Antidepressive Agents

Name	AC	CK
Saffron	29	313
Ayahuasca	27	203
Psilocybin	25	200
Vitamin D	21	196
Curcumin	29	180
Probiotics	29	155
Omega-3 Fatty Acids	12	96
Fruit: All	9	82
Vegetables: All	9	82
Psychedelics:All	13	65
Magnesium	7	55
DHA (Docosahexaenoic Acid)	4	50
EPA (Eicosapentaenoic Acid)	4	50
Lavender: Essential Oil	6	46
Melatonin	10	43
St. Johns Wort	5	42
St. John's Wort	3	40
Flavonoids	13	39
Ginsenosides	20	39
NAC (N-acetyl-L-cysteine)	6	36
Chamomile	6	35
Coenzyme Q10	5	34
Lemon Balm	5	34
Rhodiola (Tibetan Ginseng)	4	32
Cannabidiol	17	30
Fiber	3	30
Homeopathic Medicine: All	3	30
Crocin	7	29
Lysergic Acid Diethylamide (LSD)	9	29
Green Tea	6	26
Blueberry	4	24
Ginkgo biloba	3	24
Indian Mulberry	3	24
Delta-tetrahydrocannabinol (THC)	4	23
Paeoniflorin	12	23
Coffee	3	22
Oligosaccharides	2	22
Docosahexaenoic acid (DHA)	2	21
5-HTP (5-Hydroxytryptophan)	1	20
Carotenoids	2	20
Chlorella (Algae)	2	20
Dehydroepiandrosterone (DHEA)	1	20
Eicosapentaenoic acid (EPA)	1	20
Fish	2	20
Inositol	1	20
Lavender	2	20
Riboflavin (Vitamin B-2)	2	20
Rosemary	6	20
SAMe (S-adenosylmethionine)	1	20
Soy	2	20
Vitamin B-12	2	20
Vitamin B-6	2	20
Vitamin C	7	20
Anise	4	16
Lion's Mane (Hericium Erinaceus)	5	16
Fenugreek	4	15
Bifidobacterium Longum	3	14
Caffeine	3	14
Magnolia	3	14
Palmitoylethanolamide	4	14
Rose	4	14
Theanine	3	14
Ashwagandha	3	13
Bacopa	7	12
Cannabis	2	12
Dandelion	2	12
Fish Oil	2	12
Hesperidin	6	12
Lutein	2	12
Motherwort	2	12
Piperidines	2	12
Prebiotics	3	12
S-Adenosylmethionine (SAMe)	3	12
Black Tea	2	11
B-Carotene	1	10
Bifidobacterium Bifidum	1	10
Chocolate	1	10
Cysteine (see N-Acetylcysteine)	1	10
DHEA (Dehydroepiandrosterone)	1	10
Fennel	1	10
Ferulic acid	5	10
Green Leafy Vegetables	1	10
Hops	1	10
Kava Kava	1	10
Lactobacillus Acidophilus	1	10
Lactobacillus casei	1	10
Lactobacillus rhamnosus	1	10
Maca	1	10
Mushrooms: All	1	10
Nuts	1	10
Piperine	5	10
Potatoes	1	10
Quercetin	5	10
Seaweed	1	10
Selenium	1	10
Tryptophan	1	10
Vitamin B-3 (Niacin)	1	10
Vitamin B-5 (Pantothenic Acid)	1	10
Vitamin E	1	10
Walnut	1	10
White Tea	1	10
Resveratrol	5	9
Berberine	4	8
Perillaldehyde	4	8
Polyphenols	5	8
Arctigenin	3	6
Banana	3	6
Beta-Caryophyllene	3	6
Bifidobacterium	3	6
Chrysin	3	6
Flaxseed	3	6
Gastrodin	3	6
Ginseng	3	6
Honokiol	3	6
Magnolol	3	6
Mulberry	4	6
Naringenin	3	6
Passion Flower	4	6
Pomegranate	3	6
Silymarin	3	6
Cannabinoids	3	5
Hyperforin	3	5
Peony	3	5
Polyunsaturated Fatty Acids (PUFAs)	3	5
Thymoquinone	3	5
Ursolic Acid	3	5
Valerian	3	5
Allicin	2	4
Apigenin	2	4
Asparagus	2	4
