Breast Cancer: Triple Negative

Name	AC	CK
Sulforaphane	7	27
Curcumin	16	25
EGCG (Epigallocatechin gallate)	4	23
Folate: Dietary	1	10
Fruit: All	1	10
Vegetables: All	1	10
Vitamin C	8	10
Berberine	7	9
Lichens	5	9
Resveratrol	7	9
Ashwagandha	3	8
Genistein	4	8
Polyphenols	6	8
Cannabis	3	7
Parthenolide	6	7
Blueberry	3	6
Cannabidiol	5	6
Ginsenosides	5	6
Quercetin	4	6
Reishi Mushroom	5	6
Tocotrienol: Gamma	2	6
Apigenin	5	5
Bee Propolis	4	5
Burdock	4	5
Cabbage	1	5
Catechin	4	5
Citral	1	5
Cucurbitacin B	4	5
Flavonoids	3	5
Gingerol	4	5
Gold (nanoparticles)	4	5
Lemongrass	1	5
Luteolin	4	5
Mushrooms: All	3	5
Sea buckthorn	1	5
Sesamin	1	5
Caffeic acid phenethyl ester	3	4
Carrot	3	4
Cyanidin 3-glucoside	2	4
Deguelin	3	4
Huaier (Trametes robiniophila murr)	4	4
Melatonin	3	4
Mulberry	2	4
Pterostilbene	3	4
Shikonin	3	4
Thymoquinone	4	4
Vitamin D	4	4
6-Shogaol	2	3
Anthocyanins	2	3
Apples	2	3
Baicalein	2	3
Curry Leaves	2	3
Fig	2	3
Fisetin	2	3
Garlic	3	3
Isoliquiritigenin	2	3
Kaempferol	2	3
Naringenin	3	3
Piperlongumine	2	3
S-Adenosylmethionine (SAMe)	2	3
Wogonin	3	3
Adlay	2	2
Allspice	1	2
Arctigenin	2	2
Cannabinoids	2	2
Carnosic Acid	2	2
Carnosol	2	2
Crocin	1	2
Curcumol	1	2
Ellagic Acid	1	2
Eugenol	2	2
Fermented Foods and Beverages	1	2
Frankincense	2	2
Fucoxanthin	1	2
Gac	1	2
Green Tea	2	2
Honokiol	1	2
Indole-3-Carbinol	1	2
Lignans	2	2
Long Pepper	1	2
Lotus	2	2
Maitake Mushroom	1	2
Myricetin	2	2
Neem	2	2
Nettle	2	2
Noni	2	2
Oleocanthal	2	2
Palash	1	2
Phloretin	1	2
Pomegranate Peel	2	2
Shallot	1	2
Shemamruthaa	1	2
Silibinin	2	2
Tualang Honey	2	2
Ursolic Acid	2	2
Venom: Snake	2	2
Vitamin K2	2	2
Wasabi	1	2
Xanthohumol	2	2
Zerumbone	1	2
Amygdalin	1	1
Apple Pectin	1	1
Apple Polyphenols	1	1
Artichoke	1	1
Astragaloside	1	1
Bacopa	1	1
Beans: All	1	1
Bee Venom	1	1
Benzyl isothiocyanate	1	1
Betulinic acid	1	1
Black Tea	1	1
Bloodroot	1	1
Bromelain	1	1
Caffeic Acid	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Chamomile	1	1
Chickpea	1	1
Chili pepper	1	1
Chrysin	1	1
Citrus Peel	1	1
Cleavers	1	1
Cordyceps sinensis	1	1
Cucurbitacin E	1	1
Dandelion	1	1
Delphinidin	1	1
Delta-tetrahydrocannabinol (THC)	1	1
Diosgenin	1	1
Diosmin	1	1
Dragon Fruit	1	1
False Black Pepper	1	1
False Daisy	1	1
Flaxseed	1	1
Fucoidan	1	1
Gallic Acid	1	1
Grape	1	1
Guduchi	1	1
Gynostemma	1	1
Hawthorn	1	1
Hibiscus	1	1
Hydroxytyrosol	1	1
Isoflavones	1	1
Isothiocyanates	1	1
Justicia gendarussa	1	1
Kahweol	1	1
Kudzu	1	1
Legumes	1	1
Lemon Balm	1	1
Ligustrazine	1	1
Lime: Key	1	1
Mangiferin	1	1
Mango Seed	1	1
Manuka Honey	1	1
Medicinal Mushrooms	1	1
Moringa oleifera	1	1
Mung Bean	1	1
Nexrutine (Phellodendrom)	1	1
Nicotinamide	1	1
Nobiletin	1	1
Oleanolic acid	1	1
Oleuropein	1	1
Olive Oil	1	1
Paeoniflorin	1	1
Peach	1	1
Phellinus Linteus	1	1
Pine Needle	1	1
Piperine	1	1
Plum	1	1
Pomegranate	1	1
Psychedelics:All	1	1
Puerarin	1	1
Rhubarb	1	1
Riboflavin (Vitamin B-2)	1	1
Rice Bran	1	1
Rosemaric Acid	1	1
Rosemary	1	1
Ruta Graveolens	1	1
Silymarin	1	1
Soursop	1	1
Soy	1	1
Spikenard	1	1
Syrian rue	1	1
Tangeretin	1	1
Thistle	1	1
Thyme	1	1
Tocotrienol: Delta	1	1
Turmeric	1	1
Vitex negundo	1	1
Walnut	1	1
Water: Deep Sea	1	1
Water: Deuterium Depleted	1	1
Yoghurt	1	1

