Sleep Disorders

Name	AC	CK
Melatonin	4	52
Vitamin D	3	40
Homeopathic Medicine: All	2	20
Cannabis	3	14
Crocetin	2	12
Passion Flower	2	12
Cannabinoids	2	11
Chamomile	1	10
Delta-tetrahydrocannabinol (THC)	1	10
Kiwifruit	1	10
Lactobacillus casei	1	10
Lavender: Essential Oil	1	10
Melissa (Lemonbalm)	1	10
Palmitoylethanolamide	1	10
Probiotics	1	10
Sesame Seed Oil	1	10
Tart Cherry	1	10
Valerian	1	10
Cannabidiol	3	6
Ginsenosides	2	4
Aloe Vera	1	2
Ashwagandha	1	2
Carotenoids	1	2
Crocin	1	2
Ginseng (Siberian)	1	2
Gotu Kola	1	2
Guduchi	1	2
Lactobacillus plantarum	1	2
Lettuce	1	2
Lotus	1	2
Pine Needle	1	2
Quercetin	1	2
Red Cabbage	1	2
Rose	1	2
Saffron	1	2
Skullcap: Chinese	1	2

Name	AC	CK
Energy Drinks	2	20
Lovastatin	2	13
Metoprolol	2	13
Aromatic hydrocarbons	1	10
Arsenic	1	10
Bisphenol A	1	10
Cell Phone Exposure	1	10
Heavy Metals	1	10
Morphine	1	10
Pesticides	1	10
Phthalates	1	10
Statin Drugs	1	10
Simvastatin	1	3
Barbiturates	1	2

Name	AC	CK
Acupressure	5	41
Aromatherapy	2	30
Cognitive Behavioural Approaches	2	20
Yoga	2	20
Tai Chi	2	12
Acupressure: Auricular	1	10
Amber Lenses	1	10
Ayurvedic Medicine	1	10
Blue Light Blocking	1	10
Exercise	1	10
Exercise: Aerobic	1	10
Floatation Tank Immersion	1	10
Hyperbaric Treatment	1	10
Light Therapy	1	10
Meditation	1	10
Pilates	1	10
Qigong	1	10
Relaxation Therapy	1	10
Therapeutic Breathing	1	10
Reiki Therapy	1	3

Name	AC	CK
Blue Light (400−495 nm)	4	40
Electromagnetic Fields	1	10
Mobile Phone Radiation	1	10
Vaccination: All	1	10
Western Diet	1	10
Shift Work	1	1

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Pubmed Data : Holist Nurs Pract. 2017 Mar/Apr;31(2):102-109. PMID: 28181975

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Sleep Disorders

Therapeutic Actions : Acupressure: Auricular

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Delta-9-tetrahydrocannabinol appears to be therapeutic for nighttime agitation in severe dementia.Apr 30, 2006

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Pubmed Data : Psychopharmacology (Berl). 2006 May ;185(4):524-8. Epub 2006 Mar 7. PMID: 16521031

Article Published Date : Apr 30, 2006

Study Type : Human Study

Additional Links

Substances : Delta-tetrahydrocannabinol (THC)

Diseases : Dementia, Sleep Disorders

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Electromagnetic field emissions may downregulate the synthesis of beta trace protein, the key enzyme in the synthesis of prostaglandin D2 an endogenous sleep-promoting neurohormone in the brain.Aug 01, 2010

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Pubmed Data : Int J Mol Med. 2010 Aug ;26(2):301-6. PMID: 20596612

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Indian J Occup Environ Med. 2010 Sep ;14(3):66-70. PMID: 21461157

Article Published Date : Sep 01, 2010

Study Type : Human Study

Additional Links

Diseases : Lipid Peroxidation, Oxidative Stress, Sleep Disorders

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation

Adverse Pharmacological Actions : Malondialdehyde (MDA) Up-Regulation, Melatonin Interference, Oxidant

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Energy drink intake had detrimental effects related to stress, sleep dissatisfaction, mood, and suicidality in combination with junk food consumption.Oct 12, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutr J. 2016 Oct 13 ;15(1):87. Epub 2016 Oct 13. PMID: 27737671

Article Published Date : Oct 12, 2016

Study Type : Human Study

Additional Links

Diseases : Sleep Disorders, Stress, Suicidal Behavior

Additional Keywords : Risk Factors

Anti Therapeutic Actions : Western Diet

Problem Substances : Energy Drinks

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Exposure to mobile phone radiation in talk mode markedly and significantly delays sleep latency in humans.Jun 21, 2007

