Acetylcholinesterase Inhibitor

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21 Substances Researched for Acetylcholinesterase Inhibitor
NameACCKFocus
Sage110Locked
Black Pepper12Locked
Broccoli12Locked
Chokeberry12Locked
Curcumin12Locked
Evodia ruteacarpa12Locked
Ginkgo biloba12Locked
Kiwifruit12Locked
Licorice12Locked
Melatonin12Locked
Noni12Locked
Nutmeg12Locked
Vitamin C12Locked
Agrimony11Locked
Bacopa11Locked
Cannabis11Locked
Delta-tetrahydrocannabinol (THC)11Locked
Devils Claw11Locked
Green Tea11Locked
Muira Puama10Locked
Schisandra10Locked

View the Evidence:
92 Abstracts with Acetylcholinesterase Inhibitor Research

[+]

After supplementation of MetS patients with A. melanocarpa extract, a decrease in acetylcholinesterase activity and oxidative stress was noted.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:5670145. Epub 2018 Mar 26. PMID: 29780825
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Chokeberry
Diseases : Metabolic Syndrome X
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants
Additional Keywords : Plant Extracts
[+]

Sage has cholinesterase inhibiting properties which improve mood and cognitive performance.Apr 01, 2006

Pubmed Data : Neuropsychopharmacology. 2006 Apr;31(4):845-52. PMID: 16205785
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Cognitive Decline/Dysfunction, Mood Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Oligonol has strong preventative potential in diabetes mellitus and in Alzheimer's disease.Feb 29, 2016

Pubmed Data : Arch Pharm Res. 2016 Mar ;39(3):409-20. Epub 2016 Jan 2. PMID: 26724817
Article Published Date : Feb 29, 2016
Study Type : Human In Vitro
Additional Links
Substances : Lychee
Diseases : Alzheimer's Disease, Diabetes Mellitus: Type 2
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor
Additional Keywords : Dose Response, Proanthocyanidins
[+]

A combined plant extract WS-5 could be applied as a natural product therapy with a focus on neuroinflammation-related neurodegenerative disorders.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:5160293. Epub 2019 Apr 1. PMID: 31057649
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ginger, Turmeric
Diseases : Alzheimer's Disease, Neurodegenerative Diseases
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

A diet containing a mixture of P. montana and red ginseng extracts reversed learning and memory impairments.Jul 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Sci Biotechnol. 2018 Aug ;27(4):1193-1200. Epub 2018 Apr 4. PMID: 30263850
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean), Kudzu
Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

A. arguta might be considered possible substance to prevent neurodegeneration through AChE inhibition and strong antioxidant activity.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:876484. Epub 2015 Oct 21. PMID: 26576196
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Kiwifruit
Diseases : Amnesia: Drug-Induced, Brain: Oxidative Stress, Neurodegenerative Diseases
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

An extract of broccoli leaves could be used as a natural resource for ameliorating Aβ1-42-induced learning and memory impairment.May 03, 2016

Pubmed Data : J Agric Food Chem. 2016 May 4 ;64(17):3353-61. Epub 2016 Apr 22. PMID: 27079470
Article Published Date : May 03, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Broccoli
Diseases : Learning disorders, Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Ascorbic acid ameliorates behavioural deficits and neuropathological alterations in rat model of Alzheimer's disease.Feb 05, 2017

Pubmed Data : Environ Toxicol Pharmacol. 2017 Feb 6 ;50:200-211. Epub 2017 Feb 6. PMID: 28192749
Article Published Date : Feb 05, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
[+]

Beneficial effects of Urtica dioica on scopolamine-induced memory impairment.May 09, 2018

Pubmed Data : Drug Chem Toxicol. 2018 May 10:1-9. Epub 2018 May 10. PMID: 29745257
Article Published Date : May 09, 2018
Study Type : Animal Study
Additional Links
Substances : Nettle
Diseases : Brain: Oxidative Stress, Memory Disorders: Drug-Induced
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Centella asiatica attenuated the cognitive deficits in rats by restoring cholinergic function, attenuating oxidative stress.Mar 29, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxics. 2019 Mar 30 ;7(2). Epub 2019 Mar 30. PMID: 30935005
Article Published Date : Mar 29, 2019
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
Additional Keywords : Natural Substances Versus Drugs
[+]

