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Abstract Title:

Green tea consumption and risk of hematologic neoplasms: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study).

Abstract Source:

Cancer Causes Control. 2019 Aug 26. Epub 2019 Aug 26. PMID: 31452000

Abstract Author(s):

Midori Takada, Kazumasa Yamagishi, Hiroyasu Iso, Akiko Tamakoshi

Article Affiliation:

Midori Takada

Abstract:

PURPOSE: Experimental studies suggested that green tea may have an anticancer effect on hematologic neoplasms. However, few prospective studies have been conducted.

METHODS: A total of 65,042 individuals aged 40-79 years participated in this study and completed a self-administered questionnaire about their lifestyle and medical history at baseline (1988-1990). Of these, 52,462 individuals living in 24 communities with information on incident hematologic neoplasms available in the cancer registry, who did nothave a history of cancer and provided valid information on frequency of green tea consumption, were followed through 2009. Hazard ratios (HRs) and 95% confidence intervals (CIs) for the incidence of hematologic neoplasms according to green tea consumption were analyzed.

RESULTS: The incidence of hematologic neoplasms during a median follow-up of 13.3 years was 323. Compared with the never-drinkers of green tea, the multivariate HRs and 95% CIs for total hematologic neoplasms in green tea drinkers of ≤ 2 cups/day, 3-4 cups/day, and ≥ 5 cups/day were 0.65 (0.42-1.00), 0.73 (0.47-1.13), and 0.63 (0.42-0.96), respectively. The association wasmore prominent for acute myeloid leukemias and follicular lymphomas.

CONCLUSIONS: The present cohort study suggests a protective effect of green tea against hematologic neoplasms, especially acute myeloid leukemias.

Study Type : Human Study

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Sayer Ji
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