Aging Skin

Name	AC	CK
Soy	8	45
Alpha-Lipoic Acid	2	30
Vitamin E	5	23
Zinc	4	23
Flavonoids	4	22
Vitamin C	4	22
Catechin	2	21
Green Tea	3	21
Aloe Vera	1	20
Blueberry	2	20
Fish extract	2	20
Ginkgo biloba	2	20
Pycnogenol (Pine Bark)	2	20
Genistein	3	14
Pomegranate	5	14
Flaxseed	2	12
Echinacea	2	11
Grape Seed Extract	2	11
Tomato	2	11
Vegetables: All	2	11
White Tea	2	11
Amino Acids	1	10
Beta-glucan	1	10
Chamomile	1	10
Chocolate	1	10
Corni Fructus	1	10
Fig	1	10
Frankincense	1	10
Ginseng	1	10
Glycosaminoglycans	1	10
Green Tea (topical)	1	10
Horse Chestnut	1	10
Isoflavones	1	10
Multivitamin	1	10
Pine Bark Extract	1	10
Selenium	1	10
Silica: Orthosilicic acid	1	10
Torilus Fructus	1	10
Turmeric	1	10
Unspecified Species	1	10
White Mulberry	1	10
X-xyloside	1	10
Myricetin	2	6
Sulforaphane	4	6
Curcumin	2	5
Oleuropein	3	5
Resveratrol	5	5
Boswellia	1	4
Broccoli	2	4
Creatine	1	4
Polyphenols	3	4
Sprouts	2	4
Cocoa	2	3
Olive leaf extract	2	3
Amla Fruit	1	2
Apigenin	1	2
Artichoke	1	2
Banana	1	2
Bifidobacterium Breve	1	2
Chaga Mushroom (Inonotus obliquus)	1	2
EGCG (Epigallocatechin gallate)	1	2
Ghee	1	2
Ginseng (Korean)	1	2
Kaempferia parviflora	1	2
Melatonin	1	2
Molasses	1	2
Phyllanthus emblica	1	2
Rosemary	2	2
Royal Jelly	1	2
Shorea robusta	1	2
Vitamin D	1	2
beta-Carotene	1	2
Acerola	1	1
Antioxidant formulas	1	1
Astaxanthin	1	1
Astragalus	1	1
Black Poplar	1	1
Blackberry	1	1
Coconut oil: topical	1	1
Cork Extract	1	1
Date Kernel Extract	1	1
Dill	1	1
Ellagic Acid	1	1
Fermented Foods and Beverages	1	1
Fruit: All	1	1
Glycyrrhizin	1	1
Krameria lappacea: topical	1	1
Kudzu	1	1
NAC (N-acetyl-L-cysteine)	1	1
Natto	1	1
Olive oil: topical	1	1
Orange	1	1
Peanut oil: topical	1	1
Peony	1	1
Rose	1	1
Rutin	1	1
Sesame oil: topical	1	1
Sesamol	1	1
Tea	1	1
Terminalia	1	1
Terminalia Chebula Gall Extract	1	1
Burdock	1	0

Name	AC	CK
Tobacco: Smoking	1	20
Corticosteroid	1	3
Prednisone	1	3
Parabens	1	1

Name	AC	CK
Light-Emitting Diodes (LEDs) Therapy	2	11
Light Therapy	2	2
Light Therapy: Colored	1	1
Light Therapy: Red Colored	1	1
Sunlight exposure	1	1

[+]

A combination of green tea and ginkgo biloba extracts effectively improved skin conditions and the improvement of skin elasticity.Aug 31, 2014

Click here to read the entire abstract

Pubmed Data : J Drugs Dermatol. 2014 Sep ;13(9):1092-7. PMID: 25226010

Article Published Date : Aug 31, 2014

Pubmed Data : J Cosmet Dermatol. 2009 Jun;8(2):147-51. PMID: 19527341

Pubmed Data : Arch Dermatol Res. 2005 Oct;297(4):147-53. Epub 2005 Oct 26. PMID: 16205932

Article Published Date : Oct 01, 2005

Study Type : Human Study

Additional Links

Substances : Silica: Orthosilicic acid

Diseases : Aging Skin, Hair Quality Problems, Nail Diseases

[+]

Continuous administration of apple polyphenol for 12 weeks alleviated ultraviolet irradiation induced skin pigmentation.Apr 12, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2020 Apr 13 ;12(4). Epub 2020 Apr 13. PMID: 32294883