Chokeberry extract has potential as a therapeutic agent for the prevention and treatment of neurodegenerative diseases.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:6145926. Epub 2016 Apr 30. PMID: 27239211
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Chokeberry
Diseases : Alzheimer's Disease, Memory Disorders: Drug-Induced, Neurodegenerative Diseases
Pharmacological Actions : Acetylcholinesterase Inhibitor
Additional Keywords : Plant Extracts
[+]

Co-administration of EGb 761 and donepezil exerted better anti-amnestic effect.Dec 24, 2020

Pubmed Data : J Ethnopharmacol. 2020 Dec 25 ;269:113711. Epub 2020 Dec 25. PMID: 33352242
Article Published Date : Dec 24, 2020
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Coconut leaf extract metabolites could decrease amyloid-β1-42 aggregation.Apr 20, 2017

Pubmed Data : Biomedicines. 2017 Apr 21 ;5(2). Epub 2017 Apr 21. PMID: 28536360
Article Published Date : Apr 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Coconut
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Cucurbita maxima seed oil may exert antiamnesic activity which may be attributed to the inhibition of AChE and inflammation.Aug 31, 2014

Pubmed Data : Z Naturforsch C. 2014 Sep-Oct;69(9-10):407-17. PMID: 25711042
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : Pumpkin Seeds
Diseases : Amnesia, Inflammation, Oxidative Stress
Pharmacological Actions : Acetylcholinesterase Inhibitor, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substances Versus Drugs, Plant Extracts
[+]

Curcumin administration suppress acetylcholinesterase gene expression in cadmium treated rats.May 16, 2017

Pubmed Data : Neurotoxicology. 2017 May 17. Epub 2017 May 17. PMID: 28527659
Article Published Date : May 16, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Alzheimer's Disease, Cadmium Poisoning
Pharmacological Actions : Acetylcholinesterase Inhibitor
Problem Substances : Cadmium
[+]

Curcumin improves episodic memory in cadmium induced memory impairment.Aug 04, 2016

Pubmed Data : Metab Brain Dis. 2016 Aug 5. Epub 2016 Aug 5. PMID: 27491636
Article Published Date : Aug 04, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cadmium Poisoning , Lipid Peroxidation, Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor, Adenosine deaminase inhibitor, Malondialdehyde Down-regulation
[+]

Curcumin lessens unpredictable chronic mild stress-induced depression and memory deficits by modulating oxidative stress and cholinergic activity.Jun 30, 2019

Pubmed Data : Pak J Pharm Sci. 2019 Jul ;32(4(Supplementary)):1893-1900. PMID: 31680089
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Anxiety, Depression
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
[+]

Curcuminoids (from Turmeric) enhance memory in mice through acetylcholinesterase inhibition. Feb 01, 2009

Pubmed Data : Pharmacol Biochem Behav. 2009 Feb;91(4):554-9. Epub 2008 Oct 1. PMID: 18930076
Article Published Date : Feb 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Memory Disorders, Memory Loss
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Dietary supplementation with walnut kernel or walnut septum extract can maintain the liver and brain health and reduce the risk of age-related diseases.May 13, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 May 14 ;9(5). Epub 2020 May 14. PMID: 32423149
Article Published Date : May 13, 2020
Study Type : Animal Study
Additional Links
Substances : Walnut
Diseases : Aging: Brain , Brain: Oxidative Stress
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Hypoglycemic Agents, Neuroprotective Agents
[+]

Effect of essential oils from ginger and turmeric rhizomes on some inflammatory biomarkers in cadmium induced neurotoxicity in rats.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2018 ;2018:4109491. Epub 2018 Oct 8. PMID: 30402094
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Ginger, Turmeric
Diseases : Cadmium Poisoning
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Essential Oils
Problem Substances : Cadmium
[+]

Evodia rutaecarpa has acetylcholinesterase inhibition and antiamnesic activities which may be useful in the treatment of AlzheimersJan 01, 2010

Pubmed Data : BMC Cancer. 2010;10:238. Epub 2010 May 26. PMID: 8923803
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Evodia ruteacarpa
Diseases : Alzheimer's Disease, Amnesia
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Extracts of A. princeps orientalis could be an effective treatment against cholinergic dysfunction.Dec 31, 2011

