Abstract Title:

Flaxseed (linum usitatissimum) flour contributes to bone health in adult male rats.

Abstract Source:

Nutrition. 2018 May ;49:48-50. Epub 2017 Dec 7. PMID: 29494999

Abstract Author(s):

Duque Coutinho de Abreu Maíra, Rozeno Pessoa Letícia, Luanna Rodrigues da Costa, Bianca Ferolla da Camara Boueri, Ribeiro Pessanha Carolina, Aline D'Avila Pereira, Danielle Cavalcante Ribeiro, Eduardo Moreira da Silva, Carlos Alberto Soares da Costa, Teles Boaventura Gilson

Article Affiliation:

Duque Coutinho de Abreu Maíra


OBJECTIVE: This study evaluated effects of flaxseed flour diet on bone health in adult Wistar male rats at 180 d.

METHODS: After birth, pups were randomly assigned: Control (C, n = 12) and flaxseed flour (FF, n = 12) diet during lactation period. At 21 d, pups were weaned and they continued to receive the control and experimental diet, respectively. At 180 d, body length, total bone structure, and femur and lumbar vertebrae were evaluated by dual-energy X-ray absorptiometry. Femoral and lumbar vertebra dimensions, biomechanical properties of femur, and serum osteocalcin were measured.

RESULTS: FF produced greater (P <0.05) total (+3.4%) and spine (+5.9%) bone mineral density, total (+10%) and spine (+12%) bone mineral content, total bone area (+8.7%), and osteocalcin (+82%). As to femur, FF produced greater (P <0.05) width of diaphysis (+8.1%), bone mineral density (+5.2%), maximum force (+10.6%), breaking strength (+12.9%), and stiffness (+23%).

CONCLUSION: This experimental study found that a diet containing flaxseed flour contributed to bone mineral density and femur resistance at 180 d.

Study Type : Animal Study
Additional Links
Pharmacological Actions : Osteoprotective : CK(20) : AC(6)

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