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Abstract Title:

Four new phenolic compounds from the fruit of(Cornaceae) and their anti-inflammatory activity in RAW 264.7 cells.

Abstract Source:

Nat Prod Res. 2021 Feb 16:1-7. Epub 2021 Feb 16. PMID: 33593150

Abstract Author(s):

Nguyen Thi Thu, Nguyen The Hung, Nguyen Thi Thuy An, Le Ba Vinh, Bui Thi Binh, Nguyen Thi Bich Thu, Nguyen Minh Khoi, Do Thi Ha

Article Affiliation:

Nguyen Thi Thu

Abstract:

Using various chromatographic methods, four new phenolics, coroffesters A-D () were isolated from the fruit of(Cornaceae). Their structures () were elucidated unambiguously by spectroscopic methods such as one- and two-dimensional nuclear magnetic resonance (1 D- and 2 D-NMR) spectroscopy and high-resolution electrospray ionization mass spectrometry (HR-ESI-MS). The anti-inflammatory activity of the isolated compounds was also evaluated. All compounds () showed moderate inhibitory activity against NO production in a dose-dependent manner in RAW 264.7 cells.

Study Type : In Vitro Study

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