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Article Publish Status: FREE
Abstract Title:

N-acetycysteine: A potential therapeutic agent in COVID-19 infection.

Abstract Source:

Med Hypotheses. 2020 Jul 24 ;144:110133. Epub 2020 Jul 24. PMID: 32758904

Abstract Author(s):

N Jaiswal, M Bhatnagar, H Shah

Article Affiliation:

N Jaiswal

Abstract:

COVID-19 is an overwhelming pandemic which has shattered the whole world. Lung injury being the main clinical manifestation, it is likely to cause COPD (chronic obstructive pulmonary disease) and ARDS (acute respiratory distress syndrome). The possible cause behind this might be redox imbalance due to viral infection. Elevation in Glutathione (GSH) levels by administration of its promolecule might be effective. N-acetylcysteine is one such drug with potency to scavenge Reactive Oxygen Species, least side effects, and an effective precursor of glutathione. Consequently we hypothesize that N-acetylcysteine along with the conventional treatment may be treated as a potential therapeutic solution in cases of COVID-19 patients.

Study Type : Commentary

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Sayer Ji
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