Name	AC	CK
Oral Contraceptives	2	30
Fructose	1	10
High Fructose Corn Syrup	1	10
Aluminum	1	5
Aluminum Chloride	1	5
Antiperspirants	1	5
Organochlorine pesticides	1	5
Bisphenol A	4	4
Morphine	1	2
Mouse Mammary Tumour Viruses (MMTV)	1	2
2,4-Dichlorophenoxyacetic acid	1	1
Bisphenol S	1	1
Tamoxifen	1	1

Name	AC	CK
Thermal Therapy: Far-Infrared	1	10
Hyperbaric Treatment	1	2
Breastfeeding	1	1
Heat Therapy	1	1
Ultrasound	1	1
Ultrasound therapy	1	1

Name	AC	CK
Radiotherapy	3	22
Chemotherapy	3	12
Assisted Reproductive Technique	1	2

Mangiferin inhibits cell migration and invasion in breast cancer.Feb 16, 2018

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Pubmed Data : Cytotechnology. 2018 Feb 17. Epub 2018 Feb 17. PMID: 29455393

Article Published Date : Feb 16, 2018

Study Type : In Vitro Study

Additional Links

Substances : Mangiferin

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Anti-metastatic

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Melatonin inhibits tunicamycin-induced COX-2 expression in MDA-MB-231 cells. Mar 31, 2015

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O. majorana may be a promising chemopreventive and therapeutic candidate against highly invasive triple negative p53 mutant breast cancer.Dec 31, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2013 ;8(2):e56649. Epub 2013 Feb 22. PMID: 23451065

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Marjoram

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Survivin Down-Regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Plant Extracts

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Parthenolide exerts cytotoxic effects on breast cancer stem-like cells.Apr 13, 2016

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Pubmed Data : Cell Death Dis. 2016 Apr 14 ;7:e2194. Epub 2016 Apr 14. PMID: 27077810

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Resveratrol prevents p53 aggregation in vitro and in breast cancer cells.Jun 25, 2018

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Pubmed Data : Pharmacogn Mag. 2015 Oct ;11(Suppl 2):S290-5. PMID: 26664017

Article Published Date : Sep 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Pine Needle

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Chemopreventive, Chemotherapeutic

Additional Keywords : Essential Oils, Selective Cytotoxicity

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Selected stone fruit genotypes can be added to the list of fruits with cytotoxic effects against breast cancer cells while not affecting normal cells.Nov 30, 2014

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Pubmed Data : BMC Complement Altern Med. 2017 Nov 28 ;17(1):503. Epub 2017 Nov 28. PMID: 29183371

Article Published Date : Nov 27, 2017

Study Type : In Vitro Study

Additional Links

Substances : Venom: Snake

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Antiproliferative , Cytotoxic

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The results may be a good set of preliminary data for designing animal studies on estrogenic effect of bisphenol A and antiestrogenic of selenium.Feb 09, 2020

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Pubmed Data : Biol Trace Elem Res. 2020 Feb 10. Epub 2020 Feb 10. PMID: 32040846