Astaxanthin	2	4
Astragaloside	2	4
Bamboo	2	4
Chlorogenic Acid	2	4
Coconut Husk/Fiber	2	4
Fucoidan	2	4
Gardenia	2	4
Genipin	2	4
Ginseng (Korean)	2	4
Lactobacillus helveticus	2	4
Lactobacillus reuteri	2	4
Liquiritigenin	2	4
Lotus	2	4
Luteolin	2	4
Moringa oleifera	2	4
Musk (Animal)	2	4
Nettle	2	4
Paeonol	2	4
Royal Jelly	2	4
Safflower	2	4
Salvia divinorum	3	4
Sesamin	2	4
Silibinin	2	4
Sulforaphane	2	4
Tanshinone IIA	2	4
Anthocyanins	2	3
Bael	2	3
Catechin	2	3
Corn Silk	2	3
Kratom	3	3
Panax Notoginseng	2	3
Perilla	2	3
Poria cocos	2	3
Quince	2	3
Angelica	1	2
Arginine	1	2
Asiatic Acid	1	2
Astragalus	1	2
Bai Zhu	1	2
Banana Stem	1	2
Basil	1	2
Bifidobacterium Infantis	1	2
Bitter Orange	1	2
Black Pepper	1	2
Broccoli Sprouts	1	2
Burdock	1	2
Chia	1	2
Chokeberry	1	2
Chrysanthemum Morifolium	1	2
Citrus naringin	1	2
Coconut Water	1	2
Combretum fragrans	1	2
Crocetin	1	2
Curry Leaves	1	2
D-Limonene	1	2
Dill	1	2
Dogwood	1	2
Ellagic Acid	1	2
Eriodictyol	1	2
FOS (Fructooligosaccharides)	1	2
Feijoa	1	2
Feverfew	1	2
Fisetin	1	2
Folic Acid	1	2
Gallic Acid	1	2
Garcinia Mangostana	1	2
Garlic	1	2
Genistein	1	2
Geraniol	1	2
Geranium	1	2
Ginger	1	2
Goji	1	2
Gotu Kola	1	2
Grape Seed Extract	1	2
Gynostemma	1	2
Hawthorn	1	2
Hibiscus	1	2
Honeysuckle	1	2
Huperzine	1	2
Hydrogen Water	1	2
Isoquercitrin	1	2
Kefir	1	2
Kudzu	1	2
Lactobacillus kefiranofaciens	1	2
Lactobacillus paracasei	1	2
Lemon	1	2
Lemon Verbena	1	2
Lettuce	1	2
Ligustrazine	1	2
Lithium	1	2
Lobelia	1	2
Maitake Mushroom	1	2
Mangiferin	1	2
Mango	1	2
Medicinal Mushrooms	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Myricetin	1	2
Noni	1	2
Nutmeg	1	2
Okra	1	2
Oleuropein	1	2
Onion	1	2
Orange	1	2
Orange: Mandarin	1	2
P-Coumaric Acid	1	2
Panax Ginseng	1	2
Patchouli	1	2
Piperlongumine	1	2
Propolis: Bee	1	2
Pterostilbene	1	2
Pycnogenol (Pine Bark)	1	2
Radish	1	2
Red Sage	1	2
Rutin	1	2
Safranal	1	2
Sage	1	2
Schisandra	1	2
Seaweed: Brown	1	2
Sesamol	1	2
Spinach	1	2
Strawberry	1	2
Tarragon	1	2
Theaflavins	1	2
Thistle	1	2
Tualang Honey	1	2
Vitamin K2	1	2
Water: Deuterium Depleted	1	2
White Mulberry	1	2
Xanthohumol	1	2
Zataria multiflora	1	2
Zinc	1	2
ALA (Alpha-Linolenic Acid)	1	1
Babchi	1	1
Clove	1	1
Cocoa	1	1
Curcumin: Degradiation byproducts	1	1
EGCG (Epigallocatechin gallate)	1	1
Frankincense	1	1
Grape	1	1
Harmine	1	1
Mangosteen	1	1
Mistletoe	1	1
Nigella sativa (aka Black Seed)	1	1
Nobiletin	1	1
Oridonin	1	1
Reishi Mushroom	1	1
Rose: Essential Oil	1	1
Skullcap: Chinese	1	1
Soursop	1	1
Syrian rue	1	1
Xanthones	1	1
rhodiola	1	1

