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Abstract Title:

Extremely low frequency magnetic field induces oxidative stress in mouse cerebellum.

Abstract Source:

Gen Physiol Biophys. 2011 Dec ;30(4):415-21. PMID: 22131325

Abstract Author(s):

Li Y Chu, Jong H Lee, Yun S Nam, Yu J Lee, Won-Hee Park, Byung-Cheon Lee, Daejin Kim, Yoon H Chung, Ji H Jeong

Article Affiliation:

Li Y Chu

Abstract:

We have investigated whether extremely low frequency magnetic field (ELF-MF) induces lipid peroxidation and reactive oxygen species in mouse cerebellum. After exposure to 60 Hz ELF-MF at 2.3 mT intensity for 3 hours, there was a significant increase in malondialdehyde level and hydroxyl radical. ELF-MF significantly induced concomitant increase in superoxide dismutase without alteration in glutathione peroxidase activity. While glutathione contents were not altered, ascorbic acid levels were significantly decreased by ELF-MF exposure. These results indicate that ELF-MF may induce oxidative stress in mouse cerebellum. However, the mechanism remains further to be characterized.

Study Type : Animal Study

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