n/a
Article Publish Status: FREE
Abstract Title:

Effect of high-dose ginsenoside complex (UG0712) supplementation on physical performance of healthy adults during a 12-week supervised exercise program: A randomized placebo-controlled clinical trial.

Abstract Source:

J Ginseng Res. 2018 Apr ;42(2):192-198. Epub 2017 Apr 5. PMID: 29719466

Abstract Author(s):

Eon Sook Lee, Yun Jun Yang, Jun Hyung Lee, Yeong Sook Yoon

Article Affiliation:

Eon Sook Lee

Abstract:

Background: Ginseng has been used as an ergogenic agent, although evidence for its effectiveness is weak. A randomized, double-blind, placebo-controlled clinical trial was conducted to evaluate the effect of a ginsenoside complex (UG0712) on changes in exercise performance.

Methods: Sedentary individuals (  117) were randomly assigned into one of three groups: low-dose ginsenoside supplementation (100 mg/d,  39), high-dose ginsenoside supplementation (500 mg/d,  39), or a placebo group (500 mg/d,  39). All participants underwent a supervised 12-wk aerobic and resistance exercise training course. To assess the effects of supplementation on physical performance, maximal oxygen consumption (VOmax), anaerobic threshold (AT), lactic acid, and muscle strength of the dominant knee were measured at baseline, every visit, and after the training program.

Results: Both ginsenoside groups showed significant increases in VOmax and muscular strength during exercise training. There were no definite changes in AT and lactic acid levels over time. After exercise training, there were definite differences in the VOmax (28.64.9 to 33.7 ± 4.9 ml/kg/min in high-dose group vs. 30.4 ± 6.7 to 32.8 ± 6.6 ml/kg/min in placebo,  0.029) and AT (19.3 ± 4.2 to 20.9 ± 3.5 ml/kg/min in high-dose group vs. 20.0 ± 5.1 to 20.0 ± 4.9 ml/kg/min in placebo,  0.038) between the high-dose ginsenoside and placebo groups. However, there was no difference in VOmax between the low-dose ginsenoside and placebo groups (  0.254). There were no differences in muscular strength during exercise training among the three groups.

Conclusion: High-dose ginsenoside supplementation (UG0712) augmented the improvement of aerobic capacity by exercise training.

Study Type : Human Study

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.