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Pubmed Data : Neurosci Lett. 2007 Jun 21 ;421(1):82-6. Epub 2007 May 24. PMID: 17548154

Article Published Date : Jun 21, 2007

Study Type : Human Study

Additional Links

Diseases : Sleep Disorders

Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Mobile Phone Radiation

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Flotation therapy helped relieve participants stress, anxiety, depression and relief from long lasting pain, while increasing sleep quality and optimism levels. Dec 31, 2013

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Pubmed Data : BMC Complement Altern Med. 2014 ;14:417. Epub 2014 Oct 25. PMID: 25344737

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Homeopathic Passiflora Compose could be an alternative to the use of psychotropic drugs for first intention treatment of anxiety and sleep disorders.Jan 31, 2016

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Pubmed Data : Homeopathy. 2016 Feb ;105(1):84-91. Epub 2015 Aug 29. PMID: 26828002

Article Published Date : Jan 31, 2016

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Pubmed Data : Pathol Biol (Paris). 2002 Jul ;50(6):369-73. PMID: 12168254

Article Published Date : Jun 30, 2002

Study Type : Human Study

Additional Links

Diseases : Depression, Fatigue, Headache, Sleep Disorders

Anti Therapeutic Actions : Mobile Phone Radiation

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Kiwifruit consumption before sleep improved sleep onset, duration, and efficiency in adult patients.Dec 31, 2010

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asia Pac J Clin Nutr. 2011 ;20(2):169-74. PMID: 21669584

Article Published Date : Dec 31, 2010

Study Type : Human Study

Additional Links

Substances : Kiwifruit

Diseases : Sleep Disorders

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Lavender essential oil increased quality of sleep and reduced level of anxiety in patients with coronary artery disease.Jul 26, 2015

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Pubmed Data : Nurs Crit Care. 2015 Jul 27. Epub 2015 Jul 27. PMID: 26211735

Article Published Date : Jul 26, 2015

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Mobile phone exposure interferes with sleep patterns in subjects with mobile phone-related symptoms.Sep 20, 2010

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Pubmed Data : Bioelectromagnetics. 2010 Sep 20. Epub 2010 Sep 20. PMID: 20857453

Article Published Date : Sep 20, 2010

Study Type : Human Study

Additional Links

Diseases : Insomnia, Mobile Phone-Induced Oxidative Stress, Sleep Disorders

Problem Substances : Cell Phone Exposure

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Mobile phone exposure may affect melatonin onset time.Feb 01, 2006

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Pubmed Data : Int J Radiat Biol. 2006 Feb ;82(2):69-76. PMID: 16546905

Article Published Date : Feb 01, 2006

Study Type : Human Study

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Pubmed Data : Front Hum Neurosci. 2019 ;13:425. Epub 2019 Dec 2. PMID: 31849629

Article Published Date : Dec 31, 2018

Study Type : Human Study

Additional Links

Diseases : Insomnia, Sleep Disorders

Therapeutic Actions : Music

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2019 Aug 26 ;9(1):12339. Epub 2019 Aug 26. PMID: 31451704

Article Published Date : Aug 25, 2019

Study Type : Human Study

Additional Links

Substances : Rice Bran

Diseases : Sleep Disorders

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Sesame oil Shirodhara may be a safe potential treatment to improve sleep quality and QOL in persons with sleep problems.Dec 31, 2015

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Pubmed Data : J Altern Complement Med. 2016 Jan ;22(1):52-8. Epub 2015 Dec 15. PMID: 26669255

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Sesame Seed Oil

Diseases : Sleep Disorders

Therapeutic Actions : Ayurvedic Medicine

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Short-term sleep deprivation leads to decreased systemic redox metabolites and altered epigenetic status.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Diabetes Metab Disord. 2015 ;14:62. Epub 2015 Jul 22. PMID: 26203431

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Vitamin D

Diseases : Anxiety, Depression, Sleep Disorders, Vitamin D Deficiency

Additional Keywords : Risk Factors

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Statin drugs are associated with adverse mental effects.Sep 20, 1997

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Pubmed Data : Tidsskr Nor Laegeforen. 1997 Sep 20 ;117(22):3210-3. PMID: 9411859

Article Published Date : Sep 20, 1997

Study Type : Human Study

Additional Links

Diseases : Aggression, Anxiety Disorders, Depression, Impotence, Sleep Disorders, Statin-Induced Pathologies

Pharmacological Actions : Anticholesteremic Agents

Problem Substances : Statin Drugs

Adverse Pharmacological Actions : Neurotoxic

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Subjective sleepiness was significantly lower after relaxation above a struck singing bowl.Dec 31, 2019

