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Pubmed Data : J Altern Complement Med. 2015 Sep 18. Epub 2015 Sep 18. PMID: 26383034

Article Published Date : Sep 17, 2015

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Bright white light treatment for 5 weeks improved depression during pregnancy.Jun 30, 2011

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Pubmed Data : J Clin Psychiatry. 2011 Jul ;72(7):986-93. Epub 2011 Apr 5. PMID: 21535997

Article Published Date : Jun 30, 2011

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Light Therapy

Pharmacological Actions : Antidepressive Agents

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Chamomile may provide clinically meaningful antidepressant activity that occurs in addition to its previously observed anxiolytic activity.Aug 31, 2012

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Pubmed Data : Altern Ther Health Med. 2012 Sep-Oct;18(5):44-9. PMID: 22894890

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Pubmed Data : BMC Pregnancy Childbirth. 2016;16(1):239. Epub 2016 Aug 20. PMID: 27544544

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Consumption of dark chocolate may be associated with reduced odds of clinically relevant depressive symptoms.Jul 28, 2019

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Pubmed Data : Depress Anxiety. 2019 Jul 29. Epub 2019 Jul 29. PMID: 31356717

Article Published Date : Jul 28, 2019

Study Type : Human Study

Additional Links

Substances : Chocolate

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

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CoQ10 supplementation with 500 mg a day can improve fatigue and depression in patients with multiple sclerosis.Jan 19, 2015

Pubmed Data : Technol Health Care. 2014 ;22(3):453-8. PMID: 24704654

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Art Therapy, Music

Pharmacological Actions : Antidepressive Agents

[+]

Effects of ayahuasca on mental health and quality of life in naïve users.Mar 04, 2020

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Pubmed Data : Exp Neurol. 2019 Aug 22:113043. Epub 2019 Aug 22. PMID: 31446079

Article Published Date : Aug 21, 2019

Study Type : Human Study

Additional Links

Diseases : Post-Traumatic Stress Disorders (PTSD)

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents, Neuroprotective Agents

[+]

Exercise programs had positive effects in reducing the severity of depression in heart failure patients.Jul 31, 2019

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Pubmed Data : J Affect Disord. 2017 May 25 ;220:31-37. Epub 2017 May 25. PMID: 28577427

Article Published Date : May 24, 2017

Higher levels of medial prefrontal cortical glutamate were associated with negatively experienced ego dissolution.May 22, 2020

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Pubmed Data : Altern Ther Health Med. 2015 Jul-Aug;21(4):36-41. PMID: 26030115

Article Published Date : Jun 30, 2015

Study Type : Human Study

Additional Links

Diseases : Post-Traumatic Stress Disorders (PTSD)

Therapeutic Actions : Horticultural Therapy (Gardening)

Pharmacological Actions : Antidepressive Agents

[+]

Hypericum extract is superior to fluoxetine in treating depressed patients. May 31, 2005

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Pubmed Data : Int J Neuropsychopharmacol. 2005 Jun ;8(2):215-21. Epub 2004 Sep 30. PMID: 15458612

Article Published Date : May 31, 2005

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Pubmed Data : Front Psychol. 2018 ;9:487. Epub 2018 Apr 10. PMID: 29692750

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Fruit: All, Vegetables: All

Diseases : Anxiety, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Intense exercise increases circulating endocannabinoid and BDNF levels in humans-possible implications for reward and depression.May 31, 2012

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Pubmed Data : Psychoneuroendocrinology. 2012 Jun ;37(6):844-51. Epub 2011 Oct 24. PMID: 22029953

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Pubmed Data : Acta Neuropsychiatr. 2016 Jul 11:1-8. Epub 2016 Jul 11. PMID: 27396868

Article Published Date : Jul 10, 2016

Study Type : Human Study

Additional Links

Substances : Theanine

Diseases : Anxiety, Depressive Disorder

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

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Laughter yoga could be an effective intervention in reducing depression and anxiety among retired women.Jun 17, 2020

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Pubmed Data : J Women Aging. 2020 Jun 18:1-12. Epub 2020 Jun 18. PMID: 32552530

Article Published Date : Jun 17, 2020

Study Type : Human Study

Additional Links

Diseases : Anxiety, Depression

Therapeutic Actions : Laughter/Humor, Yoga

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

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Low serum 25(OH)D was associated with higher depressive symptom scores.Jul 03, 2015

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Substances : Probiotics

Diseases : Anxiety, Depression, Fibromyalgia

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Psilocybin modulated effective connectivity within the visual-limbic-prefrontal network during threat processing.Dec 31, 2015

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Pubmed Data : Neuroimage Clin. 2016 ;11:53-60. Epub 2015 Aug 22. PMID: 26909323

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Anxiety Disorders, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer.Nov 30, 2016