Article Published Date : Apr 12, 2020

Study Type : Human Study

Additional Links

Substances : Apple Polyphenols

Diseases : Skin Diseases: Photo-Aging, Ultraviolet Radiation Induced Damage

Pharmacological Actions : Photoprotective

[+]

Pharmacological Actions : Dermatologic Agents

Additional Keywords : Plant Extracts

[+]

Horse chestnut extract exhibits potent anti-aging properties in human skin.Sep 01, 2006

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Pubmed Data : J Cosmet Sci. 2006 Sep-Oct;57(5):369-76. PMID: 17111071

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Skinmed. 2010 Jan-Feb;8(1):23-9. PMID: 20839421

Article Published Date : Jan 01, 2010

Study Type : Human Study

Additional Links

Diseases : Aging Skin, Nicotine/Tobacco Toxicity , Wrinkles, Aging Skin

Problem Substances : Tobacco: Smoking

[+]

Soy extract appears to rejuvenate the structure of mature skin.Nov 01, 2004

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Pubmed Data : J Pediatr Gastroenterol Nutr. 2004 Nov;39(5):487-92. PMID: 15623355

Article Published Date : Nov 01, 2004

Study Type : Human Study

Additional Links

Substances : Genistein, Soy

Diseases : Aging Skin

Additional Keywords : Plant Extracts

[+]

Supplementation with fermented honeybush could be helpful for protecting against skin aging.Sep 30, 2018

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Pubmed Data : J Cosmet Laser Ther. 2018 Oct ;20(5):313-318. Epub 2018 Feb 1. PMID: 29388846

Article Published Date : Sep 30, 2018

Study Type : Human Study

Additional Links

Substances : Rooibos

Diseases : Aging Skin

Pharmacological Actions : Antioxidants

Additional Keywords : Phytotherapy, Plant Extracts

[+]

The combined formulation of fruit extracts showed excellent antioxidative and anti-collagenase activity as well as a significant effect on anti-wrinkle activity on human skin.Dec 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Cosmet Investig Dermatol. 2015 ;8:389-96. Epub 2015 Jul 16. PMID: 26203268

Yarrow promotes skin resurfacing and improves the appearance of wrinkles and pores.Dec 01, 2011

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Pubmed Data : Int J Cosmet Sci. 2011 Dec ;33(6):535-42. Epub 2011 Jun 29. PMID: 21711463

Additional Keywords : Plant Extracts

[+]

Cold-pressed perilla oil has therapeutic potential in terms of protecting against skin photo-aging.Feb 21, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2020 Feb 22 ;25(4). Epub 2020 Feb 22. PMID: 32098445

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Pubmed Data : J Neuroimmunol. 2009 Dec 10;217(1-2):28-37. Epub 2009 Sep 30. PMID: 18254806

Article Published Date : Dec 10, 2009

Study Type : Animal Study

Additional Links

Substances : Creatine

Diseases : Aging Skin, DNA damage, Skin Diseases: Photo-Aging, Wound Healing

Pharmacological Actions : Dermatologic Agents

[+]

Pubmed Data : Phytother Res. 2008 Mar;22(3):323-9. PMID: 20093107

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Myricetin

Diseases : Aging Skin, Skin Diseases: Photo-Aging

[+]

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2006 Aug 28;240(2):243-52. Epub 2005 Nov 3. PMID: 16271437

Article Published Date : Aug 28, 2006

[+]

Anti‑wrinkle effect of fermented black ginseng on human fibroblasts.Feb 28, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Med. 2017 Mar ;39(3):681-686. Epub 2017 Jan 16. PMID: 28098856

Article Published Date : Feb 28, 2017

Study Type : In Vitro Study

Additional Links

Substances : Ginseng

Diseases : Aging Skin, Wrinkles

Pharmacological Actions : Antioxidants, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Additional Keywords : Plant Extracts

[+]

Artichoke extract improved the expression of genes involved in anti-ageing mechanisms.Oct 22, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2018 Oct 23 ;23(11). Epub 2018 Oct 23. PMID: 30360471

Pubmed Data : J Invest Dermatol. 2012 Aug 30. Epub 2012 Aug 30. PMID: 22931923

Article Published Date : Aug 29, 2012

Study Type : Review

Additional Links

Diseases : Aging Skin

Therapeutic Actions : Light Therapy

[+]

buckwheat extract has antioxidant and photoprotective properties.Mar 01, 2006

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2018 Jun 9 ;19(6). Epub 2018 Jun 9. PMID: 29890746

