Ginsenoside has an anti-neuroinflammation effect in a rat model of Alzheimer disease. - GreenMedInfo Summary

Abstract Title:

Anti-neuroinflammation effect of ginsenoside Rbl in a rat model of Alzheimer disease.

Abstract Source:

Neurosci Lett. 2011 Jan 3;487(1):70-2. Epub 2010 Oct 7. PMID: 20933058

Abstract Author(s):

Yulin Wang, Jing Liu, Zhongmin Zhang, Pengxiang Bi, Zhiguo Qi, Chaodong Zhang

Article Affiliation:

China Medical University, The First Affiliated Hospital, Department of Neurology, Shen Yang, China.

Abstract:

The present work explored the anti-neuroinflammation effects of Ginseng Rb1 in a rat model of Alzheimer disease produced by ventricle injection of Aβ1-42. Aβ1-42 injection induces loss of learning and memory behavior of rats in Morris water maze, which could be reversed with Rb1 treatment. Further, Rb1 reversed the changes in several direct or indirect neuroinflammation markers in the hippocampus, suggesting that this could be a potential underlying mechanism and a way to develop anti-aging drugs.

Article Published Date : Jan 03, 2011

Study Type : Animal Study

Additional Links

Substances : Ginsenosides : CK(1024) : AC(597)

Diseases : Alzheimer's Disease : CK(2442) : AC(871), Brain Inflammation : CK(686) : AC(352)

Pharmacological Actions : Anti-Inflammatory Agents : CK(12461) : AC(4729), Neuroprotective Agents : CK(6374) : AC(2801)

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version
Send to friend
PDF version

Ginsenoside has an anti-neuroinflammation effect in a rat model of Alzheimer disease. - GreenMedInfo Summary

Print Options

Key Research Topics

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.