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Pubmed Data : J Psychopharmacol. 2016 Dec ;30(12):1181-1197. PMID: 27909165

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Pubmed Data : Cancer. 2013 May 1 ;119(9):1690-8. Epub 2013 Jan 25. PMID: 23355182

Article Published Date : Apr 30, 2013

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Depression, Fatigue: Cancer-Associated, Quality of Life: Poor

Therapeutic Actions : Qigong

Pharmacological Actions : Antidepressive Agents

[+]

R. damascena affected cognitive impairment of dementia patients and also had significant effects on improving depression and behavioural problems.Dec 31, 2017

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Saffron has beneficial effects on depression and homocysteine level in patients with major depression.Dec 31, 2017

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Pubmed Data : Avicenna J Phytomed. 2018 Jan-Feb;8(1):43-50. PMID: 29387573

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Saffron is a safe and effective treatment in improving hot flashes and depressive symptoms in post-menopausal healthy women.Dec 31, 2017

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Pubmed Data : Arch Gynecol Obstet. 2018 03 ;297(3):717-724. Epub 2018 Jan 13. PMID: 29332222

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Pubmed Data : Complement Ther Med. 2015 Aug ;23(4):598-602. Epub 2015 Jun 18. PMID: 26275653

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Pubmed Data : J Clin Psychiatry. 2017 May ;78(5):e522-e528. PMID: 28570792

Article Published Date : Apr 30, 2017

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Tai Chi

Pharmacological Actions : Antidepressive Agents

[+]

Targeting inflammation through diet in patients after spinal cord injury could help with depressive symptoms. Dec 31, 2014

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Pubmed Data : J Neuroinflammation. 2015 ;12(1):204. Epub 2015 Nov 6. PMID: 26545369

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Chlorella (Algae), Coenzyme Q10, Curcumin, DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid), Selenium, Vitamin E

Diseases : Depression, Spinal Cord Inflammation, Spinal Cord Injuries

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents

Additional Keywords : Dietary Modification, Diseases that are Linked, Supplementation

[+]

THC appears therapeutic for anorexia and disturbed behavior in patients with Alzheimer's disease.Aug 31, 1997

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Pubmed Data : Int J Geriatr Psychiatry. 1997 Sep ;12(9):913-9. PMID: 9309469

Article Published Date : Aug 31, 1997

Study Type : Human Study

Additional Links

Substances : Delta-tetrahydrocannabinol (THC)

Diseases : Anorexia: Dementia-Associated

Pharmacological Actions : Antidepressive Agents

[+]

The addition of bright light therapy might be effective in rapidly ameliorating depressive core symptoms of vulnerable difficult-to-treat depressed outpatients.Dec 31, 2014

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Pubmed Data : Neuropsychiatr Dis Treat. 2015 ;11:2331-8. Epub 2015 Sep 9. PMID: 26396517

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Diseases : Depression, Depression: Bipolar, Unipolar Depression

Therapeutic Actions : Integrative Medicine, Light Therapy

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Significant Treatment Outcome

Problem Substances : Antidepressants

[+]

The administration of a standardised saffron extract may improve anxiety and depressive symptoms.Dec 31, 2017

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Pubmed Data : Front Pharmacol. 2019 ;10:1325. Epub 2019 Nov 19. PMID: 31798447

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Substances : Ayahuasca

Diseases : Depression, Suicidal Behavior

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Pubmed Data : Rehabil Nurs. 2019 Sep/Oct;44(5):254-262. PMID: 31479435

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Diseases : Stroke: Ischemic

Therapeutic Actions : Exercise, Heat Therapy

Pharmacological Actions : Antidepressive Agents

[+]

These data highlight the therapeutic potential of ayahuasca in the treatment of mental health disorders, such as depression.Aug 12, 2018

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Pubmed Data : Intern Med. 2015 ;54(3):333-8. PMID: 25748743

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Diseases : Anxiety Disorders, Chronic Fatigue Syndrome, Depression

Therapeutic Actions : Sauna Therapy

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Significant Treatment Outcome

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This pilot study suggests that psilocybin with psychological support might produce lasting changes in attitudes and beliefs. Dec 31, 2017

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Pubmed Data : J Psychopharmacol. 2018 Jan 1:269881117748902. Epub 2018 Jan 1. PMID: 29338538

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Antidepressive Agents, depression, Psilocybin

[+]

This provides support for both the acceptability and the effectiveness of treatment by a homeopath for patients with self-reported depression.Jun 29, 2017

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Pubmed Data : Nutr J. 2019 Oct 7 ;18(1):58. Epub 2019 Oct 7. PMID: 31590668

Article Published Date : Oct 06, 2019

Study Type : Human Study

Additional Links

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

This study showed the effectiveness of anise in relieving the symptoms of postpartum depression.Dec 31, 2014