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These findings suggest Thymoquinone as a potential small molecular inhibitor of cancer growth and metastasis.Aug 13, 2015

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Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:7860456. Epub 2018 May 16. PMID: 29887909

Article Published Date : Dec 31, 2017

Study Type : In Vitro Study

Additional Links

Substances : Lemon Balm

Diseases : Breast Cancer: Triple Negative

Pharmacological Actions : Antiproliferative , Chemopreventive

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These results provide strong preclinical justification for combining cisplatin with eugenol as therapeutic approach for triple-negative breast cancers.Oct 25, 2017

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Pubmed Data : Mol Carcinog. 2017 Oct 26. Epub 2017 Oct 26. PMID: 29073729

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Pubmed Data : Biomedicines. 2019 Dec 5 ;7(4). Epub 2019 Dec 5. PMID: 31817440

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Pubmed Data : Altern Ther Health Med. 2015 Aug ;21 Suppl 2:46-54. PMID: 26308760

Article Published Date : Jul 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Turmeric

Diseases : Breast Cancer: Triple Negative , Colon Cancer

Pharmacological Actions : Chemopreventive, Chemotherapeutic

Additional Keywords : Dose Response, Hawaiian Turmeric, Increased Bioavailability, Plant Extracts

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Thymoquinone and paclitaxel combined act in synergy against triple negative breast cancer cells.Oct 25, 2015

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Pubmed Data : Tumour Biol. 2015 Oct 26. Epub 2015 Oct 26. PMID: 26500095

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Pubmed Data : Oncotarget. 2016 May 27. Epub 2016 May 27. PMID: 27248470

Article Published Date : May 26, 2016

Study Type : In Vitro Study

Additional Links

Substances : Cannabidiol

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Transient receptor potential vanilloid type-2 activation

Additional Keywords : Chemotherapeutic Synergy: Doxorubicin, Median Survival Time

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Tualang honey has significant anticancer activity against human breast and cervical cancer cell lines.Mar 31, 2011

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Pubmed Data : Food Chem Toxicol. 2011 Apr ;49(4):871-8. Epub 2010 Dec 16. PMID: 21167897

Article Published Date : Mar 31, 2011

Study Type : In Vitro Study

Additional Links

Substances : Tualang Honey

Diseases : Breast Cancer, Breast Cancer: Triple Negative , Cervical Cancer

Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-7 Activation , Caspase-9 Activation

[+]

Tualang honey may be a potential adjuvant to be used with TAM for reducing the dose of TAM and reducing TAM-induced adverse effects.Dec 31, 2012

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Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:989841. Epub 2013 Feb 13. PMID: 23476711

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Pubmed Data : Sci Rep. 2018 Mar 28 ;8(1):5306. Epub 2018 Mar 28. PMID: 29593282

Article Published Date : Mar 27, 2018

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Diseases : Breast Cancer, Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Chemopreventive

Additional Keywords : Apoptotic, Breast Cancer, Breast Cancer: Triple Negative, Chemopreventive, Vitamin C

[+]

Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer.Apr 07, 2019

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Pubmed Data : Chem Biol Interact. 2016 Oct 25 ;258:126-33. Epub 2016 Aug 25. PMID: 27567548

Article Published Date : Oct 24, 2016

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer: Triple Negative , Cancer Metastasis

Pharmacological Actions : Anti-metastatic, Interleukin-1 beta downregulation, NF-kappaB Inhibitor

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View the Evidence: 461 Abstracts with Breast Cancer: Triple Negative Research

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Luteolin suppresses androgen receptor-positive triple-negative breast cancer cell proliferation and metastasis.Dec 31, 2020

M. chamomilla extract can prevent the migration and invasion of MCF-7 and MDA-MB-468 cell lines.Dec 31, 2016

Major triterpenoids in Chinese hawthorn inhibited proliferation and induced apoptosis in MDA-MB-231 cancer cells.Jan 31, 2017

Mangiferin inhibits cell migration and invasion in breast cancer.Feb 16, 2018

Melatonin inhibits tunicamycin-induced COX-2 expression in MDA-MB-231 cells. Mar 31, 2015

Metabolites of fruiting bodies of Xylaria sp are a natural source of antibacterial and anticancer agents.Dec 31, 2014