Article Published Date : Jun 08, 2018

Study Type : In Vitro Study

Additional Links

Diseases : Aging Skin

Additional Keywords : Exosomes

[+]

Extraction conditions for Rosa gallica petal extracts with anti-skin aging activities.Sep 30, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Photochem Photobiol B. 2012 Jan 5 ;106:24-33. Epub 2011 Oct 20. PMID: 22070900

Article Published Date : Jan 04, 2012

Study Type : In Vitro Study

Additional Links

Substances : Hydrogen Water

Diseases : Aging Skin, DNA damage, Oxidative Stress, Ultraviolet Radiation Induced Damage

Therapeutic Actions : Sunlight exposure

Pharmacological Actions : Anti-Apoptotic, Antioxidants

[+]

Identification of chia seed peptides with enzyme inhibition activity towards skin-aging enzymes.Jul 31, 2020

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Pubmed Data : Amino Acids. 2020 Aug ;52(8):1149-1159. Epub 2020 Jul 30. PMID: 32734432

Click here to read the entire abstract

Pubmed Data : J Photochem Photobiol B. 2017 May 12 ;172:42-51. Epub 2017 May 12. PMID: 28527426

[+]

Plant polyphenols may be useful in skin diseases associated with solar UV radiation-induced inflammation, oxidative stress and DNA damage. Nov 07, 2009

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Pubmed Data : Arch Dermatol Res. 2009 Nov 7. PMID: 19898857

Article Published Date : Nov 07, 2009

Study Type : Commentary

Additional Links

Substances : Polyphenols

Diseases : Aging Skin, Skin Diseases: Photo-Aging

[+]

Plant stem cells as innovation in cosmetics.Aug 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Acta Pol Pharm. 2014 Sep-Oct;71(5):701-7. PMID: 25362798

Article Published Date : Aug 31, 2014

Pubmed Data : Biofactors. 2007;30(2):129-38. PMID: 18356584

Article Published Date : Jan 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Orange

Diseases : Skin Diseases: Photo-Aging, Sunburn

Pharmacological Actions : Apoptotic

Additional Keywords : Plant Extracts

[+]

Resveratrol and NAC may prevent age-associated decline in skin and/or connective tissue quality.Jun 01, 2010

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Pubmed Data : Minerva Ginecol. 2010 Jun;62(3):195-201. PMID: 20595944

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Pubmed Data : J Sci Food Agric. 2020 Jan 30 ;100(2):672-681. Epub 2019 Nov 15. PMID: 31583701

Article Published Date : Jan 29, 2020

Study Type : In Vitro Study

Additional Links

Substances : Hibiscus sabdariffa

Diseases : Aging Skin, Photooxidative Stress

Therapeutic Actions : Sunlight exposure

Pharmacological Actions : Antioxidants

Additional Keywords : Plant Extracts

[+]

Review: natural approaches to reduce skin aging.Jun 01, 2008

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Pubmed Data : Acta Dermatovenerol Alp Panonica Adriat. 2008 Jun;17(2):47-54. PMID: 18709289

Article Published Date : Jun 01, 2008

Study Type : Review

Additional Links

Substances : Antioxidant formulas, Fruit: All, Vegetables: All

Diseases : Aging Skin

[+]

Rosmarinic acid has protective properties against UV and other ionizing radiations.Feb 01, 2009

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Pubmed Data : Food Chem Toxicol. 2009 Feb;47(2):386-92. Epub 2008 Nov 30. PMID: 19084569

Article Published Date : Feb 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Rosemary

Diseases : DNA damage, Radiation Induced Illness, Skin Cancer, Skin Diseases: Photo-Aging

Pharmacological Actions : Antioxidants, Radioprotective

Additional Keywords : Plant Extracts

[+]

Sesamol prevents UVB-induced damage to cultured skin cells. Dec 01, 2010

Click here to read the entire abstract

Pubmed Data : Arch Dermatol Res. 2010 Dec ;302(10):733-44. Epub 2010 Aug 10. PMID: 20697726

Article Published Date : Dec 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Sesamol

Diseases : DNA damage, Lipid Peroxidation, Oxidative Stress, Skin Diseases: Photo-Aging

Pharmacological Actions : Antioxidants, Apoptotic, Superoxide Dismutase Up-regulation

[+]