Click here to read the entire abstract

Pubmed Data : J Clin Nurs. 2015 Aug 24. Epub 2015 Aug 24. PMID: 26299594

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Pubmed Data : Complement Ther Med. 2015 Aug ;23(4):516-34. Epub 2015 May 27. PMID: 26275645

Article Published Date : Jul 31, 2015

Study Type : Meta Analysis, Review

Additional Links

Diseases : Depressive Syndrome

Therapeutic Actions : Qigong

Pharmacological Actions : Antidepressive Agents

[+]

Qigong can improve the self-rating depression scale and self-rating anxiety scale scores of chronic obstructive pulmonary disease patients.Apr 30, 2019

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Pubmed Data : JNCI Cancer Spectr. 2020 Apr ;4(2):pkz098. Epub 2019 Dec 17. PMID: 32368719

Article Published Date : Mar 31, 2020

Study Type : Meta Analysis

Additional Links

Diseases : Cancer: Fatigue

Therapeutic Actions : Yoga

Pharmacological Actions : Antidepressive Agents

[+]

Saffron could be an effective intervention for symptoms of depression and anxiety.May 27, 2019

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Pubmed Data : Neuropsychiatr Dis Treat. 2018 ;14:1297-1305. Epub 2018 May 21. PMID: 29849461

Article Published Date : Dec 31, 2017

Study Type : Meta Analysis

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

St John's wort has comparable efficacy and safety when compared to SSRIs in patients with mild-to-moderate depression.Jan 02, 2017

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Pubmed Data : J Affect Disord. 2017 Jan 3 ;210:211-221. Epub 2017 Jan 3. PMID: 28064110

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Pubmed Data : Phytomedicine. 2021 Aug 8 ;91:153699. Epub 2021 Aug 8. PMID: 34419735

Article Published Date : Aug 07, 2021

Study Type : Meta Analysis

Additional Links

Substances : Saffron

Diseases : Depression, Hypertension

Pharmacological Actions : Antidepressive Agents, Antihypertensive Agents, Hypoglycemic Agents

[+]

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Pubmed Data : J Psychopharmacol. 2020 May 25:269881120919957. Epub 2020 May 25. PMID: 32448048

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Pubmed Data : Br J Gen Pract. 2017 Aug 30. Epub 2017 Aug 30. PMID: 28855163

Article Published Date : Aug 29, 2017

Study Type : Meta Analysis, Review

Additional Links

Diseases : Depression: Postpartum

Therapeutic Actions : Exercise: Aerobic

Pharmacological Actions : Antidepressive Agents

[+]

This systematic review suggests that the efficacy of Morinda officinalis oligosaccharide capsules in the treatment of mild to moderate depression.Sep 27, 2020

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Pubmed Data : PLoS One. 2016 ;11(5):e0154195. Epub 2016 May 6. PMID: 27152523

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Pubmed Data : JMIR Ment Health. 2020 Nov 12 ;7(11):e17405. Epub 2020 Nov 12. PMID: 33180028

Article Published Date : Nov 11, 2020

Study Type : Human Study

Additional Links

Diseases : Depression: Postpartum

Therapeutic Actions : Meditation

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Significant Treatment Outcome