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Pubmed Data : J Psychiatr Res. 2017 04 ;87:61-70. Epub 2016 Dec 12. PMID: 28017916

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Diseases : Sleep Disorders

Anti Therapeutic Actions : Blue Light (400−495 nm)

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There was an association between C-reactive protein and the symptoms of fatigue, restless sleep, low energy and feeling depressed.Aug 21, 2016

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Pubmed Data : Brain Behav Immun. 2016 Aug 22. Epub 2016 Aug 22. PMID: 27562420

Article Published Date : Aug 21, 2016

Study Type : Human Study

Additional Links

Diseases : C-Reactive Protein, Depression, Fatigue, Inflammation, Sleep Disorders

Additional Keywords : Diseases that are Linked, Increased Risk

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This retrospective observational study suggests that treatment of anxiety and sleep disorders with Datif-PC can produce notable improvements.Sep 30, 2013

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Pubmed Data : Homeopathy. 2013 Oct ;102(4):254-61. PMID: 24050771

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Pubmed Data : Complement Ther Clin Pract. 2013 Nov ;19(4):193-6. Epub 2013 Sep 10. PMID: 24199972

Article Published Date : Oct 31, 2013

Study Type : Human Study

Additional Links

Substances : Melissa (Lemonbalm), Valerian

Diseases : Postmenopausal Disorders: Insomnia, Sleep Disorders

Additional Keywords : Phytotherapy, Plant Extracts

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Wearing blue light-blocking glasses in the evening advances circadian rhythms in the patients with delayed sleep phase disorder.Dec 31, 2015

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Pubmed Data : Chronobiol Int. 2016 ;33(8):1037-44. Epub 2016 Jun 20. PMID: 27322730

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Pubmed Data : Ann Pharmacother. 2001 Oct ;35(10):1292. PMID: 11675864

Article Published Date : Oct 01, 2001

Study Type : Human: Case Report

Additional Links

Diseases : Nightmare, Sleep Disorders

Pharmacological Actions : Antihypertensive Agents

Problem Substances : Metoprolol, Simvastatin

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Additional Keywords : Plant Extracts

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Aloe vera extract has sedative-hypnotic effects in animals. Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Pharm Res. 2016 ;15(1):293-300. PMID: 27610170

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Aloe Vera

Diseases : Insomnia, Sleep Disorders

Pharmacological Actions : Hypnotics and Sedatives

Additional Keywords : Plant Extracts

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Ashwagandha may serve as an effective dietary supplement for management of sleep deprivation induced stress and associated functional impairments.Dec 20, 2016

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Pubmed Data : Mol Cell Biochem. 2016 Dec 21. Epub 2016 Dec 21. PMID: 28004351

GABA and l-theanine mixture decreases sleep latency and improves NREM sleep.Nov 30, 2019

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Pubmed Data : Nat Med. 2017 May 8. Epub 2017 May 8. PMID: 28481358

Article Published Date : May 07, 2017

Study Type : Animal Study

Additional Links

Diseases : Chronic Pain, Insomnia, Sleep Disorders

Additional Keywords : Increased Risk

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Lactobacillus plantarum MTCC 9510 supplementation protects from chronic unpredictable and sleep deprivation induced behaviour.Mar 24, 2018

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Pubmed Data : J Appl Microbiol. 2018 Mar 25. Epub 2018 Mar 25. PMID: 29575441

Article Published Date : Mar 24, 2018

Study Type : Animal Study

Additional Links

Substances : Lactobacillus plantarum

Diseases : Sleep Disorders

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

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Low intensity extremely high frequency electromagnetic radiation (37 GHz) can induce electrosleep in rats.May 01, 2004

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Pubmed Data : Growth Factors. 2017 Feb ;35(1):12-18. Epub 2017 Apr 17. PMID: 28415893

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Diseases : Sleep Disorders

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Sleep promoting effect of luteolin in mice via adenosine A1 and A2A receptors.Oct 31, 2019

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Pubmed Data : Avicenna J Phytomed. 2020 Jan-Feb;10(1):70-77. PMID: 31921609

Article Published Date : Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Curr Psychiatry Rep. 2017 Apr ;19(4):23. PMID: 28349316

Article Published Date : Mar 31, 2017

Study Type : Review

Additional Links

Substances : Cannabidiol, Cannabinoids

Diseases : Sleep Disorders

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Humulone modulation of GABA A receptors and its role in hops sleep-promoting activity.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Neurosci. 2020 ;14:594708. Epub 2020 Oct 14. PMID: 33177986