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Pubmed Data : Nutrition. 2018 Mar 21 ;54:48-53. Epub 2018 Mar 21. PMID: 29747090

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Pubmed Data : Biol Psychiatry. 2015 Oct 15 ;78(8):572-81. Epub 2014 Apr 26. PMID: 24882567

Article Published Date : Oct 14, 2015

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

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Pubmed Data : Psychiatr Pol. 2019 Oct 30 ;53(5):1053-1067. Epub 2019 Oct 30. PMID: 31955185

Article Published Date : Oct 29, 2019

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Cryotherapy

Pharmacological Actions : Antidepressive Agents

[+]

Whole-body cryotherapy with physical exercise training was an effective therapy for patients with multiple sclerosis.Oct 31, 2019

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Pubmed Data : Adv Clin Exp Med. 2019 Nov ;28(11):1477-1483. PMID: 30968613

Article Published Date : Oct 31, 2019

Study Type : Human Study

Additional Links

Diseases : Depression, Multiple Sclerosis

Therapeutic Actions : Cryotherapy, Exercise

Pharmacological Actions : Antidepressive Agents

[+]

Wild blueberry supplementation may be a potential prevention strategy for adolescent depression and may have benefits for public mental health.Mar 09, 2020

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Pubmed Data : Br J Nutr. 2020 Mar 10:1-22. Epub 2020 Mar 10. PMID: 32151287

Article Published Date : Mar 09, 2020

Study Type : Human Study

Additional Links

Substances : Blueberry

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

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A meta-analysis of exercise intervention for late-life depression.Jan 20, 2020

A meta-analysis of placebo-controlled trials of psychedelic-assisted therapy.Jun 11, 2020

A regular dose of gardening can improve public health.Feb 28, 2017

Acupuncture for perimenopausal depression is safe and effective. Dec 31, 2019

Altering the gut-brain axis with probiotics may be an approach to improve depression severity.Sep 16, 2019

Curcumin administration reduces depressive symptoms in patients with major depression.Nov 26, 2015

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.Dec 31, 2019

Curcumin for depression: a meta-analysis.Aug 18, 2019

Current evidence supports adjunctive use of SAMe, methylfolate, omega-3, and vitamin D with antidepressants to reduce depressive symptoms.Apr 25, 2016

Data from human trials provides evidence for the efficacy of use of bright light therapy when used as augmentation to standard antidepressants.Oct 19, 2016

DHEA may be one more effective alternative between the drugs used in the treatment of depression.Aug 16, 2018

Dietary interventions hold promise as a novel intervention for reducing symptoms of depression.Feb 04, 2019

Dietary magnesium intake was significantly associated with a reduced risk of depression.Feb 28, 2017

Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.Sep 01, 2019

Greater reductions in depressive symptoms were associated with higher frequency of yoga sessions per week.May 17, 2020

Hyperbaric oxygen therapy is effective and safe therapeutic approach for post-stroke depression.May 15, 2020

Impact of physical exercise on children with attention deficit hyperactivity disorders.Oct 31, 2019

Meditation appears to be effective for PTSD and depression symptoms.Aug 17, 2016

Meta-analysis: music listening is effective in reducing depressive symptoms in adults.Dec 01, 2011

Meta-analysis: Saffron (Crocus sativus L.) has value in treating major depressive disorder.Oct 31, 2013

Music therapy exerted a moderately large effect on disruptive behaviours of people with dementia, a moderate effect on anxiety levels and depressive moods.Aug 23, 2015

Omega-3 PUFA is effective in patients with diagnosis of major depressive disorder. Dec 31, 2013

Physical exercise is an effective intervention for depression. May 19, 2016

Pilates resulted in significant reductions in depressive and anxiety symptoms.Mar 31, 2018

Proprioceptive exercise may improve functional capacity, anxiety, and depression in diabetic neuropathy patients.Apr 15, 2020

Qigong appears to be beneficial for reducing depressive symptom severity.Jul 31, 2015

Qigong can improve the self-rating depression scale and self-rating anxiety scale scores of chronic obstructive pulmonary disease patients.Apr 30, 2019

Qigong exercise may be an option for older adults to improve physical ability, functional ability, balance and to lessen depression and anxiety.Dec 31, 2018

Qigong-based exercises may be effective for alleviating depression symptoms in individuals with major depressive disorder.Jan 06, 2019

Results suggest yoga may be beneficial as a component of treatment for both fatigue and depression in cancer survivors.Mar 31, 2020

Saffron could be an effective intervention for symptoms of depression and anxiety.May 27, 2019

Saffron could be considered as an alternative to synthetic antidepressants in the treatment of mild to moderate depression.Mar 31, 2020