Pubmed Data : Am J Chin Med. 2012 ;40(5):993-1005. PMID: 22928830
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Japanese mugwort
Diseases : Dementia, Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Extracts of holy basil could become effective anti-amnesic treatments. Dec 03, 2016

Pubmed Data : J Ethnopharmacol. 2016 Dec 4 ;193:490-499. Epub 2016 Oct 8. PMID: 27725240
Article Published Date : Dec 03, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Holy Basil
Diseases : Amnesia, Amnesia: Drug-Induced
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Fucoxanthin might exhibit great therapeutic efficacy for the treatment of Alzheimer's disease.Mar 24, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2016 Mar 25 ;14(4). Epub 2016 Mar 25. PMID: 27023569
Article Published Date : Mar 24, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Ginkgo biloba ameloriates aluminum-induced learning and memory deficits in rats. Mar 01, 2006

Pubmed Data : Chin J Integr Med. 2006 Mar;12(1):37-41. PMID: 16571282
Article Published Date : Mar 01, 2006
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Aluminum Toxicity , Memory Disorders, Memory Loss
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Harmine alkaloids are potential agents to utilize in the management of neurodegenerative disorders.Nov 30, 2013

Pubmed Data : Pak J Biol Sci. 2013 Dec 1 ;16(23):1687-97. PMID: 24506035
Article Published Date : Nov 30, 2013
Study Type : Animal Study
Additional Links
Substances : Syrian rue
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Apoptotic, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Harmine could ameliorate impaired memory by enhancement of cholinergic neurotransmission.Dec 04, 2015

Pubmed Data : Eur J Pharmacol. 2015 Dec 5 ;768:96-107. Epub 2015 Oct 23. PMID: 26526348
Article Published Date : Dec 04, 2015
Study Type : Animal Study
Additional Links
Substances : Syrian rue
Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Acetylcholinesterase Inhibitor, Alzheimer's disease, Cognitive Decline/Dysfunction, Neuroprotective Agents, Syrian rue
[+]

Hibiscus represents a promising safe agent that can be repurposed for Alzheimer's disease.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2020 Aug ;128:110303. Epub 2020 May 29. PMID: 32480228
Article Published Date : Jul 31, 2020
Study Type : Animal Study
Additional Links
Substances : Hibiscus sabdariffa
Diseases : Alzheimer’s disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Huperzine-A contributed to the healing process in rats for damage occurring both in the brain and in the neuro-muscular system.Aug 31, 2017

Pubmed Data : Life Sci. 2017 Sep 1 ;184:47-57. Epub 2017 Jul 12. PMID: 28709849
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Huperzine
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
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Intranasal administration of nasal gel huperzine A may represent a safe and noninvasive therapeutic strategy for the treatment of Alzheimer's disease.Mar 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropsychopharmacology. 2011 Apr ;36(5):1073-89. Epub 2011 Feb 2. PMID: 21289607
Article Published Date : Mar 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Huperzine
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Wnt/β-catenin signaling pathway modulation
[+]

Lavandula stoechas is a very potent antioxidant and attenuates dementia.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1375. Epub 2018 Nov 23. PMID: 30532710
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Lavender
Diseases : Dementia
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Malondialdehyde Down-regulation
[+]

Lemon essential oil ameliorates age-associated cognitive dysfunction.May 10, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2020 May 11 ;12(9):8622-8639. Epub 2020 May 11. PMID: 32392535
Article Published Date : May 10, 2020
Study Type : Animal Study
Additional Links
Substances : Lemon
Diseases : Aging, Cognitive Decline/Dysfunction
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Essential Oils
[+]

Licorice (Glycyrrhiza glabra), Nutmega (Myristica fragrans), and vitamin C (ascorbic acid) have acetylcholinesterase-inhibiting associated with improved memory and learning. activity. Jun 01, 2006

Pubmed Data : J Med Food. 2006 Summer;9(2):281-3. PMID: 16822217
Article Published Date : Jun 01, 2006
Study Type : Animal Study
Additional Links
Substances : Licorice, Nutmeg, Vitamin C
Diseases : Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Myricetin is a potential multifunctional treatment for Alzheimer's disease.Jan 18, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 08 19 ;490(2):336-342. Epub 2017 Jun 12. PMID: 28619513
Article Published Date : Jan 18, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Myricetin
Diseases : Alzheimer's Disease, Brain: Oxidative Stress, Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Naringenin attenuates social defeat stress induced neurobehavioral deficits.Aug 31, 2018

