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Abstract Title:

Therapeutic effects of Crocin in autoimmune diseases: A review.

Abstract Source:

Biofactors. 2019 Aug 20. Epub 2019 Aug 20. PMID: 31430413

Abstract Author(s):

Shahla Korani, Mitra Korani, Thozhukat Sathyapalan, Amirhossein Sahebkar

Article Affiliation:

Shahla Korani

Abstract:

The immune system when acts against selfmolecules results in an imbalance in immunologic tolerance leading to the development of several autoimmune diseases (ADs) such as rheumatoid arthritis, asthma, ulcerative colitis, type 1 diabetes, and multiple sclerosis. Improved recognition of the mechanisms of ADs has led to the advancement of the management of these diseases. The principal mediators of ADs are inflammatory molecules. The herbal medicines due to their antioxidant and antiinflammatory properties have an important role in the management of ADs. Crocin is the principal chemical component extracted from saffron, which is a medicinal plant. This review focuses on the therapeutic effects of Crocin in various ADs.

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