Abstract Title:

[In vitro experimental study on the effect of resveratrol against several kinds of respiroviruses].

Abstract Source:

Zhong Yao Cai. 2008 Sep;31(9):1388-90. PMID: 19180966

Abstract Author(s):

Wen-Da Guan, Zi-Feng Yang, Ni Liu, Sheng Qin, Feng-Xue Zhang, Yu-Tong Zhu

Article Affiliation:

Molecular Immunology and Antibody Engineering Center, Jinan University, Guangzhou 510632, China.

Abstract:

OBJECTIVE: To observe the cytopathogenic inhibitory effect of resveratrol on vary respiroviruses and explore the mechanism of resveratrol against viruses. METHODS: MDCK, A549, HEp-2 cell and MRC-5 were infected with Influenza virus type A FM1 strain, rhinovirus type R14, RS virus, AD virus type 7 separately, and the antiviral activity of resveratrol were observed. RESULTS: Resveratrol significantly inhibited cytopathogenic effect of AD virus type 7 at the concentration 120 microg/ml. No significant cytopathogenic effect of Resveratrol inhibiting Influenza virus type A FM1 strain, Rhinovirus type R14, RS virus on separate cells was observed. CONCLUSION: It is concluded that resveratrol is effective on inhibiting AD virus type 7 in vitro, however, its mechanism is needed for further study.

Study Type : In Vitro Study

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