Article Published Date : Dec 31, 2019

Study Type : In Vitro Study

Additional Links

Substances : Hops

Diseases : Sleep Disorders

Pharmacological Actions : GABA Modulators

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Mental and physical health in older people are negatively affected during the social distancing for COVID-19.Dec 31, 2019

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View the Evidence: 157 Abstracts with Sleep Disorders Research

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Melatonin is effective in advancing sleep-wake rhythm and endogenous melatonin rhythm in delayed sleep phase disorder.Dec 01, 2010

Pineal calcification may contribute to melatonin deficiency and circadian timing irregularities.Dec 01, 1999

Readily available aromatherapy treatments appear to be effective and promote sleep. Jan 31, 2015

The effect of yoga on sleep quality and insomnia in women with sleep problems.Apr 30, 2020

This meta-analysis clearly supports the use of melatonin as a management for patients with secondary sleep disorders.Jun 13, 2018

This meta-analysis showed a significant improvement in sleep quality and generalized anxiety disorder.Jun 01, 2019

This meta-analysis suggest that vitamin D deficiency is associated with a higher risk of sleep disorders.Sep 30, 2018

16 weeks of mat-based Pilates training significantly improves the perceived health status and some sleep quality indices among elderly women.Dec 31, 2017

A 4-week auricular acupressure plan led to improvement in sleep quality, anxiousness, and depressed mood in student nurses. Jan 31, 2018

A single session of cognitive behavioral therapy for insomnia was found to be sufficiently efficacious for a significant proportion of those with acute insomnia. Dec 31, 2014

Acupressure improves the quality of sleep in Iranian elderly nursing home residents.May 01, 2010

Acupressure is a promising intervention that may improve well-being for nursing home residents with sleep disturbances.Feb 01, 2017

Acute exposure to evening blue‐enriched light impacts on human sleep.Sep 30, 2013

An independent association between sleep duration and the prevalence of periodontitis was found in this study. Feb 16, 2017

Aromatherapy can improve the sleep quality of cancer patients.Jan 01, 2020

Aromatherapy involving lavender steam inhalation increased sleep quality and quality of life in women with sleep deprivation problems during menopause.Jun 08, 2020

Association between long-term exposure to ambient air pollutants and excessive daytime sleepiness.Feb 02, 2020

Auricular acupressure had beneficial effects on reducing sleep disturbance, and improving students' anxiety, and depressed moods.Jun 05, 2017

Auricular acupressure therapy had beneficial effects on the stress and sleep status of middle-aged women in South Korea.Dec 31, 2016

Beneficial effects of Lactobacillus casei strain Shirota on academic stress-induced sleep disturbance in healthy adults.Apr 25, 2017

Benefits of a home treatment program using guided imagery relaxation based on audio recordings for people with fibromyalgia.Dec 31, 2018

Both melatonin and light treatment have positive effects on various sleep outcomes.Oct 09, 2016

Cannabis-based medicine is effective in reducing pain and sleep disturbance in patients with multiple sclerosis related central neuropathic pain and is mostly well tolerated.Sep 27, 2005

Chamomile tea may be recommended to postpartum women as a supplementary approach to alleviating depression and sleep quality problems.Jan 31, 2016

Chronic alteration of circadian rhythm is related to impaired lung function and immune response. Jun 18, 2020

Circadian phase, dynamics of subjective sleepiness and sensitivity to blue light in young adults complaining of a delayed sleep schedule.May 31, 2017

Cognitive behavioural intervention combined with a breathing exercise could improve sleep quality in patients with major depression.Oct 31, 2015

Consumption of energy drinks was significantly associated with changes in sleep quality and patterns of students.Jun 30, 2017

COVID-19: Preliminary data on the impact of social distancing on loneliness and mental health.Dec 31, 2019

Cyclic meditation (CM) which combines yoga postures interspersed with supine rest improves the objective and subjective quality of sleep. Jul 01, 2009

Daily occupational EMF exposure was positively associated with poor sleep quality.Jan 01, 2014

Delta-9-tetrahydrocannabinol appears to be therapeutic for nighttime agitation in severe dementia.Apr 30, 2006

E-cigarette and dual-product use are significantly associated with greater odds of reporting sleep-related complaints among adolescents.Aug 19, 2019

Effects of light-to-moderate intensity aerobic exercise on objectively measured sleep parameters among community-dwelling older people.Jan 12, 2021