Pubmed Data : Biomed Pharmacother. 2018 Sep ;105:714-723. Epub 2018 Jun 12. PMID: 29906750
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Social Behavior
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Naringenin may play a role in enhancing neuroprotective and cognition functions.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2020 ;15(1):e0227631. Epub 2020 Jan 16. PMID: 31945778
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
[+]

Naringin treatment may be useful to reduce wood smoke-induced oxidative stress and related ocular and pulmonary damage.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Ther Res Clin Exp. 2020 ;92:100586. Epub 2020 Apr 20. PMID: 32419878
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Air Pollution Linked Toxicity, Lung Injury: Smoke-Induced
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Antioxidants
[+]

Natural acetylcholinesterase Inhibitors could be useful in toxoplasma gondii induced memory impairment. Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Parasitol. 2016 Apr-Jun;11(2):177-185. PMID: 28096851
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Cognitive Decline/Dysfunction, Toxoplasma gondii Infection
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Neuroprotective and memory-enhancing effect of the combined extract of purple waxy corn cob and pandan in ovariectomized rats.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:5187102. Epub 2017 Jul 9. PMID: 28770022
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Corn: Purple
Diseases : Menopausal Syndrome
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Ovariectomy-Induced Changes
[+]

Neuroprotective mechanisms of selenium against arsenic-induced behavioral impairments in rats.Oct 30, 2019

Pubmed Data : Neurotoxicology. 2019 Oct 31 ;76:99-110. Epub 2019 Oct 31. PMID: 31678059
Article Published Date : Oct 30, 2019
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Arsenic Poisoning
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Problem Substances : Arsenic
[+]

Noni may have a protective effect against memory impairment. Nov 15, 2011

Pubmed Data : J Ethnopharmacol. 2011 Nov 15. Epub 2011 Nov 15. PMID: 22107832
Article Published Date : Nov 15, 2011
Study Type : Animal Study
Additional Links
Substances : Noni
Diseases : Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Opuntia ficus-indica might be promising candidate for treating Alzheimer disease.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2020 Oct ;27(10):2829-2838. Epub 2020 Jul 9. PMID: 32994743
Article Published Date : Sep 30, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aluminum Chloride
[+]

P. frutescens leaf exhibits excellent hypoglycemic activity in vitro and in vivo.Feb 02, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Foods. 2021 Feb 3 ;10(2). Epub 2021 Feb 3. PMID: 33546380
Article Published Date : Feb 02, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Perilla
Diseases : Breast Cancer, Cancers: All, Diabetes Mellitus: Type 2, Liver Cancer
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Antiproliferative , Tyrosinase inhibitors
[+]

Peganum harmala extracts exert beneficial effect on learning and memory processes in mice with scopolamine-induced memory impairment.May 22, 2017

Pubmed Data : J Ethnopharmacol. 2017 May 23 ;204:95-106. Epub 2017 Apr 23. PMID: 28442406
Article Published Date : May 22, 2017
Study Type : Animal Study
Additional Links
Substances : Syrian rue
Diseases : Alzheimer's Disease, Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Phloretin has nootropic, neuroprotective and neurotrophic activities in scopolamine induced memory impaired mice.Jul 31, 2015

Pubmed Data : Pharmacol Biochem Behav. 2015 Aug ;135:182-91. Epub 2015 Jun 10. PMID: 26071678
Article Published Date : Jul 31, 2015
Study Type : Animal Study
Additional Links
Substances : Phloretin
Diseases : Alzheimer's Disease, Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Brain-derived neurotrophic factor modulator, Catalase Up-Regulation, Neuroprotective Agents, Nootropic Agents, Superoxide Dismutase Up-regulation
[+]

Piper nigrum significantly improved learning and memory deficits associated with aluminium chloride and also showed the anticholinesterase activity with prevention of nerve degeneration.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Diagn Res. 2015 Apr ;9(4):FF01-4. Epub 2015 Apr 1. PMID: 26023568
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
Additional Keywords : Prevention
Problem Substances : Aluminum Chloride
[+]

Radish leaves may have preventive effects against memory deficits related to Alzheimer's disease.Jul 31, 2018

Pubmed Data : J Med Food. 2018 Aug ;21(8):769-776. PMID: 30110203
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Radish
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Repeated administration of Nigella sativa oil may exert memory enhancing effects against restrained stress.Aug 31, 2017