[+]

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Pubmed Data : PLoS One. 2017 ;12(3):e0173869. Epub 2017 Mar 16. PMID: 28301561

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Pubmed Data : J Gerontol Nurs. 2016 Sep 1 ;42(9):38-46. Epub 2016 Jun 20. PMID: 27319407

Article Published Date : Aug 31, 2016

Study Type : Human Study

Additional Links

Diseases : Dementia, Depression

Therapeutic Actions : Aromatherapy Massage

Pharmacological Actions : Antidepressive Agents

[+]

Aromatherapy massage can help in alleviating psychological and physiological responses among patients with acute coronary syndrome.Nov 30, 2017

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Pubmed Data : Int J Nurs Pract. 2017 Dec ;23(6). Epub 2017 Oct 25. PMID: 29071755

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Pubmed Data : Psychopharmacology (Berl). 2016 Mar ;233(5):823-9. Epub 2015 Nov 27. PMID: 26612618

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Pubmed Data : Eur J Oncol Nurs. 2019 Apr ;39:90-97. Epub 2019 Feb 2. PMID: 30850143

Article Published Date : Mar 31, 2019

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Depression

Therapeutic Actions : Qigong

Pharmacological Actions : Antidepressive Agents

[+]

Behavioral activation in dietary change interventions can overcome the impact of depressive symptoms.Jun 19, 2015

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Pubmed Data : Ann Behav Med. 2015 Jun 20. Epub 2015 Jun 20. PMID: 26091977

Article Published Date : Jun 19, 2015

Study Type : Human Study

Additional Links

Substances : Fiber, Fruit: All, Vegetables: All

Diseases : Depression: Breast Cancer Related, Depressive Syndrome

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Dietary Modification, Significant Treatment Outcome

[+]

Beneficial effect of adjunct yoga therapy in depressive disorders.Oct 31, 2019

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Pubmed Data : J Altern Complement Med. 2015 Sep 18. Epub 2015 Sep 18. PMID: 26383034

Article Published Date : Sep 17, 2015

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Pubmed Data : Arch Gen Psychiatry. 2011 Jan ;68(1):61-70. PMID: 21199966

Chronic depression treated successfully with novel taping therapy.Dec 31, 2015

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Pubmed Data : BMC Pregnancy Childbirth. 2016;16(1):239. Epub 2016 Aug 20. PMID: 27544544

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Consumption of dark chocolate may be associated with reduced odds of clinically relevant depressive symptoms.Jul 28, 2019

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Pubmed Data : Depress Anxiety. 2019 Jul 29. Epub 2019 Jul 29. PMID: 31356717

Article Published Date : Jul 28, 2019

Study Type : Human Study

Additional Links

Substances : Chocolate

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

CoQ10 supplementation with 500 mg a day can improve fatigue and depression in patients with multiple sclerosis.Jan 19, 2015

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Pubmed Data : J Tradit Complement Med. 2021 Jul ;11(4):375-380. Epub 2021 Jan 6. PMID: 34195032

Article Published Date : Jun 30, 2021

Study Type : Human Study

Additional Links

Diseases : Depression, Dyslipidemias, Hypothyroidism

Therapeutic Actions : Yoga

Pharmacological Actions : Antidepressive Agents, Hypolipidemic

[+]

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Pubmed Data : J Food Biochem. 2020 Oct 6:e13507. Epub 2020 Oct 6. PMID: 33025616

Article Published Date : Oct 05, 2020

Study Type : Human Study

Additional Links

Substances : Fenugreek

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

[+]

Electroacupuncture combined with probiotics brings good efficacy to patients with depression and chronic diarrhea.Oct 31, 2019

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Pubmed Data : Exp Ther Med. 2019 Nov ;18(5):3470-3474. Epub 2019 Sep 6. PMID: 31602222

[+]

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Pubmed Data : Am J Clin Nutr. 2016 09 ;104(3):704-14. Epub 2016 Jul 13. PMID: 27413131

