Latest GMI Study Abstracts

Latest GMI Study Abstracts

The protective effect of hyperoside on carbon tetrachloride-induced chronic liver fibrosis.

Article Published Date : Sep 04, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Chemically-Induced Liver Damage : CK(1565) : AC(721), Lipid Peroxidation : CK(1632) : AC(631), Liver Cirrhosis : CK(516) : AC(101)
Pharmacological Actions : Anti-Fibrotic : CK(924) : AC(463), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264)

Hyperoside protects against chronic mild stress-induced learning and memory deficits.

Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Learning disorders : CK(338) : AC(106), Memory Disorders : CK(1067) : AC(339)
Pharmacological Actions : Neuroprotective Agents : CK(10404) : AC(4396)

Hyperoside inhibits lipopolysaccharide-induced inflammatory responses in microglial cells via p38 and NFκB pathways.

Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Inflammation : CK(9572) : AC(3089), Lipopolysaccharide-Induced Toxicity : CK(1764) : AC(1073)
Pharmacological Actions : Anti-Inflammatory Agents : CK(20859) : AC(8334), Interleukin-1 beta downregulation : CK(3041) : AC(1567), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(6736) : AC(2815)

Hyperoside pre-treatment prevents glomerular basement membrane damage in diabetic nephropathy.

Article Published Date : Jan 24, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Diabetic Nephropathy : CK(707) : AC(277)
Pharmacological Actions : Renoprotective : CK(2404) : AC(1075)

The effects of hyperoside on apoptosis and the expression of Fas/FasL and survivin in SW579 human thyroid squamous cell carcinoma.

Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Squamous cell carcinoma : CK(427) : AC(218), Thyroid Cancer : CK(385) : AC(117)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304), Survivin Down-Regulation : CK(15) : AC(13)

Hyperoside inhibits biofilm formation of Pseudomonas aeruginosa.

Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Pseudomonas aeruginosa : CK(304) : AC(238)
Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251)
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

Hyperoside significantly suppressed the invasion and migration of A549 cells.

Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Lung Cancer : CK(2308) : AC(999)
Pharmacological Actions : Anti-metastatic : CK(1972) : AC(1481)

Effect of hyperoside on the apoptosis of A549 human non‑small cell lung cancer cells and the underlying mechanism.

Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Carcinoma: Non-Small-Cell Lung : CK(264) : AC(161)
Pharmacological Actions : Apoptotic : CK(6986) : AC(5304)

Inhibitory effect of hyperoside isolated from Zanthoxylum bungeanum leaves on SW620 human colorectal cancer cells.

Article Published Date : Jul 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Colorectal Cancer : CK(3666) : AC(1651)
Pharmacological Actions : Antiproliferative : CK(6801) : AC(5032), Apoptotic : CK(6986) : AC(5304), Tumor Suppressor Protein p53 Upregulation : CK(585) : AC(431)

Anti-hypoglycemic and hepatocyte-protective effects of hyperoside against high-carbohydrate/high-fat diet and alloxan-induced diabetes.

Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(2352) : AC(870)
Diseases : Diabetes Mellitus: Type 2 : CK(8552) : AC(1714), High Fat Diet : CK(1267) : AC(602)
Pharmacological Actions : Anti-Apoptotic : CK(2905) : AC(1672), Antioxidants : CK(21528) : AC(8856), Hepatoprotective : CK(5098) : AC(2264), Hypoglycemic Agents : CK(5366) : AC(1338), NF-kappaB Inhibitor : CK(3536) : AC(2098)
Additional Keywords : Plant Extracts : CK(14140) : AC(5210)

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