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Abstract Title:

Emerging antitumor activities of the bitter melon (Momordica charantia).

Abstract Source:

Curr Protein Pept Sci. 2018 Jun 21. Epub 2018 Jun 21. PMID: 29932035

Abstract Author(s):

Evandro Fei Fang, Lynn Froetscher, Morten Scheibye-Knudsen, Vilhelm A Bohr, Tzi Bun Ng

Article Affiliation:

Evandro Fei Fang

Abstract:

Bitter melon or bitter gourd (Momordica charantia) is a common vegetable in Asia and it is distinctive for its bitter taste. As an ingredient in folk medicine, research from different laboratories in recent years supports its potential medicinal applications with anti-tumor, anti-diabetic, anti-HIV activities in both in vitro and animal studies. In this short review, we summarize herein the recent progress in the antitumor aspect of bitter melon with a focus on the underlying molecular mechanisms. Further mechanistic studies as well as clinical trials are necessary to further verify its medicinal applications.

Study Type : Review

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Sayer Ji
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