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Flavonoids

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Higher levels of medial prefrontal cortical glutamate were associated with negatively experienced ego dissolution.May 22, 2020

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Pubmed Data : Altern Ther Health Med. 2015 Jul-Aug;21(4):36-41. PMID: 26030115

Article Published Date : Jun 30, 2015

Study Type : Human Study

Additional Links

Diseases : Post-Traumatic Stress Disorders (PTSD)

Therapeutic Actions : Horticultural Therapy (Gardening)

Pharmacological Actions : Antidepressive Agents

[+]

Hypericum extract is superior to fluoxetine in treating depressed patients. May 31, 2005

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Pubmed Data : Int J Neuropsychopharmacol. 2005 Jun ;8(2):215-21. Epub 2004 Sep 30. PMID: 15458612

Article Published Date : May 31, 2005

Study Type : Human Study

Additional Links

Substances : St. John's Wort

Diseases : Depression

Therapeutic Actions : Placebo Effect

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Phytotherapy, Plant Extracts, Superiority of Natural Substances versus Drugs

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Impact of saffron supplementation and resistance training on markers implicated in depression and happiness levels.Feb 05, 2021

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Pubmed Data : Physiol Behav. 2021 Feb 6 ;233:113352. Epub 2021 Feb 6. PMID: 33556410

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Pubmed Data : Front Psychol. 2018 ;9:487. Epub 2018 Apr 10. PMID: 29692750

Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Fruit: All, Vegetables: All

Diseases : Anxiety, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Intense exercise increases circulating endocannabinoid and BDNF levels in humans-possible implications for reward and depression.May 31, 2012

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Pubmed Data : Psychoneuroendocrinology. 2012 Jun ;37(6):844-51. Epub 2011 Oct 24. PMID: 22029953

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Pubmed Data : Med Sci Sports Exerc. 2021 Oct 1 ;53(10):2045-2053. PMID: 34519716

[+]

Low serum 25(OH)D levels and major depressive disorder diagnosis predicted an increased vulnerability to the stressful impact of the COVID-19 outbreak.Sep 13, 2020

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Pubmed Data : Psychoneuroendocrinology. 2020 Sep 14 ;122:104869. Epub 2020 Sep 14. PMID: 32956989

Article Published Date : Sep 13, 2020

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Coronavirus Infection, Depression, Vitamin D Deficiency

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

Low serum 25(OH)D was associated with higher depressive symptom scores.Jul 03, 2015

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Pubmed Data : Climacteric. 2015 Feb ;18(1):69-78. Epub 2014 Aug 7. PMID: 24931003

Article Published Date : Jan 31, 2015

Study Type : Human Study

Additional Links

Substances : Maca

Diseases : Depression, Hypertension

Pharmacological Actions : Antidepressive Agents, Antihypertensive Agents

Additional Keywords : Phytotherapy, Plant Extracts, Sex Hormone-Binding Globulin

[+]

Magnolia tea is recommended as a supplementary approach to ameliorate sleep quality of postpartum women, while alleviating their symptoms of depression.Feb 29, 2020

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Pubmed Data : Breast Cancer Res Treat. 2014 Jun ;145(3):683-95. Epub 2014 Apr 23. PMID: 24756186

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[+]

Participation in a yoga study decreases stress and depression scores for incarcerated women.Nov 30, 2020

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Pubmed Data : Int J Yoga Therap. 2020 Dec 1. Epub 2020 Dec 1. PMID: 33260196

Article Published Date : Nov 30, 2020

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Yoga

Pharmacological Actions : Antidepressive Agents

[+]

Physical activity and depression in older adults: the knowns and unknowns.Jan 17, 2021

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Pubmed Data : Psychiatry Res. 2021 Jan 18 ;297:113738. Epub 2021 Jan 18. PMID: 33515871

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Psilocybin modulated effective connectivity within the visual-limbic-prefrontal network during threat processing.Dec 31, 2015