Moringa oleifera extracts act as an anti-cancer agent by decreasing cell motility and colony formation in colorectal and breast cancer cell lines.Dec 31, 2014

Myricetin could induce apoptosis in triple-negative breast cancer cells.May 05, 2018

Naringenin can inhibit the growth capacity of breast cancer cells MDA-MB-231 and block the migration and invasion of breast cancer cells MDA-MB-231.Feb 28, 2015

naringenin caused an inhibitory effect on MDA-MB-231 cells via induction of apoptosis.Dec 31, 2018

Naringenin inhibits migration of breast cancer cells via inflammatory and apoptosis cell signaling pathways.Apr 01, 2019

Neem seed oil inhibits the growth of human breast cancer cells.Jan 26, 2017

Neferine inhibits MDA-MB-231 cells growth and metastasis by regulating miR-374a/FGFR-2.Jun 14, 2019

Nettle extract substantially increased sensitivity of breast cancer cells to paclitaxel.Aug 04, 2016

Nexrutine may provide a novel approach for protection against breast cancer. Dec 31, 2013

Nicotinamide may be used as a chemo or radiosensitizing agent regardless of the BRCA1 status in breast cancer.Jan 31, 2015

Nobiletin bioactivation in MDA-MB-468 breast cancer cells by cytochrome P450 CYP1 enzymes.Feb 28, 2018

Nobiletin had antiproliferative and apoptosis inducing actions in triple negative breast cancer cells.Mar 31, 2014

Noni extracts strongly inhibited the proliferation and increased apoptosis in MCF-7 and MDA-MB-231 cells.Jul 08, 2015

Novel mechanism of cannabidiol-induced apoptosis in breast cancer cell lines.Jun 21, 2018

O. majorana may be a promising chemopreventive and therapeutic candidate against highly invasive triple negative p53 mutant breast cancer.Dec 31, 2012

Oleanolic acid could act as a chemopreventive agent in human breast cancer and could inhibit the proliferation of highly invasive breast cancer cells.Dec 31, 2014

Oleocanthal inhibits proliferation and migration by modulating Ca2+ entry through TRPC6 in breast cancer cells.Dec 31, 2018

Oleocanthal selectively and rapidly induces cell death in cancer cells without being cytotoxic to non-cancerous cellsDec 31, 2014

Oleocanthal treatment caused a marked downregulation of phosphorylated mTOR in metastatic breast cancer cell line (MDA-MB-231).Aug 06, 2015

Oleuropein induces apoptosis via abrogating NF-κB activation cascade in estrogen receptor-negative breast cancer cells.Feb 28, 2019

Oridonin combined with capecitabine can synergistically inhibit the proliferation of MDA-MB-231 human breast cancer cells.Dec 11, 2017

Our findings highlight TIMP-3 induction as a key epigenetic event modulated by GTPs in restoring the MMP:TIMP balance to delay breast cancer progression and invasion.May 31, 2015

Our results indicate that Xanthoria parietina is a major potential source of antimicrobial and anticancer substances. Dec 31, 2014

Overexpression of RIP3 sensitizes MCF-7 and MDA-MB-231 breast cancer cells to parthenolide in vitro.Jun 30, 2014

Parthenolide could be a novel candidate for cancer treatment.Dec 31, 2018

Parthenolide exerts cytotoxic effects on breast cancer stem-like cells.Apr 13, 2016

Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells.Nov 30, 2013

Parthenolide lowers the viability of MDA-MB-231 breast cancer cells.Jun 30, 2014

Parthenolide prevents resistance of MDA-MB231 cells to doxorubicin and mitoxantrone.Dec 31, 2016

Peganum harmala's extract decreases the growth rate of the cancer cell line through inducing apoptosis.Nov 30, 2015

Pelingo apple is rich in food components that can markedly inhibit in vitro tumorigenesis and growth of human breast cancer cells.Dec 31, 2014

Pepper seed extract inhibits invasion and migration of breast cancer cells.Dec 31, 2013

Phellinus linteus extracts synergized with low doses of 5-FU to inhibit triple-negative breast cancer cell growth.Dec 31, 2014

Phenethyl isothiocyanate suppresses stemness in the chemo- and radio-resistant triple-negative breast cancer cells.Jan 21, 2020

