Abstract Title:

Constituents of Eriobotrya japonica. A study of their antiviral properties.

Abstract Source:

J Nat Prod. 1992 Aug;55(8):1067-73. PMID: 1279126

Abstract Author(s):

N De Tommasi, F De Simone, C Pizza, N Mahmood, P S Moore, C Conti, N Orsi, M L Stein

Article Affiliation:

Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli, Italy.


The CHCl3 extract of Eriobotrya japonica from an Italian source was shown to contain four new triterpene esters, namely, 23-trans-p-coumaroyltormentic acid [1], 23-cis-p-coumaroyltormentic acid [2], 3-O-trans-caffeoyltormentic acid [3], and 3-O-trans-p-coumaroylrotundic acid [4], in addition to three common ursolic acid derivatives 5, 6, and 7. An investigation of the antiviral properties of compounds 1-7 revealed that only 3 significantly reduced rhinovirus infection. The compounds were ineffective towards human immunodeficiency virus type 1 (HIV-1) and Sindbis virus replication.

Study Type : In Vitro Study

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