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Pubmed Data : Neuroimage Clin. 2016 ;11:53-60. Epub 2015 Aug 22. PMID: 26909323

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Psilocybin

Diseases : Anxiety Disorders, Depression

Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents

[+]

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer.Nov 30, 2016

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Pubmed Data : J Psychopharmacol. 2016 Dec ;30(12):1181-1197. PMID: 27909165

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Pubmed Data : Int J Geriatr Psychiatry. 2020 Nov ;35(11):1393-1401. Epub 2020 Aug 6. PMID: 32662069

Article Published Date : Oct 31, 2020

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Qigong

Pharmacological Actions : Antidepressive Agents

[+]

Qigong may have therapeutic effects in the management of QOL among women who are receiving radiotherapy for breast cancer.Apr 30, 2013

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Pubmed Data : Cancer. 2013 May 1 ;119(9):1690-8. Epub 2013 Jan 25. PMID: 23355182

Article Published Date : Apr 30, 2013

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Depression, Fatigue: Cancer-Associated, Quality of Life: Poor

Therapeutic Actions : Qigong

Pharmacological Actions : Antidepressive Agents

[+]

R. damascena affected cognitive impairment of dementia patients and also had significant effects on improving depression and behavioural problems.Dec 31, 2017

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Article Published Date : Dec 31, 2017

Study Type : Human Study

Additional Links

Substances : Saffron

Diseases : Depression, Hot Flash

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Saffron was an efficacious herbal agent for the treatment of premenstrual dysphoric disorder with minimal adverse effects.Dec 31, 2019

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Pubmed Data : Complement Ther Med. 2015 Aug ;23(4):598-602. Epub 2015 Jun 18. PMID: 26275653

Pubmed Data : Med Sci Monit. 2019 Jan 13 ;25:389-394. Epub 2019 Jan 13. PMID: 30636257

Article Published Date : Jan 12, 2019

Study Type : Human Study

Additional Links

Substances : Dandelion

Diseases : Depression

Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator

[+]

Tai Chi as a mild to moderate mind-body exercise is suitable for older individuals who suffer from depression.Jan 06, 2018

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Pubmed Data : Neuropsychiatr Dis Treat. 2015 ;11:2331-8. Epub 2015 Sep 9. PMID: 26396517

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Diseases : Depression, Depression: Bipolar, Unipolar Depression

Therapeutic Actions : Integrative Medicine, Light Therapy

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Significant Treatment Outcome

Problem Substances : Antidepressants

[+]

The administration of a standardised saffron extract may improve anxiety and depressive symptoms.Dec 31, 2017

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Pubmed Data : Front Pharmacol. 2019 ;10:1325. Epub 2019 Nov 19. PMID: 31798447

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Substances : Ayahuasca

Diseases : Depression, Suicidal Behavior

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Risk Reduction

[+]

The genetic variation in APOE may influence the effect of exercise on depressive symptoms.Mar 02, 2017

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Pubmed Data : Qual Life Res. 2017 Mar 3. Epub 2017 Mar 3. PMID: 28255746

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Pubmed Data : J Psychiatr Pract. 2020 Nov ;26(6):444-460. PMID: 33275382

Article Published Date : Oct 31, 2020

Study Type : Human Study

Additional Links

Diseases : Depression

Therapeutic Actions : Exercise

Pharmacological Actions : Antidepressive Agents

[+]

The present investigation demonstrates that ayahuasca has significant and quite impressive acute antidepressive effects.Dec 31, 2014

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Pubmed Data : Rev Bras Psiquiatr. 2015 Jan-Mar;37(1):13-20. PMID: 25806551

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2018 Dec ;41:196-202. Epub 2018 Sep 26. PMID: 30477839

Article Published Date : Nov 30, 2018

Study Type : Human Study

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Substances : Saffron

Diseases : Depression, Diabetes Mellitus: Type 2

Pharmacological Actions : Antidepressive Agents

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View the Evidence: 939 Abstracts with Antidepressive Agents Research