Pubmed Data : Pak J Pharm Sci. 2017 Sep ;30(5(Supplementary)):2039-2046. PMID: 29105641
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Memory Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
[+]

Schisandra chinensis extract may be a potential therapeutic candidate for Alzheimer's disease.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2020 ;2020:2804849. Epub 2020 Feb 20. PMID: 32148536
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Schisandra
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

Schisanhenol improves learning and memory in scopolamine-treated mice.Jan 31, 2019

Pubmed Data : Int J Neurosci. 2019 Feb ;129(2):110-118. Epub 2018 Oct 30. PMID: 30033800
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Schisandra
Diseases : Alzheimer's Disease, Brain: Oxidative Stress, Memory Disorders, Memory Disorders: Drug-Induced
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Sesquiterpenes and a monoterpenoid with acetylcholinesterase inhibitory activity from Valeriana officinalis.Mar 31, 2016

Pubmed Data : Fitoterapia. 2016 Apr ;110:142-9. Epub 2016 Mar 11. PMID: 26976216
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

The current study highlights P. vulgaris L. as an anti-dementia dietary supplement.Jan 17, 2017

Pubmed Data : J Agric Food Chem. 2017 Jan 18 ;65(2):291-300. Epub 2017 Jan 3. PMID: 28001065
Article Published Date : Jan 17, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prunella vulgaris
Diseases : Dementia
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

The study concludes that a macerated ethanolic extract of Indian propolis has anti-Alzheimer potential in rats.Jul 03, 2017

Pubmed Data : Biomed Pharmacother. 2017 Jul 4 ;93:543-553. Epub 2017 Jul 4. PMID: 28686968
Article Published Date : Jul 03, 2017
Study Type : Animal Study
Additional Links
Substances : Propolis: Bee
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Brain-derived neurotrophic factor modulator, Neuroprotective Agents
Additional Keywords : Acetylcholinesterase Inhibitor, Alzheimer's disease, Propolis: Bee
[+]

These findings may provide adequate evidence for the clinical and experimental benefits gained from huperzine A treatment.Jan 31, 2012

Pubmed Data : J Neurosci Res. 2012 Feb ;90(2):508-17. Epub 2011 Oct 17. PMID: 22002568
Article Published Date : Jan 31, 2012
Study Type : Transgenic Animal Study
Additional Links
Substances : Huperzine
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

This result indicated an important role for A. graveolens extract in preventing age-associated decline in cognitive function associated with depression.Jun 30, 2017

Pubmed Data : J Nat Med. 2017 Jul ;71(3):492-505. Epub 2017 Feb 15. PMID: 28205135
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Celery Oil
Diseases : Aging: Brain , Cognitive Decline/Dysfunction, Depression
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Zinc exhibits anti-amnesiac activity in mice. Jun 03, 2008

Pubmed Data : Behav Brain Res. 2008 Jun 3;189(2):381-6. Epub 2008 Feb 5. PMID: 18336929
Article Published Date : Jun 03, 2008
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Amnesia
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Antibacterial and in vitro antidementia effects of chokeberry leaf extracts.Aug 31, 2020

Pubmed Data : Food Sci Biotechnol. 2020 Sep ;29(9):1295-1300. Epub 2020 May 22. PMID: 32802569
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Chokeberry
Diseases : Dementia
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Bacterial Agents, Neuroprotective Agents
[+]

A review of the antitumour, antimicrobial, antioxidant and antiacetylcholinesterase effect of Ganoderma lucidum terpenoids and polysaccharides.Mar 12, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Mar 13 ;23(3). Epub 2018 Mar 13. PMID: 29534044
Article Published Date : Mar 12, 2018
Study Type : Review
Additional Links
Substances : Reishi Mushroom
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antimicrobial, Antioxidants, Antiproliferative
[+]

A. marmelos is a significant source of polyphenolic compounds with potential AChE inhibitory property and antioxidant activity.Feb 28, 2014

Pubmed Data : Psychogeriatrics. 2014 Mar ;14(1):1-10. PMID: 24646308
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Substances : Bael
Diseases : Alzheimer's Disease, Lipid Peroxidation
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

