Results for Chemotherapeutic

A comprehensive review on anticancer mechanisms of crocin.

Article Published Date : Jul 02, 2017
Study Type : Review
Additional Links
Substances : Crocin : CK(117) : AC(62)
Diseases : Cancers: All : CK(22165) : AC(7896)
Pharmacological Actions : Anti-metastatic : CK(1284) : AC(927), Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Chemotherapeutic : CK(397) : AC(152), Telomerase Inhibitor : CK(55) : AC(35)
Additional Keywords : Anti-metastatic, Antiproliferative : CK(65) : AC(52), Apoptotic, Cancers: All, Chemotherapeutic, Crocin, Telomerase Inhibitor

A treatment approach including intravenous α-lipoic acid and low-dose naltrexone led to stable disease in this patient.

Article Published Date : Nov 30, 2017
Study Type : Human: Case Report
Additional Links
Substances : Alpha-Lipoic Acid : CK(785) : AC(168), Vitamin C: Intravenous : CK(147) : AC(25)
Diseases : Kidney Cancer : CK(213) : AC(79)
Pharmacological Actions : Chemopreventive : CK(4220) : AC(1326), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Alpha-Lipoic Acid, Chemopreventive, Chemotherapeutic, Kidney Cancer, Vitamin C: Intravenous

Arctigenin results in autophagic cell death and decreased ER expression in ER-positive human breast cancer cells.

Article Published Date : Feb 08, 2018
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin : CK(16) : AC(11)
Diseases : Breast Cancer : CK(5066) : AC(1738)
Pharmacological Actions : Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Arctigenin, Breast Cancer : CK(2) : AC(1), Chemotherapeutic, Natural Substance/Drug Synergy : CK(352) : AC(142)

Genistein intake mimicking Asian consumption patterns improved response of mammary tumors to tamoxifen therapy.

Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Genistein : CK(650) : AC(296)
Diseases : Breast Cancer : CK(5066) : AC(1738)
Pharmacological Actions : Chemotherapeutic : CK(397) : AC(152), Immunomodulatory : CK(2249) : AC(733)
Additional Keywords : Breast Cancer : CK(2) : AC(1), Chemotherapeutic, Gene Expression Regulation : CK(431) : AC(214), Genistein, Immunomodulatory

Iscador Qu inhibits doxorubicin-induced senescence of MCF7 cells.

Article Published Date : Jun 18, 2017
Study Type : In Vitro Study
Additional Links
Substances : Mistletoe : CK(87) : AC(23)
Diseases : Breast Cancer : CK(5066) : AC(1738)
Pharmacological Actions : Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Breast Cancer : CK(2) : AC(1), Chemotherapeutic, Chemotherapeutic Synergy: Doxorubicin : CK(91) : AC(61), Mistletoe

Low-molecular-weight fucoidan combined with chemotarget agents significantly improved the disease control rate.

Article Published Date : Apr 20, 2017
Study Type : Human Study
Additional Links
Substances : Fucoidan : CK(401) : AC(228)
Diseases : Colorectal Cancer : CK(2874) : AC(1192)
Pharmacological Actions : Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Chemotherapeutic, COLORECTAL CANCER, Fucoidan

Melatonin could be used as an adjuvant agent with rapamycin in head and neck cancers.

Article Published Date : Dec 15, 2017
Study Type : In Vitro Study
Additional Links
Substances : Melatonin : CK(1399) : AC(461)
Diseases : Head and Neck Cancer : CK(374) : AC(85)
Pharmacological Actions : Chemoprotective Agents : CK(356) : AC(146), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Chemoprotective Agents, Chemotherapeutic, Head and Neck Cancer, melatonin, Natural Substance/Drug Synergy : CK(352) : AC(142)

Neferine augments the therapeutic efficacy of cisplatin in human lung adenocarcinoma cells.

Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(153) : AC(108)
Diseases : Lung Cancer : CK(1741) : AC(742)
Pharmacological Actions : Autophagy Up-regulation : CK(296) : AC(197), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Autophagy Up-regulation, Chemotherapeutic, Chemotherapeutic Synergy: Cisplatin : CK(137) : AC(103), Lotus, lung cancer

Neferine revealed higher toxicity toward paclitaxel and doxorubicin-resistant breast, lung or colon cancer cells.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(153) : AC(108)
Diseases : Breast Cancer : CK(5066) : AC(1738), Cancers: Multi-Drug Resistant : CK(121) : AC(94), Colon Cancer : CK(1217) : AC(742), Lung Cancer : CK(1741) : AC(742)
Pharmacological Actions : Chemosensitizer : CK(772) : AC(577), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Breast Cancer : CK(2) : AC(1), Cancers: Multi-Drug Resistant, Chemosensitizer, Chemotherapeutic, COLON CANCER, Lotus, lung cancer

Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa).