Phenolic fractions from Muscadine grape "Noble" pomace can inhibit breast cancer cell MDA-MB-231 better than those from European grape.Mar 21, 2017

Phoenix Dan Cong tea may act as a substitute for natural antioxidants and as a promising anticancer agent due to its protective effect on human health.Dec 31, 2017

Phosphoproteomic analysis of the antitumor effects of ginsenoside Rg3 in human breast cancer cells.Feb 28, 2018

Physodic acid and acetone extract from H. physodes displayed cytotoxic effects in the breast cancer cell lines.Oct 31, 2016

Phytochemicals inhibit migration of triple negative breast cancer cells by targeting kinase signaling.Jan 01, 2020

Piperine inhibits the growth and motility of triple-negative breast cancer cells.Jan 31, 2015

Piperlongumine and immune cytokine TRAIL synergize to promote tumor death.Dec 31, 2014

Pleurotus highking mushrooms potentiate antiproliferative and antimigratory activity against triple-negative breast cancer cells.Dec 31, 2019

Pluronic F68-curcumin conjugate micelles are promising to improve the clinical effectiveness of CUR in cancer treatment.Jun 11, 2015

Polyphenols extracted from Artemisia annua exhibit anti-cancer effects on radio-resistant MDA-MB-231 human breast cancer cells.Apr 20, 2020

Pomegranate peel extract inhibits expression of β-catenin, epithelial mesenchymal transition, and metastasis in triple negative breast cancer cells.May 29, 2018

Possible beneficial effects of N-acetylcysteine for treatment of triple-negative breast cancer.Jan 23, 2021

Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine.Dec 31, 2020

Protein fraction from Withania somnifera induces ROS-dependent mitochondria-mediated apoptosis in human MDA-MB-231 breast cancer cells.May 19, 2019

Proteomic identification of eEF1A1 as a molecular target of curcumol for suppressing metastasis of MDA-MB-231 cells.Apr 11, 2017

Pterostilbene enhances TRAIL-induced apoptosis in TRAIL-resistance triple negative breast cancer cells.Dec 26, 2017

Pu-erh tea water extract inhibits cell proliferation of MDA-MB-231 cells through the induction of apoptosis and the stimulation of cell cycle arrest.Dec 31, 2016

quercetin may inhibit triple negative breast cancer metastasis and also improve the therapeutic efficacy of existing chemotherapeutic drugs. May 11, 2015

Reishi may be a potential natural inhibitor for breast cancer.Apr 16, 2017

Reishi mushroom can inhibit breast-to-lung cancer metastases through the downregulation of genes responsible for cell invasiveness.May 31, 2014

Resveratrol and pterostilbene significantly inhibit the proliferation of both MDA-MB-157 and HCC1806 breast cancer cells.Dec 31, 2014

Resveratrol prevents p53 aggregation in vitro and in breast cancer cells.Jun 25, 2018

resveratrol sensitizes breast cancer cells to respond to UV treatment as a natural bioactive compound.May 31, 2017

Rosemary/carnosic acid, alone or combined with curcumin, may be useful to prevent and treat ER-negative breast cancer.Sep 30, 2012

Rosmarinic acid can inhibit the proliferation, migration and induce apoptosis of MDA-MB-231 cells.Jul 31, 2018

S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells.Dec 31, 2017

Sanguinarine as a potent inhibitor of dihydrofolate reductase, able to impair enzyme activity even in methotrexate resistant MDA-MB-231 cells.Jul 31, 2014

Scots pine needles extract exhibits some potential as a chemopreventive or chemotherapeutic agent for unresponsive breast cancer.Sep 30, 2015

Selected stone fruit genotypes can be added to the list of fruits with cytotoxic effects against breast cancer cells while not affecting normal cells.Nov 30, 2014

Sensitization of MDA-MBA231 breast cancer cell to docetaxel by myricetin loaded into biocompatible lipid nanoparticles.Aug 01, 2019

Several pomegranate phytochemicals exhibited synergistic effects in suppressing growth of tumor cells.Dec 31, 2014

Shikonin inhibits cell growth and induces apoptosis in different types of breast cancer cells.Feb 07, 2018

View the Evidence:
461 Abstracts with Breast Cancer: Triple Negative Research

Neferine inhibits MDA-MB-231 cells growth and metastasis by regulating miR-374a/FGFR-2.Jun 14, 2019