Effects of tangerine essential oil on brain waves, moods, and sleep onset latency.Oct 20, 2020

Electromagnetic field emissions may downregulate the synthesis of beta trace protein, the key enzyme in the synthesis of prostaglandin D2 an endogenous sleep-promoting neurohormone in the brain.Aug 01, 2010

Electromagnetic field exposure exposure during waking modifies the EEG during subsequent sleep. Oct 20, 2000

Electronic cigarette use was associated with worse sleep health.Sep 03, 2019

Electronic equipment repairers, exposed to ELF-EMF, are at a risk of oxidative stress and sleep insufficiency, which could be explained by lower plasma melatonin levels and higher MDA levels. Sep 01, 2010

Energy drink intake had detrimental effects related to stress, sleep dissatisfaction, mood, and suicidality in combination with junk food consumption.Oct 12, 2016

Exposure to mobile phone radiation in talk mode markedly and significantly delays sleep latency in humans.Jun 21, 2007

Flotation therapy helped relieve participants stress, anxiety, depression and relief from long lasting pain, while increasing sleep quality and optimism levels. Dec 31, 2013

Food intake during the biological night may contribute to other health problems associated with short sleep duration.Nov 03, 2015

Fruit and vegetable consumption and their polyphenol content are inversely associated with sleep duration.Nov 19, 2018

Gut microbiome diversity is associated with sleep physiology in humans.Dec 31, 2018

Health care workers using MRIs reported a high prevalence of subjective symptoms associated with MRI exposure.Sep 01, 2015

Hericium erinaceus improves mood and sleep disorders in patients affected by overweight or obesity.Dec 31, 2018

High frequency of mobile phone use at baseline was a risk factor for mental health outcomes at 1-year follow-up among the young adultsJan 31, 2011

Homeopathic Passiflora Compose could be an alternative to the use of psychotropic drugs for first intention treatment of anxiety and sleep disorders.Jan 31, 2016

Hyperbaric oxygen therapy is safe and effective for the treatment of sleep disorders in children with cerebral palsy.Feb 28, 2017

In a study of 918 children, valerian and lemon balm reduced dyssomnia and restlessness symptoms from moderate/severe to mild or absent in most patients. Jun 01, 2006

Investigation on the health of people living near mobile telephone relay stations.Jun 30, 2002

Kiwifruit consumption before sleep improved sleep onset, duration, and efficiency in adult patients.Dec 31, 2010

Lavender essential oil increased quality of sleep and reduced level of anxiety in patients with coronary artery disease.Jul 26, 2015

Long-term exposures to particulate matter and nitrogen dioxide were associated with poor sleep quality.Jan 11, 2019

Lovastatin has an adverse effect on sleep efficiency and sleep stages.Dec 01, 1991

Low-dose melatonin for sleep disturbances in early-stage cirrhosis.Jul 31, 2020

Maternal bisphenol A exposure during early pregnancy might be related to sleep-related problems in preschool children.Oct 05, 2018

Metoprolol use has been associated with a worsening of sleep characteristics.Sep 01, 2008

Mindfulness meditation and exercise both improve sleep quality.May 21, 2020

Mobile phone electromagnetic field exposure during sleep reduced waking after sleep onset and affected heart rate variability.May 01, 2003

Mobile phone exposure interferes with sleep patterns in subjects with mobile phone-related symptoms.Sep 20, 2010

Mobile phone exposure may affect melatonin onset time.Feb 01, 2006

Music therapy increased the sleep quality of students.May 31, 2019

Night-time sleep disturbance is common in individuals suffering from chronic pain and may be further exacerbated by opioid treatment.Aug 21, 2016

Nurses consuming energy drinks report poorer sleep and higher stress.Apr 07, 2019

Older adults with moderate sleep complaints can improve self-rated sleep quality by initiating a regular moderate-intensity exercise program.Dec 14, 2009

Over use of internet and social networks via smart phones is related to poor sleep quality and quantity.Dec 31, 2015

Pineal calcification (DOC) might indicate a decrease of melatonin production, which consecutively might lead to a disturbed circadian rhythmicity in the sleep-wake cycle.Jun 30, 1998

Plasma vitamin D deficiency is associated with poor sleep quality and night-time eating at mid-pregnancy in Singapore.Mar 28, 2017

Possible effect of binaural beat combined With autonomous sensory meridian response for inducing sleepDec 31, 2018

Probiotics administration may improve psychological well-being by ameliorating aspects of mood and sleep quality.Dec 31, 2018

Sleep Disorders

View the Evidence:
157 Abstracts with Sleep Disorders Research