Abstract Title:

Lactose intolerance and risk of lung, breast and ovarian cancers: aetiological clues from a population-based study in Sweden.

Abstract Source:

Br J Cancer. 2014 Oct 14. Epub 2014 Oct 14. PMID: 25314053

Abstract Author(s):

J Ji, J Sundquist, K Sundquist

Article Affiliation:

J Ji

Abstract:

Background:Individuals with lactose intolerance are recommended to avoid milk or dairy products, which may affect the development of cancer.Methods:We identified individuals with lactose intolerance from several Swedish Registers linked to the Swedish Cancer Registry to calculate standardised incidence ratios (SIRs) for cancers in the breast, lung, and ovary.Results:A total of 22 788 individuals with lactose intolerance were identified, and their risks of lung (SIR=0.55), breast (SIR=0.79), and ovarian (SIR=0.61) cancers were significantly decreased. Cancer incidences in the siblings and parents of individuals with lactose intolerance were similar to those in the generalpopulation.Conclusions:In this large cohort study, people with lactose intolerance, characterised by low consumption of milk and other dairy products, had decreased risks of lung, breast, and ovarian cancers, but the decreased risks were not found in their family members, suggesting that the protective effects against these cancers may be related to their specific dietary pattern.British Journal of Cancer advance online publication, 14 October 2014; doi:10.1038/bjc.2014.544 www.bjcancer.com.

Study Type : Human Study

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Sayer Ji
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