Article Published Date : Sep 30, 2016
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed) : CK(934) : AC(279)
Pharmacological Actions : Analgesics : CK(2569) : AC(470), Anti-Inflammatory Agents : CK(12461) : AC(4729), Anticonvulsants : CK(534) : AC(146), Antihypertensive Agents : CK(2852) : AC(424), Antimicrobial : CK(776) : AC(352), Antioxidants : CK(14410) : AC(5758), Chemotherapeutic : CK(397) : AC(152), Hypoglycemic Agents : CK(3297) : AC(841), Hypolipidemic : CK(3189) : AC(707)
Additional Keywords : Analgesics, Anti-Inflammatory Agents, Anticonvulsants, Antihypertensive Agents, Antimicrobial, Antioxidants : CK(1) : AC(1), Chemotherapeutic, Nigella sativa (aka Black Seed), Plant Extracts : CK(11762) : AC(4236)

Structural optimization of mangiferin binding to cancer molecular targets.

Article Published Date : Mar 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Mangiferin : CK(179) : AC(106)
Diseases : Cancers: All : CK(22165) : AC(7896)
Pharmacological Actions : Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Cancers: All, Chemotherapeutic, Mangiferin

These results suggest fisetin in combination with gemcitabine as a candidate for use in improved anticancer regimens.

Article Published Date : Jan 10, 2016
Study Type : In Vitro Study
Additional Links
Substances : Fisetin : CK(173) : AC(112), Flavonoids : CK(1616) : AC(523)
Diseases : Cholangiocarcinoma : CK(96) : AC(21)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Antiproliferative : CK(65) : AC(52), Apoptotic, Chemotherapeutic, Chemotherapeutic Synergy: Gemcitabine : CK(39) : AC(29), Cholangiocarcinoma, Fisetin, Flavonoids

This study confirms the potential of modified pectin to improve chemotherapeutic cancer treatments.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Modified Citrus Pectin : CK(57) : AC(15)
Diseases : Liver Cancer : CK(1953) : AC(852), Lung Cancer : CK(1741) : AC(742)
Pharmacological Actions : Apoptotic : CK(5217) : AC(3846), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Apoptotic, Chemotherapeutic, liver cancer, lung cancer, Modified Citrus Pectin

This study provides evidence that blueberries may be unique sources for anti-AML therapy.

Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Blueberry : CK(512) : AC(174)
Diseases : Acute Myeloid Leukemia : CK(162) : AC(87)
Pharmacological Actions : Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Acute Myeloid Leukemia, Blueberry, Chemotherapeutic

Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia.

Article Published Date : Jan 01, 2018
Study Type : In Vitro Study
Additional Links
Substances : Vitamin C : CK(3397) : AC(792), Vitamin C: Intravenous : CK(147) : AC(25)
Diseases : Acute Myeloid Leukemia : CK(162) : AC(87)
Pharmacological Actions : Antiproliferative : CK(4773) : AC(3450), Apoptotic : CK(5217) : AC(3846), Cell cycle arrest : CK(1289) : AC(1006), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Acute Myeloid Leukemia, Antiproliferative : CK(65) : AC(52), Apoptotic, Cell cycle arrest, Chemotherapeutic, Natural Substance/Drug Synergy : CK(352) : AC(142), Vitamin C : CK(1) : AC(1), Vitamin C: Intravenous

Vitamin K has been shown to suppress the growth of liver cancer cells.

Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Vitamin K2 : CK(383) : AC(50)
Diseases : Liver Cancer : CK(1953) : AC(852)
Pharmacological Actions : Antineoplastic Agents : CK(1594) : AC(982), Apoptotic : CK(5217) : AC(3846), Chemotherapeutic : CK(397) : AC(152)
Additional Keywords : Antineoplastic Agents : CK(75) : AC(33), Apoptotic, Chemotherapeutic, liver cancer, Natural Substance/Drug Synergy : CK(352) : AC(142), Vitamin K2 : CK(1) : AC(1)

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