AChE inhibition by the methanolic extract of T. cordifolia was probably due to the synergism of the isoquinoline alkaloids.Nov 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Nov 18 ;24(22). Epub 2019 Nov 18. PMID: 31752124
Article Published Date : Nov 17, 2019
Study Type : In Vitro Study
Additional Links
Substances : Guduchi
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

Adjunctive treatment with huperzine A was associated with a faster resolution of the cognitive symptoms that frequently accompany major depressive disorder.Apr 24, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Shanghai Arch Psychiatry. 2016 Apr 25 ;28(2):64-71. PMID: 27605862
Article Published Date : Apr 24, 2016
Study Type : Review
Additional Links
Substances : Huperzine
Diseases : Depression, Depressive Disorder
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Agrimony has acetylcholinesterase inhibitory properties. Jan 01, 2007

Pubmed Data : Molecules. 2007;12(9):2130-9. Epub 2007 Sep 3. PMID: 17962731
Article Published Date : Jan 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Agrimony
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

An ethyl acetate soluble fraction of the roots of Harpagophytum procumbens was found to inhibit AChE activity.Dec 31, 2013

Pubmed Data : Arch Pharm Res. 2014 ;37(9):1124-9. Epub 2013 Dec 28. PMID: 24374905
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Devils Claw
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Cholinesterase Inhibitors
Additional Keywords : Plant Extracts
[+]

Annurca apple polyphenol extract affects acetyl-cholinesterase and mono-amine oxidase in vitro enzyme activity.Jan 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Jan 14 ;14(1). Epub 2021 Jan 14. PMID: 33466604
Article Published Date : Jan 13, 2021
Study Type : In Vitro Study
Additional Links
Substances : Apple Polyphenols
Diseases : Aging: Brain , Neurodegenerative Diseases
Pharmacological Actions : Acetylcholinesterase Inhibitor, Enzyme Inhibitors, Neuroprotective Agents
[+]

Antioxidant, cholinesterase inhibition activities and essential oil analysis of Nelumbo nucifera seeds.May 31, 2016

Pubmed Data : Nat Prod Res. 2016 Jun ;30(11):1335-8. Epub 2015 Jul 27. PMID: 26212099
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Lotus
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants
Additional Keywords : Essential Oils
[+]

Bacopa is an acetylcholinesterase inhibitor, neuroprotective, and has antioxidant effects. Aug 05, 2008

Pubmed Data : J Ethnopharmacol. 2008 Aug 5. [Epub ahead of print] PMID: 18755259
Article Published Date : Aug 05, 2008
Study Type : In Vitro Study
Additional Links
Substances : Bacopa
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
[+]

Carpolobia lutea possesses anti-AChE activity and beneficial antioxidant capacity indicative of its potential development as a treatment of Alzheimer's.Nov 30, 2017

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):1875-1883. PMID: 28629287
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carpolobia lutea
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants
Additional Keywords : Dose Response
[+]

Curcumin and piperine demonstrated promising neuroprotective effects.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Aging Neurosci. 2019 ;11:206. Epub 2019 Aug 27. PMID: 31507403
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Piperine
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
Additional Keywords : Natural Substance Synergy
[+]

Curcuminoids have anti-cholinesterase and anti-diabetic activities.Mar 12, 2017

Pubmed Data : Nat Prod Res. 2017 Mar 13:1-4. Epub 2017 Mar 13. PMID: 28287280
Article Published Date : Mar 12, 2017
Study Type : In Vitro Study
Additional Links
Substances : Bisdemethoxycurcumin, Curcuminoids, Demethoxycurcumin, Turmeric
Diseases : Alzheimer's Disease, Diabetes Mellitus: Type 2
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Antioxidants
[+]

Effect of Salvia miltiorrhiza on acetylcholinesterase: Enzyme kinetics and interaction mechanism merging with molecular docking analysis.May 21, 2019

Pubmed Data : Int J Biol Macromol. 2019 May 22 ;135:303-313. Epub 2019 May 22. PMID: 31128195
Article Published Date : May 21, 2019
Study Type : In Vitro Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Fruiting body extracts of T. pubescens demonstrated antioxidant related anti-diabetes, anti-dementia and anti-inflammatory activities.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2016 ;21(5). Epub 2016 May 16. PMID: 27196881
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Mushrooms: All
Diseases : Dementia, Diabetes Mellitus: Type 2, Inflammation
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Huperzine A is documented to be a promising agent for the treatment of Alzheimer's disease due to its potent acetylcholinesterase inhibitory activity.Dec 31, 2016

