Article Publish Status: FREE
Abstract Title:

Ascorbic acid: a promising agent in chronic kidney disease?

Abstract Source:

Clin Kidney J. 2018 Aug ;11(4):530-531. Epub 2018 Jun 26. PMID: 30094017

Abstract Author(s):

Salih Karahan, Baris Afsar, Mehmet Kanbay

Article Affiliation:

Salih Karahan


Asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, is related with impaired endothelial function and poor outcomes in chronic kidney disease (CKD) patients. In addition, oxidative stress and inflammation are also a common problem in CKD patients, and both have an important role in the development and progression of atherosclerosis and increased cardiovascular events in CKD. Ascorbic acid might be a promising agent in CKD for improving outcome by decreasing oxidative stress and ADMA levels.

Study Type : Human Study

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Sayer Ji
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