Abstract Title:

Pharmacological effects of lavandulifolioside from Leonurus cardiaca.

Abstract Source:

J Ethnopharmacol. 2002 Apr;80(1):85-90. PMID: 11891090

Abstract Author(s):

Katarzyna Miłkowska-Leyck, Barbara Filipek, Halina Strzelecka

Article Affiliation:

Department of Pharmacognosy, Faculty of Pharmacy, Medical Academia, 02097, Warsaw, Poland.

Abstract:

Lavandulifolioside was detected for the first time in Leonurus cardiaca var. vulgaris [Moench] Briquet (Lamiaceae). The isolation was performed from the butanolic extract of the aerial parts and the identification by NMR and MS. The pharmacological properties of lavandulifolioside consist of significant negative chronotropism, prolongation of the P-Q, Q-T intervals and QRS complex, and decrease of blood pressure. Contrary to the butanolic extract lavandulifolioside did not reduce the spontaneous locomotor activity. In conclusion, the pharmacological pattern of lavandulifolioside did not explain the pharmacological effects of L. cardiaca L. alone.

Study Type : Animal Study
Additional Links
Pharmacological Actions : Hypotensive : CK(435) : AC(59)

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