Skin aging can be decelerated with a nutrient complex containing soy, tomato, grape seed, and white tea extracts, and sodium ascorbate (vitamin C), tocopherol acetate (vitamin E), zinc, and Biomarine complex. Apr 01, 1997

Click here to read the entire abstract

Pubmed Data : Gastroenterol Hepatol. 1997 Apr;20(4):172-4. PMID: 17028931

Article Published Date : Apr 01, 1997

Study Type : In Vitro Study

Additional Links

Substances : Grape Seed Extract, Soy, Tomato, Vitamin C, Vitamin E, White Tea, Zinc

Diseases : Aging, Aging Skin

[+]

Sulforaphane has a potential use as a compound for protection against UVB-induced skin inflammation.Aug 01, 2010

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View the Evidence: 167 Abstracts with Aging Skin Research

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A combination of green tea and ginkgo biloba extracts effectively improved skin conditions and the improvement of skin elasticity.Aug 31, 2014

A moisturizer containing compounds found within soy is safe and effective in preventing photoaging. Sep 01, 2007

A multi-nutrient mixture of marine proteins, alpha-lipoic acid, pine bark extract, vitamins and minerals is safe and efficacious in the treatment of aging symptoms of the skin in women. May 01, 2005

A multi-nutrient mixture of soy extract, fish protein polysaccharides, extracts from white tea, grape seed and tomato, vitamins C and E as well as zinc and chamomile extract improves signs of skin aging in post-menopausal women. Oct 01, 2006

A multi-nutrient mixture of vitamin C, vitamin E, carotenoids, selenium, zinc, amino acids and glycosaminoglycans, blueberry extract and pycnogenol improves visible signs of ageing in women 45-73 years of age. Jul 01, 2004

A topical cream containing 5% alpha-lipoic acid improves clinical symptoms of photoageing of facial skin. Oct 01, 2003

A topical product containing C-xyloside and blueberry extract improves the appearance of type II diabetic skin.Jun 01, 2009

Aloe gel significantly improves wrinkles and elasticity in photoaged human skin.Feb 01, 2009

Application of melatonin cream 12.5% protects against natural sunlight induced erythema.Aug 08, 2016

Assessment of the effect of extract formulation of date palm kernel on facial skin wrinkles.Dec 31, 2018

Association of dietary fat, vegetables and antioxidant micronutrients with skin ageing in Japanese women.May 01, 2010

Choline-stabilized orthosilicic acid has a positive effect on skin surface and skin mechanical properties, and on brittleness of hair and nails. Oct 01, 2005

Continuous administration of apple polyphenol for 12 weeks alleviated ultraviolet irradiation induced skin pigmentation.Apr 12, 2020

Continuous astaxanthin consumption produces a strong antioxidant effect resulting in facial skin rejuvenation.Nov 30, 2017

Daily almond consumption may reduce wrinkle severity in postmenopausal females to potentially have natural anti-aging benefits.Sep 30, 2019

Echinacea improves skin in a dermatologial application.Apr 01, 2010

Enzyme-treated red ginseng extract significantly improved eye wrinkle roughness, skin elasticity, and moisture content of skin. Jun 30, 2016

Evaluation of the effectiveness and safety of peppermint peel soft peeling for skin ageing.Oct 31, 2019

Exogenous melatonin reverses the enhanced oxidative damage to membrane lipids and improves skin biophysical characteristics in former-smokers.Dec 22, 2017

Flaxseed oil diminishes skin sensitivity and improves skin barrier function and condition.Nov 18, 2010

Green tea extracts have a protective effect on photoaging and photoimmunosuppression. Aug 01, 2009

Green tea supplementation results in histological improvement in elastic tissue content in photo-aged skin. Jul 01, 2005

Horse chestnut extract exhibits potent anti-aging properties in human skin.Sep 01, 2006

Hot water extract of Hydrangea serrata leaves could be used as a health supplement for skin anti-aging.May 27, 2020

Intense pulsed light therapy has a skin rejuvenating effect in human subjects. Aug 01, 2006

Light-emitting diodes (LED) therapy has a skin rejuvenating effect in human subjects.Jul 27, 2007

Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women.Jun 01, 2006

Long-term prophylactic astaxanthin supplementation may inhibit age-related skin deterioration.Jun 30, 2017

Oral administration of French maritime pine bark extract (Flavangenol(®)) improves clinical symptoms in photoaged facial skin.Dec 31, 2011

Oral intake of soy isoflavone aglycone improves the aged skin of adult women.Feb 01, 2007

