Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent. - GreenMedInfo Summary
n/a
Abstract Title:
Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent.
Abstract Source:
AIDS. 2002 Apr 12 ;16(6):939-41. PMID: 11919502
Article Affiliation:
Gianfranco Fassina
Abstract:
Epigallocatechin-3-gallate (EGCG), one of the components of green tea, has been suggested to have antiviral activity. To determine the effects of EGCG on HIV infection, peripheral blood lymphocytes were incubated with either LAI/IIIB or Bal HIV strains and increasing concentrations of EGCG. EGCG strongly inhibited the replication of both virus strains as determined by reverse transcriptase and p24 assays on the cell supernatants.
Article Published Date : Apr 11, 2002
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate) : CK(890) : AC(477)
Diseases : HIV Infections : CK(849) : AC(260)
Pharmacological Actions : Anti-HIV Agents : CK(111) : AC(63), Reverse Transcriptase Inhibitors : CK(42) : AC(24)
