"Synthesis and in vitro Efficacy Studies of Silver Carbene Complexes on Biosafety Level 3 Bacteria." - GreenMedInfo Summary
Article Publish Status: FREE
Abstract Title:
Synthesis and in vitro Efficacy Studies of Silver Carbene Complexes on Biosafety Level 3 Bacteria.
Abstract Source:
Eur J Inorg Chem. 2009 May 1 ;2009(13):1739-1745. PMID: 20160993
Article Affiliation:
Department of Chemistry, University of Akron, Akron, OH 44325-3601, USA.
Abstract:
A series of N-heterocyclic carbene silver complexes have been synthesized and tested against the select group of bio-safety level 3 bacteria Burkholderia pseudomallei, Burkholderia mallei, Bacillus anthracis, methicillin-resistant Staphylococcus aureus and Yersinia pestis. Minimal inhibitory concentrations, minimal bactericidal and killing assays demonstrated the exceptional efficacy of the complexes against these potentially weaponizable pathogens.
Article Published Date : May 01, 2009
Study Type : Bacterial
Additional Links
Substances : Silver Compouds : CK(2) : AC(2)
Diseases : Bacteria: Weaponized : CK(2) : AC(2), Bubonic Plague : CK(7) : AC(5), MRSA : CK(324) : AC(139)
Pharmacological Actions : Anti-Bacterial Agents : CK(2088) : AC(821)