Protective effects of a topical antioxidant mixture against ultraviolet-induced photodamage in human skin.Nov 30, 2008

Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity. Dec 31, 2011

Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin.Dec 01, 2009

Regular consumption of a chocolate rich in flavanols confers significant photoprotection and can thus be effective at protecting human skin from harmful UV effects.Sep 01, 2009

Smoking cessation improves skin quality. Jan 01, 2010

Soy extract appears to rejuvenate the structure of mature skin.Nov 01, 2004

Supplementation with fermented honeybush could be helpful for protecting against skin aging.Sep 30, 2018

The combined formulation of fruit extracts showed excellent antioxidative and anti-collagenase activity as well as a significant effect on anti-wrinkle activity on human skin.Dec 31, 2014

The results suggest that continued Aloe sterol ingestion contributes to maintaining healthy skin.Dec 31, 2015

These data suggest the possibility that topical DHEA could be used as an efficient and physiological antiageing skin agent.Oct 31, 2010

These findings are preliminary confirmation of the anti-aging benefit to the skin of L. plantarum HY7714 as a nutricosmetic agent.Dec 27, 2015

This study compares the anti-aging potential of ginkgo biloba and topical tea preparations.Apr 01, 2010

Topical application of boswellic acids may represent a suitable treatment option for selected features of skin photoaging.Dec 31, 2009

Turmeric extract supplementation prevents UVB-induced skin aging. Jul 03, 2009

Fennel is a potential botanical agent for the treatment of skin damage induced by UV irradiation.Nov 14, 2016

Phytochemicals rosmarinic acid, ampelopsin, and amorfrutin-A can modulate Age-related phenotype of serially passaged human skin fibroblasts in vitro.Jan 01, 2019

Skin protective activity of silymarin and its flavonolignans.Mar 13, 2019

These results demonstrate that air pollution contributes to skin inflammation and skin aging via impaired collagen synthesis.Sep 11, 2018

Wild chrysanthemum extract prevents UVB radiation-induced acute cell death and photoagingFeb 29, 2016

Yarrow promotes skin resurfacing and improves the appearance of wrinkles and pores.Dec 01, 2011

Spontaneous skin tearing during systemic corticosteroid treatment has been reported.Mar 28, 1980

A traditional Indian medical formula containing clarified butter (ghee), flax seed oil, amla (P. emblica fruits), Shorea robusta resin and zinc (Yashada bhasma) stimulates wound healing and tissue regeneration. Feb 27, 2009

All these findings suggest that EGCG can resist skin senility effectively.Mar 22, 2017

Anthocyanins rich pomegranate cream as a topical formulation with anti-aging activity.Feb 04, 2020

Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo.Jun 05, 2016

Beta-carotene protects against ozone induced skin oxidative stress which is consistent with its protective role on skin. May 01, 2009

Bifidobacterium breve supplementation has a photoprotective effect against skin damage induced by ultraviolet irradiation in hairless mice.Nov 30, 2012

Broccoli sprouts contain compounds which protect the skin against damage by UV radiation. Oct 30, 2007

Cacao extract may offer a protective effects against photo-aging.Feb 04, 2016

Chrysanthemum indicum was a novel photo-protective agent from natural resources against UV irradiation.Sep 30, 2015

Cold-pressed perilla oil has therapeutic potential in terms of protecting against skin photo-aging.Feb 21, 2020

Effects of topical application of patchouli alcohol on the UV-induced skin photoaging in mice.Oct 14, 2014

EGCG, a green tea polyphenol, prevents photocarcinogenesis in mice by enhancing DNA repair. May 15, 2006

Ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation.Jul 31, 2010

Folic acid and creatine significantly accelerates epidermal skin regeneration in vitro and in vivo.Dec 10, 2009

Genistein aglycone might be an effective alternative therapy for the management of age-related skin changes in postmenopausal women.Jan 31, 2012

Hawthorn polyphenol extract inhibits UVB-induced skin photoaging.Aug 14, 2018

Hydrangea serrata extract attenuate UVB-induced photoaging. Feb 28, 2019

I. obliquus can prevent the aging process by attenuating oxidative stress in a model of stress-induced premature senescence.Apr 30, 2011

Korean ginseng extract inhibits UVB irradiation-induced skin aging in hairless mice. Jun 25, 2009

Korean red ginseng is an excellent skin whitening and anti-aging product.Apr 30, 2020

Aging Skin

View the Evidence:
167 Abstracts with Aging Skin Research