Abstract Title:

Flaxseed for Health and Disease: Review of Clinical Trials.

Abstract Source:

Comb Chem High Throughput Screen. 2020 May 21. Epub 2020 May 21. PMID: 32436825

Abstract Author(s):

Mersedeh Shayan, Safa Kamalian, Amirhossein Sahebkar, Zahra Tayarani Najaran

Article Affiliation:

Mersedeh Shayan


BACKGROUND: Flaxseed (Linum usitatissimum) is an oil-based seed which contains high amounts of alpha-linoleic acid, linoleic acid, lignans, fiber and many other bioactive components which is suggested for healthier life. Nowadays flaxseed is known as a remarkable functional food with different health benefits for humans and protects against cardiovascular disease, diabetes, dyslipidemia, obesity and altogether metabolic syndrome.

OBJECTIVES AND METHODS: To review the bioactive components of flaxseed and their potential health effects, PubMed and Scopus were searched from commencement to July 2019. Keywords including: 'flaxseed', 'Linum usitatissimum', 'metabolic syndrome', 'obesity', 'inflammation', 'insulin resistance', 'diabetes', 'hyperlipidemia' and 'menopause' were searched in the databases with varying combinations.

CONCLUSIONS: Consumption of flaxseed in different forms has valuable effect and protects against cardiovascular disease, hypertension, diabetes, dyslipidemia, inflammation and some other complications. Flaxseed can serve as a promising candidate for management of metabolic syndrome to control blood lipid levels, fasting blood sugar, insulin resistance, body weight, waist circumference, body mass and blood pressure.

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