Cannaboids have antitumor activity. - GreenMedInfo Summary

Abstract Title:

Antitumorigenic effects of cannabinoids beyond apoptosis.

Abstract Source:

J Pharmacol Exp Ther. 2009 Nov 4. PMID: 19889794

Abstract Author(s):

Nadine Freimuth, Robert Ramer, Burkhard Hinz

Abstract:

According to the World Health Organization the cases of death caused by cancer will have been doubled until the year 2030. By 2010 cancer is expected to be the cause of death number one. It is therefore necessary to explore novel approaches for the treatment of cancer. During past years the antitumorigenic effects of cannabinoids have emerged as an exciting field in cancer research. Apart from their proapoptotic and antiproliferative action, recent research has shown that cannabinoids may likewise affect tumor cell angiogenesis, migration, invasion, adhesion and metastasation. This review will summarize the data concerning the influence of cannabinoids on these locomotive processes beyond modulation of cancer cell apoptosis and proliferation. The findings discussed here provide a new perspective on the antitumorigenic potential of cannabinoids.

Study Type : Commentary

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Sayer Ji
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