Results for Bcl-2 protein down-regulation

An extract of Lotus may be a powerful agent against colon cancer cells.

Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Lotus : CK(153) : AC(108)
Diseases : Colon Cancer : CK(1217) : AC(742)
Pharmacological Actions : Apoptotic : CK(5217) : AC(3846), Bcl-2 protein down-regulation : CK(419) : AC(295), Bcl-xL down-regulation : CK(1) : AC(1), Cyclooxygenase 2 Inhibitors : CK(1114) : AC(645), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(551) : AC(315), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(543) : AC(337), NF-kappaB Inhibitor : CK(2446) : AC(1436)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, COLON CANCER, Lotus, Plant Extracts : CK(11762) : AC(4236)

Carnosic acid cooperates with tamoxifen to induce apoptosis in breast cancer cells.

Article Published Date : Apr 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Carnosic Acid : CK(39) : AC(27)
Diseases : Breast Cancer : CK(5066) : AC(1738)
Pharmacological Actions : Apoptotic : CK(5217) : AC(3846), Bcl-2 protein down-regulation : CK(419) : AC(295), Bcl-xL down-regulation : CK(1) : AC(1)
Additional Keywords : Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(2) : AC(1), Carnosic Acid, Synergy with Tamoxifen : CK(6) : AC(5)
Problem Substances : Tamoxifen : CK(338) : AC(51)

Ganoderma lucidum triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas.

Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom : CK(277) : AC(138)
Diseases : Breast Cancer : CK(5066) : AC(1738), Skin Cancer : CK(1175) : AC(495)
Pharmacological Actions : Anticarcinogenic Agents : CK(1577) : AC(756), Apoptotic : CK(5217) : AC(3846), Bcl-2 protein down-regulation : CK(419) : AC(295), Bcl-xL down-regulation : CK(1) : AC(1), Chemopreventive : CK(4220) : AC(1326), Cyclin D1 Down-Regulation : CK(42) : AC(28)
Additional Keywords : Anticarcinogenic Agents, Apoptotic, Bcl-2 protein down-regulation, Bcl-xL down-regulation, Breast Cancer : CK(2) : AC(1), Chemopreventive, Cyclin D1 Down-Regulation, Reishi Mushroom, skin cancer

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