Pubmed Data : Pak J Pharm Sci. 2017 Jan ;30(1 Suppl):235-239. PMID: 28625948
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Huperzine
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor
Additional Keywords : Plant Extracts
[+]

Inhibitory effect of asiatic acid on acetylcholinesterase.Feb 14, 2012

Pubmed Data : Phytomedicine. 2012 Feb 15 ;19(3-4):311-6. Epub 2011 Nov 23. PMID: 22112723
Article Published Date : Feb 14, 2012
Study Type : In Vitro Study
Additional Links
Substances : Asiatic Acid
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Kinetics of acetylcholinesterase inhibition by hemp seed protein-derived peptides.Jun 30, 2019

Pubmed Data : J Food Biochem. 2019 Jul ;43(7):e12897. Epub 2019 May 15. PMID: 31353736
Article Published Date : Jun 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Hemp Seed
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Lichen depsides and depsidones showed neuroactive properties in vitro, suggesting their potential to treat CNS disorders.Nov 14, 2016

Pubmed Data : Phytomedicine. 2016 Nov 15 ;23(12):1527-1534. Epub 2016 Aug 31. PMID: 27765373
Article Published Date : Nov 14, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lichens
Diseases : Central Nervous System Diseases
Pharmacological Actions : Acetylcholinesterase Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

M. acuminata leaf is rich in bioactive flavonoids with relatively high antioxidative, antidiabetic, and anti-inflammatory activities.Jan 02, 2020

Pubmed Data : J Food Biochem. 2020 Jan 3:e13137. Epub 2020 Jan 3. PMID: 31899556
Article Published Date : Jan 02, 2020
Study Type : In Vitro Study
Additional Links
Substances : Banana, Kaempferol, Rutin
Diseases : Alzheimer's Disease, Diabetes Mellitus: Type 2, Inflammation
Pharmacological Actions : 15-Lipoxygenase (15-LOX) Inhibitor, Acetylcholinesterase Inhibitor, Alpha-amylase inhibitor, Alpha-glucosidase inhibitor , Anti-Inflammatory Agents, Enzyme Inhibitors
[+]

New cholinesterase inhibitory constituents from Lonicera quinquelocularis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(4):e94952. Epub 2014 Apr 14. PMID: 24733024
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Honeysuckle
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Cholinesterase Inhibitors
[+]

P. harmala had inhibitory activities on acetylcholinesterase and butyrylcholinesterase.Jun 19, 2015

Pubmed Data : J Ethnopharmacol. 2015 Jun 20 ;168:279-86. Epub 2015 Apr 8. PMID: 25862961
Article Published Date : Jun 19, 2015
Study Type : In Vitro Study
Additional Links
Substances : Syrian rue
Pharmacological Actions : Acetylcholinesterase Inhibitor
Additional Keywords : Acetylcholinesterase Inhibitor, Syrian rue
[+]

Petroselinum crispum L. seeds: chemical composition and biological activity.Aug 20, 2020

Pubmed Data : Nat Prod Res. 2020 Aug 21:1-6. Epub 2020 Aug 21. PMID: 32820642
Article Published Date : Aug 20, 2020
Study Type : In Vitro Study
Additional Links
Substances : Parsley
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Tyrosinase inhibitors
[+]

Piperlongumine B and analogs are promising and selective inhibitors for acetylcholinesterase.Aug 01, 2017

Pubmed Data : Eur J Med Chem. 2017 Aug 2 ;139:222-231. Epub 2017 Aug 2. PMID: 28802122
Article Published Date : Aug 01, 2017
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Possible role of common spices as a preventive and therapeutic agent for Alzheimer's disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Prev Med. 2017 ;8:5. Epub 2017 Feb 7. PMID: 28250905
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Cinnamon, Culinary Herbs and Spices, Ginger, Saffron, Turmeric
Diseases : Alzheimer's Disease, Dementia
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents
[+]

Potential application of Prunus armeniaca L. and P. domestica L. leaf essential oils as antioxidant and of cholinesterases inhibitors.Dec 20, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2018 Dec 21 ;8(1). Epub 2018 Dec 21. PMID: 30577585
Article Published Date : Dec 20, 2018
Study Type : In Vitro Study
Additional Links
Substances : Plum
Diseases : Alzheimer's Disease, Neurodegenerative Diseases
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants, Neuroprotective Agents
Additional Keywords : Essential Oils
[+]