Saffron could be considered as an alternative to synthetic antidepressants in the treatment of mild to moderate depression.Jan 06, 2020

Saffron has a significant effect on the severity of depression.Jul 22, 2018

Saffron was effective in the treatment of major depressive disorder and had comparable efficacy to synthetic antidepressants.Dec 31, 2017

St John's wort has comparable efficacy and safety when compared to SSRIs in patients with mild-to-moderate depression.Jan 02, 2017

Systematic review: psychedelics appear to be effective in significantly reducing symptoms of depression and anxiety and are well-tolerated.Jul 29, 2019

Tai Chi Chuan is a worthy complementary non-pharmacological resource towards depression and anxiety.Aug 20, 2019

The experimental effects of psilocybin on symptoms of anxiety and depression: A meta-analysis.Jan 01, 2020

The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.Dec 31, 2018

The findings suggest potentially beneficial effect of Qigong exercise on symptoms of anxiety among individuals with drug abuse.May 28, 2020

The results confirm the efficacy of the three herbal active substances in elderly patients with anxiety, depression, and dementia.Jun 19, 2015

There is general support for antidepressant and anxiolytic effects of probiotics.Apr 16, 2019

These results indicate a beneficial effect of the combination of EPA and DHA on depressed mood in women compared with placebo. Dec 31, 2014

These results provide additional support that exercise improves depressive symptoms in adults with arthritis and other rheumatic diseases.Apr 30, 2016

These results suggest that inositol may be beneficial for depressed patients.Dec 31, 2013

This meta-analysis shows that psychedelic treatments were safe and could contribute to a rapid improvement of depressive symptoms. May 24, 2020

This meta-analysis suggests that increasing 25(OH)D levels may be a useful approach to reduce the risk of depression in older adults.Jun 04, 2019

This systematic review provides support for the effectiveness of exercise in reducing postpartum depressive symptoms.Aug 29, 2017

Vitamin D supplementation can reduce negative emotions.May 03, 2020

Yoga interventions were effective in reducing depression.Dec 31, 2016

'Drug' effects and placebo effects are not necessarily additive, and mutually exclusive mechanisms may be operating in the two arms.Jan 01, 2009

A 12-week yoga program was effective in increasing parasympathetic tone and reducing depressive symptoms and perceived stress in women.Jan 03, 2017

A 4-week auricular acupressure plan led to improvement in sleep quality, anxiousness, and depressed mood in student nurses. Jan 31, 2018

A 4-week training of aerobic exercise significantly improves functional capacity in patients with major depressive disorder.Dec 31, 2015

A 5-week Seminar on the biopsychosocial-spiritual model of self-care improves anxiety, self-compassion, mindfulness, depression, and stress.May 29, 2019

A combination of probiotics and magnesium orotate attenuate depression.Mar 31, 2017

A recent trial spotlights bright light therapy and its utility beyond the winter months in treating major depressive disorder.Jun 30, 2016

A single dose psilocybin produced rapid and enduring anxiolytic and anti-depressant effects in patients with cancer-related psychological distress.Nov 30, 2016

Active commuting through natural environments is associated with better mental health.Jan 11, 2018

Acupuncture may achieve treatment effects by modulating the corticostriatal reward and motivation circuitry in MDD patients.Sep 15, 2016

Add-on treatment with curcumin has antidepressive effects in thai patients with major depression.Dec 31, 2017

Adherence to a healthy dietary pattern is associated with less severe depressive symptoms among adolescent girls.Dec 30, 2018

Adjuvant CoQ10 to a standard medication improved symptoms of depression after 8 weeks of treatment.Sep 30, 2018

Alterations in brain structure and amplitude of low-frequency after 8 weeks of mindfulness meditation training in meditation-naïve subjects.Jul 28, 2019

Among suicidal subjects who had ever used antidepressants, the current use of any antidepressant was associated with a markedly increased risk of attempted suicide and, at the same time, with a markedly decreased risk of completed suicide and death. Nov 30, 2006

An 8-week hatha yoga intervention resulted in statistically and clinically significant reductions in depression severity.Dec 31, 2016

An augmentation study of MSI-195 (S-adenosylmethionine) in major depressive disorder.Nov 30, 2018

An intervention of yoga plus coherent breathing led to a decrease in depressive symptoms in patients with major depressive disorder.Nov 30, 2017

Aromatherapy massage can be an effective and safe intervention to alleviate specific agitated behaviors and depressive mood in individuals with dementia.Aug 31, 2016

Aromatherapy massage can help in alleviating psychological and physiological responses among patients with acute coronary syndrome.Nov 30, 2017

Art therapy as an adjunctive treatment for major depressive disorder in the elderly can improve depressive and anxiety symptoms.Jun 30, 2018

Antidepressive Agents

View the Evidence:
771 Abstracts with Antidepressive Agents Research