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A meta-analysis of exercise intervention for late-life depression.Jan 20, 2020

A meta-analysis of placebo-controlled trials of psychedelic-assisted therapy.Jun 11, 2020

A regular dose of gardening can improve public health.Feb 28, 2017

Acupuncture for perimenopausal depression is safe and effective. Dec 31, 2019

Altering the gut-brain axis with probiotics may be an approach to improve depression severity.Sep 16, 2019

Curcumin administration reduces depressive symptoms in patients with major depression.Nov 26, 2015

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.Dec 31, 2019

Curcumin for depression: a meta-analysis.Aug 18, 2019

Current evidence supports adjunctive use of SAMe, methylfolate, omega-3, and vitamin D with antidepressants to reduce depressive symptoms.Apr 25, 2016

Data from human trials provides evidence for the efficacy of use of bright light therapy when used as augmentation to standard antidepressants.Oct 19, 2016

DHEA may be one more effective alternative between the drugs used in the treatment of depression.Aug 16, 2018

Dietary interventions hold promise as a novel intervention for reducing symptoms of depression.Feb 04, 2019

Dietary magnesium intake was significantly associated with a reduced risk of depression.Feb 28, 2017

Dose effect of psilocybin on primary and secondary depression.Sep 16, 2021

Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.Sep 01, 2019

Evidence suggests beneficial therapeutic effects of forest-based interventions on hypertension, stress, and mental-health disorders.Jan 10, 2021

Greater reductions in depressive symptoms were associated with higher frequency of yoga sessions per week.May 17, 2020

Hyperbaric oxygen therapy is effective and safe therapeutic approach for post-stroke depression.May 15, 2020

Impact of physical exercise on children with attention deficit hyperactivity disorders.Oct 31, 2019

Is electroacupuncture an effective and safe treatment for poststroke depression?Dec 31, 2020

Meditation appears to be effective for PTSD and depression symptoms.Aug 17, 2016

Meta-analysis: music listening is effective in reducing depressive symptoms in adults.Dec 01, 2011

Meta-analysis: Saffron (Crocus sativus L.) has value in treating major depressive disorder.Oct 31, 2013

Music therapy exerted a moderately large effect on disruptive behaviours of people with dementia, a moderate effect on anxiety levels and depressive moods.Aug 23, 2015

NAC provides certain noticeable benefits in attenuating substance craving and might help alleviate depressive symptoms and withdrawal syndrome.May 30, 2021

Omega-3 PUFA is effective in patients with diagnosis of major depressive disorder. Dec 31, 2013

Physical exercise is an effective intervention for depression. May 19, 2016

Pilates resulted in significant reductions in depressive and anxiety symptoms.Mar 31, 2018

Proprioceptive exercise may improve functional capacity, anxiety, and depression in diabetic neuropathy patients.Apr 15, 2020

Psilocybin as a new approach to treat depression and anxiety in the context of life-threatening diseases.Sep 04, 2020

Qigong appears to be beneficial for reducing depressive symptom severity.Jul 31, 2015

Qigong can improve the self-rating depression scale and self-rating anxiety scale scores of chronic obstructive pulmonary disease patients.Apr 30, 2019

Qigong exercise may be an option for older adults to improve physical ability, functional ability, balance and to lessen depression and anxiety.Dec 31, 2018

Qigong-based exercises may be effective for alleviating depression symptoms in individuals with major depressive disorder.Jan 06, 2019

Results suggest yoga may be beneficial as a component of treatment for both fatigue and depression in cancer survivors.Mar 31, 2020

Saffron could be an effective intervention for symptoms of depression and anxiety.May 27, 2019

Saffron could be considered as an alternative to synthetic antidepressants in the treatment of mild to moderate depression.Mar 31, 2020

Saffron could be considered as an alternative to synthetic antidepressants in the treatment of mild to moderate depression.Jan 06, 2020