Protective effect of fucoidan extract from Ecklonia cava on hydrogen peroxide-induced neurotoxicity.Nov 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microbiol Biotechnol. 2017 Nov 9. Epub 2017 Nov 9. PMID: 29121706
Article Published Date : Nov 08, 2017
Study Type : In Vitro Study
Additional Links
Substances : Fucoidan
Diseases : Hydrogen Peroxide Induced Toxicity
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

Tea polyphenols inhibit AChE as well as BChE and enhance the cholinergic neurotransmission by prolonging the time.Mar 20, 2016

Pubmed Data : CNS Neurol Disord Drug Targets. 2016 Mar 21. Epub 2016 Mar 21. PMID: 26996169
Article Published Date : Mar 20, 2016
Study Type : In Vitro Study
Additional Links
Substances : Green Tea
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Cholinesterase Inhibitors
[+]

THC appears to be superior as a Abeta aggregation to currently approved drugs prescribed for the treatment of Alzheimer's disease. Oct 31, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Pharm. 2006 Nov-Dec;3(6):773-7. PMID: 17140265
Article Published Date : Oct 31, 2006
Study Type : In Vitro Study
Additional Links
Substances : Cannabis, Delta-tetrahydrocannabinol (THC)
Pharmacological Actions : Acetylcholinesterase Inhibitor
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

The impact of some natural phenolic compounds on carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes.Nov 30, 2017

Pubmed Data : J Biochem Mol Toxicol. 2017 Dec ;31(12). Epub 2017 Sep 13. PMID: 28902458
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Chrysin, Citrus naringin, Ginger, Hesperidin, Polyphenols
Diseases : Hypoglycemia
Pharmacological Actions : Acetylcholinesterase Inhibitor, Alpha-glucosidase inhibitor , Hypoglycemic Agents
[+]

The root bark of M. alba and its active compounds might be promising candidates for preventive and therapeutic agents for Alzheimer's disease.Jan 15, 2017

Pubmed Data : Arch Pharm Res. 2017 Jan 16. Epub 2017 Jan 16. PMID: 28093699
Article Published Date : Jan 15, 2017
Study Type : In Vitro Study
Additional Links
Substances : White Mulberry
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Neuroprotective Agents
[+]

These findings may help to rationalize the wide use of Persian shallot for the treatment of inflammatory disorders.May 27, 2014

Pubmed Data : J Ethnopharmacol. 2014 May 28 ;154(1):176-82. Epub 2014 Apr 8. PMID: 24721027
Article Published Date : May 27, 2014
Study Type : In Vitro Study
Additional Links
Substances : Shallot
Diseases : Inflammation
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Cyclooxygenase 1 Inhibitor, Cyclooxygenase 2 Inhibitors
[+]

This research presents a systematic study on wolfberry polyphenols, including their bioactivities. Dec 31, 2016

Pubmed Data : Food Chem. 2017 Jan 1 ;214:644-54. Epub 2016 Jul 19. PMID: 27507521
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Goji, Polyphenols
Pharmacological Actions : Acetylcholinesterase Inhibitor, Antioxidants
[+]

This review examines the efficacy of curcumin to treat Alzheimer's disease.May 16, 2017

Pubmed Data : J Alzheimers Dis. 2017 May 17. Epub 2017 May 17. PMID: 28527218
Article Published Date : May 16, 2017
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anticholesteremic Agents, Neuroprotective Agents
[+]

Muira Puama's anticholinesterase activity may be responsible for its traditional therapeutic role associated with cognition.Jun 01, 2003

Pubmed Data : Pharmacol Biochem Behav. 2003 Jun;75(3):645-50. PMID: 12895682
Article Published Date : Jun 01, 2003
Additional Links
Substances : Muira Puama
Diseases : Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Schisandra inhibits the acetylcholinesterase enzyme, which may explain its positive effect on memory. Jun 01, 2007

Pubmed Data : Arch Pharm Res. 2007 Jun;30(6):685-90. PMID: 17679544
Article Published Date : Jun 01, 2007
Additional Links
Substances : Schisandra
Pharmacological Actions : Acetylcholinesterase Inhibitor

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