Abstract Title:

Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes.

Abstract Source:

Int J Food Sci Nutr. 2012 Mar 5. Epub 2012 Mar 5. PMID: 22385048

Abstract Author(s):

P C Lekshmi, Ranjith Arimboor, P S Indulekha, A Nirmala Menon

Article Affiliation:

Agroprocessing and Natural Products Division, National Institute for Interdisciplinary Science and Technology (CSIR) , Thiruvananthapuram, Kerala , India.

Abstract:

Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than the reference standard drug acarbose. Drying of rhizomes was found to enhanceα-glucosidase (IC(50) = 1.32-0.38 μg/ml) and α-amylase (IC(50) = 64.7-34.3 μg/ml) inhibitory capacities of volatile oils. Ar-Turmerone, the major volatile component in the rhizome also showed potent α-glucosidase (IC(50) = 0.28 μg) and α-amylase (IC(50) = 24.5 μg) inhibition.

Study Type : In Vitro Study

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