Saffron has a significant effect on the severity of depression.Jul 22, 2018

Saffron was effective in the treatment of major depressive disorder and had comparable efficacy to synthetic antidepressants.Dec 31, 2017

St John's wort has comparable efficacy and safety when compared to SSRIs in patients with mild-to-moderate depression.Jan 02, 2017

Systematic review: psychedelics appear to be effective in significantly reducing symptoms of depression and anxiety and are well-tolerated.Jul 29, 2019

Tai Chi Chuan is a worthy complementary non-pharmacological resource towards depression and anxiety.Aug 20, 2019

The available evidence indicates that saffron is a safe plant for administration as a medicine and can improve diverse clinical outcomes.Aug 07, 2021

The effect of ginsenosides on depression in preclinical studies.Apr 30, 2021

The experimental effects of psilocybin on symptoms of anxiety and depression: A meta-analysis.Jan 01, 2020

The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.Dec 31, 2018

The findings suggest potentially beneficial effect of Qigong exercise on symptoms of anxiety among individuals with drug abuse.May 28, 2020

The results confirm the efficacy of the three herbal active substances in elderly patients with anxiety, depression, and dementia.Jun 19, 2015

There is general support for antidepressant and anxiolytic effects of probiotics.Apr 16, 2019

These results indicate a beneficial effect of the combination of EPA and DHA on depressed mood in women compared with placebo. Dec 31, 2014

These results provide additional support that exercise improves depressive symptoms in adults with arthritis and other rheumatic diseases.Apr 30, 2016

These results suggest that inositol may be beneficial for depressed patients.Dec 31, 2013

This meta-analysis of observational studies provides further evidence that fruit and vegetable intake was protectively associated with depression. Dec 31, 2017

This meta-analysis shows that psychedelic treatments were safe and could contribute to a rapid improvement of depressive symptoms. May 24, 2020

This meta-analysis suggests that increasing 25(OH)D levels may be a useful approach to reduce the risk of depression in older adults.Jun 04, 2019

This review shows that Qigong is beneficial for improving quality of life and relieving depression and anxiety.May 27, 2021

This systematic review provides support for the effectiveness of exercise in reducing postpartum depressive symptoms.Aug 29, 2017

This systematic review suggests that the efficacy of Morinda officinalis oligosaccharide capsules in the treatment of mild to moderate depression.Sep 27, 2020

Vitamin C may produce mood-elevating effects in patients with subclinical depression.Apr 22, 2021

Vitamin D supplementation can reduce negative emotions.May 03, 2020

Yoga for depression and anxiety symptoms in people with cancer.Mar 02, 2021

Yoga interventions were effective in reducing depression.Dec 31, 2016

'Drug' effects and placebo effects are not necessarily additive, and mutually exclusive mechanisms may be operating in the two arms.Jan 01, 2009

A 12-week yoga program was effective in increasing parasympathetic tone and reducing depressive symptoms and perceived stress in women.Jan 03, 2017

A 4-week auricular acupressure plan led to improvement in sleep quality, anxiousness, and depressed mood in student nurses. Jan 31, 2018

A 4-week training of aerobic exercise significantly improves functional capacity in patients with major depressive disorder.Dec 31, 2015

A 5-week Seminar on the biopsychosocial-spiritual model of self-care improves anxiety, self-compassion, mindfulness, depression, and stress.May 29, 2019

A combination of probiotics and magnesium orotate attenuate depression.Mar 31, 2017

A mobile health mindfulness intervention for women with moderate to moderately severe postpartum depressive symptoms.Nov 11, 2020

A recent trial spotlights bright light therapy and its utility beyond the winter months in treating major depressive disorder.Jun 30, 2016

A single dose psilocybin produced rapid and enduring anxiolytic and anti-depressant effects in patients with cancer-related psychological distress.Nov 30, 2016

Antidepressive Agents

View the Evidence:
939 Abstracts with Antidepressive Agents Research