Abstract Title:

In vitro activity of a Solanum tuberosum extract against mammary carcinoma cells.

Abstract Source:

Planta Med. 2001 Mar;67(2):164-6. PMID: 11301867

Abstract Author(s):

M S De Lorenzo, P L Lorenzano Menna, D F Alonso, D E Gomez

Abstract:

We investigated the antitumor properties of a Solanum tuberosum extract (STE) on F3II mouse mammary carcinoma cells. STE significantly inhibited adhesion on fibronectin-coated surfaces and blocked migration of tumor cells in vitro. A major gelatinolytic activity (gelatinase) of 82 kD was identified in STE by zymographic analysis and characterized by exposure to different experimental conditions. Proteolytic activity of STE may be responsible, at least in part, for the in vitro effects on mammary carcinoma cells.

Study Type : In Vitro Study

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