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Abstract Title:

Assessment of antidiabetic potential ofpeel extract and its fractions in experimental animals and characterisation of its bioactive compounds by HPTLC.

Abstract Source:

Arch Physiol Biochem. 2019 Nov 5:1-13. Epub 2019 Nov 5. PMID: 31687854

Abstract Author(s):

Navghare Vijay, Dhawale Shashikant, Phanse Mohini

Article Affiliation:

Navghare Vijay

Abstract:

is a rich source of nutritional food with acclaimed therapeutic uses. Banana pulp has been reported to possess antidiabetic properties. The present study aimed to investigate antidiabetic potential ofpeels and its fractions along with diabetic complications. Animals were divided into various groups ( = 6), EMA 100, 200 and 400 mg/kg/day and various fractions 50 and 100 mg/kg/day along with vehicle administered orally to alloxan-induced diabetic rats ( = 6) for 21 days for extract and for 7 days for fractions.possess antidiabetic potential by reducing plasma glucose by utilising glucose in the periphery and production of hepatic glycogen and further reduce protein catabolism which is responsible for improvement in body weight along with reduction in diabetic complications such as dyslipidemia, peripheral neuropathy and nephropathy. Protective role ofin treatment of diabetes and its complications.

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